Motif ID: MYB

Z-value: 1.911


Transcription factors associated with MYB:

Gene SymbolEntrez IDGene Name
MYB ENSG00000118513.14 MYB

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
MYBhg19_v2_chr6_+_135502466_135502489,
hg19_v2_chr6_+_135502408_135502459
0.835.1e-07Click!


Activity profile for motif MYB.

activity profile for motif MYB


Sorted Z-values histogram for motif MYB

Sorted Z-values for motif MYB



Network of associatons between targets according to the STRING database.



First level regulatory network of MYB

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_+_10441970 9.736 ENST00000274134.4
ROPN1L
rhophilin associated tail protein 1-like
chr3_-_50383096 9.534 ENST00000442887.1
ENST00000360165.3
ZMYND10

zinc finger, MYND-type containing 10

chr7_+_48075108 9.263 ENST00000420324.1
ENST00000435376.1
ENST00000430738.1
ENST00000348904.3
ENST00000539619.1
C7orf57




chromosome 7 open reading frame 57




chr19_+_5914213 5.397 ENST00000222125.5
ENST00000452990.2
ENST00000588865.1
CAPS


calcyphosine


chrY_+_22737678 5.307 ENST00000382772.3
EIF1AY
eukaryotic translation initiation factor 1A, Y-linked
chr19_+_4639514 5.090 ENST00000327473.4
TNFAIP8L1
tumor necrosis factor, alpha-induced protein 8-like 1
chr6_+_163148161 4.956 ENST00000337019.3
ENST00000366889.2
PACRG

PARK2 co-regulated

chr7_-_123174610 4.664 ENST00000324698.6
ENST00000434450.1
IQUB

IQ motif and ubiquitin domain containing

chr2_-_230579185 4.629 ENST00000341772.4
DNER
delta/notch-like EGF repeat containing
chr1_+_151682909 4.570 ENST00000326413.3
ENST00000442233.2
RIIAD1
AL589765.1
regulatory subunit of type II PKA R-subunit (RIIa) domain containing 1
Uncharacterized protein; cDNA FLJ36032 fis, clone TESTI2017069
chr11_+_61276214 4.517 ENST00000378075.2
LRRC10B
leucine rich repeat containing 10B
chr11_-_8615507 4.447 ENST00000431279.2
ENST00000418597.1
STK33

serine/threonine kinase 33

chr6_+_167412835 3.979 ENST00000349556.4
FGFR1OP
FGFR1 oncogene partner
chr16_-_75590114 3.795 ENST00000568377.1
ENST00000565067.1
ENST00000258173.6
TMEM231


transmembrane protein 231


chr15_-_56757329 3.748 ENST00000260453.3
MNS1
meiosis-specific nuclear structural 1
chr9_-_126030817 3.733 ENST00000348403.5
ENST00000447404.2
ENST00000360998.3
STRBP


spermatid perinuclear RNA binding protein


chr1_-_109656439 3.674 ENST00000369949.4
C1orf194
chromosome 1 open reading frame 194
chr21_-_47738112 3.509 ENST00000417060.1
C21orf58
chromosome 21 open reading frame 58
chr9_+_131219179 3.419 ENST00000372791.3
ODF2
outer dense fiber of sperm tails 2
chr4_-_7044657 3.253 ENST00000310085.4
CCDC96
coiled-coil domain containing 96

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 255 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.8 11.6 GO:0036159 inner dynein arm assembly(GO:0036159)
0.1 10.4 GO:0007286 spermatid development(GO:0007286)
0.6 9.7 GO:0003351 epithelial cilium movement(GO:0003351)
0.2 7.6 GO:0034453 microtubule anchoring(GO:0034453)
0.3 7.1 GO:0070286 axonemal dynein complex assembly(GO:0070286)
0.2 7.1 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.0 6.3 GO:0007224 smoothened signaling pathway(GO:0007224)
1.2 5.8 GO:0090202 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
1.3 5.3 GO:0032053 ciliary basal body organization(GO:0032053)
0.4 5.3 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.1 5.2 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.1 4.9 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 4.1 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.2 4.0 GO:0007220 Notch receptor processing(GO:0007220)
0.1 3.8 GO:0034389 lipid particle organization(GO:0034389)
0.1 3.7 GO:0007638 mechanosensory behavior(GO:0007638)
0.4 3.5 GO:1902412 regulation of mitotic cytokinesis(GO:1902412)
0.2 3.5 GO:0070986 left/right axis specification(GO:0070986)
0.0 3.5 GO:0051170 nuclear import(GO:0051170)
0.1 3.0 GO:0010738 regulation of protein kinase A signaling(GO:0010738)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 95 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 13.5 GO:0005813 centrosome(GO:0005813)
0.2 10.5 GO:0005801 cis-Golgi network(GO:0005801)
0.3 9.8 GO:0034451 centriolar satellite(GO:0034451)
0.7 8.1 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 6.9 GO:0031514 motile cilium(GO:0031514)
0.3 6.3 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.6 5.8 GO:0097255 R2TP complex(GO:0097255)
0.2 4.9 GO:0097225 sperm midpiece(GO:0097225)
0.5 4.7 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 3.9 GO:0035578 azurophil granule lumen(GO:0035578)
0.2 3.8 GO:0036038 MKS complex(GO:0036038)
0.3 3.7 GO:0001520 outer dense fiber(GO:0001520)
0.1 3.5 GO:0097542 ciliary tip(GO:0097542)
0.1 3.4 GO:0030286 dynein complex(GO:0030286)
0.1 3.2 GO:0005881 cytoplasmic microtubule(GO:0005881)
1.0 3.1 GO:0001534 radial spoke(GO:0001534)
0.3 3.0 GO:0000235 astral microtubule(GO:0000235) aster(GO:0005818)
0.1 2.8 GO:0060293 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.0 2.5 GO:0031901 early endosome membrane(GO:0031901)
0.5 2.4 GO:0098536 deuterosome(GO:0098536)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 142 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 9.8 GO:0044183 protein binding involved in protein folding(GO:0044183)
1.5 6.1 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.7 5.8 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.1 3.8 GO:0005112 Notch binding(GO:0005112)
0.0 3.8 GO:0003725 double-stranded RNA binding(GO:0003725)
0.1 3.6 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 3.2 GO:0003743 translation initiation factor activity(GO:0003743)
0.1 3.1 GO:0043014 alpha-tubulin binding(GO:0043014)
0.3 2.9 GO:0050145 nucleoside phosphate kinase activity(GO:0050145)
0.1 2.8 GO:0008171 O-methyltransferase activity(GO:0008171)
0.9 2.7 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.1 2.7 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 2.7 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.3 2.6 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 2.5 GO:0051018 protein kinase A binding(GO:0051018)
0.4 2.3 GO:0003998 acylphosphatase activity(GO:0003998)
0.1 2.3 GO:0070840 dynein complex binding(GO:0070840)
0.4 2.2 GO:0004306 ethanolamine-phosphate cytidylyltransferase activity(GO:0004306)
0.1 2.2 GO:0001671 ATPase activator activity(GO:0001671)
0.1 2.1 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)

Gene overrepresentation in C2:CP category:

Showing 1 to 20 of 22 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 5.8 PID_MYC_PATHWAY C-MYC pathway
0.0 3.1 PID_NOTCH_PATHWAY Notch signaling pathway
0.0 2.9 PID_E2F_PATHWAY E2F transcription factor network
0.0 2.6 PID_PLK1_PATHWAY PLK1 signaling events
0.0 2.5 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4
0.0 2.0 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.0 1.9 PID_TELOMERASE_PATHWAY Regulation of Telomerase
0.1 1.7 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.0 1.3 PID_FANCONI_PATHWAY Fanconi anemia pathway
0.0 1.1 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.1 0.9 PID_ANGIOPOIETIN_RECEPTOR_PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.9 PID_AURORA_B_PATHWAY Aurora B signaling
0.1 0.7 PID_FOXO_PATHWAY FoxO family signaling
0.0 0.7 PID_FCER1_PATHWAY Fc-epsilon receptor I signaling in mast cells
0.1 0.6 PID_EPO_PATHWAY EPO signaling pathway
0.0 0.6 PID_FRA_PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.5 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.0 0.5 PID_TCR_RAS_PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.5 PID_BMP_PATHWAY BMP receptor signaling
0.0 0.4 PID_ERBB4_PATHWAY ErbB4 signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 38 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 5.9 REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.1 5.7 REACTOME_EXTENSION_OF_TELOMERES Genes involved in Extension of Telomeres
0.1 4.1 REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.2 3.1 REACTOME_PURINE_CATABOLISM Genes involved in Purine catabolism
0.0 3.0 REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1 2.7 REACTOME_APC_CDC20_MEDIATED_DEGRADATION_OF_NEK2A Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.1 2.5 REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 2.0 REACTOME_METABOLISM_OF_NON_CODING_RNA Genes involved in Metabolism of non-coding RNA
0.0 1.8 REACTOME_RNA_POL_I_PROMOTER_OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 1.8 REACTOME_AUTODEGRADATION_OF_CDH1_BY_CDH1_APC_C Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C
0.0 1.5 REACTOME_GLYCEROPHOSPHOLIPID_BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.1 1.4 REACTOME_SYNTHESIS_OF_PE Genes involved in Synthesis of PE
0.0 1.4 REACTOME_PEROXISOMAL_LIPID_METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 1.3 REACTOME_LATENT_INFECTION_OF_HOMO_SAPIENS_WITH_MYCOBACTERIUM_TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 1.3 REACTOME_INTERFERON_ALPHA_BETA_SIGNALING Genes involved in Interferon alpha/beta signaling
0.2 1.1 REACTOME_BINDING_AND_ENTRY_OF_HIV_VIRION Genes involved in Binding and entry of HIV virion
0.1 1.1 REACTOME_RESOLUTION_OF_AP_SITES_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.0 1.0 REACTOME_PROCESSING_OF_INTRONLESS_PRE_MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 1.0 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.0 0.9 REACTOME_NUCLEOTIDE_LIKE_PURINERGIC_RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors