Motif ID: MYOD1

Z-value: 0.764


Transcription factors associated with MYOD1:

Gene SymbolEntrez IDGene Name
MYOD1 ENSG00000129152.3 MYOD1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
MYOD1hg19_v2_chr11_+_17741111_177411240.019.7e-01Click!


Activity profile for motif MYOD1.

activity profile for motif MYOD1


Sorted Z-values histogram for motif MYOD1

Sorted Z-values for motif MYOD1



Network of associatons between targets according to the STRING database.



First level regulatory network of MYOD1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr16_-_67427389 3.090 ENST00000562206.1
ENST00000290942.5
ENST00000393957.2
TPPP3


tubulin polymerization-promoting protein family member 3


chr10_-_13043697 2.094 ENST00000378825.3
CCDC3
coiled-coil domain containing 3
chr11_+_27062860 2.017 ENST00000528583.1
BBOX1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr16_+_67465016 1.906 ENST00000326152.5
HSD11B2
hydroxysteroid (11-beta) dehydrogenase 2
chr3_-_50383096 1.894 ENST00000442887.1
ENST00000360165.3
ZMYND10

zinc finger, MYND-type containing 10

chr2_+_85981008 1.820 ENST00000306279.3
ATOH8
atonal homolog 8 (Drosophila)
chr17_+_68165657 1.776 ENST00000243457.3
KCNJ2
potassium inwardly-rectifying channel, subfamily J, member 2
chr11_+_86511549 1.511 ENST00000533902.2
PRSS23
protease, serine, 23
chr7_-_120497178 1.421 ENST00000441017.1
ENST00000424710.1
ENST00000433758.1
TSPAN12


tetraspanin 12


chr5_-_150603679 1.410 ENST00000355417.2
CCDC69
coiled-coil domain containing 69
chr12_+_50355647 1.284 ENST00000293599.6
AQP5
aquaporin 5
chr13_-_26625169 1.208 ENST00000319420.3
SHISA2
shisa family member 2
chr7_+_107301065 1.166 ENST00000265715.3
SLC26A4
solute carrier family 26 (anion exchanger), member 4
chr11_+_27062272 1.147 ENST00000529202.1
ENST00000533566.1
BBOX1

butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1

chr4_+_165675269 1.139 ENST00000507311.1
RP11-294O2.2
RP11-294O2.2
chr11_+_27062502 1.084 ENST00000263182.3
BBOX1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chrX_-_99665262 1.040 ENST00000373034.4
ENST00000255531.7
PCDH19

protocadherin 19

chr3_+_111393659 0.998 ENST00000477665.1
PLCXD2
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr1_+_162351503 0.941 ENST00000458626.2
C1orf226
chromosome 1 open reading frame 226
chr17_-_46035187 0.935 ENST00000300557.2
PRR15L
proline rich 15-like
chr5_-_159739532 0.922 ENST00000520748.1
ENST00000393977.3
ENST00000257536.7
CCNJL


cyclin J-like


chr1_+_87794150 0.921 ENST00000370544.5
LMO4
LIM domain only 4
chr6_-_24911195 0.912 ENST00000259698.4
FAM65B
family with sequence similarity 65, member B
chr16_-_84273304 0.908 ENST00000308251.4
ENST00000568181.1
KCNG4

potassium voltage-gated channel, subfamily G, member 4

chr1_+_60280458 0.872 ENST00000455990.1
ENST00000371208.3
HOOK1

hook microtubule-tethering protein 1

chr2_-_220435963 0.872 ENST00000373876.1
ENST00000404537.1
ENST00000603926.1
ENST00000373873.4
ENST00000289656.3
OBSL1




obscurin-like 1




chr19_-_7990991 0.851 ENST00000318978.4
CTXN1
cortexin 1
chr7_-_73184588 0.835 ENST00000395145.2
CLDN3
claudin 3
chr22_-_36013368 0.833 ENST00000442617.1
ENST00000397326.2
ENST00000397328.1
ENST00000451685.1
MB



myoglobin



chr4_-_23891693 0.833 ENST00000264867.2
PPARGC1A
peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
chr10_+_94608245 0.811 ENST00000443748.2
ENST00000260762.6
EXOC6

exocyst complex component 6

chr20_+_58179582 0.806 ENST00000371015.1
ENST00000395639.4
PHACTR3

phosphatase and actin regulator 3

chr16_+_83932684 0.800 ENST00000262430.4
MLYCD
malonyl-CoA decarboxylase
chr6_-_33714752 0.799 ENST00000451316.1
IP6K3
inositol hexakisphosphate kinase 3
chr2_-_154335300 0.792 ENST00000325926.3
RPRM
reprimo, TP53 dependent G2 arrest mediator candidate
chr7_+_73442487 0.759 ENST00000380575.4
ENST00000380584.4
ENST00000458204.1
ENST00000357036.5
ENST00000417091.1
ENST00000429192.1
ENST00000442310.1
ENST00000380553.4
ENST00000380576.5
ENST00000428787.1
ENST00000320399.6
ELN










elastin










chr1_+_89990431 0.750 ENST00000330947.2
ENST00000358200.4
LRRC8B

leucine rich repeat containing 8 family, member B

chr1_-_47655686 0.749 ENST00000294338.2
PDZK1IP1
PDZK1 interacting protein 1
chr19_-_47137942 0.747 ENST00000300873.4
GNG8
guanine nucleotide binding protein (G protein), gamma 8
chr9_+_36136700 0.747 ENST00000396613.3
ENST00000377959.1
ENST00000377960.4
GLIPR2


GLI pathogenesis-related 2


chr1_-_154928562 0.740 ENST00000368463.3
ENST00000539880.1
ENST00000542459.1
ENST00000368460.3
ENST00000368465.1
PBXIP1




pre-B-cell leukemia homeobox interacting protein 1




chr3_-_66024213 0.717 ENST00000483466.1
MAGI1
membrane associated guanylate kinase, WW and PDZ domain containing 1
chr2_+_223289208 0.710 ENST00000321276.7
SGPP2
sphingosine-1-phosphate phosphatase 2
chr6_+_149068464 0.706 ENST00000367463.4
UST
uronyl-2-sulfotransferase
chr12_+_56473628 0.703 ENST00000549282.1
ENST00000549061.1
ENST00000267101.3
ERBB3


v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3


chr8_-_144691718 0.660 ENST00000377579.3
ENST00000433751.1
ENST00000220966.6
PYCRL


pyrroline-5-carboxylate reductase-like


chr1_-_40367668 0.653 ENST00000397332.2
ENST00000429311.1
MYCL

v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog

chrX_+_150151752 0.647 ENST00000325307.7
HMGB3
high mobility group box 3
chr8_-_29120580 0.641 ENST00000524189.1
KIF13B
kinesin family member 13B
chr7_+_73442422 0.639 ENST00000358929.4
ENST00000431562.1
ENST00000320492.7
ENST00000438906.1
ELN



elastin



chr17_-_72968809 0.631 ENST00000530857.1
ENST00000425042.2
HID1

HID1 domain containing

chr16_+_23847267 0.628 ENST00000321728.7
PRKCB
protein kinase C, beta
chr11_+_6411670 0.627 ENST00000530395.1
ENST00000527275.1
SMPD1

sphingomyelin phosphodiesterase 1, acid lysosomal

chr11_-_33891362 0.619 ENST00000395833.3
LMO2
LIM domain only 2 (rhombotin-like 1)
chr1_-_226129083 0.613 ENST00000420304.2
LEFTY2
left-right determination factor 2
chr17_+_76165213 0.613 ENST00000590201.1
SYNGR2
synaptogyrin 2
chr11_+_6411636 0.608 ENST00000299397.3
ENST00000356761.2
ENST00000342245.4
SMPD1


sphingomyelin phosphodiesterase 1, acid lysosomal


chr1_-_226129189 0.603 ENST00000366820.5
LEFTY2
left-right determination factor 2
chr9_-_80263220 0.597 ENST00000341700.6
GNA14
guanine nucleotide binding protein (G protein), alpha 14
chr2_+_95537170 0.590 ENST00000295201.4
TEKT4
tektin 4
chr11_+_45918092 0.575 ENST00000395629.2
MAPK8IP1
mitogen-activated protein kinase 8 interacting protein 1
chr6_+_17281573 0.572 ENST00000379052.5
RBM24
RNA binding motif protein 24
chr11_-_108464465 0.564 ENST00000525344.1
EXPH5
exophilin 5
chr1_-_223537475 0.564 ENST00000344029.6
ENST00000494793.2
ENST00000366878.4
ENST00000366877.3
SUSD4



sushi domain containing 4



chr17_-_39280419 0.561 ENST00000394014.1
KRTAP4-12
keratin associated protein 4-12
chr7_+_73442102 0.539 ENST00000445912.1
ENST00000252034.7
ELN

elastin

chr12_+_108525517 0.529 ENST00000332082.4
WSCD2
WSC domain containing 2
chr11_+_86511569 0.524 ENST00000441050.1
PRSS23
protease, serine, 23
chr1_-_223537401 0.518 ENST00000343846.3
ENST00000454695.2
ENST00000484758.2
SUSD4


sushi domain containing 4


chr18_-_54305658 0.515 ENST00000586262.1
ENST00000217515.6
TXNL1

thioredoxin-like 1

chr2_+_121103706 0.506 ENST00000295228.3
INHBB
inhibin, beta B
chr5_+_50678921 0.498 ENST00000230658.7
ISL1
ISL LIM homeobox 1
chr17_-_7216939 0.494 ENST00000573684.1
GPS2
G protein pathway suppressor 2
chr1_-_57285038 0.486 ENST00000343433.6
C1orf168
chromosome 1 open reading frame 168
chr1_+_3614591 0.481 ENST00000378290.4
TP73
tumor protein p73
chr11_-_108464321 0.481 ENST00000265843.4
EXPH5
exophilin 5
chr12_+_122150646 0.471 ENST00000449592.2
TMEM120B
transmembrane protein 120B
chr8_-_121824374 0.461 ENST00000517992.1
SNTB1
syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
chr15_+_97326659 0.457 ENST00000558553.1
SPATA8
spermatogenesis associated 8
chr1_+_159750720 0.456 ENST00000368109.1
ENST00000368108.3
DUSP23

dual specificity phosphatase 23

chr4_+_113970772 0.455 ENST00000504454.1
ENST00000394537.3
ENST00000357077.4
ENST00000264366.6
ANK2



ankyrin 2, neuronal



chr1_+_159750776 0.453 ENST00000368107.1
DUSP23
dual specificity phosphatase 23
chr9_+_136399929 0.451 ENST00000393060.1
ADAMTSL2
ADAMTS-like 2
chr17_+_76164639 0.450 ENST00000225777.3
ENST00000585591.1
ENST00000589711.1
ENST00000588282.1
ENST00000589168.1
SYNGR2




synaptogyrin 2




chr15_-_42186248 0.450 ENST00000320955.6
SPTBN5
spectrin, beta, non-erythrocytic 5
chr2_+_233562015 0.448 ENST00000427233.1
ENST00000373566.3
ENST00000373563.4
ENST00000428883.1
ENST00000456491.1
ENST00000409480.1
ENST00000421433.1
ENST00000425040.1
ENST00000430720.1
ENST00000409547.1
ENST00000423659.1
ENST00000409196.3
ENST00000409451.3
ENST00000429187.1
ENST00000440945.1
GIGYF2














GRB10 interacting GYF protein 2














chr7_+_73442457 0.446 ENST00000438880.1
ENST00000414324.1
ENST00000380562.4
ELN


elastin


chr16_+_88772866 0.446 ENST00000453996.2
ENST00000312060.5
ENST00000378384.3
ENST00000567949.1
ENST00000564921.1
CTU2




cytosolic thiouridylase subunit 2 homolog (S. pombe)




chr11_-_73694346 0.442 ENST00000310473.3
UCP2
uncoupling protein 2 (mitochondrial, proton carrier)
chr5_+_102201687 0.440 ENST00000304400.7
PAM
peptidylglycine alpha-amidating monooxygenase
chr4_+_129732467 0.440 ENST00000413543.2
PHF17
jade family PHD finger 1
chr3_-_121740969 0.437 ENST00000393631.1
ENST00000273691.3
ENST00000344209.5
ILDR1


immunoglobulin-like domain containing receptor 1


chr10_+_11060004 0.434 ENST00000542579.1
ENST00000399850.3
ENST00000417956.2
CELF2


CUGBP, Elav-like family member 2


chr14_+_62584197 0.432 ENST00000334389.4
LINC00643
long intergenic non-protein coding RNA 643
chr5_+_131630117 0.431 ENST00000200652.3
SLC22A4
solute carrier family 22 (organic cation/zwitterion transporter), member 4
chr4_+_89299885 0.425 ENST00000380265.5
ENST00000273960.3
HERC6

HECT and RLD domain containing E3 ubiquitin protein ligase family member 6

chr6_+_133562472 0.420 ENST00000430974.2
ENST00000367895.5
ENST00000355167.3
ENST00000355286.6
EYA4



eyes absent homolog 4 (Drosophila)



chr8_-_130951940 0.418 ENST00000522250.1
ENST00000522941.1
ENST00000522746.1
ENST00000520204.1
ENST00000519070.1
ENST00000520254.1
ENST00000519824.2
ENST00000519540.1
FAM49B







family with sequence similarity 49, member B







chr5_+_139027877 0.415 ENST00000302517.3
CXXC5
CXXC finger protein 5
chrX_+_150151824 0.412 ENST00000455596.1
ENST00000448905.2
HMGB3

high mobility group box 3

chr16_-_31076332 0.412 ENST00000539836.3
ENST00000535577.1
ENST00000442862.2
ZNF668


zinc finger protein 668


chr2_+_24714729 0.410 ENST00000406961.1
ENST00000405141.1
NCOA1

nuclear receptor coactivator 1

chrX_+_115567767 0.409 ENST00000371900.4
SLC6A14
solute carrier family 6 (amino acid transporter), member 14
chr5_+_102201722 0.402 ENST00000274392.9
ENST00000455264.2
PAM

peptidylglycine alpha-amidating monooxygenase

chr1_-_204329013 0.399 ENST00000272203.3
ENST00000414478.1
PLEKHA6

pleckstrin homology domain containing, family A member 6

chr14_-_100625932 0.397 ENST00000553834.1
DEGS2
delta(4)-desaturase, sphingolipid 2
chr2_-_220436248 0.395 ENST00000265318.4
OBSL1
obscurin-like 1
chr4_+_89299994 0.390 ENST00000264346.7
HERC6
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
chr17_-_47755436 0.385 ENST00000505581.1
ENST00000514121.1
ENST00000393328.2
ENST00000509079.1
ENST00000393331.3
ENST00000347630.2
ENST00000504102.1
SPOP






speckle-type POZ protein






chr5_+_169532896 0.382 ENST00000306268.6
ENST00000449804.2
FOXI1

forkhead box I1

chr7_-_150675372 0.382 ENST00000262186.5
KCNH2
potassium voltage-gated channel, subfamily H (eag-related), member 2
chr11_-_88070920 0.381 ENST00000524463.1
ENST00000227266.5
CTSC

cathepsin C

chr1_-_75139397 0.381 ENST00000326665.5
C1orf173
chromosome 1 open reading frame 173
chr17_-_43339474 0.381 ENST00000331780.4
SPATA32
spermatogenesis associated 32
chr14_+_22739823 0.381 ENST00000390464.2
TRAV38-1
T cell receptor alpha variable 38-1
chr7_+_116660246 0.380 ENST00000434836.1
ENST00000393443.1
ENST00000465133.1
ENST00000477742.1
ENST00000393447.4
ENST00000393444.3
ST7





suppression of tumorigenicity 7





chr8_-_17270809 0.380 ENST00000180173.5
ENST00000521857.1
MTMR7

myotubularin related protein 7

chr17_-_43339453 0.375 ENST00000543122.1
SPATA32
spermatogenesis associated 32
chr1_+_61869748 0.371 ENST00000357977.5
NFIA
nuclear factor I/A
chr6_+_44184653 0.370 ENST00000573382.2
ENST00000576476.1
RP1-302G2.5

RP1-302G2.5

chr11_-_47470703 0.369 ENST00000298854.2
RAPSN
receptor-associated protein of the synapse
chr5_+_102201509 0.366 ENST00000348126.2
ENST00000379787.4
PAM

peptidylglycine alpha-amidating monooxygenase

chr16_+_58059470 0.363 ENST00000219271.3
MMP15
matrix metallopeptidase 15 (membrane-inserted)
chr14_-_24911448 0.362 ENST00000555355.1
ENST00000553343.1
ENST00000556523.1
ENST00000556249.1
ENST00000538105.2
ENST00000555225.1
SDR39U1





short chain dehydrogenase/reductase family 39U, member 1





chr8_-_91657740 0.362 ENST00000422900.1
TMEM64
transmembrane protein 64
chr16_+_71660079 0.358 ENST00000565261.1
ENST00000268485.3
ENST00000299952.4
MARVELD3


MARVEL domain containing 3


chr11_+_71938925 0.358 ENST00000538751.1
INPPL1
inositol polyphosphate phosphatase-like 1
chr7_+_150065278 0.358 ENST00000519397.1
ENST00000479668.1
ENST00000540729.1
REPIN1


replication initiator 1


chr8_+_81398444 0.356 ENST00000455036.3
ENST00000426744.2
ZBTB10

zinc finger and BTB domain containing 10

chr16_-_31076273 0.354 ENST00000426488.2
ZNF668
zinc finger protein 668
chr17_+_26369865 0.352 ENST00000582037.1
NLK
nemo-like kinase
chr1_-_33647267 0.351 ENST00000291416.5
TRIM62
tripartite motif containing 62
chr17_+_33474860 0.350 ENST00000394570.2
UNC45B
unc-45 homolog B (C. elegans)
chr5_+_139028510 0.350 ENST00000502336.1
ENST00000520967.1
ENST00000511048.1
CXXC5


CXXC finger protein 5


chr17_+_33474826 0.349 ENST00000268876.5
ENST00000433649.1
ENST00000378449.1
UNC45B


unc-45 homolog B (C. elegans)


chr7_+_35756186 0.348 ENST00000430518.1
AC018647.3
AC018647.3
chrX_-_99986494 0.347 ENST00000372989.1
ENST00000455616.1
ENST00000454200.2
ENST00000276141.6
SYTL4



synaptotagmin-like 4



chr1_+_36023370 0.347 ENST00000356090.4
ENST00000373243.2
NCDN

neurochondrin

chr5_+_102201430 0.346 ENST00000438793.3
ENST00000346918.2
PAM

peptidylglycine alpha-amidating monooxygenase

chr1_-_167905225 0.346 ENST00000367846.4
MPC2
mitochondrial pyruvate carrier 2
chr8_+_67341239 0.346 ENST00000320270.2
RRS1
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
chr11_-_47470591 0.343 ENST00000524487.1
RAPSN
receptor-associated protein of the synapse
chr21_-_34185944 0.343 ENST00000479548.1
C21orf62
chromosome 21 open reading frame 62
chr11_-_2292182 0.336 ENST00000331289.4
ASCL2
achaete-scute family bHLH transcription factor 2
chr17_-_42277203 0.336 ENST00000587097.1
ATXN7L3
ataxin 7-like 3
chr11_-_8954491 0.335 ENST00000526227.1
ENST00000525780.1
ENST00000326053.5
C11orf16


chromosome 11 open reading frame 16


chr17_+_4981535 0.334 ENST00000318833.3
ZFP3
ZFP3 zinc finger protein
chrX_-_102565932 0.334 ENST00000372674.1
ENST00000372677.3
BEX2

brain expressed X-linked 2

chr11_-_67275542 0.332 ENST00000531506.1
CDK2AP2
cyclin-dependent kinase 2 associated protein 2
chr14_-_55369525 0.331 ENST00000543643.2
ENST00000536224.2
ENST00000395514.1
ENST00000491895.2
GCH1



GTP cyclohydrolase 1



chr17_+_40985407 0.327 ENST00000586114.1
ENST00000590720.1
ENST00000585805.1
ENST00000541124.1
ENST00000441946.2
ENST00000591152.1
ENST00000589469.1
ENST00000293362.3
ENST00000592169.1
PSME3








proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)








chr16_-_88772761 0.327 ENST00000567844.1
ENST00000312838.4
RNF166

ring finger protein 166

chr14_-_24912047 0.326 ENST00000553930.1
SDR39U1
short chain dehydrogenase/reductase family 39U, member 1
chr22_+_17082732 0.322 ENST00000558085.2
ENST00000592918.1
ENST00000400593.2
ENST00000592107.1
ENST00000426585.1
ENST00000591299.1
TPTEP1





transmembrane phosphatase with tensin homology pseudogene 1





chr11_+_10476851 0.322 ENST00000396553.2
AMPD3
adenosine monophosphate deaminase 3
chr16_-_103572 0.320 ENST00000293860.5
POLR3K
polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa
chr3_+_32147997 0.319 ENST00000282541.5
GPD1L
glycerol-3-phosphate dehydrogenase 1-like
chr18_-_53089723 0.317 ENST00000561992.1
ENST00000562512.2
TCF4

transcription factor 4

chr17_-_56032602 0.317 ENST00000577840.1
CUEDC1
CUE domain containing 1
chr8_+_81397876 0.317 ENST00000430430.1
ZBTB10
zinc finger and BTB domain containing 10
chr19_+_3094398 0.314 ENST00000078429.4
GNA11
guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
chr12_-_117628253 0.311 ENST00000330622.5
FBXO21
F-box protein 21
chr1_+_16062820 0.308 ENST00000294454.5
SLC25A34
solute carrier family 25, member 34
chr8_-_91657909 0.307 ENST00000418210.2
TMEM64
transmembrane protein 64
chr8_-_72268968 0.306 ENST00000388740.3
EYA1
eyes absent homolog 1 (Drosophila)
chr17_-_39316983 0.305 ENST00000390661.3
KRTAP4-4
keratin associated protein 4-4
chr3_+_108308513 0.304 ENST00000361582.3
DZIP3
DAZ interacting zinc finger protein 3
chr1_-_185286461 0.303 ENST00000367498.3
IVNS1ABP
influenza virus NS1A binding protein
chr16_-_12009735 0.302 ENST00000439887.2
ENST00000434724.2
GSPT1

G1 to S phase transition 1

chr9_-_128003606 0.301 ENST00000324460.6
HSPA5
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
chr3_-_65583561 0.301 ENST00000460329.2
MAGI1
membrane associated guanylate kinase, WW and PDZ domain containing 1
chr22_+_45680822 0.299 ENST00000216211.4
ENST00000396082.2
UPK3A

uroplakin 3A

chr17_-_71088797 0.297 ENST00000580557.1
ENST00000579732.1
ENST00000578620.1
ENST00000542342.2
ENST00000255559.3
ENST00000579018.1
SLC39A11





solute carrier family 39, member 11





chr1_+_40839369 0.291 ENST00000372718.3
SMAP2
small ArfGAP2
chr10_+_123923205 0.290 ENST00000369004.3
ENST00000260733.3
TACC2

transforming, acidic coiled-coil containing protein 2

chr6_+_138483058 0.289 ENST00000251691.4
KIAA1244
KIAA1244
chr12_+_66582919 0.286 ENST00000545837.1
ENST00000457197.2
IRAK3

interleukin-1 receptor-associated kinase 3

chr2_-_37899323 0.282 ENST00000295324.3
ENST00000457889.1
CDC42EP3

CDC42 effector protein (Rho GTPase binding) 3

chr10_+_123922941 0.282 ENST00000360561.3
TACC2
transforming, acidic coiled-coil containing protein 2
chr17_-_39334460 0.279 ENST00000377726.2
KRTAP4-2
keratin associated protein 4-2
chr19_+_14544099 0.278 ENST00000242783.6
ENST00000586557.1
ENST00000590097.1
PKN1


protein kinase N1


chr8_-_139926236 0.277 ENST00000303045.6
ENST00000435777.1
COL22A1

collagen, type XXII, alpha 1

chr3_-_49851313 0.276 ENST00000333486.3
UBA7
ubiquitin-like modifier activating enzyme 7
chr5_-_73937244 0.276 ENST00000302351.4
ENST00000510316.1
ENST00000508331.1
ENC1


ectodermal-neural cortex 1 (with BTB domain)


chr12_-_56122426 0.274 ENST00000551173.1
CD63
CD63 molecule
chr11_+_71238313 0.274 ENST00000398536.4
KRTAP5-7
keratin associated protein 5-7
chr20_-_44455976 0.272 ENST00000372555.3
TNNC2
troponin C type 2 (fast)
chr16_+_71660052 0.271 ENST00000567566.1
MARVELD3
MARVEL domain containing 3
chr10_+_104535994 0.269 ENST00000369889.4
WBP1L
WW domain binding protein 1-like
chr16_-_88772670 0.264 ENST00000562544.1
RNF166
ring finger protein 166
chr17_-_77925806 0.263 ENST00000574241.2
TBC1D16
TBC1 domain family, member 16
chr10_+_89264625 0.263 ENST00000371996.4
ENST00000371994.4
MINPP1

multiple inositol-polyphosphate phosphatase 1

chr4_-_157892498 0.262 ENST00000502773.1
PDGFC
platelet derived growth factor C
chr8_-_72268889 0.261 ENST00000388742.4
EYA1
eyes absent homolog 1 (Drosophila)
chr1_-_86043921 0.257 ENST00000535924.2
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr10_+_123923105 0.255 ENST00000368999.1
TACC2
transforming, acidic coiled-coil containing protein 2
chr3_-_39234074 0.254 ENST00000340369.3
ENST00000421646.1
ENST00000396251.1
XIRP1


xin actin-binding repeat containing 1


chr6_-_45983581 0.253 ENST00000339561.6
CLIC5
chloride intracellular channel 5
chr2_-_227050079 0.252 ENST00000423838.1
AC068138.1
AC068138.1
chr4_-_157892167 0.252 ENST00000541126.1
PDGFC
platelet derived growth factor C

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.4 1.6 GO:0018032 protein amidation(GO:0018032)
0.4 4.2 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.3 1.0 GO:1900073 regulation of neuromuscular synaptic transmission(GO:1900073) positive regulation of neuromuscular synaptic transmission(GO:1900075)
0.3 1.3 GO:0015670 carbon dioxide transport(GO:0015670)
0.2 0.7 GO:1901860 positive regulation of mitochondrial DNA metabolic process(GO:1901860)
0.2 0.5 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143)
0.2 1.2 GO:0023021 termination of signal transduction(GO:0023021)
0.2 0.5 GO:0060279 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.2 0.5 GO:0021524 visceral motor neuron differentiation(GO:0021524) peripheral nervous system neuron axonogenesis(GO:0048936) cardiac cell fate determination(GO:0060913)
0.2 0.5 GO:0035408 histone H3-T6 phosphorylation(GO:0035408)
0.2 0.5 GO:0036309 protein localization to M-band(GO:0036309)
0.2 0.8 GO:2001293 fatty-acyl-CoA catabolic process(GO:0036115) malonyl-CoA metabolic process(GO:2001293)
0.1 0.4 GO:0021966 corticospinal neuron axon guidance(GO:0021966)
0.1 0.4 GO:0045925 positive regulation of female receptivity(GO:0045925)
0.1 1.9 GO:0036159 inner dynein arm assembly(GO:0036159)
0.1 0.4 GO:0006667 sphinganine metabolic process(GO:0006667)
0.1 1.2 GO:0015705 iodide transport(GO:0015705)
0.1 0.4 GO:1902303 regulation of heart rate by hormone(GO:0003064) negative regulation of potassium ion export(GO:1902303)
0.1 1.0 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.1 0.3 GO:0002514 B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663)
0.1 0.2 GO:0001994 norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994)
0.1 0.3 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.1 1.9 GO:0003084 positive regulation of systemic arterial blood pressure(GO:0003084)
0.1 0.7 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.1 0.3 GO:0051066 dihydrobiopterin metabolic process(GO:0051066)
0.1 0.7 GO:0019236 response to pheromone(GO:0019236)
0.1 0.3 GO:0021577 hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589)
0.1 0.4 GO:0090299 regulation of neural crest formation(GO:0090299) negative regulation of neural crest formation(GO:0090301) negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
0.1 0.8 GO:0045607 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.1 0.6 GO:0048388 endosomal lumen acidification(GO:0048388)
0.1 0.3 GO:1901899 positive regulation of relaxation of cardiac muscle(GO:1901899) regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081)
0.1 0.3 GO:1902361 mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
0.1 2.0 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.1 0.3 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.1 0.9 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.1 0.5 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.1 0.9 GO:0042659 regulation of cell fate specification(GO:0042659)
0.1 0.4 GO:2000035 regulation of stem cell division(GO:2000035)
0.1 0.4 GO:0072138 mesenchymal cell proliferation involved in ureteric bud development(GO:0072138)
0.1 0.6 GO:0007258 JUN phosphorylation(GO:0007258)
0.1 0.3 GO:0045872 positive regulation of rhodopsin gene expression(GO:0045872)
0.1 0.6 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.1 1.2 GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.1 0.7 GO:0034311 sphingosine metabolic process(GO:0006670) diol metabolic process(GO:0034311)
0.1 0.7 GO:0006477 protein sulfation(GO:0006477)
0.1 1.4 GO:0051255 spindle midzone assembly(GO:0051255)
0.1 0.4 GO:2000568 memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
0.1 0.1 GO:0072053 renal inner medulla development(GO:0072053) renal outer medulla development(GO:0072054)
0.1 0.3 GO:0051697 protein delipidation(GO:0051697)
0.1 0.2 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.1 0.2 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.1 1.0 GO:0016576 histone dephosphorylation(GO:0016576)
0.1 0.4 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.1 0.2 GO:0032289 central nervous system myelin formation(GO:0032289)
0.1 0.2 GO:0034553 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.1 0.2 GO:0021793 chemorepulsion of branchiomotor axon(GO:0021793)
0.1 0.4 GO:0033183 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.1 0.5 GO:0060481 lobar bronchus epithelium development(GO:0060481) lobar bronchus development(GO:0060482)
0.1 0.2 GO:0072658 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 0.3 GO:0006196 AMP catabolic process(GO:0006196)
0.1 1.2 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.1 0.1 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.1 1.6 GO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway(GO:0010804)
0.0 0.7 GO:1902414 protein localization to cell junction(GO:1902414)
0.0 0.1 GO:1904247 positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
0.0 0.3 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.0 0.2 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.0 0.1 GO:1903517 regulation of telomere maintenance via recombination(GO:0032207) negative regulation of telomere maintenance via recombination(GO:0032208) negative regulation of single strand break repair(GO:1903517) negative regulation of beta-galactosidase activity(GO:1903770) telomere single strand break repair(GO:1903823) negative regulation of telomere single strand break repair(GO:1903824)
0.0 0.3 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.0 0.5 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.2 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.3 GO:0060157 urinary bladder development(GO:0060157)
0.0 0.5 GO:1902570 protein localization to nucleolus(GO:1902570)
0.0 1.4 GO:0010842 retina layer formation(GO:0010842)
0.0 0.2 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0 0.1 GO:0002752 cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.0 0.6 GO:0060294 cilium movement involved in cell motility(GO:0060294)
0.0 0.6 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.1 GO:0001922 B-1 B cell homeostasis(GO:0001922)
0.0 0.7 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.1 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.0 0.2 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.0 2.9 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 0.2 GO:0033490 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.0 0.1 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.0 0.4 GO:0048194 Golgi vesicle budding(GO:0048194)
0.0 0.4 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0 0.8 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 0.1 GO:0060721 spongiotrophoblast cell proliferation(GO:0060720) regulation of spongiotrophoblast cell proliferation(GO:0060721) cell proliferation involved in embryonic placenta development(GO:0060722) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.0 0.1 GO:1903413 cellular response to bile acid(GO:1903413)
0.0 0.2 GO:0015891 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.0 0.1 GO:0019566 arabinose metabolic process(GO:0019566) L-arabinose metabolic process(GO:0046373)
0.0 0.2 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.4 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 0.2 GO:0035511 oxidative DNA demethylation(GO:0035511)
0.0 0.4 GO:0045475 locomotor rhythm(GO:0045475)
0.0 0.4 GO:0035826 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.0 0.3 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.3 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.1 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0 0.4 GO:0046855 inositol phosphate dephosphorylation(GO:0046855)
0.0 0.2 GO:0061052 negative regulation of cell growth involved in cardiac muscle cell development(GO:0061052) dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0 2.4 GO:0007585 respiratory gaseous exchange(GO:0007585)
0.0 0.1 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.0 0.1 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.5 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0 0.1 GO:0003344 pericardium morphogenesis(GO:0003344)
0.0 0.7 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0 1.3 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 0.5 GO:0035988 chondrocyte proliferation(GO:0035988)
0.0 0.1 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.1 GO:1900151 regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)
0.0 0.4 GO:1901750 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.0 0.2 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.1 GO:0001306 age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571)
0.0 0.1 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 0.3 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.7 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.0 0.4 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.0 0.1 GO:0032765 positive regulation of mast cell cytokine production(GO:0032765)
0.0 0.0 GO:0035283 rhombomere 5 development(GO:0021571) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0 0.3 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.4 GO:0007346 regulation of mitotic cell cycle(GO:0007346)
0.0 0.2 GO:0019317 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0 0.6 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.1 GO:0060897 neural plate anterior/posterior regionalization(GO:0021999) neural plate regionalization(GO:0060897)
0.0 0.2 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.0 0.2 GO:0006600 creatine metabolic process(GO:0006600)
0.0 0.2 GO:0071421 manganese ion transmembrane transport(GO:0071421)
0.0 0.1 GO:0001893 maternal placenta development(GO:0001893)
0.0 0.7 GO:0045022 early endosome to late endosome transport(GO:0045022)
0.0 0.1 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
0.0 0.2 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.0 0.3 GO:1900038 negative regulation of cellular response to hypoxia(GO:1900038)
0.0 0.1 GO:1904404 cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
0.0 0.4 GO:0072189 ureter development(GO:0072189)
0.0 0.1 GO:0061009 common bile duct development(GO:0061009)
0.0 0.5 GO:0046329 negative regulation of JNK cascade(GO:0046329)
0.0 1.0 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.0 0.1 GO:0010286 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.0 0.1 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.0 GO:0051461 positive regulation of corticotropin secretion(GO:0051461)
0.0 0.3 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.0 0.0 GO:1903998 regulation of eating behavior(GO:1903998)
0.0 0.4 GO:0032897 negative regulation of viral transcription(GO:0032897)
0.0 0.1 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.0 0.3 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.1 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.0 0.1 GO:0010666 positive regulation of striated muscle cell apoptotic process(GO:0010663) positive regulation of cardiac muscle cell apoptotic process(GO:0010666)
0.0 0.1 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582)
0.0 0.6 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.0 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.2 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0 0.3 GO:1902603 carnitine transmembrane transport(GO:1902603)
0.0 0.9 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.4 GO:0042501 serine phosphorylation of STAT protein(GO:0042501)
0.0 0.1 GO:0006261 DNA-dependent DNA replication(GO:0006261)
0.0 0.5 GO:0048009 insulin-like growth factor receptor signaling pathway(GO:0048009)
0.0 0.1 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.2 GO:0030575 nuclear body organization(GO:0030575)
0.0 0.2 GO:0010763 positive regulation of fibroblast migration(GO:0010763)
0.0 1.3 GO:0032392 DNA geometric change(GO:0032392)
0.0 0.1 GO:0014824 artery smooth muscle contraction(GO:0014824)
0.0 0.1 GO:2000304 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.0 0.1 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.0 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.1 GO:0097427 microtubule bundle(GO:0097427)
0.3 0.9 GO:0005667 transcription factor complex(GO:0005667)
0.2 2.4 GO:0071953 elastic fiber(GO:0071953)
0.2 1.3 GO:1990393 3M complex(GO:1990393)
0.1 0.6 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.1 0.9 GO:0070695 FHF complex(GO:0070695)
0.1 0.3 GO:0018444 translation release factor complex(GO:0018444)
0.1 0.4 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.1 0.6 GO:0044294 dendritic growth cone(GO:0044294)
0.1 1.0 GO:0099634 postsynaptic specialization membrane(GO:0099634)
0.1 0.4 GO:1990635 proximal dendrite(GO:1990635)
0.1 0.3 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.1 0.3 GO:0008537 proteasome activator complex(GO:0008537)
0.1 0.2 GO:0070081 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.0 1.2 GO:0042599 lamellar body(GO:0042599)
0.0 1.6 GO:0051233 spindle midzone(GO:0051233)
0.0 0.3 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836)
0.0 2.2 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.2 GO:0044326 dendritic spine neck(GO:0044326)
0.0 0.3 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 1.2 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.1 GO:0031379 RNA-directed RNA polymerase complex(GO:0031379)
0.0 0.8 GO:0034706 sodium channel complex(GO:0034706)
0.0 0.6 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.1 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.3 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.7 GO:0097440 apical dendrite(GO:0097440)
0.0 0.5 GO:0008091 spectrin(GO:0008091)
0.0 0.4 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.0 1.5 GO:0009925 basal plasma membrane(GO:0009925)
0.0 1.6 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.1 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0 0.4 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.8 GO:0000145 exocyst(GO:0000145)
0.0 0.4 GO:0005833 hemoglobin complex(GO:0005833)
0.0 0.2 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.1 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 0.1 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.3 GO:0000124 SAGA complex(GO:0000124)
0.0 1.5 GO:0031526 brush border membrane(GO:0031526)
0.0 0.2 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.3 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.4 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.1 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.0 0.1 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.2 GO:0031941 filamentous actin(GO:0031941)
0.0 0.5 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.0 GO:0043291 RAVE complex(GO:0043291)
0.0 0.0 GO:0016935 glycine-gated chloride channel complex(GO:0016935)
0.0 0.4 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.2 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.4 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 1.9 GO:0043204 perikaryon(GO:0043204)
0.0 0.1 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0 0.2 GO:0000780 condensed nuclear chromosome, centromeric region(GO:0000780)
0.0 0.1 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.1 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 1.1 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.3 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0 1.6 GO:0005923 bicellular tight junction(GO:0005923)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 4.2 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.6 1.9 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.4 1.6 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.2 1.2 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.2 0.8 GO:0052836 inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.2 0.5 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
0.1 0.4 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.1 0.4 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.1 2.2 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.1 0.4 GO:0008513 secondary active organic cation transmembrane transporter activity(GO:0008513)
0.1 1.3 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 0.6 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.1 0.4 GO:0060422 peptidyl-dipeptidase inhibitor activity(GO:0060422)
0.1 0.5 GO:0050436 microfibril binding(GO:0050436)
0.1 0.3 GO:0008969 phosphohistidine phosphatase activity(GO:0008969)
0.1 0.3 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.1 0.2 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.1 1.3 GO:0015250 water channel activity(GO:0015250)
0.1 0.4 GO:0023030 MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
0.1 0.2 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.1 0.2 GO:0035514 DNA demethylase activity(GO:0035514)
0.1 0.2 GO:0070984 SET domain binding(GO:0070984)
0.1 0.4 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.1 0.7 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.1 0.8 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.1 0.2 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.1 1.0 GO:0005344 oxygen transporter activity(GO:0005344)
0.1 0.8 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.1 0.3 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.1 1.2 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.2 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
0.0 0.1 GO:0002134 pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551)
0.0 0.1 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.0 2.9 GO:0070888 E-box binding(GO:0070888)
0.0 0.3 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.0 0.2 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.0 1.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.3 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.3 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.0 0.1 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.0 0.3 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 1.0 GO:0043495 protein anchor(GO:0043495)
0.0 1.4 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.9 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.1 GO:0003968 RNA-directed RNA polymerase activity(GO:0003968)
0.0 0.3 GO:0019238 cyclohydrolase activity(GO:0019238)
0.0 0.5 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.0 0.4 GO:0034485 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.0 0.3 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.2 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.5 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 0.4 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.6 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.1 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.0 0.4 GO:0034452 dynactin binding(GO:0034452)
0.0 0.4 GO:0005024 transforming growth factor beta-activated receptor activity(GO:0005024)
0.0 1.5 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 0.2 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.1 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
0.0 0.8 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.1 GO:0061769 ribosylnicotinamide kinase activity(GO:0050262) ribosylnicotinate kinase activity(GO:0061769)
0.0 1.7 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.8 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.3 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.1 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.4 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 0.9 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.3 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.6 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.2 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.5 GO:0031404 chloride ion binding(GO:0031404)
0.0 0.2 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.3 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 2.3 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.4 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.2 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0 0.2 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.0 0.1 GO:0004515 nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0 0.6 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.1 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.1 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.1 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.0 0.2 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.5 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.1 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 0.5 GO:0016805 dipeptidase activity(GO:0016805)
0.0 1.1 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.1 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.1 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.0 0.4 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.3 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.4 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.3 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.1 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.0 0.2 GO:0003696 satellite DNA binding(GO:0003696) centromeric DNA binding(GO:0019237)
0.0 0.0 GO:0035033 histone deacetylase regulator activity(GO:0035033) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.0 0.3 GO:0030955 potassium ion binding(GO:0030955)
0.0 0.1 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 0.2 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.3 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.3 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.1 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.9 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.7 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.1 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.4 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.1 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.1 GO:0043532 angiostatin binding(GO:0043532)
0.0 0.1 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.0 0.1 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0 0.5 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.2 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.1 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 0.4 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.1 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.6 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.2 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.3 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.2 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.2 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 0.9 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.1 GO:0032183 SUMO binding(GO:0032183)
0.0 0.0 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 PID_THROMBIN_PAR4_PATHWAY PAR4-mediated thrombin signaling events
0.0 0.7 PID_TCR_JNK_PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 1.2 PID_TRAIL_PATHWAY TRAIL signaling pathway
0.0 0.7 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.0 0.7 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.0 0.1 PID_TCR_RAS_PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.2 PID_FGF_PATHWAY FGF signaling pathway
0.0 0.4 PID_ERB_GENOMIC_PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.2 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.0 0.3 PID_P38_GAMMA_DELTA_PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.7 PID_ECADHERIN_STABILIZATION_PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.7 PID_ARF6_PATHWAY Arf6 signaling events
0.0 0.3 PID_GLYPICAN_1PATHWAY Glypican 1 network
0.0 0.6 ST_DIFFERENTIATION_PATHWAY_IN_PC12_CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.2 PID_HIF1A_PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 1.0 PID_ERA_GENOMIC_PATHWAY Validated nuclear estrogen receptor alpha network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 0.9 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 2.5 REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.8 REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 1.2 REACTOME_SIGNALING_BY_NODAL Genes involved in Signaling by NODAL
0.0 1.2 REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.5 REACTOME_GLYCOPROTEIN_HORMONES Genes involved in Glycoprotein hormones
0.0 0.4 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_LATE_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 1.1 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.6 REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.5 REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 1.5 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.0 1.3 REACTOME_SPHINGOLIPID_METABOLISM Genes involved in Sphingolipid metabolism
0.0 0.3 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.4 REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.6 REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.1 REACTOME_P130CAS_LINKAGE_TO_MAPK_SIGNALING_FOR_INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 1.1 REACTOME_CHONDROITIN_SULFATE_DERMATAN_SULFATE_METABOLISM Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0 0.4 REACTOME_DOWNREGULATION_OF_ERBB2_ERBB3_SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.6 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.0 0.8 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.0 0.3 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.3 REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.2 REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 3.7 REACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.2 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_GOLGI_MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.2 REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.4 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.4 REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX Genes involved in Degradation of the extracellular matrix