Motif ID: MYOD1
Z-value: 0.764
Transcription factors associated with MYOD1:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
MYOD1 | ENSG00000129152.3 | MYOD1 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
MYOD1 | hg19_v2_chr11_+_17741111_17741124 | 0.01 | 9.7e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.6 | 1.8 | GO:0090076 | relaxation of skeletal muscle(GO:0090076) |
0.4 | 1.6 | GO:0018032 | protein amidation(GO:0018032) |
0.4 | 4.2 | GO:0045329 | carnitine biosynthetic process(GO:0045329) |
0.3 | 1.0 | GO:1900073 | regulation of neuromuscular synaptic transmission(GO:1900073) positive regulation of neuromuscular synaptic transmission(GO:1900075) |
0.3 | 1.3 | GO:0015670 | carbon dioxide transport(GO:0015670) |
0.2 | 0.7 | GO:1901860 | positive regulation of mitochondrial DNA metabolic process(GO:1901860) |
0.2 | 0.5 | GO:0002143 | tRNA wobble position uridine thiolation(GO:0002143) |
0.2 | 1.2 | GO:0023021 | termination of signal transduction(GO:0023021) |
0.2 | 0.5 | GO:0060279 | regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279) |
0.2 | 0.5 | GO:0021524 | visceral motor neuron differentiation(GO:0021524) peripheral nervous system neuron axonogenesis(GO:0048936) cardiac cell fate determination(GO:0060913) |
0.2 | 0.5 | GO:0035408 | histone H3-T6 phosphorylation(GO:0035408) |
0.2 | 0.5 | GO:0036309 | protein localization to M-band(GO:0036309) |
0.2 | 0.8 | GO:2001293 | fatty-acyl-CoA catabolic process(GO:0036115) malonyl-CoA metabolic process(GO:2001293) |
0.1 | 0.4 | GO:0021966 | corticospinal neuron axon guidance(GO:0021966) |
0.1 | 0.4 | GO:0045925 | positive regulation of female receptivity(GO:0045925) |
0.1 | 1.9 | GO:0036159 | inner dynein arm assembly(GO:0036159) |
0.1 | 0.4 | GO:0006667 | sphinganine metabolic process(GO:0006667) |
0.1 | 1.2 | GO:0015705 | iodide transport(GO:0015705) |
0.1 | 0.4 | GO:1902303 | regulation of heart rate by hormone(GO:0003064) negative regulation of potassium ion export(GO:1902303) |
0.1 | 1.0 | GO:0043353 | enucleate erythrocyte differentiation(GO:0043353) |
0.1 | 0.3 | GO:0002514 | B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663) |
0.1 | 0.2 | GO:0001994 | norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994) |
0.1 | 0.3 | GO:0002184 | cytoplasmic translational termination(GO:0002184) |
0.1 | 1.9 | GO:0003084 | positive regulation of systemic arterial blood pressure(GO:0003084) |
0.1 | 0.7 | GO:0044339 | canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339) |
0.1 | 0.3 | GO:0051066 | dihydrobiopterin metabolic process(GO:0051066) |
0.1 | 0.7 | GO:0019236 | response to pheromone(GO:0019236) |
0.1 | 0.3 | GO:0021577 | hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589) |
0.1 | 0.4 | GO:0090299 | regulation of neural crest formation(GO:0090299) negative regulation of neural crest formation(GO:0090301) negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314) |
0.1 | 0.8 | GO:0045607 | regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980) |
0.1 | 0.6 | GO:0048388 | endosomal lumen acidification(GO:0048388) |
0.1 | 0.3 | GO:1901899 | positive regulation of relaxation of cardiac muscle(GO:1901899) regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081) |
0.1 | 0.3 | GO:1902361 | mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361) |
0.1 | 2.0 | GO:0045603 | positive regulation of endothelial cell differentiation(GO:0045603) |
0.1 | 0.3 | GO:0060708 | spongiotrophoblast differentiation(GO:0060708) |
0.1 | 0.9 | GO:0060158 | phospholipase C-activating dopamine receptor signaling pathway(GO:0060158) |
0.1 | 0.5 | GO:2000676 | positive regulation of type B pancreatic cell apoptotic process(GO:2000676) |
0.1 | 0.9 | GO:0042659 | regulation of cell fate specification(GO:0042659) |
0.1 | 0.4 | GO:2000035 | regulation of stem cell division(GO:2000035) |
0.1 | 0.4 | GO:0072138 | mesenchymal cell proliferation involved in ureteric bud development(GO:0072138) |
0.1 | 0.6 | GO:0007258 | JUN phosphorylation(GO:0007258) |
0.1 | 0.3 | GO:0045872 | positive regulation of rhodopsin gene expression(GO:0045872) |
0.1 | 0.6 | GO:0072383 | plus-end-directed vesicle transport along microtubule(GO:0072383) |
0.1 | 1.2 | GO:0040037 | negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037) |
0.1 | 0.7 | GO:0034311 | sphingosine metabolic process(GO:0006670) diol metabolic process(GO:0034311) |
0.1 | 0.7 | GO:0006477 | protein sulfation(GO:0006477) |
0.1 | 1.4 | GO:0051255 | spindle midzone assembly(GO:0051255) |
0.1 | 0.4 | GO:2000568 | memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568) |
0.1 | 0.1 | GO:0072053 | renal inner medulla development(GO:0072053) renal outer medulla development(GO:0072054) |
0.1 | 0.3 | GO:0051697 | protein delipidation(GO:0051697) |
0.1 | 0.2 | GO:0070105 | positive regulation of interleukin-6-mediated signaling pathway(GO:0070105) |
0.1 | 0.2 | GO:0002949 | tRNA threonylcarbamoyladenosine modification(GO:0002949) |
0.1 | 1.0 | GO:0016576 | histone dephosphorylation(GO:0016576) |
0.1 | 0.4 | GO:0060373 | regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373) |
0.1 | 0.2 | GO:0032289 | central nervous system myelin formation(GO:0032289) |
0.1 | 0.2 | GO:0034553 | respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032) |
0.1 | 0.2 | GO:0021793 | chemorepulsion of branchiomotor axon(GO:0021793) |
0.1 | 0.4 | GO:0033183 | negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) |
0.1 | 0.5 | GO:0060481 | lobar bronchus epithelium development(GO:0060481) lobar bronchus development(GO:0060482) |
0.1 | 0.2 | GO:0072658 | maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827) |
0.1 | 0.3 | GO:0006196 | AMP catabolic process(GO:0006196) |
0.1 | 1.2 | GO:0071985 | multivesicular body sorting pathway(GO:0071985) |
0.1 | 0.1 | GO:0006452 | translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905) |
0.1 | 1.6 | GO:0010804 | negative regulation of tumor necrosis factor-mediated signaling pathway(GO:0010804) |
0.0 | 0.7 | GO:1902414 | protein localization to cell junction(GO:1902414) |
0.0 | 0.1 | GO:1904247 | positive regulation of polynucleotide adenylyltransferase activity(GO:1904247) |
0.0 | 0.3 | GO:0010936 | negative regulation of macrophage cytokine production(GO:0010936) |
0.0 | 0.2 | GO:0035426 | extracellular matrix-cell signaling(GO:0035426) |
0.0 | 0.1 | GO:1903517 | regulation of telomere maintenance via recombination(GO:0032207) negative regulation of telomere maintenance via recombination(GO:0032208) negative regulation of single strand break repair(GO:1903517) negative regulation of beta-galactosidase activity(GO:1903770) telomere single strand break repair(GO:1903823) negative regulation of telomere single strand break repair(GO:1903824) |
0.0 | 0.3 | GO:0035407 | histone H3-T11 phosphorylation(GO:0035407) |
0.0 | 0.5 | GO:0051611 | negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612) |
0.0 | 0.2 | GO:0007023 | post-chaperonin tubulin folding pathway(GO:0007023) |
0.0 | 0.3 | GO:0060157 | urinary bladder development(GO:0060157) |
0.0 | 0.5 | GO:1902570 | protein localization to nucleolus(GO:1902570) |
0.0 | 1.4 | GO:0010842 | retina layer formation(GO:0010842) |
0.0 | 0.2 | GO:0090070 | positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234) |
0.0 | 0.1 | GO:0002752 | cell surface pattern recognition receptor signaling pathway(GO:0002752) |
0.0 | 0.6 | GO:0060294 | cilium movement involved in cell motility(GO:0060294) |
0.0 | 0.6 | GO:0043508 | negative regulation of JUN kinase activity(GO:0043508) |
0.0 | 0.1 | GO:0001922 | B-1 B cell homeostasis(GO:0001922) |
0.0 | 0.7 | GO:0071688 | striated muscle myosin thick filament assembly(GO:0071688) |
0.0 | 0.1 | GO:1900220 | semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220) |
0.0 | 0.2 | GO:0015842 | aminergic neurotransmitter loading into synaptic vesicle(GO:0015842) |
0.0 | 2.9 | GO:0001578 | microtubule bundle formation(GO:0001578) |
0.0 | 0.2 | GO:0033490 | cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490) |
0.0 | 0.1 | GO:1901675 | negative regulation of histone H3-K27 acetylation(GO:1901675) |
0.0 | 0.4 | GO:0048194 | Golgi vesicle budding(GO:0048194) |
0.0 | 0.4 | GO:0061179 | negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179) |
0.0 | 0.8 | GO:0097067 | cellular response to thyroid hormone stimulus(GO:0097067) |
0.0 | 0.1 | GO:0060721 | spongiotrophoblast cell proliferation(GO:0060720) regulation of spongiotrophoblast cell proliferation(GO:0060721) cell proliferation involved in embryonic placenta development(GO:0060722) regulation of cell proliferation involved in embryonic placenta development(GO:0060723) |
0.0 | 0.1 | GO:1903413 | cellular response to bile acid(GO:1903413) |
0.0 | 0.2 | GO:0015891 | iron chelate transport(GO:0015688) siderophore transport(GO:0015891) |
0.0 | 0.1 | GO:0019566 | arabinose metabolic process(GO:0019566) L-arabinose metabolic process(GO:0046373) |
0.0 | 0.2 | GO:0016554 | cytidine to uridine editing(GO:0016554) |
0.0 | 0.4 | GO:1990573 | potassium ion import across plasma membrane(GO:1990573) |
0.0 | 0.2 | GO:0035511 | oxidative DNA demethylation(GO:0035511) |
0.0 | 0.4 | GO:0045475 | locomotor rhythm(GO:0045475) |
0.0 | 0.4 | GO:0035826 | rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680) |
0.0 | 0.3 | GO:0032020 | ISG15-protein conjugation(GO:0032020) |
0.0 | 0.3 | GO:0010499 | proteasomal ubiquitin-independent protein catabolic process(GO:0010499) |
0.0 | 0.1 | GO:0000379 | tRNA-type intron splice site recognition and cleavage(GO:0000379) |
0.0 | 0.4 | GO:0046855 | inositol phosphate dephosphorylation(GO:0046855) |
0.0 | 0.2 | GO:0061052 | negative regulation of cell growth involved in cardiac muscle cell development(GO:0061052) dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940) |
0.0 | 2.4 | GO:0007585 | respiratory gaseous exchange(GO:0007585) |
0.0 | 0.1 | GO:0001550 | ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165) |
0.0 | 0.1 | GO:0034421 | post-translational protein acetylation(GO:0034421) |
0.0 | 0.5 | GO:0070886 | positive regulation of calcineurin-NFAT signaling cascade(GO:0070886) |
0.0 | 0.1 | GO:0003344 | pericardium morphogenesis(GO:0003344) |
0.0 | 0.7 | GO:0007171 | activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171) |
0.0 | 1.3 | GO:0010862 | positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862) |
0.0 | 0.5 | GO:0035988 | chondrocyte proliferation(GO:0035988) |
0.0 | 0.1 | GO:0070358 | actin polymerization-dependent cell motility(GO:0070358) |
0.0 | 0.1 | GO:1900151 | regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153) |
0.0 | 0.4 | GO:1901750 | leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750) |
0.0 | 0.2 | GO:1901341 | activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341) |
0.0 | 0.1 | GO:0001306 | age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571) |
0.0 | 0.1 | GO:0060040 | retinal bipolar neuron differentiation(GO:0060040) |
0.0 | 0.3 | GO:0031274 | positive regulation of pseudopodium assembly(GO:0031274) |
0.0 | 0.7 | GO:0032958 | inositol phosphate biosynthetic process(GO:0032958) |
0.0 | 0.4 | GO:0019852 | L-ascorbic acid metabolic process(GO:0019852) |
0.0 | 0.1 | GO:0032765 | positive regulation of mast cell cytokine production(GO:0032765) |
0.0 | 0.0 | GO:0035283 | rhombomere 5 development(GO:0021571) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284) |
0.0 | 0.3 | GO:0060088 | auditory receptor cell stereocilium organization(GO:0060088) |
0.0 | 0.4 | GO:0007346 | regulation of mitotic cell cycle(GO:0007346) |
0.0 | 0.2 | GO:0019317 | fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355) |
0.0 | 0.6 | GO:0016338 | calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338) |
0.0 | 0.1 | GO:0060897 | neural plate anterior/posterior regionalization(GO:0021999) neural plate regionalization(GO:0060897) |
0.0 | 0.2 | GO:0010571 | positive regulation of nuclear cell cycle DNA replication(GO:0010571) |
0.0 | 0.2 | GO:0006600 | creatine metabolic process(GO:0006600) |
0.0 | 0.2 | GO:0071421 | manganese ion transmembrane transport(GO:0071421) |
0.0 | 0.1 | GO:0001893 | maternal placenta development(GO:0001893) |
0.0 | 0.7 | GO:0045022 | early endosome to late endosome transport(GO:0045022) |
0.0 | 0.1 | GO:0051083 | 'de novo' cotranslational protein folding(GO:0051083) |
0.0 | 0.2 | GO:0060754 | positive regulation of mast cell chemotaxis(GO:0060754) |
0.0 | 0.3 | GO:1900038 | negative regulation of cellular response to hypoxia(GO:1900038) |
0.0 | 0.1 | GO:1904404 | cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404) |
0.0 | 0.4 | GO:0072189 | ureter development(GO:0072189) |
0.0 | 0.1 | GO:0061009 | common bile duct development(GO:0061009) |
0.0 | 0.5 | GO:0046329 | negative regulation of JNK cascade(GO:0046329) |
0.0 | 1.0 | GO:0043123 | positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123) |
0.0 | 0.1 | GO:0010286 | heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370) |
0.0 | 0.1 | GO:0097428 | protein maturation by iron-sulfur cluster transfer(GO:0097428) |
0.0 | 0.0 | GO:0051461 | positive regulation of corticotropin secretion(GO:0051461) |
0.0 | 0.3 | GO:0007213 | G-protein coupled acetylcholine receptor signaling pathway(GO:0007213) |
0.0 | 0.0 | GO:1903998 | regulation of eating behavior(GO:1903998) |
0.0 | 0.4 | GO:0032897 | negative regulation of viral transcription(GO:0032897) |
0.0 | 0.1 | GO:0006933 | negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933) |
0.0 | 0.3 | GO:0046856 | phosphatidylinositol dephosphorylation(GO:0046856) |
0.0 | 0.1 | GO:0097105 | presynaptic membrane assembly(GO:0097105) |
0.0 | 0.1 | GO:0010666 | positive regulation of striated muscle cell apoptotic process(GO:0010663) positive regulation of cardiac muscle cell apoptotic process(GO:0010666) |
0.0 | 0.1 | GO:0008582 | regulation of synaptic growth at neuromuscular junction(GO:0008582) |
0.0 | 0.6 | GO:0006376 | mRNA splice site selection(GO:0006376) |
0.0 | 0.0 | GO:0045218 | zonula adherens maintenance(GO:0045218) |
0.0 | 0.2 | GO:0035735 | intraciliary transport involved in cilium morphogenesis(GO:0035735) |
0.0 | 0.3 | GO:1902603 | carnitine transmembrane transport(GO:1902603) |
0.0 | 0.9 | GO:0006904 | vesicle docking involved in exocytosis(GO:0006904) |
0.0 | 0.4 | GO:0042501 | serine phosphorylation of STAT protein(GO:0042501) |
0.0 | 0.1 | GO:0006261 | DNA-dependent DNA replication(GO:0006261) |
0.0 | 0.5 | GO:0048009 | insulin-like growth factor receptor signaling pathway(GO:0048009) |
0.0 | 0.1 | GO:0006627 | protein processing involved in protein targeting to mitochondrion(GO:0006627) |
0.0 | 0.2 | GO:0030575 | nuclear body organization(GO:0030575) |
0.0 | 0.2 | GO:0010763 | positive regulation of fibroblast migration(GO:0010763) |
0.0 | 1.3 | GO:0032392 | DNA geometric change(GO:0032392) |
0.0 | 0.1 | GO:0014824 | artery smooth muscle contraction(GO:0014824) |
0.0 | 0.1 | GO:2000304 | positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304) |
0.0 | 0.1 | GO:0043248 | proteasome assembly(GO:0043248) |
0.0 | 0.0 | GO:0035860 | glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 3.1 | GO:0097427 | microtubule bundle(GO:0097427) |
0.3 | 0.9 | GO:0005667 | transcription factor complex(GO:0005667) |
0.2 | 2.4 | GO:0071953 | elastic fiber(GO:0071953) |
0.2 | 1.3 | GO:1990393 | 3M complex(GO:1990393) |
0.1 | 0.6 | GO:0090498 | extrinsic component of Golgi membrane(GO:0090498) |
0.1 | 0.9 | GO:0070695 | FHF complex(GO:0070695) |
0.1 | 0.3 | GO:0018444 | translation release factor complex(GO:0018444) |
0.1 | 0.4 | GO:1902937 | inward rectifier potassium channel complex(GO:1902937) |
0.1 | 0.6 | GO:0044294 | dendritic growth cone(GO:0044294) |
0.1 | 1.0 | GO:0099634 | postsynaptic specialization membrane(GO:0099634) |
0.1 | 0.4 | GO:1990635 | proximal dendrite(GO:1990635) |
0.1 | 0.3 | GO:0009331 | glycerol-3-phosphate dehydrogenase complex(GO:0009331) |
0.1 | 0.3 | GO:0008537 | proteasome activator complex(GO:0008537) |
0.1 | 0.2 | GO:0070081 | clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083) |
0.0 | 1.2 | GO:0042599 | lamellar body(GO:0042599) |
0.0 | 1.6 | GO:0051233 | spindle midzone(GO:0051233) |
0.0 | 0.3 | GO:0000836 | Hrd1p ubiquitin ligase complex(GO:0000836) |
0.0 | 2.2 | GO:0005790 | smooth endoplasmic reticulum(GO:0005790) |
0.0 | 0.2 | GO:0044326 | dendritic spine neck(GO:0044326) |
0.0 | 0.3 | GO:0070022 | transforming growth factor beta receptor homodimeric complex(GO:0070022) |
0.0 | 1.2 | GO:0034451 | centriolar satellite(GO:0034451) |
0.0 | 0.1 | GO:0031379 | RNA-directed RNA polymerase complex(GO:0031379) |
0.0 | 0.8 | GO:0034706 | sodium channel complex(GO:0034706) |
0.0 | 0.6 | GO:0033270 | paranode region of axon(GO:0033270) |
0.0 | 0.1 | GO:0042720 | mitochondrial inner membrane peptidase complex(GO:0042720) |
0.0 | 0.3 | GO:0033018 | sarcoplasmic reticulum lumen(GO:0033018) |
0.0 | 0.7 | GO:0097440 | apical dendrite(GO:0097440) |
0.0 | 0.5 | GO:0008091 | spectrin(GO:0008091) |
0.0 | 0.4 | GO:0097487 | multivesicular body, internal vesicle(GO:0097487) |
0.0 | 1.5 | GO:0009925 | basal plasma membrane(GO:0009925) |
0.0 | 1.6 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
0.0 | 0.1 | GO:1990604 | IRE1-TRAF2-ASK1 complex(GO:1990604) |
0.0 | 0.4 | GO:0005664 | origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664) |
0.0 | 0.8 | GO:0000145 | exocyst(GO:0000145) |
0.0 | 0.4 | GO:0005833 | hemoglobin complex(GO:0005833) |
0.0 | 0.2 | GO:0008385 | IkappaB kinase complex(GO:0008385) |
0.0 | 0.1 | GO:0000214 | tRNA-intron endonuclease complex(GO:0000214) |
0.0 | 0.1 | GO:0030121 | AP-1 adaptor complex(GO:0030121) |
0.0 | 0.3 | GO:0000124 | SAGA complex(GO:0000124) |
0.0 | 1.5 | GO:0031526 | brush border membrane(GO:0031526) |
0.0 | 0.2 | GO:0032541 | cortical endoplasmic reticulum(GO:0032541) |
0.0 | 0.3 | GO:0002116 | semaphorin receptor complex(GO:0002116) |
0.0 | 0.4 | GO:0005890 | sodium:potassium-exchanging ATPase complex(GO:0005890) |
0.0 | 0.1 | GO:0097129 | cyclin D2-CDK4 complex(GO:0097129) |
0.0 | 0.1 | GO:0030870 | Mre11 complex(GO:0030870) |
0.0 | 0.2 | GO:0031941 | filamentous actin(GO:0031941) |
0.0 | 0.5 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
0.0 | 0.0 | GO:0043291 | RAVE complex(GO:0043291) |
0.0 | 0.0 | GO:0016935 | glycine-gated chloride channel complex(GO:0016935) |
0.0 | 0.4 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
0.0 | 0.2 | GO:0044224 | juxtaparanode region of axon(GO:0044224) |
0.0 | 0.4 | GO:0030687 | preribosome, large subunit precursor(GO:0030687) |
0.0 | 1.9 | GO:0043204 | perikaryon(GO:0043204) |
0.0 | 0.1 | GO:0000275 | mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) |
0.0 | 0.2 | GO:0000780 | condensed nuclear chromosome, centromeric region(GO:0000780) |
0.0 | 0.1 | GO:0044295 | axonal growth cone(GO:0044295) |
0.0 | 0.1 | GO:1990712 | HFE-transferrin receptor complex(GO:1990712) |
0.0 | 1.1 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) |
0.0 | 0.3 | GO:0031304 | intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305) |
0.0 | 1.6 | GO:0005923 | bicellular tight junction(GO:0005923) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.1 | 4.2 | GO:0008336 | gamma-butyrobetaine dioxygenase activity(GO:0008336) |
0.6 | 1.9 | GO:0003845 | 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845) |
0.4 | 1.6 | GO:0004504 | peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598) |
0.2 | 1.2 | GO:0015111 | iodide transmembrane transporter activity(GO:0015111) |
0.2 | 0.8 | GO:0052836 | inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839) |
0.2 | 0.5 | GO:0035403 | histone kinase activity (H3-T6 specific)(GO:0035403) |
0.1 | 0.4 | GO:0086062 | voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062) |
0.1 | 0.4 | GO:0070506 | high-density lipoprotein particle receptor activity(GO:0070506) |
0.1 | 2.2 | GO:0086008 | voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008) |
0.1 | 0.4 | GO:0008513 | secondary active organic cation transmembrane transporter activity(GO:0008513) |
0.1 | 1.3 | GO:0004767 | sphingomyelin phosphodiesterase activity(GO:0004767) |
0.1 | 0.6 | GO:0072320 | volume-sensitive chloride channel activity(GO:0072320) |
0.1 | 0.4 | GO:0060422 | peptidyl-dipeptidase inhibitor activity(GO:0060422) |
0.1 | 0.5 | GO:0050436 | microfibril binding(GO:0050436) |
0.1 | 0.3 | GO:0008969 | phosphohistidine phosphatase activity(GO:0008969) |
0.1 | 0.3 | GO:0005026 | transforming growth factor beta receptor activity, type II(GO:0005026) |
0.1 | 0.2 | GO:0004937 | alpha1-adrenergic receptor activity(GO:0004937) |
0.1 | 1.3 | GO:0015250 | water channel activity(GO:0015250) |
0.1 | 0.4 | GO:0023030 | MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030) |
0.1 | 0.2 | GO:0015222 | serotonin transmembrane transporter activity(GO:0015222) |
0.1 | 0.2 | GO:0035514 | DNA demethylase activity(GO:0035514) |
0.1 | 0.2 | GO:0070984 | SET domain binding(GO:0070984) |
0.1 | 0.4 | GO:0017077 | oxidative phosphorylation uncoupler activity(GO:0017077) |
0.1 | 0.7 | GO:0005225 | volume-sensitive anion channel activity(GO:0005225) |
0.1 | 0.8 | GO:0097371 | MDM2/MDM4 family protein binding(GO:0097371) |
0.1 | 0.2 | GO:0003986 | acetyl-CoA hydrolase activity(GO:0003986) |
0.1 | 1.0 | GO:0005344 | oxygen transporter activity(GO:0005344) |
0.1 | 0.8 | GO:0042975 | peroxisome proliferator activated receptor binding(GO:0042975) |
0.1 | 0.3 | GO:0031826 | type 2A serotonin receptor binding(GO:0031826) |
0.1 | 1.2 | GO:0031435 | mitogen-activated protein kinase kinase kinase binding(GO:0031435) |
0.0 | 0.2 | GO:0030899 | calcium-dependent ATPase activity(GO:0030899) |
0.0 | 0.1 | GO:0002134 | pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551) |
0.0 | 0.1 | GO:0010698 | acetyltransferase activator activity(GO:0010698) |
0.0 | 2.9 | GO:0070888 | E-box binding(GO:0070888) |
0.0 | 0.3 | GO:0035402 | histone kinase activity (H3-T11 specific)(GO:0035402) |
0.0 | 0.2 | GO:0018479 | benzaldehyde dehydrogenase (NAD+) activity(GO:0018479) |
0.0 | 1.2 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
0.0 | 0.3 | GO:0004839 | ubiquitin activating enzyme activity(GO:0004839) |
0.0 | 0.3 | GO:0050833 | pyruvate transmembrane transporter activity(GO:0050833) |
0.0 | 0.1 | GO:0016230 | sphingomyelin phosphodiesterase activator activity(GO:0016230) |
0.0 | 0.3 | GO:0003747 | translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079) |
0.0 | 1.0 | GO:0043495 | protein anchor(GO:0043495) |
0.0 | 1.4 | GO:0008301 | DNA binding, bending(GO:0008301) |
0.0 | 0.9 | GO:0005251 | delayed rectifier potassium channel activity(GO:0005251) |
0.0 | 0.1 | GO:0003968 | RNA-directed RNA polymerase activity(GO:0003968) |
0.0 | 0.3 | GO:0019238 | cyclohydrolase activity(GO:0019238) |
0.0 | 0.5 | GO:0047134 | protein-disulfide reductase activity(GO:0047134) |
0.0 | 0.4 | GO:0034485 | phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485) |
0.0 | 0.3 | GO:0008097 | 5S rRNA binding(GO:0008097) |
0.0 | 0.2 | GO:0004430 | 1-phosphatidylinositol 4-kinase activity(GO:0004430) |
0.0 | 0.5 | GO:0016783 | sulfurtransferase activity(GO:0016783) |
0.0 | 0.4 | GO:0004128 | cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128) |
0.0 | 0.6 | GO:0005391 | sodium:potassium-exchanging ATPase activity(GO:0005391) |
0.0 | 0.1 | GO:0046556 | alpha-L-arabinofuranosidase activity(GO:0046556) |
0.0 | 0.4 | GO:0034452 | dynactin binding(GO:0034452) |
0.0 | 0.4 | GO:0005024 | transforming growth factor beta-activated receptor activity(GO:0005024) |
0.0 | 1.5 | GO:0051393 | alpha-actinin binding(GO:0051393) |
0.0 | 0.2 | GO:0043183 | vascular endothelial growth factor receptor 1 binding(GO:0043183) |
0.0 | 0.1 | GO:0005280 | hydrogen:amino acid symporter activity(GO:0005280) |
0.0 | 0.8 | GO:0016922 | ligand-dependent nuclear receptor binding(GO:0016922) |
0.0 | 0.1 | GO:0061769 | ribosylnicotinamide kinase activity(GO:0050262) ribosylnicotinate kinase activity(GO:0061769) |
0.0 | 1.7 | GO:0005160 | transforming growth factor beta receptor binding(GO:0005160) |
0.0 | 0.8 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
0.0 | 0.3 | GO:0052629 | phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629) |
0.0 | 0.1 | GO:0008597 | calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597) |
0.0 | 0.4 | GO:0036374 | glutathione hydrolase activity(GO:0036374) |
0.0 | 0.9 | GO:0051959 | dynein light intermediate chain binding(GO:0051959) |
0.0 | 0.3 | GO:1904264 | ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264) |
0.0 | 0.6 | GO:0071889 | 14-3-3 protein binding(GO:0071889) |
0.0 | 0.2 | GO:0005007 | fibroblast growth factor-activated receptor activity(GO:0005007) |
0.0 | 0.5 | GO:0031404 | chloride ion binding(GO:0031404) |
0.0 | 0.2 | GO:0047623 | AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623) |
0.0 | 0.3 | GO:0015280 | ligand-gated sodium channel activity(GO:0015280) |
0.0 | 2.3 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
0.0 | 0.4 | GO:0034450 | ubiquitin-ubiquitin ligase activity(GO:0034450) |
0.0 | 0.2 | GO:0046920 | alpha-(1->3)-fucosyltransferase activity(GO:0046920) |
0.0 | 0.2 | GO:0005384 | manganese ion transmembrane transporter activity(GO:0005384) |
0.0 | 0.1 | GO:0004515 | nicotinate-nucleotide adenylyltransferase activity(GO:0004515) |
0.0 | 0.6 | GO:0031683 | G-protein beta/gamma-subunit complex binding(GO:0031683) |
0.0 | 0.1 | GO:0004111 | creatine kinase activity(GO:0004111) |
0.0 | 0.1 | GO:0070290 | N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290) |
0.0 | 0.1 | GO:0000213 | tRNA-intron endonuclease activity(GO:0000213) |
0.0 | 0.2 | GO:0008420 | CTD phosphatase activity(GO:0008420) |
0.0 | 0.5 | GO:0005095 | GTPase inhibitor activity(GO:0005095) |
0.0 | 0.1 | GO:0003964 | telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964) |
0.0 | 0.5 | GO:0016805 | dipeptidase activity(GO:0016805) |
0.0 | 1.1 | GO:0008138 | protein tyrosine/serine/threonine phosphatase activity(GO:0008138) |
0.0 | 0.1 | GO:0001594 | trace-amine receptor activity(GO:0001594) |
0.0 | 0.1 | GO:0086006 | voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006) |
0.0 | 0.4 | GO:0005328 | neurotransmitter:sodium symporter activity(GO:0005328) |
0.0 | 0.3 | GO:0017154 | semaphorin receptor activity(GO:0017154) |
0.0 | 0.4 | GO:0004707 | MAP kinase activity(GO:0004707) |
0.0 | 0.3 | GO:0051787 | misfolded protein binding(GO:0051787) |
0.0 | 0.1 | GO:0001165 | RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165) |
0.0 | 0.2 | GO:0003696 | satellite DNA binding(GO:0003696) centromeric DNA binding(GO:0019237) |
0.0 | 0.0 | GO:0035033 | histone deacetylase regulator activity(GO:0035033) corticotropin-releasing hormone receptor 1 binding(GO:0051430) |
0.0 | 0.3 | GO:0030955 | potassium ion binding(GO:0030955) |
0.0 | 0.1 | GO:0022850 | serotonin-gated cation channel activity(GO:0022850) |
0.0 | 0.2 | GO:0097322 | 7SK snRNA binding(GO:0097322) |
0.0 | 0.3 | GO:0043522 | leucine zipper domain binding(GO:0043522) |
0.0 | 0.3 | GO:0017049 | GTP-Rho binding(GO:0017049) |
0.0 | 0.1 | GO:0071933 | Arp2/3 complex binding(GO:0071933) |
0.0 | 0.9 | GO:0016831 | carboxy-lyase activity(GO:0016831) |
0.0 | 0.7 | GO:0051879 | Hsp90 protein binding(GO:0051879) |
0.0 | 0.1 | GO:0004784 | superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721) |
0.0 | 0.4 | GO:0070064 | proline-rich region binding(GO:0070064) |
0.0 | 0.1 | GO:0032051 | clathrin light chain binding(GO:0032051) |
0.0 | 0.1 | GO:0043532 | angiostatin binding(GO:0043532) |
0.0 | 0.1 | GO:0031726 | CCR1 chemokine receptor binding(GO:0031726) |
0.0 | 0.1 | GO:0004118 | cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) |
0.0 | 0.5 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) |
0.0 | 0.2 | GO:0042043 | neurexin family protein binding(GO:0042043) |
0.0 | 0.1 | GO:0031708 | endothelin B receptor binding(GO:0031708) |
0.0 | 0.4 | GO:0070273 | phosphatidylinositol-4-phosphate binding(GO:0070273) |
0.0 | 0.1 | GO:1990380 | Lys48-specific deubiquitinase activity(GO:1990380) |
0.0 | 0.6 | GO:0036002 | pre-mRNA binding(GO:0036002) |
0.0 | 0.2 | GO:0005161 | platelet-derived growth factor receptor binding(GO:0005161) |
0.0 | 0.3 | GO:0015269 | calcium-activated potassium channel activity(GO:0015269) |
0.0 | 0.2 | GO:0004708 | MAP kinase kinase activity(GO:0004708) |
0.0 | 0.2 | GO:0005227 | calcium activated cation channel activity(GO:0005227) |
0.0 | 0.9 | GO:0004725 | protein tyrosine phosphatase activity(GO:0004725) |
0.0 | 0.1 | GO:0032183 | SUMO binding(GO:0032183) |
0.0 | 0.0 | GO:0001588 | dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 0.9 | PID_THROMBIN_PAR4_PATHWAY | PAR4-mediated thrombin signaling events |
0.0 | 0.7 | PID_TCR_JNK_PATHWAY | JNK signaling in the CD4+ TCR pathway |
0.0 | 1.2 | PID_TRAIL_PATHWAY | TRAIL signaling pathway |
0.0 | 0.7 | PID_ERBB_NETWORK_PATHWAY | ErbB receptor signaling network |
0.0 | 0.7 | PID_HDAC_CLASSIII_PATHWAY | Signaling events mediated by HDAC Class III |
0.0 | 0.1 | PID_TCR_RAS_PATHWAY | Ras signaling in the CD4+ TCR pathway |
0.0 | 0.2 | PID_FGF_PATHWAY | FGF signaling pathway |
0.0 | 0.4 | PID_ERB_GENOMIC_PATHWAY | Validated nuclear estrogen receptor beta network |
0.0 | 0.2 | PID_FOXM1_PATHWAY | FOXM1 transcription factor network |
0.0 | 0.3 | PID_P38_GAMMA_DELTA_PATHWAY | Signaling mediated by p38-gamma and p38-delta |
0.0 | 0.7 | PID_ECADHERIN_STABILIZATION_PATHWAY | Stabilization and expansion of the E-cadherin adherens junction |
0.0 | 0.7 | PID_ARF6_PATHWAY | Arf6 signaling events |
0.0 | 0.3 | PID_GLYPICAN_1PATHWAY | Glypican 1 network |
0.0 | 0.6 | ST_DIFFERENTIATION_PATHWAY_IN_PC12_CELLS | Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway. |
0.0 | 0.2 | PID_HIF1A_PATHWAY | Hypoxic and oxygen homeostasis regulation of HIF-1-alpha |
0.0 | 1.0 | PID_ERA_GENOMIC_PATHWAY | Validated nuclear estrogen receptor alpha network |
Gene overrepresentation in C2:CP:REACTOME category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 1.3 | REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS | Genes involved in Passive Transport by Aquaporins |
0.1 | 0.9 | REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE | Genes involved in Regulation of Insulin Secretion by Acetylcholine |
0.1 | 2.5 | REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS | Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits |
0.0 | 0.8 | REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS | Genes involved in VEGF ligand-receptor interactions |
0.0 | 1.2 | REACTOME_SIGNALING_BY_NODAL | Genes involved in Signaling by NODAL |
0.0 | 1.2 | REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA | Genes involved in Circadian Repression of Expression by REV-ERBA |
0.0 | 0.5 | REACTOME_GLYCOPROTEIN_HORMONES | Genes involved in Glycoprotein hormones |
0.0 | 0.4 | REACTOME_SYNTHESIS_OF_PIPS_AT_THE_LATE_ENDOSOME_MEMBRANE | Genes involved in Synthesis of PIPs at the late endosome membrane |
0.0 | 1.1 | REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |
0.0 | 0.6 | REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS | Genes involved in Na+/Cl- dependent neurotransmitter transporters |
0.0 | 0.5 | REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GIP | Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) |
0.0 | 1.5 | REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS | Genes involved in Voltage gated Potassium channels |
0.0 | 1.3 | REACTOME_SPHINGOLIPID_METABOLISM | Genes involved in Sphingolipid metabolism |
0.0 | 0.3 | REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA | Genes involved in Activation of Chaperone Genes by ATF6-alpha |
0.0 | 0.4 | REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT | Genes involved in Organic cation/anion/zwitterion transport |
0.0 | 0.6 | REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING | Genes involved in Insulin Synthesis and Processing |
0.0 | 0.1 | REACTOME_P130CAS_LINKAGE_TO_MAPK_SIGNALING_FOR_INTEGRINS | Genes involved in p130Cas linkage to MAPK signaling for integrins |
0.0 | 1.1 | REACTOME_CHONDROITIN_SULFATE_DERMATAN_SULFATE_METABOLISM | Genes involved in Chondroitin sulfate/dermatan sulfate metabolism |
0.0 | 0.4 | REACTOME_DOWNREGULATION_OF_ERBB2_ERBB3_SIGNALING | Genes involved in Downregulation of ERBB2:ERBB3 signaling |
0.0 | 0.6 | REACTOME_TIGHT_JUNCTION_INTERACTIONS | Genes involved in Tight junction interactions |
0.0 | 0.8 | REACTOME_MYOGENESIS | Genes involved in Myogenesis |
0.0 | 0.3 | REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION | Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) |
0.0 | 0.3 | REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION | Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation |
0.0 | 0.2 | REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS | Genes involved in Elevation of cytosolic Ca2+ levels |
0.0 | 3.7 | REACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES | Genes involved in Metabolism of amino acids and derivatives |
0.0 | 0.2 | REACTOME_SYNTHESIS_OF_PIPS_AT_THE_GOLGI_MEMBRANE | Genes involved in Synthesis of PIPs at the Golgi membrane |
0.0 | 0.2 | REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY | Genes involved in Post-chaperonin tubulin folding pathway |
0.0 | 0.4 | REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
0.0 | 0.4 | REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX | Genes involved in Degradation of the extracellular matrix |