Motif ID: MYOD1
Z-value: 0.764
Transcription factors associated with MYOD1:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| MYOD1 | ENSG00000129152.3 | MYOD1 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| MYOD1 | hg19_v2_chr11_+_17741111_17741124 | 0.01 | 9.7e-01 | Click! |
Top targets:
Showing 1 to 20 of 200 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 167 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 4.2 | GO:0045329 | carnitine biosynthetic process(GO:0045329) |
| 0.0 | 2.9 | GO:0001578 | microtubule bundle formation(GO:0001578) |
| 0.0 | 2.4 | GO:0007585 | respiratory gaseous exchange(GO:0007585) |
| 0.1 | 2.0 | GO:0045603 | positive regulation of endothelial cell differentiation(GO:0045603) |
| 0.1 | 1.9 | GO:0036159 | inner dynein arm assembly(GO:0036159) |
| 0.1 | 1.9 | GO:0003084 | positive regulation of systemic arterial blood pressure(GO:0003084) |
| 0.6 | 1.8 | GO:0090076 | relaxation of skeletal muscle(GO:0090076) |
| 0.4 | 1.6 | GO:0018032 | protein amidation(GO:0018032) |
| 0.1 | 1.6 | GO:0010804 | negative regulation of tumor necrosis factor-mediated signaling pathway(GO:0010804) |
| 0.1 | 1.4 | GO:0051255 | spindle midzone assembly(GO:0051255) |
| 0.0 | 1.4 | GO:0010842 | retina layer formation(GO:0010842) |
| 0.3 | 1.3 | GO:0015670 | carbon dioxide transport(GO:0015670) |
| 0.0 | 1.3 | GO:0010862 | positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862) |
| 0.0 | 1.3 | GO:0032392 | DNA geometric change(GO:0032392) |
| 0.2 | 1.2 | GO:0023021 | termination of signal transduction(GO:0023021) |
| 0.1 | 1.2 | GO:0015705 | iodide transport(GO:0015705) |
| 0.1 | 1.2 | GO:0040037 | negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037) |
| 0.1 | 1.2 | GO:0071985 | multivesicular body sorting pathway(GO:0071985) |
| 0.3 | 1.0 | GO:1900073 | regulation of neuromuscular synaptic transmission(GO:1900073) positive regulation of neuromuscular synaptic transmission(GO:1900075) |
| 0.1 | 1.0 | GO:0043353 | enucleate erythrocyte differentiation(GO:0043353) |
Gene overrepresentation in cellular_component category:
Showing 1 to 20 of 60 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 3.1 | GO:0097427 | microtubule bundle(GO:0097427) |
| 0.2 | 2.4 | GO:0071953 | elastic fiber(GO:0071953) |
| 0.0 | 2.2 | GO:0005790 | smooth endoplasmic reticulum(GO:0005790) |
| 0.0 | 1.9 | GO:0043204 | perikaryon(GO:0043204) |
| 0.0 | 1.6 | GO:0051233 | spindle midzone(GO:0051233) |
| 0.0 | 1.6 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
| 0.0 | 1.6 | GO:0005923 | bicellular tight junction(GO:0005923) |
| 0.0 | 1.5 | GO:0009925 | basal plasma membrane(GO:0009925) |
| 0.0 | 1.5 | GO:0031526 | brush border membrane(GO:0031526) |
| 0.2 | 1.3 | GO:1990393 | 3M complex(GO:1990393) |
| 0.0 | 1.2 | GO:0042599 | lamellar body(GO:0042599) |
| 0.0 | 1.2 | GO:0034451 | centriolar satellite(GO:0034451) |
| 0.0 | 1.1 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) |
| 0.1 | 1.0 | GO:0099634 | postsynaptic specialization membrane(GO:0099634) |
| 0.3 | 0.9 | GO:0005667 | transcription factor complex(GO:0005667) |
| 0.1 | 0.9 | GO:0070695 | FHF complex(GO:0070695) |
| 0.0 | 0.8 | GO:0034706 | sodium channel complex(GO:0034706) |
| 0.0 | 0.8 | GO:0000145 | exocyst(GO:0000145) |
| 0.0 | 0.7 | GO:0097440 | apical dendrite(GO:0097440) |
| 0.1 | 0.6 | GO:0090498 | extrinsic component of Golgi membrane(GO:0090498) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 123 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.1 | 4.2 | GO:0008336 | gamma-butyrobetaine dioxygenase activity(GO:0008336) |
| 0.0 | 2.9 | GO:0070888 | E-box binding(GO:0070888) |
| 0.0 | 2.3 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
| 0.1 | 2.2 | GO:0086008 | voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008) |
| 0.6 | 1.9 | GO:0003845 | 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845) |
| 0.0 | 1.7 | GO:0005160 | transforming growth factor beta receptor binding(GO:0005160) |
| 0.4 | 1.6 | GO:0004504 | peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598) |
| 0.0 | 1.5 | GO:0051393 | alpha-actinin binding(GO:0051393) |
| 0.0 | 1.4 | GO:0008301 | DNA binding, bending(GO:0008301) |
| 0.1 | 1.3 | GO:0004767 | sphingomyelin phosphodiesterase activity(GO:0004767) |
| 0.1 | 1.3 | GO:0015250 | water channel activity(GO:0015250) |
| 0.2 | 1.2 | GO:0015111 | iodide transmembrane transporter activity(GO:0015111) |
| 0.1 | 1.2 | GO:0031435 | mitogen-activated protein kinase kinase kinase binding(GO:0031435) |
| 0.0 | 1.2 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
| 0.0 | 1.1 | GO:0008138 | protein tyrosine/serine/threonine phosphatase activity(GO:0008138) |
| 0.1 | 1.0 | GO:0005344 | oxygen transporter activity(GO:0005344) |
| 0.0 | 1.0 | GO:0043495 | protein anchor(GO:0043495) |
| 0.0 | 0.9 | GO:0005251 | delayed rectifier potassium channel activity(GO:0005251) |
| 0.0 | 0.9 | GO:0051959 | dynein light intermediate chain binding(GO:0051959) |
| 0.0 | 0.9 | GO:0016831 | carboxy-lyase activity(GO:0016831) |
Gene overrepresentation in C2:CP category:
Showing 1 to 16 of 16 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.2 | PID_TRAIL_PATHWAY | TRAIL signaling pathway |
| 0.0 | 1.0 | PID_ERA_GENOMIC_PATHWAY | Validated nuclear estrogen receptor alpha network |
| 0.0 | 0.9 | PID_THROMBIN_PAR4_PATHWAY | PAR4-mediated thrombin signaling events |
| 0.0 | 0.7 | PID_TCR_JNK_PATHWAY | JNK signaling in the CD4+ TCR pathway |
| 0.0 | 0.7 | PID_ERBB_NETWORK_PATHWAY | ErbB receptor signaling network |
| 0.0 | 0.7 | PID_HDAC_CLASSIII_PATHWAY | Signaling events mediated by HDAC Class III |
| 0.0 | 0.7 | PID_ECADHERIN_STABILIZATION_PATHWAY | Stabilization and expansion of the E-cadherin adherens junction |
| 0.0 | 0.7 | PID_ARF6_PATHWAY | Arf6 signaling events |
| 0.0 | 0.6 | ST_DIFFERENTIATION_PATHWAY_IN_PC12_CELLS | Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway. |
| 0.0 | 0.4 | PID_ERB_GENOMIC_PATHWAY | Validated nuclear estrogen receptor beta network |
| 0.0 | 0.3 | PID_P38_GAMMA_DELTA_PATHWAY | Signaling mediated by p38-gamma and p38-delta |
| 0.0 | 0.3 | PID_GLYPICAN_1PATHWAY | Glypican 1 network |
| 0.0 | 0.2 | PID_FGF_PATHWAY | FGF signaling pathway |
| 0.0 | 0.2 | PID_FOXM1_PATHWAY | FOXM1 transcription factor network |
| 0.0 | 0.2 | PID_HIF1A_PATHWAY | Hypoxic and oxygen homeostasis regulation of HIF-1-alpha |
| 0.0 | 0.1 | PID_TCR_RAS_PATHWAY | Ras signaling in the CD4+ TCR pathway |
Gene overrepresentation in C2:CP:REACTOME category:
Showing 1 to 20 of 29 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 3.7 | REACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES | Genes involved in Metabolism of amino acids and derivatives |
| 0.1 | 2.5 | REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS | Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits |
| 0.0 | 1.5 | REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS | Genes involved in Voltage gated Potassium channels |
| 0.1 | 1.3 | REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS | Genes involved in Passive Transport by Aquaporins |
| 0.0 | 1.3 | REACTOME_SPHINGOLIPID_METABOLISM | Genes involved in Sphingolipid metabolism |
| 0.0 | 1.2 | REACTOME_SIGNALING_BY_NODAL | Genes involved in Signaling by NODAL |
| 0.0 | 1.2 | REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA | Genes involved in Circadian Repression of Expression by REV-ERBA |
| 0.0 | 1.1 | REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |
| 0.0 | 1.1 | REACTOME_CHONDROITIN_SULFATE_DERMATAN_SULFATE_METABOLISM | Genes involved in Chondroitin sulfate/dermatan sulfate metabolism |
| 0.1 | 0.9 | REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE | Genes involved in Regulation of Insulin Secretion by Acetylcholine |
| 0.0 | 0.8 | REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS | Genes involved in VEGF ligand-receptor interactions |
| 0.0 | 0.8 | REACTOME_MYOGENESIS | Genes involved in Myogenesis |
| 0.0 | 0.6 | REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS | Genes involved in Na+/Cl- dependent neurotransmitter transporters |
| 0.0 | 0.6 | REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING | Genes involved in Insulin Synthesis and Processing |
| 0.0 | 0.6 | REACTOME_TIGHT_JUNCTION_INTERACTIONS | Genes involved in Tight junction interactions |
| 0.0 | 0.5 | REACTOME_GLYCOPROTEIN_HORMONES | Genes involved in Glycoprotein hormones |
| 0.0 | 0.5 | REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GIP | Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) |
| 0.0 | 0.4 | REACTOME_SYNTHESIS_OF_PIPS_AT_THE_LATE_ENDOSOME_MEMBRANE | Genes involved in Synthesis of PIPs at the late endosome membrane |
| 0.0 | 0.4 | REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT | Genes involved in Organic cation/anion/zwitterion transport |
| 0.0 | 0.4 | REACTOME_DOWNREGULATION_OF_ERBB2_ERBB3_SIGNALING | Genes involved in Downregulation of ERBB2:ERBB3 signaling |
