Motif ID: MZF1

Z-value: 0.620


Transcription factors associated with MZF1:

Gene SymbolEntrez IDGene Name
MZF1 ENSG00000099326.4 MZF1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
MZF1hg19_v2_chr19_-_59084922_59084947-0.009.9e-01Click!


Activity profile for motif MZF1.

activity profile for motif MZF1


Sorted Z-values histogram for motif MZF1

Sorted Z-values for motif MZF1



Network of associatons between targets according to the STRING database.



First level regulatory network of MZF1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_150208320 1.111 ENST00000534220.1
ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr19_-_51472823 1.093 ENST00000310157.2
KLK6
kallikrein-related peptidase 6
chr6_-_32157947 0.815 ENST00000375050.4
PBX2
pre-B-cell leukemia homeobox 2
chr5_-_127873659 0.579 ENST00000262464.4
FBN2
fibrillin 2
chr1_-_205419053 0.564 ENST00000367154.1
LEMD1
LEM domain containing 1
chr11_-_2160180 0.525 ENST00000381406.4
IGF2
insulin-like growth factor 2 (somatomedin A)
chr6_-_114664180 0.512 ENST00000312719.5
HS3ST5
heparan sulfate (glucosamine) 3-O-sulfotransferase 5
chr17_+_39969183 0.510 ENST00000321562.4
FKBP10
FK506 binding protein 10, 65 kDa
chr17_+_42634844 0.499 ENST00000315323.3
FZD2
frizzled family receptor 2
chr17_+_76210267 0.493 ENST00000301633.4
ENST00000350051.3
ENST00000374948.2
ENST00000590449.1
BIRC5



baculoviral IAP repeat containing 5



chr19_+_35645817 0.492 ENST00000423817.3
FXYD5
FXYD domain containing ion transport regulator 5
chr19_+_35645618 0.475 ENST00000392218.2
ENST00000543307.1
ENST00000392219.2
ENST00000541435.2
ENST00000590686.1
ENST00000342879.3
ENST00000588699.1
FXYD5






FXYD domain containing ion transport regulator 5






chr10_+_31608054 0.448 ENST00000320985.10
ENST00000361642.5
ENST00000560721.2
ENST00000558440.1
ENST00000424869.1
ENST00000542815.3
ZEB1





zinc finger E-box binding homeobox 1





chr14_+_24867992 0.437 ENST00000382554.3
NYNRIN
NYN domain and retroviral integrase containing
chr19_-_49015050 0.431 ENST00000600059.1
LMTK3
lemur tyrosine kinase 3
chr2_-_72375167 0.409 ENST00000001146.2
CYP26B1
cytochrome P450, family 26, subfamily B, polypeptide 1
chr15_-_74501360 0.388 ENST00000323940.5
STRA6
stimulated by retinoic acid 6
chr17_+_76210367 0.386 ENST00000592734.1
ENST00000587746.1
BIRC5

baculoviral IAP repeat containing 5

chr2_-_216300784 0.384 ENST00000421182.1
ENST00000432072.2
ENST00000323926.6
ENST00000336916.4
ENST00000357867.4
ENST00000359671.1
ENST00000346544.3
ENST00000345488.5
ENST00000357009.2
ENST00000446046.1
ENST00000356005.4
ENST00000443816.1
ENST00000426059.1
ENST00000354785.4
FN1













fibronectin 1













chr1_+_66999268 0.382 ENST00000371039.1
ENST00000424320.1
SGIP1

SH3-domain GRB2-like (endophilin) interacting protein 1

chr1_-_150208291 0.381 ENST00000533654.1
ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr16_+_88872176 0.381 ENST00000569140.1
CDT1
chromatin licensing and DNA replication factor 1
chr8_+_80523962 0.380 ENST00000518491.1
STMN2
stathmin-like 2
chr10_+_120967072 0.378 ENST00000392870.2
GRK5
G protein-coupled receptor kinase 5
chr7_-_94953878 0.378 ENST00000222381.3
PON1
paraoxonase 1
chr7_-_19813192 0.376 ENST00000422233.1
ENST00000433641.1
TMEM196

transmembrane protein 196

chr10_+_114710425 0.371 ENST00000352065.5
ENST00000369395.1
TCF7L2

transcription factor 7-like 2 (T-cell specific, HMG-box)

chr17_-_36904437 0.362 ENST00000585100.1
ENST00000360797.2
ENST00000578109.1
ENST00000579882.1
PCGF2



polycomb group ring finger 2



chr1_+_66999799 0.361 ENST00000371035.3
ENST00000371036.3
ENST00000371037.4
SGIP1


SH3-domain GRB2-like (endophilin) interacting protein 1


chr18_-_6414884 0.347 ENST00000317931.7
ENST00000284898.6
ENST00000400104.3
L3MBTL4


l(3)mbt-like 4 (Drosophila)


chr11_+_47279504 0.336 ENST00000441012.2
ENST00000437276.1
ENST00000436029.1
ENST00000467728.1
ENST00000405853.3
NR1H3




nuclear receptor subfamily 1, group H, member 3




chr19_-_14201507 0.331 ENST00000533683.2
SAMD1
sterile alpha motif domain containing 1
chr14_-_36277857 0.322 ENST00000553892.1
ENST00000382366.3
RALGAPA1

Ral GTPase activating protein, alpha subunit 1 (catalytic)

chr9_+_128509624 0.321 ENST00000342287.5
ENST00000373487.4
PBX3

pre-B-cell leukemia homeobox 3

chr4_+_37892682 0.321 ENST00000508802.1
ENST00000261439.4
ENST00000402522.1
TBC1D1


TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1


chr8_-_95907423 0.320 ENST00000396133.3
ENST00000308108.4
CCNE2

cyclin E2

chr1_-_150208363 0.319 ENST00000436748.2
ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr15_+_75640068 0.319 ENST00000565051.1
ENST00000564257.1
ENST00000567005.1
NEIL1


nei endonuclease VIII-like 1 (E. coli)


chr14_-_76447336 0.318 ENST00000556285.1
TGFB3
transforming growth factor, beta 3
chr2_+_210636697 0.317 ENST00000439458.1
ENST00000272845.6
UNC80

unc-80 homolog (C. elegans)

chr1_+_32084794 0.315 ENST00000373705.1
HCRTR1
hypocretin (orexin) receptor 1
chr11_-_123525289 0.311 ENST00000392770.2
ENST00000299333.3
ENST00000530277.1
SCN3B


sodium channel, voltage-gated, type III, beta subunit


chr11_-_115375107 0.310 ENST00000545380.1
ENST00000452722.3
ENST00000537058.1
ENST00000536727.1
ENST00000542447.2
ENST00000331581.6
CADM1





cell adhesion molecule 1





chr15_-_75017711 0.304 ENST00000567032.1
ENST00000564596.1
ENST00000566503.1
ENST00000395049.4
ENST00000395048.2
ENST00000379727.3
CYP1A1





cytochrome P450, family 1, subfamily A, polypeptide 1





chr7_+_97361218 0.304 ENST00000319273.5
TAC1
tachykinin, precursor 1
chr7_-_112579869 0.300 ENST00000297145.4
C7orf60
chromosome 7 open reading frame 60
chr1_-_235667716 0.296 ENST00000313984.3
ENST00000366600.3
B3GALNT2

beta-1,3-N-acetylgalactosaminyltransferase 2

chr15_-_71055769 0.296 ENST00000539319.1
UACA
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr18_+_56530136 0.293 ENST00000591083.1
ZNF532
zinc finger protein 532
chr17_+_1959369 0.288 ENST00000576444.1
ENST00000322941.3
HIC1

hypermethylated in cancer 1

chr1_-_244013384 0.280 ENST00000366539.1
AKT3
v-akt murine thymoma viral oncogene homolog 3
chrX_-_48328631 0.280 ENST00000429543.1
ENST00000317669.5
SLC38A5

solute carrier family 38, member 5

chr2_-_163695128 0.275 ENST00000332142.5
KCNH7
potassium voltage-gated channel, subfamily H (eag-related), member 7
chr2_-_61765315 0.274 ENST00000406957.1
ENST00000401558.2
XPO1

exportin 1 (CRM1 homolog, yeast)

chr7_+_94285637 0.273 ENST00000482108.1
ENST00000488574.1
PEG10

paternally expressed 10

chr7_-_143059845 0.272 ENST00000443739.2
FAM131B
family with sequence similarity 131, member B
chr12_-_48152428 0.272 ENST00000449771.2
ENST00000395358.3
RAPGEF3

Rap guanine nucleotide exchange factor (GEF) 3

chr3_-_123168551 0.272 ENST00000462833.1
ADCY5
adenylate cyclase 5
chr10_-_75401500 0.271 ENST00000359322.4
MYOZ1
myozenin 1
chr2_-_234763147 0.271 ENST00000411486.2
ENST00000432087.1
ENST00000441687.1
ENST00000414924.1
HJURP



Holliday junction recognition protein



chr19_+_10381769 0.269 ENST00000423829.2
ENST00000588645.1
ICAM1

intercellular adhesion molecule 1

chr2_+_45168875 0.268 ENST00000260653.3
SIX3
SIX homeobox 3
chr7_-_94285402 0.267 ENST00000428696.2
ENST00000445866.2
SGCE

sarcoglycan, epsilon

chr10_+_114710516 0.266 ENST00000542695.1
ENST00000346198.4
TCF7L2

transcription factor 7-like 2 (T-cell specific, HMG-box)

chr6_-_42419649 0.265 ENST00000372922.4
ENST00000541110.1
ENST00000372917.4
TRERF1


transcriptional regulating factor 1


chr8_+_27632083 0.265 ENST00000519637.1
ESCO2
establishment of sister chromatid cohesion N-acetyltransferase 2
chr10_+_105314881 0.264 ENST00000437579.1
NEURL
neuralized E3 ubiquitin protein ligase 1
chr7_-_28220354 0.264 ENST00000283928.5
JAZF1
JAZF zinc finger 1
chrX_+_136648297 0.263 ENST00000287538.5
ZIC3
Zic family member 3
chr7_-_94285511 0.261 ENST00000265735.7
SGCE
sarcoglycan, epsilon
chr7_-_94285472 0.258 ENST00000437425.2
ENST00000447873.1
ENST00000415788.2
SGCE


sarcoglycan, epsilon


chr14_+_75745477 0.257 ENST00000303562.4
ENST00000554617.1
ENST00000554212.1
ENST00000535987.1
ENST00000555242.1
FOS




FBJ murine osteosarcoma viral oncogene homolog




chr7_+_143079000 0.256 ENST00000392910.2
ZYX
zyxin
chr3_+_63428752 0.256 ENST00000295894.5
SYNPR
synaptoporin
chr19_-_54872556 0.255 ENST00000444687.1
LAIR1
leukocyte-associated immunoglobulin-like receptor 1
chr3_+_63428982 0.251 ENST00000479198.1
ENST00000460711.1
ENST00000465156.1
SYNPR


synaptoporin


chr19_-_38916802 0.250 ENST00000587738.1
RASGRP4
RAS guanyl releasing protein 4
chr21_-_44496441 0.249 ENST00000359624.3
ENST00000352178.5
CBS

cystathionine-beta-synthase

chr5_+_66254698 0.247 ENST00000405643.1
ENST00000407621.1
ENST00000432426.1
MAST4


microtubule associated serine/threonine kinase family member 4


chr22_-_37403839 0.245 ENST00000402860.3
ENST00000381821.1
TEX33

testis expressed 33

chr18_+_19749386 0.245 ENST00000269216.3
GATA6
GATA binding protein 6
chrX_-_128657457 0.245 ENST00000371121.3
ENST00000371123.1
ENST00000371122.4
SMARCA1


SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1


chr22_-_37403858 0.244 ENST00000405091.2
TEX33
testis expressed 33
chr2_-_26205340 0.242 ENST00000264712.3
KIF3C
kinesin family member 3C
chr15_+_89346699 0.242 ENST00000558207.1
ACAN
aggrecan
chr19_-_40724246 0.241 ENST00000311308.6
TTC9B
tetratricopeptide repeat domain 9B
chr1_-_150208412 0.239 ENST00000532744.1
ENST00000369114.5
ENST00000369115.2
ENST00000369116.4
ANP32E



acidic (leucine-rich) nuclear phosphoprotein 32 family, member E



chr20_-_42816206 0.238 ENST00000372980.3
JPH2
junctophilin 2
chr17_-_40913275 0.238 ENST00000589716.1
ENST00000360166.3
RAMP2-AS1

RAMP2 antisense RNA 1

chr17_+_40913210 0.236 ENST00000253796.5
RAMP2
receptor (G protein-coupled) activity modifying protein 2
chr20_+_35201857 0.235 ENST00000373874.2
TGIF2
TGFB-induced factor homeobox 2
chr3_+_111393501 0.235 ENST00000393934.3
PLCXD2
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr12_+_49717019 0.230 ENST00000549275.1
ENST00000551245.1
ENST00000380327.5
ENST00000548311.1
ENST00000550346.1
ENST00000550709.1
ENST00000549534.1
ENST00000257909.3
TROAP







trophinin associated protein







chr19_+_34287174 0.229 ENST00000587559.1
ENST00000588637.1
KCTD15

potassium channel tetramerization domain containing 15

chr12_+_49717081 0.229 ENST00000547807.1
ENST00000551567.1
TROAP

trophinin associated protein

chr5_+_52776449 0.228 ENST00000396947.3
FST
follistatin
chr20_+_34742650 0.228 ENST00000373945.1
ENST00000338074.2
EPB41L1

erythrocyte membrane protein band 4.1-like 1

chr20_+_44035847 0.225 ENST00000372712.2
DBNDD2
dysbindin (dystrobrevin binding protein 1) domain containing 2
chr7_-_143059780 0.222 ENST00000409578.1
ENST00000409346.1
FAM131B

family with sequence similarity 131, member B

chr2_-_161056762 0.222 ENST00000428609.2
ENST00000409967.2
ITGB6

integrin, beta 6

chr17_-_42031300 0.222 ENST00000592796.1
PYY
peptide YY
chr12_-_57882577 0.218 ENST00000393797.2
ARHGAP9
Rho GTPase activating protein 9
chr5_+_133861790 0.217 ENST00000395003.1
PHF15
jade family PHD finger 2
chr13_-_36050819 0.216 ENST00000379919.4
MAB21L1
mab-21-like 1 (C. elegans)
chr19_-_47975417 0.210 ENST00000236877.6
SLC8A2
solute carrier family 8 (sodium/calcium exchanger), member 2
chr6_+_7108210 0.209 ENST00000467782.1
ENST00000334984.6
ENST00000349384.6
RREB1


ras responsive element binding protein 1


chr14_+_95027772 0.209 ENST00000555095.1
ENST00000298841.5
ENST00000554220.1
ENST00000553780.1
SERPINA4

SERPINA5

serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4

serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5

chr8_+_27632047 0.208 ENST00000397418.2
ESCO2
establishment of sister chromatid cohesion N-acetyltransferase 2
chr19_-_41859814 0.205 ENST00000221930.5
TGFB1
transforming growth factor, beta 1
chr12_-_22094336 0.204 ENST00000326684.4
ABCC9
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr1_-_93426998 0.203 ENST00000370310.4
FAM69A
family with sequence similarity 69, member A
chr11_-_7985193 0.203 ENST00000328600.2
NLRP10
NLR family, pyrin domain containing 10
chr5_+_82767284 0.203 ENST00000265077.3
VCAN
versican
chr1_-_150208498 0.202 ENST00000314136.8
ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr14_-_69445968 0.202 ENST00000438964.2
ACTN1
actinin, alpha 1
chr7_-_79082867 0.201 ENST00000419488.1
ENST00000354212.4
MAGI2

membrane associated guanylate kinase, WW and PDZ domain containing 2

chr16_-_30393752 0.199 ENST00000566517.1
ENST00000605106.1
SEPT1
SEPT1
septin 1
Uncharacterized protein
chr7_+_77167376 0.199 ENST00000435495.2
PTPN12
protein tyrosine phosphatase, non-receptor type 12
chr1_+_43766642 0.199 ENST00000372476.3
TIE1
tyrosine kinase with immunoglobulin-like and EGF-like domains 1
chr7_+_97361388 0.195 ENST00000350485.4
ENST00000346867.4
TAC1

tachykinin, precursor 1

chr4_+_169552748 0.194 ENST00000504519.1
ENST00000512127.1
PALLD

palladin, cytoskeletal associated protein

chr2_-_161056802 0.192 ENST00000283249.2
ENST00000409872.1
ITGB6

integrin, beta 6

chr19_+_926000 0.191 ENST00000263620.3
ARID3A
AT rich interactive domain 3A (BRIGHT-like)
chr12_-_57871853 0.191 ENST00000549602.1
ENST00000430041.2
ARHGAP9

Rho GTPase activating protein 9

chr1_-_24239844 0.189 ENST00000374472.4
CNR2
cannabinoid receptor 2 (macrophage)
chr12_-_4488872 0.188 ENST00000237837.1
FGF23
fibroblast growth factor 23
chr18_-_35065710 0.188 ENST00000589229.1
ENST00000587819.1
CELF4

CUGBP, Elav-like family member 4

chr7_+_114562909 0.185 ENST00000423503.1
ENST00000427207.1
MDFIC

MyoD family inhibitor domain containing

chr12_-_48152853 0.185 ENST00000171000.4
RAPGEF3
Rap guanine nucleotide exchange factor (GEF) 3
chr2_-_55647057 0.183 ENST00000436346.1
CCDC88A
coiled-coil domain containing 88A
chr1_+_91966384 0.182 ENST00000430031.2
ENST00000234626.6
CDC7

cell division cycle 7

chr14_-_69445793 0.182 ENST00000538545.2
ENST00000394419.4
ACTN1

actinin, alpha 1

chr11_-_35547151 0.180 ENST00000378878.3
ENST00000529303.1
ENST00000278360.3
PAMR1


peptidase domain containing associated with muscle regeneration 1


chr12_-_48152611 0.179 ENST00000389212.3
RAPGEF3
Rap guanine nucleotide exchange factor (GEF) 3
chr14_+_21538517 0.179 ENST00000298693.3
ARHGEF40
Rho guanine nucleotide exchange factor (GEF) 40
chrX_-_111326004 0.178 ENST00000262839.2
TRPC5
transient receptor potential cation channel, subfamily C, member 5
chr1_+_37940153 0.178 ENST00000373087.6
ZC3H12A
zinc finger CCCH-type containing 12A
chr5_+_161274940 0.178 ENST00000393943.4
GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr3_+_9975497 0.176 ENST00000397170.3
ENST00000383811.3
ENST00000452070.1
ENST00000326434.5
CRELD1



cysteine-rich with EGF-like domains 1



chr17_+_29421987 0.176 ENST00000431387.4
NF1
neurofibromin 1
chr15_+_38544476 0.176 ENST00000299084.4
SPRED1
sprouty-related, EVH1 domain containing 1
chr1_+_91966656 0.175 ENST00000428239.1
ENST00000426137.1
CDC7

cell division cycle 7

chr1_-_161102213 0.175 ENST00000458050.2
DEDD
death effector domain containing
chrX_-_110039038 0.174 ENST00000372042.1
ENST00000482160.1
ENST00000444321.2
ENST00000218054.4
CHRDL1



chordin-like 1



chr17_+_7155343 0.174 ENST00000573513.1
ENST00000354429.2
ENST00000574255.1
ENST00000396627.2
ENST00000356683.2
ELP5




elongator acetyltransferase complex subunit 5




chr17_-_48278983 0.173 ENST00000225964.5
COL1A1
collagen, type I, alpha 1
chr7_+_114562616 0.173 ENST00000448022.1
MDFIC
MyoD family inhibitor domain containing
chr14_-_69446034 0.171 ENST00000193403.6
ACTN1
actinin, alpha 1
chrX_-_110039286 0.170 ENST00000434224.1
CHRDL1
chordin-like 1
chr6_+_37137939 0.169 ENST00000373509.5
PIM1
pim-1 oncogene
chr3_+_96533413 0.169 ENST00000470610.2
ENST00000389672.5
EPHA6

EPH receptor A6

chr22_+_24322322 0.169 ENST00000215780.5
ENST00000402588.3
GSTT2

glutathione S-transferase theta 2

chr12_+_22778291 0.168 ENST00000545979.1
ETNK1
ethanolamine kinase 1
chr6_-_110500905 0.168 ENST00000392587.2
WASF1
WAS protein family, member 1
chr2_-_60780536 0.168 ENST00000538214.1
BCL11A
B-cell CLL/lymphoma 11A (zinc finger protein)
chr14_+_75746340 0.167 ENST00000555686.1
ENST00000555672.1
FOS

FBJ murine osteosarcoma viral oncogene homolog

chr2_+_48541776 0.166 ENST00000413569.1
ENST00000340553.3
FOXN2

forkhead box N2

chr12_-_118406028 0.165 ENST00000425217.1
KSR2
kinase suppressor of ras 2
chr2_-_51259528 0.165 ENST00000404971.1
NRXN1
neurexin 1
chr1_+_32538492 0.165 ENST00000336294.5
TMEM39B
transmembrane protein 39B
chr9_+_17134980 0.164 ENST00000380647.3
CNTLN
centlein, centrosomal protein
chr19_-_38916839 0.164 ENST00000433821.2
ENST00000426920.2
ENST00000587753.1
ENST00000454404.2
ENST00000293062.9
RASGRP4




RAS guanyl releasing protein 4




chr6_-_42418999 0.163 ENST00000340840.2
ENST00000354325.2
TRERF1

transcriptional regulating factor 1

chr12_-_49259643 0.162 ENST00000309739.5
RND1
Rho family GTPase 1
chr14_+_21538429 0.162 ENST00000298694.4
ENST00000555038.1
ARHGEF40

Rho guanine nucleotide exchange factor (GEF) 40

chrX_-_17878827 0.161 ENST00000360011.1
RAI2
retinoic acid induced 2
chr10_-_103603523 0.161 ENST00000370046.1
KCNIP2
Kv channel interacting protein 2
chr11_-_74442430 0.159 ENST00000376332.3
CHRDL2
chordin-like 2
chr6_+_106546808 0.159 ENST00000369089.3
PRDM1
PR domain containing 1, with ZNF domain
chr8_-_122653630 0.159 ENST00000303924.4
HAS2
hyaluronan synthase 2
chr2_+_27193480 0.158 ENST00000233121.2
ENST00000405074.3
MAPRE3

microtubule-associated protein, RP/EB family, member 3

chr1_+_145470504 0.157 ENST00000323397.4
ANKRD34A
ankyrin repeat domain 34A
chr10_+_99473455 0.157 ENST00000285605.6
MARVELD1
MARVEL domain containing 1
chr19_-_42573650 0.157 ENST00000593562.1
GRIK5
glutamate receptor, ionotropic, kainate 5
chr17_+_65373531 0.157 ENST00000580974.1
PITPNC1
phosphatidylinositol transfer protein, cytoplasmic 1
chr8_-_70747205 0.156 ENST00000260126.4
SLCO5A1
solute carrier organic anion transporter family, member 5A1
chr1_+_32084641 0.155 ENST00000373706.5
HCRTR1
hypocretin (orexin) receptor 1
chr1_-_53018654 0.154 ENST00000257177.4
ENST00000355809.4
ENST00000528642.1
ENST00000470626.1
ENST00000371544.3
ZCCHC11




zinc finger, CCHC domain containing 11




chr19_+_54412517 0.154 ENST00000391767.1
CACNG7
calcium channel, voltage-dependent, gamma subunit 7
chr6_-_32119877 0.154 ENST00000375152.2
PRRT1
proline-rich transmembrane protein 1
chr5_-_114938090 0.153 ENST00000427199.2
TICAM2
toll-like receptor adaptor molecule 2
chr19_-_38916822 0.153 ENST00000586305.1
RASGRP4
RAS guanyl releasing protein 4
chr11_-_117747434 0.151 ENST00000529335.2
ENST00000530956.1
ENST00000260282.4
FXYD6


FXYD domain containing ion transport regulator 6


chr5_-_115177496 0.150 ENST00000274459.4
ENST00000509910.1
ATG12

autophagy related 12

chr19_-_11616645 0.149 ENST00000293771.5
ZNF653
zinc finger protein 653
chr4_-_174451370 0.149 ENST00000359562.4
HAND2
heart and neural crest derivatives expressed 2
chr12_+_56137064 0.148 ENST00000257868.5
ENST00000546799.1
GDF11

growth differentiation factor 11

chr13_+_98795434 0.148 ENST00000376586.2
FARP1
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr1_+_26737292 0.148 ENST00000254231.4
LIN28A
lin-28 homolog A (C. elegans)
chr12_-_52604607 0.148 ENST00000551894.1
ENST00000553017.1
C12orf80

chromosome 12 open reading frame 80

chr3_-_179754556 0.148 ENST00000263962.8
PEX5L
peroxisomal biogenesis factor 5-like
chr2_+_177025619 0.147 ENST00000410016.1
HOXD3
homeobox D3
chr5_+_115177178 0.147 ENST00000316788.7
AP3S1
adaptor-related protein complex 3, sigma 1 subunit
chr13_+_98795505 0.147 ENST00000319562.6
FARP1
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr6_-_32119676 0.146 ENST00000211413.5
PRRT1
proline-rich transmembrane protein 1
chr11_-_64512469 0.146 ENST00000377485.1
RASGRP2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr15_-_43212836 0.145 ENST00000566931.1
ENST00000564431.1
ENST00000567274.1
TTBK2


tau tubulin kinase 2


chr7_+_143078652 0.145 ENST00000354434.4
ENST00000449423.2
ZYX

zyxin

chr4_-_165305086 0.144 ENST00000507270.1
ENST00000514618.1
ENST00000503008.1
MARCH1


membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase


chr1_+_150337100 0.144 ENST00000401000.4
RPRD2
regulation of nuclear pre-mRNA domain containing 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
0.2 0.5 GO:0000412 histone peptidyl-prolyl isomerization(GO:0000412)
0.2 0.5 GO:2000854 positive regulation of corticosterone secretion(GO:2000854)
0.2 0.6 GO:0033123 positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
0.1 0.4 GO:2001037 tongue muscle cell differentiation(GO:0035981) positive regulation of skeletal muscle fiber differentiation(GO:1902811) regulation of tongue muscle cell differentiation(GO:2001035) positive regulation of tongue muscle cell differentiation(GO:2001037)
0.1 0.8 GO:0010908 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.1 0.4 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
0.1 0.4 GO:1902595 regulation of DNA replication origin binding(GO:1902595)
0.1 0.6 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1 0.3 GO:0090341 negative regulation of secretion of lysosomal enzymes(GO:0090341)
0.1 0.6 GO:1902617 response to fluoride(GO:1902617)
0.1 0.3 GO:1903860 negative regulation of dendrite extension(GO:1903860) regulation of neuron remodeling(GO:1904799) negative regulation of neuron remodeling(GO:1904800) negative regulation of branching morphogenesis of a nerve(GO:2000173)
0.1 0.3 GO:0018894 dibenzo-p-dioxin metabolic process(GO:0018894) cellular alkene metabolic process(GO:0043449)
0.1 0.5 GO:0061143 alveolar primary septum development(GO:0061143)
0.1 0.4 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.1 0.4 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.1 0.3 GO:0014016 neuroblast differentiation(GO:0014016)
0.1 0.5 GO:0001661 conditioned taste aversion(GO:0001661)
0.1 0.2 GO:0006535 cysteine biosynthetic process from serine(GO:0006535)
0.1 0.7 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.1 0.2 GO:0032911 negative regulation of transforming growth factor beta1 production(GO:0032911)
0.1 0.5 GO:0034421 post-translational protein acetylation(GO:0034421)
0.1 0.3 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.1 0.6 GO:0010587 miRNA catabolic process(GO:0010587)
0.1 0.3 GO:0070101 positive regulation of chemokine-mediated signaling pathway(GO:0070101)
0.1 0.2 GO:0045226 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.1 0.3 GO:0048749 compound eye development(GO:0048749)
0.1 0.2 GO:0052553 induction by symbiont of host defense response(GO:0044416) induction of host immune response by virus(GO:0046730) active induction of host immune response by virus(GO:0046732) modulation by symbiont of host defense response(GO:0052031) induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553) modulation by virus of host immune response(GO:0075528) negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.1 0.3 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.1 0.2 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.1 0.2 GO:0042369 vitamin D catabolic process(GO:0042369)
0.1 0.5 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.1 0.2 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
0.1 0.2 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.1 0.2 GO:0060979 vasculogenesis involved in coronary vascular morphogenesis(GO:0060979)
0.1 0.5 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.1 0.6 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.1 0.8 GO:0060346 bone trabecula formation(GO:0060346)
0.1 1.2 GO:0016540 protein autoprocessing(GO:0016540)
0.1 0.2 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
0.1 0.3 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.0 0.4 GO:0003150 muscular septum morphogenesis(GO:0003150)
0.0 0.3 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.0 0.4 GO:0038044 transforming growth factor-beta secretion(GO:0038044)
0.0 0.3 GO:0007386 compartment pattern specification(GO:0007386)
0.0 0.2 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.0 0.4 GO:1902866 regulation of retina development in camera-type eye(GO:1902866)
0.0 0.4 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.0 0.1 GO:0016539 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
0.0 0.1 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.0 0.3 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.0 0.1 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.0 2.5 GO:0043486 histone exchange(GO:0043486)
0.0 0.1 GO:0050894 determination of affect(GO:0050894)
0.0 0.4 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.0 0.1 GO:0021816 lamellipodium assembly involved in ameboidal cell migration(GO:0003363) extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration(GO:0021816)
0.0 0.1 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
0.0 0.2 GO:0061107 seminal vesicle development(GO:0061107)
0.0 0.1 GO:0042938 dipeptide transport(GO:0042938)
0.0 0.2 GO:1903490 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
0.0 0.4 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.9 GO:1990001 inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.0 0.2 GO:0060748 tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.0 0.4 GO:0098734 macromolecule depalmitoylation(GO:0098734)
0.0 0.1 GO:0061325 cell proliferation involved in outflow tract morphogenesis(GO:0061325)
0.0 0.1 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.0 0.3 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116) neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.0 0.1 GO:1902896 terminal web assembly(GO:1902896)
0.0 0.6 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.2 GO:0051136 regulation of NK T cell differentiation(GO:0051136)
0.0 0.4 GO:0015074 DNA integration(GO:0015074)
0.0 0.4 GO:0035279 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.0 0.3 GO:0045759 negative regulation of action potential(GO:0045759)
0.0 0.1 GO:0019056 modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
0.0 0.3 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.0 0.1 GO:0008050 female courtship behavior(GO:0008050)
0.0 0.3 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055) ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.1 GO:0038163 thrombopoietin-mediated signaling pathway(GO:0038163)
0.0 0.2 GO:0070120 ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
0.0 0.1 GO:0035669 TRAM-dependent toll-like receptor signaling pathway(GO:0035668) TRAM-dependent toll-like receptor 4 signaling pathway(GO:0035669)
0.0 0.1 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)
0.0 0.1 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.0 0.1 GO:0009436 glyoxylate catabolic process(GO:0009436)
0.0 0.1 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.0 0.1 GO:0070295 renal water absorption(GO:0070295)
0.0 0.1 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.0 0.1 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
0.0 0.1 GO:1904954 canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation(GO:1904954)
0.0 0.5 GO:2000586 regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000586)
0.0 0.1 GO:1904674 positive regulation of somatic stem cell population maintenance(GO:1904674)
0.0 0.3 GO:0032074 negative regulation of nuclease activity(GO:0032074)
0.0 0.1 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
0.0 0.1 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.0 0.1 GO:1905075 occluding junction disassembly(GO:1905071) regulation of occluding junction disassembly(GO:1905073) positive regulation of occluding junction disassembly(GO:1905075)
0.0 0.1 GO:2001076 regulation of metanephric ureteric bud development(GO:2001074) positive regulation of metanephric ureteric bud development(GO:2001076)
0.0 0.2 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.0 0.1 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.0 0.1 GO:0051541 elastin metabolic process(GO:0051541)
0.0 0.4 GO:0071420 cellular response to histamine(GO:0071420)
0.0 0.1 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
0.0 0.1 GO:0090425 hepatocyte cell migration(GO:0002194) otic placode formation(GO:0043049) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.0 0.0 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.0 0.1 GO:2000821 regulation of grooming behavior(GO:2000821)
0.0 0.7 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 0.1 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.0 0.2 GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.0 0.1 GO:1990927 negative regulation of synaptic vesicle recycling(GO:1903422) negative regulation of membrane invagination(GO:1905154) calcium ion regulated lysosome exocytosis(GO:1990927)
0.0 0.2 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.0 0.2 GO:2000138 positive regulation of cell proliferation involved in heart morphogenesis(GO:2000138)
0.0 0.1 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.0 0.0 GO:2000015 regulation of determination of dorsal identity(GO:2000015)
0.0 0.3 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.3 GO:0015816 glycine transport(GO:0015816)
0.0 0.5 GO:0045187 regulation of circadian sleep/wake cycle, sleep(GO:0045187)
0.0 0.1 GO:0061312 BMP signaling pathway involved in heart development(GO:0061312)
0.0 0.0 GO:0021764 amygdala development(GO:0021764)
0.0 0.1 GO:0061153 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.0 0.4 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.1 GO:0060729 amacrine cell differentiation(GO:0035881) intestinal epithelial structure maintenance(GO:0060729)
0.0 0.2 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0 0.1 GO:0002268 follicular dendritic cell differentiation(GO:0002268)
0.0 0.2 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.0 0.1 GO:0035544 negative regulation of SNARE complex assembly(GO:0035544)
0.0 0.7 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.0 0.1 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.0 0.3 GO:0038092 nodal signaling pathway(GO:0038092)
0.0 0.2 GO:0016322 neuron remodeling(GO:0016322)
0.0 0.2 GO:2000318 positive regulation of T-helper 17 type immune response(GO:2000318)
0.0 0.1 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.1 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.0 0.0 GO:0003241 growth involved in heart morphogenesis(GO:0003241)
0.0 0.0 GO:0032224 positive regulation of synaptic transmission, cholinergic(GO:0032224)
0.0 0.0 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.0 0.2 GO:0000733 DNA strand renaturation(GO:0000733)
0.0 0.1 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0 0.2 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.1 GO:0097091 synaptic vesicle clustering(GO:0097091)
0.0 0.0 GO:0003285 septum secundum development(GO:0003285)
0.0 0.1 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.0 0.1 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.0 0.1 GO:0003415 chondrocyte hypertrophy(GO:0003415)
0.0 0.1 GO:0002501 peptide antigen assembly with MHC protein complex(GO:0002501)
0.0 0.2 GO:0051665 membrane raft localization(GO:0051665)
0.0 0.0 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.0 0.1 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.0 0.1 GO:0006226 dUMP biosynthetic process(GO:0006226)
0.0 0.1 GO:0032072 plasmacytoid dendritic cell activation(GO:0002270) T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055) regulation of restriction endodeoxyribonuclease activity(GO:0032072) positive regulation of toll-like receptor 9 signaling pathway(GO:0034165)
0.0 0.1 GO:0032484 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.0 0.1 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.1 GO:0071393 cellular response to progesterone stimulus(GO:0071393)
0.0 0.0 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.0 0.1 GO:1902952 positive regulation of dendritic spine maintenance(GO:1902952)
0.0 0.1 GO:0060290 transdifferentiation(GO:0060290)
0.0 0.1 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0 0.1 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.0 0.1 GO:0060689 cell differentiation involved in salivary gland development(GO:0060689)
0.0 0.0 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.0 0.1 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0 0.3 GO:0044804 nucleophagy(GO:0044804)
0.0 0.0 GO:0010816 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.0 0.0 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.0 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0 0.0 GO:1904862 inhibitory synapse assembly(GO:1904862)
0.0 0.1 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 0.1 GO:1902412 regulation of mitotic cytokinesis(GO:1902412)
0.0 0.0 GO:0044034 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.0 0.0 GO:0061314 Notch signaling involved in heart development(GO:0061314)
0.0 0.2 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.0 GO:0061198 fungiform papilla formation(GO:0061198)
0.0 0.0 GO:0051106 positive regulation of DNA ligation(GO:0051106)
0.0 0.1 GO:0007566 embryo implantation(GO:0007566)
0.0 0.1 GO:0060087 relaxation of vascular smooth muscle(GO:0060087)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.1 0.8 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.1 0.9 GO:0032133 chromosome passenger complex(GO:0032133)
0.1 2.3 GO:0000812 Swr1 complex(GO:0000812)
0.1 0.2 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)
0.1 0.3 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
0.1 0.7 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 0.2 GO:0036025 protein C inhibitor-TMPRSS7 complex(GO:0036024) protein C inhibitor-TMPRSS11E complex(GO:0036025) protein C inhibitor-PLAT complex(GO:0036026) protein C inhibitor-PLAU complex(GO:0036027) protein C inhibitor-thrombin complex(GO:0036028) protein C inhibitor-KLK3 complex(GO:0036029) protein C inhibitor-plasma kallikrein complex(GO:0036030) serine protease inhibitor complex(GO:0097180) protein C inhibitor-coagulation factor V complex(GO:0097181) protein C inhibitor-coagulation factor Xa complex(GO:0097182) protein C inhibitor-coagulation factor XI complex(GO:0097183)
0.1 0.1 GO:0000798 nuclear cohesin complex(GO:0000798)
0.1 0.5 GO:0035976 AP1 complex(GO:0035976)
0.0 0.2 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.3 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.0 0.2 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0 0.6 GO:0005916 fascia adherens(GO:0005916)
0.0 0.3 GO:1903440 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.0 0.8 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 0.4 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.2 GO:0070435 Shc-EGFR complex(GO:0070435)
0.0 0.3 GO:0001739 sex chromatin(GO:0001739)
0.0 0.4 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.5 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.1 GO:0044308 axonal spine(GO:0044308)
0.0 0.3 GO:0016589 NURF complex(GO:0016589)
0.0 0.2 GO:0014802 terminal cisterna(GO:0014802)
0.0 0.2 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.4 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.2 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.1 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.0 0.1 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.0 0.2 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.5 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.3 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.0 0.5 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.1 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.0 0.1 GO:0072487 MSL complex(GO:0072487)
0.0 0.3 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.5 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.1 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.1 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 0.0 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.1 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.1 GO:0031415 NatA complex(GO:0031415)
0.0 0.0 GO:0031302 intrinsic component of endosome membrane(GO:0031302)
0.0 0.1 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 0.3 GO:0031143 pseudopodium(GO:0031143)
0.0 0.1 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.0 GO:0036398 TCR signalosome(GO:0036398)
0.0 0.2 GO:0031209 SCAR complex(GO:0031209)
0.0 0.1 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.0 0.1 GO:0030055 cell-substrate junction(GO:0030055)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.1 0.4 GO:0102007 lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.1 0.5 GO:0016499 orexin receptor activity(GO:0016499)
0.1 0.3 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.1 0.2 GO:0050421 cystathionine beta-synthase activity(GO:0004122) oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor(GO:0016662) nitrite reductase (NO-forming) activity(GO:0050421) carbon monoxide binding(GO:0070025) nitrite reductase activity(GO:0098809)
0.1 0.6 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.1 0.4 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.1 0.3 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.1 0.4 GO:0042835 BRE binding(GO:0042835)
0.1 0.3 GO:0032810 sterol response element binding(GO:0032810)
0.1 0.3 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 0.3 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.1 0.5 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.1 0.2 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.6 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 0.5 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1 0.3 GO:0051373 FATZ binding(GO:0051373)
0.1 0.2 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.1 0.3 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.0 0.4 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.3 GO:0019776 Atg8 ligase activity(GO:0019776)
0.0 0.2 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.4 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.0 0.1 GO:0031877 somatostatin receptor binding(GO:0031877)
0.0 0.3 GO:0097643 amylin receptor activity(GO:0097643)
0.0 0.8 GO:0070016 gamma-catenin binding(GO:0045295) armadillo repeat domain binding(GO:0070016)
0.0 0.2 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
0.0 0.1 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.0 0.2 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.0 0.1 GO:0030226 apolipoprotein receptor activity(GO:0030226)
0.0 0.1 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
0.0 0.2 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.0 0.4 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.1 GO:0052836 inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.0 0.1 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.0 0.2 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.0 0.2 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.7 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.2 GO:0048408 epidermal growth factor binding(GO:0048408)
0.0 0.2 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.1 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.0 0.1 GO:0033823 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
0.0 0.1 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.0 2.1 GO:0019212 phosphatase inhibitor activity(GO:0019212)
0.0 0.1 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.1 GO:0004132 dCMP deaminase activity(GO:0004132)
0.0 0.3 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.2 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.0 0.3 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.1 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.2 GO:0034711 inhibin binding(GO:0034711)
0.0 0.1 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.4 GO:0048185 activin binding(GO:0048185)
0.0 0.6 GO:0017166 vinculin binding(GO:0017166)
0.0 0.1 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.3 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 1.2 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.6 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.2 GO:0032190 acrosin binding(GO:0032190)
0.0 0.2 GO:0036310 annealing helicase activity(GO:0036310)
0.0 0.1 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 0.2 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.3 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.5 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.1 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 0.1 GO:0015185 gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.0 0.1 GO:0008453 alanine-glyoxylate transaminase activity(GO:0008453)
0.0 0.2 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.0 0.1 GO:0036132 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.0 0.5 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.5 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 0.3 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.2 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
0.0 0.4 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0 0.1 GO:0004743 pyruvate kinase activity(GO:0004743)
0.0 0.1 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.0 0.1 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.0 0.1 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.1 GO:0098821 BMP receptor activity(GO:0098821)
0.0 0.1 GO:0050436 microfibril binding(GO:0050436)
0.0 0.1 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.2 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.5 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.2 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 0.2 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.1 GO:0097108 hedgehog family protein binding(GO:0097108)
0.0 0.2 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.7 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.1 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.0 0.2 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.1 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.8 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.1 GO:0019960 C-X3-C chemokine binding(GO:0019960) protein antigen binding(GO:1990405)
0.0 0.2 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 0.1 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.4 GO:0051183 vitamin transporter activity(GO:0051183)
0.0 0.1 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.0 GO:0017129 triglyceride binding(GO:0017129)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.1 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.1 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.0 GO:0003875 ADP-ribosylarginine hydrolase activity(GO:0003875)
0.0 0.1 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.0 0.5 GO:0070412 R-SMAD binding(GO:0070412)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 PID_TCR_RAS_PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.7 ST_INTERLEUKIN_4_PATHWAY Interleukin 4 (IL-4) Pathway
0.0 1.5 PID_ALPHA_SYNUCLEIN_PATHWAY Alpha-synuclein signaling
0.0 0.5 PID_TCR_JNK_PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.7 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.0 0.9 PID_LYMPH_ANGIOGENESIS_PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 0.5 PID_ECADHERIN_KERATINOCYTE_PATHWAY E-cadherin signaling in keratinocytes
0.0 0.9 PID_RAS_PATHWAY Regulation of Ras family activation
0.0 0.3 PID_RANBP2_PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 1.3 PID_AURORA_B_PATHWAY Aurora B signaling
0.0 0.2 PID_IL5_PATHWAY IL5-mediated signaling events
0.0 0.3 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.0 0.5 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.0 0.5 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.0 0.7 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.3 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.1 PID_MYC_PATHWAY C-MYC pathway
0.0 0.6 PID_SYNDECAN_4_PATHWAY Syndecan-4-mediated signaling events
0.0 0.3 PID_P38_ALPHA_BETA_PATHWAY Regulation of p38-alpha and p38-beta

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.3 REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.3 REACTOME_ADENYLATE_CYCLASE_ACTIVATING_PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.4 REACTOME_ASSOCIATION_OF_LICENSING_FACTORS_WITH_THE_PRE_REPLICATIVE_COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 0.8 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.0 0.4 REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 1.4 REACTOME_INTEGRIN_ALPHAIIB_BETA3_SIGNALING Genes involved in Integrin alphaIIb beta3 signaling
0.0 0.1 REACTOME_PLATELET_AGGREGATION_PLUG_FORMATION Genes involved in Platelet Aggregation (Plug Formation)
0.0 0.3 REACTOME_XENOBIOTICS Genes involved in Xenobiotics
0.0 0.3 REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.3 REACTOME_DOPAMINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.0 0.2 REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.6 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.3 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.3 REACTOME_HYALURONAN_METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.2 REACTOME_SIGNALING_BY_FGFR3_MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 0.4 REACTOME_GABA_A_RECEPTOR_ACTIVATION Genes involved in GABA A receptor activation
0.0 0.5 REACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.2 REACTOME_ROLE_OF_SECOND_MESSENGERS_IN_NETRIN1_SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.2 REACTOME_IKK_COMPLEX_RECRUITMENT_MEDIATED_BY_RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.3 REACTOME_G0_AND_EARLY_G1 Genes involved in G0 and Early G1
0.0 0.4 REACTOME_SIGNALING_BY_BMP Genes involved in Signaling by BMP
0.0 0.4 REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.4 REACTOME_ACTIVATION_OF_THE_PRE_REPLICATIVE_COMPLEX Genes involved in Activation of the pre-replicative complex
0.0 0.1 REACTOME_ERKS_ARE_INACTIVATED Genes involved in ERKs are inactivated
0.0 0.1 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha