Motif ID: NFATC1
Z-value: 1.112

Transcription factors associated with NFATC1:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
NFATC1 | ENSG00000131196.13 | NFATC1 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
NFATC1 | hg19_v2_chr18_+_77155856_77155939 | 0.59 | 2.2e-03 | Click! |
Top targets:
Showing 1 to 20 of 200 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 138 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
4.1 | 16.5 | GO:2000768 | glomerular parietal epithelial cell differentiation(GO:0072139) positive regulation of nephron tubule epithelial cell differentiation(GO:2000768) |
2.9 | 11.6 | GO:0002503 | peptide antigen assembly with MHC class II protein complex(GO:0002503) |
0.0 | 8.3 | GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156) |
0.6 | 8.2 | GO:0048251 | elastic fiber assembly(GO:0048251) |
0.3 | 7.6 | GO:0019800 | peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800) |
2.0 | 6.0 | GO:0010430 | fatty acid omega-oxidation(GO:0010430) |
0.0 | 4.8 | GO:0065004 | protein-DNA complex assembly(GO:0065004) |
0.2 | 3.9 | GO:0072189 | ureter development(GO:0072189) |
1.1 | 3.4 | GO:0042495 | detection of triacyl bacterial lipopeptide(GO:0042495) detection of bacterial lipopeptide(GO:0070340) |
0.0 | 3.3 | GO:1904668 | positive regulation of ubiquitin protein ligase activity(GO:1904668) |
0.2 | 3.0 | GO:0036159 | inner dynein arm assembly(GO:0036159) |
0.0 | 2.9 | GO:0006904 | vesicle docking involved in exocytosis(GO:0006904) |
0.1 | 2.4 | GO:0007379 | segment specification(GO:0007379) |
0.1 | 2.2 | GO:0052695 | cellular glucuronidation(GO:0052695) |
0.2 | 2.0 | GO:0042699 | follicle-stimulating hormone signaling pathway(GO:0042699) |
0.0 | 1.8 | GO:0007223 | Wnt signaling pathway, calcium modulating pathway(GO:0007223) |
0.2 | 1.7 | GO:0072513 | positive regulation of secondary heart field cardioblast proliferation(GO:0072513) |
0.0 | 1.6 | GO:0016575 | histone deacetylation(GO:0016575) |
0.1 | 1.5 | GO:0097094 | craniofacial suture morphogenesis(GO:0097094) |
0.1 | 1.5 | GO:0036315 | cellular response to sterol(GO:0036315) |
Gene overrepresentation in cellular_component category:
Showing 1 to 20 of 38 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.9 | 16.5 | GO:0042622 | photoreceptor outer segment membrane(GO:0042622) |
0.6 | 11.6 | GO:0042613 | MHC class II protein complex(GO:0042613) |
0.8 | 8.2 | GO:0071953 | elastic fiber(GO:0071953) |
0.0 | 5.9 | GO:0032993 | protein-DNA complex(GO:0032993) |
0.1 | 4.8 | GO:0009925 | basal plasma membrane(GO:0009925) |
0.0 | 3.7 | GO:0005923 | bicellular tight junction(GO:0005923) |
1.1 | 3.4 | GO:0035354 | Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354) |
0.0 | 3.0 | GO:0036126 | sperm flagellum(GO:0036126) |
0.1 | 2.9 | GO:0000145 | exocyst(GO:0000145) |
0.1 | 2.0 | GO:0031143 | pseudopodium(GO:0031143) |
0.0 | 2.0 | GO:0017053 | transcriptional repressor complex(GO:0017053) |
0.1 | 1.7 | GO:0005589 | collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647) |
0.0 | 1.6 | GO:0008023 | transcription elongation factor complex(GO:0008023) |
0.0 | 1.4 | GO:0045171 | intercellular bridge(GO:0045171) |
0.0 | 1.3 | GO:0101003 | ficolin-1-rich granule membrane(GO:0101003) |
0.2 | 1.2 | GO:0098575 | lumenal side of lysosomal membrane(GO:0098575) |
0.1 | 1.2 | GO:0044300 | cerebellar mossy fiber(GO:0044300) |
0.0 | 1.1 | GO:0030286 | dynein complex(GO:0030286) |
0.2 | 0.8 | GO:0002169 | 3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202) |
0.0 | 0.8 | GO:0035102 | PRC1 complex(GO:0035102) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 80 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 17.0 | GO:0042805 | actinin binding(GO:0042805) |
0.4 | 12.8 | GO:0023026 | MHC class II protein complex binding(GO:0023026) |
0.0 | 11.0 | GO:0008022 | protein C-terminus binding(GO:0008022) |
1.5 | 6.0 | GO:0004031 | aldehyde oxidase activity(GO:0004031) |
0.2 | 5.9 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
0.4 | 5.3 | GO:0001011 | transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087) |
0.5 | 3.9 | GO:0010997 | anaphase-promoting complex binding(GO:0010997) |
0.8 | 3.4 | GO:0035663 | Toll-like receptor 2 binding(GO:0035663) |
0.1 | 2.2 | GO:0015020 | glucuronosyltransferase activity(GO:0015020) |
0.1 | 2.1 | GO:0005328 | neurotransmitter:sodium symporter activity(GO:0005328) |
0.7 | 2.0 | GO:0031896 | V2 vasopressin receptor binding(GO:0031896) |
0.0 | 2.0 | GO:0004860 | protein kinase inhibitor activity(GO:0004860) |
0.1 | 1.9 | GO:0004000 | adenosine deaminase activity(GO:0004000) |
0.0 | 1.8 | GO:0000983 | transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983) |
0.2 | 1.5 | GO:0008142 | oxysterol binding(GO:0008142) |
0.2 | 1.4 | GO:0000298 | endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848) |
0.2 | 1.4 | GO:0001225 | RNA polymerase II transcription coactivator binding(GO:0001225) |
0.1 | 1.4 | GO:0017081 | chloride channel regulator activity(GO:0017081) |
0.0 | 1.4 | GO:0005154 | epidermal growth factor receptor binding(GO:0005154) |
0.0 | 1.4 | GO:0004004 | ATP-dependent RNA helicase activity(GO:0004004) |
Gene overrepresentation in C2:CP category:
Showing 1 to 20 of 22 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 8.1 | PID_HNF3A_PATHWAY | FOXA1 transcription factor network |
0.1 | 7.7 | PID_IL12_STAT4_PATHWAY | IL12 signaling mediated by STAT4 |
0.1 | 6.5 | NABA_PROTEOGLYCANS | Genes encoding proteoglycans |
0.0 | 5.9 | PID_AR_PATHWAY | Coregulation of Androgen receptor activity |
0.0 | 3.7 | PID_INSULIN_PATHWAY | Insulin Pathway |
0.1 | 3.4 | PID_TOLL_ENDOGENOUS_PATHWAY | Endogenous TLR signaling |
0.1 | 2.0 | PID_IL8_CXCR1_PATHWAY | IL8- and CXCR1-mediated signaling events |
0.0 | 2.0 | PID_AJDISS_2PATHWAY | Posttranslational regulation of adherens junction stability and dissassembly |
0.0 | 1.8 | PID_RB_1PATHWAY | Regulation of retinoblastoma protein |
0.0 | 1.7 | PID_CD8_TCR_DOWNSTREAM_PATHWAY | Downstream signaling in naïve CD8+ T cells |
0.0 | 1.4 | PID_BETA_CATENIN_NUC_PATHWAY | Regulation of nuclear beta catenin signaling and target gene transcription |
0.0 | 1.2 | PID_ANGIOPOIETIN_RECEPTOR_PATHWAY | Angiopoietin receptor Tie2-mediated signaling |
0.0 | 1.2 | PID_E2F_PATHWAY | E2F transcription factor network |
0.0 | 1.1 | PID_IL23_PATHWAY | IL23-mediated signaling events |
0.0 | 0.9 | PID_ARF6_PATHWAY | Arf6 signaling events |
0.0 | 0.8 | ST_GA12_PATHWAY | G alpha 12 Pathway |
0.0 | 0.7 | PID_HIF2PATHWAY | HIF-2-alpha transcription factor network |
0.0 | 0.7 | PID_ATM_PATHWAY | ATM pathway |
0.0 | 0.5 | PID_CIRCADIAN_PATHWAY | Circadian rhythm pathway |
0.0 | 0.3 | PID_ALK2_PATHWAY | ALK2 signaling events |
Gene overrepresentation in C2:CP:REACTOME category:
Showing 1 to 20 of 38 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.4 | 6.0 | REACTOME_ETHANOL_OXIDATION | Genes involved in Ethanol oxidation |
0.1 | 5.1 | REACTOME_MYOGENESIS | Genes involved in Myogenesis |
0.1 | 4.2 | REACTOME_BETA_DEFENSINS | Genes involved in Beta defensins |
0.1 | 3.4 | REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING | Genes involved in Insulin Synthesis and Processing |
0.1 | 3.2 | REACTOME_LYSOSOME_VESICLE_BIOGENESIS | Genes involved in Lysosome Vesicle Biogenesis |
0.0 | 2.9 | REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION | Genes involved in MHC class II antigen presentation |
0.1 | 2.2 | REACTOME_GLUCURONIDATION | Genes involved in Glucuronidation |
0.1 | 2.1 | REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS | Genes involved in Na+/Cl- dependent neurotransmitter transporters |
0.1 | 1.8 | REACTOME_CS_DS_DEGRADATION | Genes involved in CS/DS degradation |
0.0 | 1.6 | REACTOME_TIGHT_JUNCTION_INTERACTIONS | Genes involved in Tight junction interactions |
0.0 | 1.6 | REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
0.0 | 1.4 | REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA | Genes involved in Circadian Repression of Expression by REV-ERBA |
0.0 | 1.4 | REACTOME_CHOLESTEROL_BIOSYNTHESIS | Genes involved in Cholesterol biosynthesis |
0.0 | 1.3 | REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_3_PROMOTER | Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter |
0.1 | 1.0 | REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS | Genes involved in Tandem pore domain potassium channels |
0.1 | 0.9 | REACTOME_HORMONE_LIGAND_BINDING_RECEPTORS | Genes involved in Hormone ligand-binding receptors |
0.0 | 0.9 | REACTOME_DOUBLE_STRAND_BREAK_REPAIR | Genes involved in Double-Strand Break Repair |
0.0 | 0.8 | REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM | Genes involved in Branched-chain amino acid catabolism |
0.0 | 0.8 | REACTOME_POST_TRANSLATIONAL_MODIFICATION_SYNTHESIS_OF_GPI_ANCHORED_PROTEINS | Genes involved in Post-translational modification: synthesis of GPI-anchored proteins |
0.0 | 0.7 | REACTOME_XENOBIOTICS | Genes involved in Xenobiotics |