Motif ID: NOTO_VSX2_DLX2_DLX6_NKX6-1

Z-value: 0.632


Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
DLX2hg19_v2_chr2_-_172967621_1729676370.537.2e-03Click!
DLX6hg19_v2_chr7_+_96635277_96635301,
hg19_v2_chr7_+_96634850_96634874
-0.262.2e-01Click!
NKX6-1hg19_v2_chr4_-_85419603_854196030.145.1e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of NOTO_VSX2_DLX2_DLX6_NKX6-1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr13_+_36050881 3.085 ENST00000537702.1
NBEA
neurobeachin
chr17_-_39203519 2.723 ENST00000542137.1
ENST00000391419.3
KRTAP2-1

keratin associated protein 2-1

chr6_-_87804815 2.321 ENST00000369582.2
CGA
glycoprotein hormones, alpha polypeptide
chr7_-_25268104 1.794 ENST00000222674.2
NPVF
neuropeptide VF precursor
chr1_-_183622442 1.621 ENST00000308641.4
APOBEC4
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 4 (putative)
chr8_-_10512569 1.385 ENST00000382483.3
RP1L1
retinitis pigmentosa 1-like 1
chr20_-_7921090 1.268 ENST00000378789.3
HAO1
hydroxyacid oxidase (glycolate oxidase) 1
chr6_-_76203345 1.242 ENST00000393004.2
FILIP1
filamin A interacting protein 1
chr4_-_138453606 1.224 ENST00000412923.2
ENST00000344876.4
ENST00000507846.1
ENST00000510305.1
PCDH18



protocadherin 18



chr6_-_76203454 1.211 ENST00000237172.7
FILIP1
filamin A interacting protein 1
chr2_-_68052694 1.157 ENST00000457448.1
AC010987.6
AC010987.6
chr2_-_145278475 1.138 ENST00000558170.2
ZEB2
zinc finger E-box binding homeobox 2
chr11_-_31531121 1.101 ENST00000532287.1
ENST00000526776.1
ENST00000534812.1
ENST00000529749.1
ENST00000278200.1
ENST00000530023.1
ENST00000533642.1
IMMP1L






IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae)






chr20_-_50419055 1.098 ENST00000217086.4
SALL4
spalt-like transcription factor 4
chr12_-_16761007 0.983 ENST00000354662.1
ENST00000441439.2
LMO3

LIM domain only 3 (rhombotin-like 2)

chr16_+_53133070 0.976 ENST00000565832.1
CHD9
chromodomain helicase DNA binding protein 9
chr16_-_28621353 0.940 ENST00000567512.1
SULT1A1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr12_+_54378923 0.940 ENST00000303460.4
HOXC10
homeobox C10
chr14_-_92413727 0.896 ENST00000267620.10
FBLN5
fibulin 5
chr1_+_183774240 0.890 ENST00000360851.3
RGL1
ral guanine nucleotide dissociation stimulator-like 1
chr1_-_150738261 0.888 ENST00000448301.2
ENST00000368985.3
CTSS

cathepsin S

chr9_-_215744 0.869 ENST00000382387.2
C9orf66
chromosome 9 open reading frame 66
chr14_-_54423529 0.860 ENST00000245451.4
ENST00000559087.1
BMP4

bone morphogenetic protein 4

chr4_+_71108300 0.851 ENST00000304954.3
CSN3
casein kappa
chr14_-_92413353 0.807 ENST00000556154.1
FBLN5
fibulin 5
chr8_-_72268968 0.802 ENST00000388740.3
EYA1
eyes absent homolog 1 (Drosophila)
chrX_-_73512411 0.784 ENST00000602576.1
ENST00000429124.1
FTX

FTX transcript, XIST regulator (non-protein coding)

chr8_-_72268889 0.779 ENST00000388742.4
EYA1
eyes absent homolog 1 (Drosophila)
chr1_+_244515930 0.773 ENST00000366537.1
ENST00000308105.4
C1orf100

chromosome 1 open reading frame 100

chr9_+_12693336 0.769 ENST00000381137.2
ENST00000388918.5
TYRP1

tyrosinase-related protein 1

chr4_-_25865159 0.747 ENST00000502949.1
ENST00000264868.5
ENST00000513691.1
ENST00000514872.1
SEL1L3



sel-1 suppressor of lin-12-like 3 (C. elegans)



chr3_+_111717600 0.721 ENST00000273368.4
TAGLN3
transgelin 3
chr3_+_111718036 0.720 ENST00000455401.2
TAGLN3
transgelin 3
chrX_-_44202857 0.711 ENST00000420999.1
EFHC2
EF-hand domain (C-terminal) containing 2
chr12_+_26348582 0.692 ENST00000535504.1
SSPN
sarcospan
chr3_+_111718173 0.668 ENST00000494932.1
TAGLN3
transgelin 3
chr5_-_24645078 0.661 ENST00000264463.4
CDH10
cadherin 10, type 2 (T2-cadherin)
chr3_+_111717511 0.653 ENST00000478951.1
ENST00000393917.2
TAGLN3

transgelin 3

chr19_-_7698599 0.632 ENST00000311069.5
PCP2
Purkinje cell protein 2
chr18_+_32173276 0.623 ENST00000591816.1
ENST00000588125.1
ENST00000598334.1
ENST00000588684.1
ENST00000554864.3
ENST00000399121.5
ENST00000595022.1
ENST00000269190.7
ENST00000399097.3
DTNA








dystrobrevin, alpha








chr11_-_40315640 0.620 ENST00000278198.2
LRRC4C
leucine rich repeat containing 4C
chr5_-_137475071 0.616 ENST00000265191.2
NME5
NME/NM23 family member 5
chr4_+_77356248 0.604 ENST00000296043.6
SHROOM3
shroom family member 3
chr20_-_50418947 0.583 ENST00000371539.3
SALL4
spalt-like transcription factor 4
chr7_-_130080977 0.580 ENST00000223208.5
CEP41
centrosomal protein 41kDa
chr17_-_10421853 0.575 ENST00000226207.5
MYH1
myosin, heavy chain 1, skeletal muscle, adult
chr1_+_61548374 0.573 ENST00000485903.2
ENST00000371185.2
ENST00000371184.2
NFIA


nuclear factor I/A


chr15_-_37393406 0.561 ENST00000338564.5
ENST00000558313.1
ENST00000340545.5
MEIS2


Meis homeobox 2


chr12_-_68696652 0.558 ENST00000539972.1
MDM1
Mdm1 nuclear protein homolog (mouse)
chr6_-_161695042 0.556 ENST00000366908.5
ENST00000366911.5
ENST00000366905.3
AGPAT4


1-acylglycerol-3-phosphate O-acyltransferase 4


chr17_-_39280419 0.530 ENST00000394014.1
KRTAP4-12
keratin associated protein 4-12
chr5_+_53751445 0.520 ENST00000302005.1
HSPB3
heat shock 27kDa protein 3
chr8_-_133637624 0.515 ENST00000522789.1
LRRC6
leucine rich repeat containing 6
chr13_-_36050819 0.513 ENST00000379919.4
MAB21L1
mab-21-like 1 (C. elegans)
chr20_-_50418972 0.513 ENST00000395997.3
SALL4
spalt-like transcription factor 4
chr5_-_96478466 0.508 ENST00000274382.4
LIX1
Lix1 homolog (chicken)
chr5_+_156696362 0.496 ENST00000377576.3
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr2_+_128403439 0.486 ENST00000544369.1
GPR17
G protein-coupled receptor 17
chr20_-_21494654 0.484 ENST00000377142.4
NKX2-2
NK2 homeobox 2
chr13_-_70682590 0.484 ENST00000377844.4
KLHL1
kelch-like family member 1
chr3_+_2933893 0.478 ENST00000397459.2
CNTN4
contactin 4
chr2_+_128403720 0.474 ENST00000272644.3
GPR17
G protein-coupled receptor 17
chr17_-_39165366 0.468 ENST00000391588.1
KRTAP3-1
keratin associated protein 3-1
chr4_-_177116772 0.468 ENST00000280191.2
SPATA4
spermatogenesis associated 4
chr7_+_99717230 0.462 ENST00000262932.3
CNPY4
canopy FGF signaling regulator 4
chr5_-_13944652 0.455 ENST00000265104.4
DNAH5
dynein, axonemal, heavy chain 5
chr6_-_161695074 0.448 ENST00000457520.2
ENST00000366906.5
ENST00000320285.4
AGPAT4


1-acylglycerol-3-phosphate O-acyltransferase 4


chr19_-_56110859 0.446 ENST00000221665.3
ENST00000592585.1
FIZ1

FLT3-interacting zinc finger 1

chr6_-_76072719 0.438 ENST00000370020.1
FILIP1
filamin A interacting protein 1
chr11_+_124481361 0.438 ENST00000284288.2
PANX3
pannexin 3
chr6_+_135502501 0.436 ENST00000527615.1
ENST00000420123.2
ENST00000525369.1
ENST00000528774.1
ENST00000534121.1
ENST00000534044.1
ENST00000533624.1
MYB






v-myb avian myeloblastosis viral oncogene homolog






chr17_-_77924627 0.426 ENST00000572862.1
ENST00000573782.1
ENST00000574427.1
ENST00000570373.1
ENST00000340848.7
ENST00000576768.1
TBC1D16





TBC1 domain family, member 16





chr11_-_129062093 0.417 ENST00000310343.9
ARHGAP32
Rho GTPase activating protein 32
chrX_-_46187069 0.405 ENST00000446884.1
RP1-30G7.2
RP1-30G7.2
chr12_-_52946923 0.399 ENST00000267119.5
KRT71
keratin 71
chr3_-_114477787 0.392 ENST00000464560.1
ZBTB20
zinc finger and BTB domain containing 20
chr1_+_61548225 0.391 ENST00000371187.3
NFIA
nuclear factor I/A
chr3_-_141747950 0.390 ENST00000497579.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr8_+_50824233 0.381 ENST00000522124.1
SNTG1
syntrophin, gamma 1
chr13_-_84456527 0.378 ENST00000377084.2
SLITRK1
SLIT and NTRK-like family, member 1
chr3_+_69928256 0.378 ENST00000394355.2
MITF
microphthalmia-associated transcription factor
chr19_-_7697857 0.377 ENST00000598935.1
PCP2
Purkinje cell protein 2
chr12_-_16759711 0.375 ENST00000447609.1
LMO3
LIM domain only 3 (rhombotin-like 2)
chr18_-_47792851 0.373 ENST00000398545.4
CCDC11
coiled-coil domain containing 11
chr17_+_68071389 0.371 ENST00000283936.1
ENST00000392671.1
KCNJ16

potassium inwardly-rectifying channel, subfamily J, member 16

chr7_+_23286182 0.363 ENST00000258733.4
ENST00000381990.2
ENST00000409458.3
ENST00000539136.1
ENST00000453162.2
GPNMB




glycoprotein (transmembrane) nmb




chr1_+_180601139 0.363 ENST00000367590.4
ENST00000367589.3
XPR1

xenotropic and polytropic retrovirus receptor 1

chr18_-_53089723 0.358 ENST00000561992.1
ENST00000562512.2
TCF4

transcription factor 4

chr11_-_33913708 0.354 ENST00000257818.2
LMO2
LIM domain only 2 (rhombotin-like 1)
chr21_+_17442799 0.352 ENST00000602580.1
ENST00000458468.1
ENST00000602935.1
LINC00478


long intergenic non-protein coding RNA 478


chr6_+_39760129 0.351 ENST00000274867.4
DAAM2
dishevelled associated activator of morphogenesis 2
chr10_-_102989551 0.349 ENST00000370193.2
LBX1
ladybird homeobox 1
chr3_-_114477962 0.346 ENST00000471418.1
ZBTB20
zinc finger and BTB domain containing 20
chr4_-_123542224 0.345 ENST00000264497.3
IL21
interleukin 21
chr7_+_97361388 0.344 ENST00000350485.4
ENST00000346867.4
TAC1

tachykinin, precursor 1

chr11_+_71900703 0.343 ENST00000393681.2
FOLR1
folate receptor 1 (adult)
chr8_-_109799793 0.341 ENST00000297459.3
TMEM74
transmembrane protein 74
chr13_-_46716969 0.341 ENST00000435666.2
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chrX_-_117119243 0.338 ENST00000539496.1
ENST00000469946.1
KLHL13

kelch-like family member 13

chr11_+_71900572 0.337 ENST00000312293.4
FOLR1
folate receptor 1 (adult)
chr4_-_74486109 0.334 ENST00000395777.2
RASSF6
Ras association (RalGDS/AF-6) domain family member 6
chr6_-_22297730 0.332 ENST00000306482.1
PRL
prolactin
chr4_+_71458012 0.330 ENST00000449493.2
AMBN
ameloblastin (enamel matrix protein)
chr17_+_39261584 0.314 ENST00000391415.1
KRTAP4-9
keratin associated protein 4-9
chr1_-_94586651 0.311 ENST00000535735.1
ENST00000370225.3
ABCA4

ATP-binding cassette, sub-family A (ABC1), member 4

chr4_+_71494461 0.310 ENST00000396073.3
ENAM
enamelin
chr1_+_61547405 0.309 ENST00000371189.4
NFIA
nuclear factor I/A
chr7_+_73442487 0.304 ENST00000380575.4
ENST00000380584.4
ENST00000458204.1
ENST00000357036.5
ENST00000417091.1
ENST00000429192.1
ENST00000442310.1
ENST00000380553.4
ENST00000380576.5
ENST00000428787.1
ENST00000320399.6
ELN










elastin










chr11_-_26593779 0.296 ENST00000529533.1
MUC15
mucin 15, cell surface associated
chr4_-_41884582 0.294 ENST00000499082.2
LINC00682
long intergenic non-protein coding RNA 682
chr7_+_116660246 0.294 ENST00000434836.1
ENST00000393443.1
ENST00000465133.1
ENST00000477742.1
ENST00000393447.4
ENST00000393444.3
ST7





suppression of tumorigenicity 7





chr12_-_86650045 0.289 ENST00000604798.1
MGAT4C
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr1_+_61547894 0.286 ENST00000403491.3
NFIA
nuclear factor I/A
chr2_-_203735586 0.285 ENST00000454326.1
ENST00000432273.1
ENST00000450143.1
ENST00000411681.1
ICA1L



islet cell autoantigen 1,69kDa-like



chr11_-_121986923 0.279 ENST00000560104.1
BLID
BH3-like motif containing, cell death inducer
chr20_+_11008408 0.274 ENST00000378252.1
C20orf187
chromosome 20 open reading frame 187
chr17_-_40337470 0.268 ENST00000293330.1
HCRT
hypocretin (orexin) neuropeptide precursor
chr15_+_76352178 0.268 ENST00000388942.3
C15orf27
chromosome 15 open reading frame 27
chr21_-_32253874 0.267 ENST00000332378.4
KRTAP11-1
keratin associated protein 11-1
chr9_+_130026756 0.264 ENST00000314904.5
ENST00000373387.4
GARNL3

GTPase activating Rap/RanGAP domain-like 3

chr2_+_216946589 0.263 ENST00000433112.1
ENST00000454545.1
ENST00000437356.2
ENST00000295658.4
ENST00000455479.1
ENST00000406027.2
TMEM169





transmembrane protein 169





chr17_+_59489112 0.263 ENST00000335108.2
C17orf82
chromosome 17 open reading frame 82
chr4_+_159727272 0.261 ENST00000379346.3
FNIP2
folliculin interacting protein 2
chr3_+_113616317 0.261 ENST00000440446.2
ENST00000488680.1
GRAMD1C

GRAM domain containing 1C

chr14_-_69261310 0.258 ENST00000336440.3
ZFP36L1
ZFP36 ring finger protein-like 1
chr3_+_120626919 0.257 ENST00000273666.6
ENST00000471454.1
ENST00000472879.1
ENST00000497029.1
ENST00000492541.1
STXBP5L




syntaxin binding protein 5-like




chr6_-_9933500 0.257 ENST00000492169.1
OFCC1
orofacial cleft 1 candidate 1
chr1_-_48937838 0.256 ENST00000371847.3
SPATA6
spermatogenesis associated 6
chr13_-_41593425 0.251 ENST00000239882.3
ELF1
E74-like factor 1 (ets domain transcription factor)
chr4_+_41614909 0.249 ENST00000509454.1
ENST00000396595.3
ENST00000381753.4
LIMCH1


LIM and calponin homology domains 1


chr21_-_31538971 0.248 ENST00000286808.3
CLDN17
claudin 17
chrX_+_72783026 0.248 ENST00000373504.6
ENST00000373502.5
CHIC1

cysteine-rich hydrophobic domain 1

chr12_+_20963647 0.248 ENST00000381545.3
SLCO1B3
solute carrier organic anion transporter family, member 1B3
chr11_-_102496063 0.248 ENST00000260228.2
MMP20
matrix metallopeptidase 20
chr7_+_73442422 0.241 ENST00000358929.4
ENST00000431562.1
ENST00000320492.7
ENST00000438906.1
ELN



elastin



chr12_+_41831485 0.239 ENST00000539469.2
ENST00000298919.7
PDZRN4

PDZ domain containing ring finger 4

chr17_-_72527605 0.238 ENST00000392621.1
ENST00000314401.3
CD300LB

CD300 molecule-like family member b

chr12_+_20963632 0.237 ENST00000540853.1
ENST00000261196.2
SLCO1B3

solute carrier organic anion transporter family, member 1B3

chr2_-_216946500 0.236 ENST00000265322.7
PECR
peroxisomal trans-2-enoyl-CoA reductase
chrX_-_10851762 0.235 ENST00000380785.1
ENST00000380787.1
MID1

midline 1 (Opitz/BBB syndrome)

chr2_+_162272605 0.235 ENST00000389554.3
TBR1
T-box, brain, 1
chr6_+_5261225 0.234 ENST00000324331.6
FARS2
phenylalanyl-tRNA synthetase 2, mitochondrial
chr3_+_173116225 0.234 ENST00000457714.1
NLGN1
neuroligin 1
chr6_-_111804905 0.232 ENST00000358835.3
ENST00000435970.1
REV3L

REV3-like, polymerase (DNA directed), zeta, catalytic subunit

chr5_+_69321074 0.231 ENST00000380751.5
ENST00000380750.3
ENST00000503931.1
ENST00000506542.1
SERF1B



small EDRK-rich factor 1B (centromeric)



chr9_+_2159850 0.231 ENST00000416751.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr20_+_52105495 0.230 ENST00000439873.2
AL354993.1
Cell growth-inhibiting protein 7; HCG1784586; Uncharacterized protein
chr7_-_92855762 0.229 ENST00000453812.2
ENST00000394468.2
HEPACAM2

HEPACAM family member 2

chr3_-_114790179 0.228 ENST00000462705.1
ZBTB20
zinc finger and BTB domain containing 20
chr11_+_15136462 0.225 ENST00000379556.3
ENST00000424273.1
INSC

inscuteable homolog (Drosophila)

chr8_-_72274095 0.225 ENST00000303824.7
EYA1
eyes absent homolog 1 (Drosophila)
chr6_-_33160231 0.223 ENST00000395194.1
ENST00000457788.1
ENST00000341947.2
ENST00000357486.1
ENST00000374714.1
ENST00000374713.1
ENST00000395197.1
ENST00000374712.1
ENST00000361917.1
ENST00000374708.4
COL11A2









collagen, type XI, alpha 2









chr7_+_141478242 0.222 ENST00000247881.2
TAS2R4
taste receptor, type 2, member 4
chr2_+_179184955 0.222 ENST00000315022.2
OSBPL6
oxysterol binding protein-like 6
chr9_-_124989804 0.220 ENST00000373755.2
ENST00000373754.2
LHX6

LIM homeobox 6

chr3_+_157154578 0.219 ENST00000295927.3
PTX3
pentraxin 3, long
chr16_-_28621312 0.219 ENST00000314752.7
SULT1A1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr15_+_41913690 0.219 ENST00000563576.1
MGA
MGA, MAX dimerization protein
chr1_+_40713573 0.217 ENST00000372766.3
TMCO2
transmembrane and coiled-coil domains 2
chr8_+_121137333 0.214 ENST00000309791.4
ENST00000297848.3
ENST00000247781.3
COL14A1


collagen, type XIV, alpha 1


chr10_+_17270214 0.213 ENST00000544301.1
VIM
vimentin
chrX_+_68835911 0.212 ENST00000525810.1
ENST00000527388.1
ENST00000374553.2
ENST00000374552.4
ENST00000338901.3
ENST00000524573.1
EDA





ectodysplasin A





chr11_-_26593649 0.210 ENST00000455601.2
MUC15
mucin 15, cell surface associated
chr10_-_62332357 0.210 ENST00000503366.1
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr4_-_105416039 0.208 ENST00000394767.2
CXXC4
CXXC finger protein 4
chr4_+_66536248 0.207 ENST00000514260.1
ENST00000507117.1
RP11-807H7.1

RP11-807H7.1

chr5_-_35195338 0.207 ENST00000509839.1
PRLR
prolactin receptor
chr1_-_227505289 0.207 ENST00000366765.3
CDC42BPA
CDC42 binding protein kinase alpha (DMPK-like)
chr2_-_190927447 0.204 ENST00000260950.4
MSTN
myostatin
chr1_+_214161272 0.204 ENST00000498508.2
ENST00000366958.4
PROX1

prospero homeobox 1

chr6_-_76782371 0.203 ENST00000369950.3
ENST00000369963.3
IMPG1

interphotoreceptor matrix proteoglycan 1

chrX_+_22050546 0.202 ENST00000379374.4
PHEX
phosphate regulating endopeptidase homolog, X-linked
chr7_+_107110488 0.201 ENST00000304402.4
GPR22
G protein-coupled receptor 22
chr4_+_169418195 0.201 ENST00000261509.6
ENST00000335742.7
PALLD

palladin, cytoskeletal associated protein

chr4_-_74486347 0.199 ENST00000342081.3
RASSF6
Ras association (RalGDS/AF-6) domain family member 6
chr21_+_17443434 0.199 ENST00000400178.2
LINC00478
long intergenic non-protein coding RNA 478
chr8_+_55528627 0.199 ENST00000220676.1
RP1
retinitis pigmentosa 1 (autosomal dominant)
chr5_+_133562095 0.198 ENST00000602919.1
CTD-2410N18.3
CTD-2410N18.3
chr2_+_234959376 0.196 ENST00000425558.1
SPP2
secreted phosphoprotein 2, 24kDa
chr13_+_108922228 0.196 ENST00000542136.1
TNFSF13B
tumor necrosis factor (ligand) superfamily, member 13b
chr9_-_124990680 0.196 ENST00000541397.2
ENST00000560485.1
LHX6

LIM homeobox 6

chr1_+_44679113 0.195 ENST00000361745.6
ENST00000446292.1
ENST00000440641.1
ENST00000436069.1
ENST00000437511.1
DMAP1




DNA methyltransferase 1 associated protein 1




chr4_-_138453559 0.191 ENST00000511115.1
PCDH18
protocadherin 18
chr21_+_17909594 0.190 ENST00000441820.1
ENST00000602280.1
LINC00478

long intergenic non-protein coding RNA 478

chr13_-_88323218 0.190 ENST00000436290.2
ENST00000453832.2
ENST00000606590.1
MIR4500HG


MIR4500 host gene (non-protein coding)


chr17_-_39211463 0.190 ENST00000542910.1
ENST00000398477.1
KRTAP2-2

keratin associated protein 2-2

chr5_-_88119580 0.190 ENST00000539796.1
MEF2C
myocyte enhancer factor 2C
chr7_+_114055052 0.189 ENST00000462331.1
ENST00000408937.3
ENST00000403559.4
ENST00000350908.4
ENST00000393498.2
ENST00000393495.3
ENST00000378237.3
ENST00000393489.3
FOXP2







forkhead box P2







chr2_+_183943464 0.188 ENST00000354221.4
DUSP19
dual specificity phosphatase 19
chr3_-_27763803 0.187 ENST00000449599.1
EOMES
eomesodermin
chr10_+_111765562 0.186 ENST00000360162.3
ADD3
adducin 3 (gamma)
chr13_-_36788718 0.185 ENST00000317764.6
ENST00000379881.3
SOHLH2

spermatogenesis and oogenesis specific basic helix-loop-helix 2

chr6_-_32908792 0.182 ENST00000418107.2
HLA-DMB
major histocompatibility complex, class II, DM beta
chr6_-_39693111 0.181 ENST00000373215.3
ENST00000538893.1
ENST00000287152.7
ENST00000373216.3
KIF6



kinesin family member 6



chr3_-_112360116 0.181 ENST00000206423.3
ENST00000439685.2
CCDC80

coiled-coil domain containing 80

chr5_-_160279207 0.181 ENST00000327245.5
ATP10B
ATPase, class V, type 10B
chr5_-_159827033 0.181 ENST00000523213.1
C5orf54
chromosome 5 open reading frame 54
chr14_-_98444461 0.180 ENST00000499006.2
C14orf64
chromosome 14 open reading frame 64
chr10_-_1779663 0.178 ENST00000381312.1
ADARB2
adenosine deaminase, RNA-specific, B2 (non-functional)
chr8_-_139926236 0.176 ENST00000303045.6
ENST00000435777.1
COL22A1

collagen, type XXII, alpha 1


Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:1905072 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.2 0.7 GO:0003147 neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713)
0.2 1.4 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.2 1.9 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.2 0.6 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.2 1.1 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.2 1.9 GO:0032277 negative regulation of gonadotropin secretion(GO:0032277)
0.2 0.3 GO:2000854 positive regulation of corticosterone secretion(GO:2000854)
0.2 0.5 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.2 0.8 GO:0048023 positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.1 2.2 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.1 0.4 GO:1904899 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.1 1.8 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 1.5 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.1 0.9 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.1 0.1 GO:0060738 epithelial-mesenchymal signaling involved in prostate gland development(GO:0060738)
0.1 0.2 GO:1902725 negative regulation of satellite cell differentiation(GO:1902725)
0.1 0.4 GO:0072658 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 0.3 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
0.1 0.3 GO:1904580 regulation of intracellular mRNA localization(GO:1904580) positive regulation of intracellular mRNA localization(GO:1904582)
0.1 0.9 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.1 0.2 GO:0099543 retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by trans-synaptic complex(GO:0099545)
0.1 1.6 GO:0072189 ureter development(GO:0072189)
0.1 0.2 GO:0098582 innate vocalization behavior(GO:0098582)
0.1 0.2 GO:2001190 positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190)
0.1 1.0 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.1 0.2 GO:0090425 hepatocyte cell migration(GO:0002194) otic placode formation(GO:0043049) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.1 0.6 GO:0018095 protein polyglutamylation(GO:0018095)
0.1 0.5 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.1 0.7 GO:0006228 UTP biosynthetic process(GO:0006228)
0.1 1.3 GO:0006068 ethanol catabolic process(GO:0006068)
0.1 1.0 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0 0.5 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0 0.2 GO:0003172 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.0 0.5 GO:0048664 neuron fate determination(GO:0048664)
0.0 0.2 GO:0031296 positive regulation of germinal center formation(GO:0002636) B cell costimulation(GO:0031296)
0.0 1.2 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 0.3 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.0 0.7 GO:0045176 apical protein localization(GO:0045176)
0.0 0.2 GO:0060023 soft palate development(GO:0060023)
0.0 0.1 GO:1904640 response to methionine(GO:1904640)
0.0 0.6 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.0 0.2 GO:0061153 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.0 0.2 GO:1904383 response to sodium phosphate(GO:1904383)
0.0 1.9 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.4 GO:0034214 protein hexamerization(GO:0034214)
0.0 1.9 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.0 0.2 GO:0021764 amygdala development(GO:0021764)
0.0 0.3 GO:0071461 cellular response to redox state(GO:0071461)
0.0 0.4 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0 0.2 GO:0052199 negative regulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052199)
0.0 0.2 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.2 GO:0038161 prolactin signaling pathway(GO:0038161)
0.0 0.2 GO:0015692 lead ion transport(GO:0015692)
0.0 0.2 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.1 GO:0061743 motor learning(GO:0061743)
0.0 0.3 GO:0002414 immunoglobulin transcytosis in epithelial cells(GO:0002414)
0.0 0.5 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.0 GO:0021979 hypothalamus cell differentiation(GO:0021979)
0.0 0.1 GO:0051958 methotrexate transport(GO:0051958)
0.0 0.3 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 0.2 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.0 0.4 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.0 0.2 GO:0060437 lung growth(GO:0060437)
0.0 0.1 GO:0007113 endomitotic cell cycle(GO:0007113)
0.0 0.1 GO:1904245 regulation of polynucleotide adenylyltransferase activity(GO:1904245) positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
0.0 0.1 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.1 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0 0.1 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.0 0.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.1 GO:0010908 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.0 0.1 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.0 0.2 GO:0060020 Bergmann glial cell differentiation(GO:0060020)
0.0 0.3 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.6 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 1.0 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.2 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.0 0.1 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.0 0.1 GO:0002018 renin-angiotensin regulation of aldosterone production(GO:0002018) phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.0 0.1 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.0 0.3 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0 0.1 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.0 0.1 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.0 0.1 GO:0044245 polysaccharide digestion(GO:0044245)
0.0 0.0 GO:0060355 positive regulation of cell adhesion molecule production(GO:0060355)
0.0 0.1 GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.0 0.3 GO:0031647 regulation of protein stability(GO:0031647)
0.0 0.0 GO:0038188 cholecystokinin signaling pathway(GO:0038188)
0.0 0.4 GO:0044458 motile cilium assembly(GO:0044458)
0.0 0.1 GO:0010748 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
0.0 0.0 GO:0021730 trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740)
0.0 0.5 GO:0021680 cerebellar Purkinje cell layer development(GO:0021680)
0.0 0.1 GO:0050916 sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917)
0.0 0.1 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.1 GO:0010157 response to chlorate(GO:0010157)
0.0 0.1 GO:0071638 adiponectin secretion(GO:0070162) regulation of adiponectin secretion(GO:0070163) negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.0 0.1 GO:0006196 AMP catabolic process(GO:0006196)
0.0 0.9 GO:0007595 lactation(GO:0007595)
0.0 0.1 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.0 0.1 GO:0042492 gamma-delta T cell differentiation(GO:0042492)
0.0 0.2 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272)
0.0 0.4 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.0 0.1 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.5 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 0.1 GO:0014807 regulation of somitogenesis(GO:0014807)
0.0 0.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.0 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.0 0.4 GO:0001919 regulation of receptor recycling(GO:0001919)
0.0 0.2 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.0 GO:0009956 radial pattern formation(GO:0009956)
0.0 0.0 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.0 0.1 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0 0.5 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.1 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0 0.2 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.1 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.0 0.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.9 GO:0007585 respiratory gaseous exchange(GO:0007585)
0.0 0.2 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.1 GO:0008045 motor neuron axon guidance(GO:0008045)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.3 2.5 GO:0071953 elastic fiber(GO:0071953)
0.1 0.9 GO:0036021 endolysosome lumen(GO:0036021)
0.1 0.9 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.1 0.4 GO:0097224 sperm connecting piece(GO:0097224)
0.1 0.2 GO:0030934 anchoring collagen complex(GO:0030934)
0.0 0.5 GO:0036157 outer dynein arm(GO:0036157)
0.0 1.8 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.9 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.2 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.4 GO:0016013 syntrophin complex(GO:0016013)
0.0 3.1 GO:0045095 keratin filament(GO:0045095)
0.0 0.2 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.2 GO:0070826 paraferritin complex(GO:0070826)
0.0 0.8 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.1 GO:0060187 cell pole(GO:0060187)
0.0 0.1 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.1 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.0 0.1 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.0 0.6 GO:0032982 myosin filament(GO:0032982)
0.0 0.1 GO:0035841 new growing cell tip(GO:0035841)
0.0 0.2 GO:0070081 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.0 1.3 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 2.8 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.3 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.2 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.4 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.1 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 1.7 GO:0000792 heterochromatin(GO:0000792)
0.0 0.1 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.3 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.2 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 0.1 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.3 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.3 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 2.5 GO:0032993 protein-DNA complex(GO:0032993)
0.0 0.4 GO:0005921 gap junction(GO:0005921)
0.0 0.9 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 0.5 GO:0031904 endosome lumen(GO:0031904)
0.0 2.9 GO:0043209 myelin sheath(GO:0043209)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.2 1.3 GO:0050294 flavonol 3-sulfotransferase activity(GO:0047894) steroid sulfotransferase activity(GO:0050294)
0.2 0.7 GO:0061714 folic acid receptor activity(GO:0061714)
0.1 0.9 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1 0.3 GO:0005148 prolactin receptor binding(GO:0005148)
0.1 0.4 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.1 0.4 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.1 0.7 GO:0030021 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.1 0.2 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.1 0.3 GO:0019770 IgG receptor activity(GO:0019770)
0.1 0.9 GO:0039706 co-receptor binding(GO:0039706)
0.1 0.2 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.1 0.8 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.1 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.0 0.1 GO:0032767 copper-dependent protein binding(GO:0032767)
0.0 0.1 GO:0004613 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.0 0.3 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.2 GO:0004925 prolactin receptor activity(GO:0004925)
0.0 0.1 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.0 0.2 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.4 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.4 GO:0045545 syndecan binding(GO:0045545)
0.0 1.0 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 1.9 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines(GO:0016814)
0.0 0.5 GO:0032027 myosin light chain binding(GO:0032027)
0.0 0.2 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.0 0.2 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.1 GO:0015350 methotrexate transporter activity(GO:0015350)
0.0 1.0 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.1 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.6 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.1 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.0 0.1 GO:0005174 CD40 receptor binding(GO:0005174)
0.0 0.1 GO:0047237 glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047237)
0.0 0.1 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.0 0.2 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 1.0 GO:0001637 G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.0 1.2 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.3 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.7 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.1 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.0 0.4 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.1 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.1 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.2 GO:0046790 virion binding(GO:0046790)
0.0 0.2 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.5 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.2 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.0 0.7 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 0.0 GO:0004951 cholecystokinin receptor activity(GO:0004951)
0.0 0.2 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.1 GO:0019958 C-X-C chemokine binding(GO:0019958)
0.0 0.1 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 0.1 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.3 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.2 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.5 GO:0070888 E-box binding(GO:0070888)
0.0 0.3 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.4 GO:0070577 lysine-acetylated histone binding(GO:0070577)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.9 PID_REG_GR_PATHWAY Glucocorticoid receptor regulatory network
0.0 1.7 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.0 0.8 PID_P38_ALPHA_BETA_DOWNSTREAM_PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.7 NABA_COLLAGENS Genes encoding collagen proteins
0.0 0.7 PID_BMP_PATHWAY BMP receptor signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.4 REACTOME_ANDROGEN_BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.1 0.9 REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 1.0 REACTOME_P2Y_RECEPTORS Genes involved in P2Y receptors
0.0 1.3 REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 1.1 REACTOME_SYNTHESIS_OF_PA Genes involved in Synthesis of PA
0.0 0.7 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.5 REACTOME_TRANSPORT_OF_ORGANIC_ANIONS Genes involved in Transport of organic anions
0.0 0.5 REACTOME_PROLACTIN_RECEPTOR_SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.5 REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.1 REACTOME_DIGESTION_OF_DIETARY_CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.3 REACTOME_DESTABILIZATION_OF_MRNA_BY_BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 0.4 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins