Motif ID: NR1D1

Z-value: 0.438


Transcription factors associated with NR1D1:

Gene SymbolEntrez IDGene Name
NR1D1 ENSG00000126368.5 NR1D1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
NR1D1hg19_v2_chr17_-_38256973_382569900.019.8e-01Click!


Activity profile for motif NR1D1.

activity profile for motif NR1D1


Sorted Z-values histogram for motif NR1D1

Sorted Z-values for motif NR1D1



Network of associatons between targets according to the STRING database.



First level regulatory network of NR1D1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 126 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_+_20915409 1.244 ENST00000375071.3
 CDA
cytidine deaminase
chr2_+_127656486 0.644 ENST00000568484.1
ENST00000450035.1
 AC114783.1

Protein LOC339760

chr14_+_24540046 0.599 ENST00000397016.2
ENST00000537691.1
ENST00000560356.1
ENST00000558450.1
 CPNE6



copine VI (neuronal)



chr14_+_24540731 0.533 ENST00000558859.1
ENST00000559197.1
ENST00000560828.1
ENST00000216775.2
ENST00000560884.1
 CPNE6




copine VI (neuronal)




chr1_-_111991850 0.458 ENST00000411751.2
 WDR77
WD repeat domain 77
chr16_+_71392616 0.437 ENST00000349553.5
ENST00000302628.4
ENST00000562305.1
 CALB2


calbindin 2


chr14_-_50999190 0.436 ENST00000557390.1
 MAP4K5
mitogen-activated protein kinase kinase kinase kinase 5
chr1_-_6557156 0.424 ENST00000537245.1
 PLEKHG5
pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chr3_-_182703688 0.406 ENST00000466812.1
ENST00000487822.1
ENST00000460412.1
ENST00000469954.1
 DCUN1D1



DCN1, defective in cullin neddylation 1, domain containing 1



chr2_-_89442621 0.406 ENST00000492167.1
 IGKV3-20
immunoglobulin kappa variable 3-20
chr14_-_94595993 0.379 ENST00000238609.3
 IFI27L2
interferon, alpha-inducible protein 27-like 2
chr10_-_43762329 0.363 ENST00000395810.1
 RASGEF1A
RasGEF domain family, member 1A
chr22_-_37880543 0.359 ENST00000442496.1
 MFNG
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr16_+_77225071 0.348 ENST00000439557.2
ENST00000545553.1
 MON1B

MON1 secretory trafficking family member B

chr1_-_111991908 0.330 ENST00000235090.5
 WDR77
WD repeat domain 77
chr1_-_11865982 0.328 ENST00000418034.1
 MTHFR
methylenetetrahydrofolate reductase (NAD(P)H)
chr5_-_43313574 0.328 ENST00000325110.6
ENST00000433297.2
 HMGCS1

3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)

chr1_-_26232951 0.327 ENST00000426559.2
ENST00000455785.2
 STMN1

stathmin 1

chr1_-_26232522 0.324 ENST00000399728.1
 STMN1
stathmin 1
chr4_+_169842707 0.322 ENST00000503290.1
 PALLD
palladin, cytoskeletal associated protein

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 27 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 1.2 GO:0019858 cytosine metabolic process(GO:0019858)
0.0 1.1 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.2 0.8 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.2 0.8 GO:0033274 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.1 0.8 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0 0.7 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.5 GO:0009642 response to light intensity(GO:0009642)
0.0 0.4 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 0.4 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.4 GO:0045116 protein neddylation(GO:0045116)
0.1 0.3 GO:0019085 early viral transcription(GO:0019085)
0.1 0.3 GO:0009439 cyanate metabolic process(GO:0009439) cyanate catabolic process(GO:0009440)
0.1 0.3 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.0 0.3 GO:0070458 cellular detoxification of nitrogen compound(GO:0070458)
0.0 0.3 GO:0003334 keratinocyte development(GO:0003334)
0.2 0.2 GO:0045994 positive regulation of translational initiation by iron(GO:0045994)
0.1 0.2 GO:0003285 septum secundum development(GO:0003285)
0.1 0.2 GO:0050894 determination of affect(GO:0050894)
0.0 0.2 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.2 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)

Gene overrepresentation in cellular_component category:

Showing 1 to 6 of 6 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.2 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 1.2 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 0.8 GO:0034709 methylosome(GO:0034709)
0.1 0.4 GO:0071749 IgA immunoglobulin complex(GO:0071745) IgA immunoglobulin complex, circulating(GO:0071746) monomeric IgA immunoglobulin complex(GO:0071748) polymeric IgA immunoglobulin complex(GO:0071749) secretory IgA immunoglobulin complex(GO:0071751)
0.0 0.4 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 0.2 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 21 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 1.2 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 1.1 GO:0001786 phosphatidylserine binding(GO:0001786)
0.2 0.8 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.0 0.8 GO:0016273 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.0 0.7 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 0.4 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.4 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.4 GO:0097602 cullin family protein binding(GO:0097602)
0.1 0.3 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.1 0.3 GO:0016784 3-mercaptopyruvate sulfurtransferase activity(GO:0016784)
0.1 0.3 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.3 GO:0043295 glutathione binding(GO:0043295)
0.0 0.3 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 0.2 GO:0031877 somatostatin receptor binding(GO:0031877)
0.0 0.2 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.2 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.1 GO:0015275 stretch-activated, cation-selective, calcium channel activity(GO:0015275)
0.0 0.1 GO:0015226 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.0 0.1 GO:0004803 transposase activity(GO:0004803)
0.0 0.1 GO:0030274 LIM domain binding(GO:0030274)

Gene overrepresentation in C2:CP category:

Showing 1 to 1 of 1 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.8 PID_P38_GAMMA_DELTA_PATHWAY Signaling mediated by p38-gamma and p38-delta

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 5 of 5 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.2 REACTOME_PYRIMIDINE_METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.8 REACTOME_METABOLISM_OF_NON_CODING_RNA Genes involved in Metabolism of non-coding RNA
0.0 0.4 REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.3 REACTOME_CHOLESTEROL_BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.1 REACTOME_REGULATION_OF_GLUCOKINASE_BY_GLUCOKINASE_REGULATORY_PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein