Motif ID: NR1I3

Z-value: 0.363


Transcription factors associated with NR1I3:

Gene SymbolEntrez IDGene Name
NR1I3 ENSG00000143257.7 NR1I3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
NR1I3hg19_v2_chr1_-_161208013_161208092,
hg19_v2_chr1_-_161207953_161207975		-0.311.3e-01Click!


Activity profile for motif NR1I3.

activity profile for motif NR1I3


Sorted Z-values histogram for motif NR1I3

Sorted Z-values for motif NR1I3



Network of associatons between targets according to the STRING database.



First level regulatory network of NR1I3

PNG image of the network

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Top targets:


Showing 1 to 20 of 100 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_+_32407619 1.567 ENST00000395388.2
ENST00000374982.5
 HLA-DRA

major histocompatibility complex, class II, DR alpha

chrX_-_15619076 0.727 ENST00000252519.3
 ACE2
angiotensin I converting enzyme 2
chr9_-_75567962 0.528 ENST00000297785.3
ENST00000376939.1
 ALDH1A1

aldehyde dehydrogenase 1 family, member A1

chr5_+_156712372 0.525 ENST00000541131.1
 CYFIP2
cytoplasmic FMR1 interacting protein 2
chr1_+_26036093 0.476 ENST00000374329.1
 MAN1C1
mannosidase, alpha, class 1C, member 1
chr12_+_53817633 0.456 ENST00000257863.4
ENST00000550311.1
ENST00000379791.3
 AMHR2


anti-Mullerian hormone receptor, type II


chr1_-_20126365 0.423 ENST00000294543.6
ENST00000375122.2
 TMCO4

transmembrane and coiled-coil domains 4

chr12_-_108991812 0.243 ENST00000392806.3
ENST00000547567.1
 TMEM119

transmembrane protein 119

chr1_-_23886285 0.222 ENST00000374561.5
 ID3
inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
chr17_-_34270668 0.217 ENST00000293274.4
 LYZL6
lysozyme-like 6
chr17_-_34270697 0.214 ENST00000585556.1
 LYZL6
lysozyme-like 6
chr6_-_56258892 0.209 ENST00000370819.1
 COL21A1
collagen, type XXI, alpha 1
chr9_+_75766763 0.209 ENST00000456643.1
ENST00000415424.1
 ANXA1

annexin A1

chr6_+_33422343 0.192 ENST00000395064.2
 ZBTB9
zinc finger and BTB domain containing 9
chr11_+_63137251 0.191 ENST00000310969.4
ENST00000279178.3
 SLC22A9

solute carrier family 22 (organic anion transporter), member 9

chrX_+_128872998 0.188 ENST00000371106.3
 XPNPEP2
X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound
chr16_+_30710462 0.178 ENST00000262518.4
ENST00000395059.2
ENST00000344771.4
 SRCAP


Snf2-related CREBBP activator protein


chr7_+_101460882 0.176 ENST00000292535.7
ENST00000549414.2
ENST00000550008.2
ENST00000546411.2
ENST00000556210.1
 CUX1




cut-like homeobox 1




chr1_+_15250596 0.173 ENST00000361144.5
 KAZN
kazrin, periplakin interacting protein
chr17_+_32582293 0.166 ENST00000580907.1
ENST00000225831.4
 CCL2

chemokine (C-C motif) ligand 2


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 22 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 1.6 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.1 0.7 GO:0003051 angiotensin-mediated drinking behavior(GO:0003051)
0.1 0.5 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.1 0.5 GO:1902613 regulation of anti-Mullerian hormone signaling pathway(GO:1902612) negative regulation of anti-Mullerian hormone signaling pathway(GO:1902613) anti-Mullerian hormone signaling pathway(GO:1990262)
0.1 0.5 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.1 0.5 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0 0.4 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 0.3 GO:0044375 regulation of peroxisome size(GO:0044375)
0.1 0.2 GO:0014839 myoblast migration involved in skeletal muscle regeneration(GO:0014839)
0.1 0.2 GO:2000502 negative regulation of natural killer cell chemotaxis(GO:2000502)
0.0 0.2 GO:0009956 radial pattern formation(GO:0009956)
0.0 0.2 GO:0033690 positive regulation of osteoblast proliferation(GO:0033690)
0.0 0.2 GO:0015747 urate transport(GO:0015747)
0.0 0.2 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0 0.1 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.0 0.1 GO:0002155 regulation of thyroid hormone mediated signaling pathway(GO:0002155) kinin cascade(GO:0002254) plasma kallikrein-kinin cascade(GO:0002353)
0.0 0.1 GO:1903906 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.0 0.1 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.0 0.1 GO:1900920 regulation of amino acid uptake involved in synaptic transmission(GO:0051941) regulation of glutamate uptake involved in transmission of nerve impulse(GO:0051946) regulation of L-glutamate import(GO:1900920)
0.0 0.1 GO:0097068 response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386)

Gene overrepresentation in cellular_component category:

Showing 1 to 5 of 5 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.6 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.4 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.3 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.2 GO:0031313 extrinsic component of external side of plasma membrane(GO:0031232) extrinsic component of endosome membrane(GO:0031313)
0.0 0.1 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237) alphav-beta3 integrin-vitronectin complex(GO:0071062)

Gene overrepresentation in molecular_function category:

Showing 1 to 16 of 16 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.6 GO:0032395 MHC class II receptor activity(GO:0032395)
0.1 0.7 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.1 0.5 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.1 0.5 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.0 0.5 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.4 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.2 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.0 0.2 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.2 GO:0035500 MH2 domain binding(GO:0035500)
0.0 0.2 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.1 GO:0008808 cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572) CDP-diacylglycerol-phosphatidylglycerol phosphatidyltransferase activity(GO:0043337)
0.0 0.1 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.0 0.1 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.0 0.1 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.0 0.1 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.1 GO:0004111 creatine kinase activity(GO:0004111)

Gene overrepresentation in C2:CP category:

Showing 1 to 2 of 2 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.6 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4
0.0 0.5 PID_ALK2_PATHWAY ALK2 signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 1 of 1 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.5 REACTOME_ETHANOL_OXIDATION Genes involved in Ethanol oxidation