Motif ID: NR2C1

Z-value: 0.365


Transcription factors associated with NR2C1:

Gene SymbolEntrez IDGene Name
NR2C1 ENSG00000120798.12 NR2C1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
NR2C1hg19_v2_chr12_-_95467267_95467350-0.301.6e-01Click!


Activity profile for motif NR2C1.

activity profile for motif NR2C1


Sorted Z-values histogram for motif NR2C1

Sorted Z-values for motif NR2C1



Network of associatons between targets according to the STRING database.



First level regulatory network of NR2C1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 163 entries
PromoterScoreRefseqGene SymbolGene Name
chrX_+_38420783 0.660 ENST00000422612.2
ENST00000286824.6
ENST00000545599.1
 TSPAN7


tetraspanin 7


chrX_+_38420623 0.303 ENST00000378482.2
 TSPAN7
tetraspanin 7
chr10_+_127661942 0.271 ENST00000417114.1
ENST00000445510.1
ENST00000368691.1
 FANK1


fibronectin type III and ankyrin repeat domains 1


chr14_+_105212297 0.242 ENST00000556623.1
ENST00000555674.1
 ADSSL1

adenylosuccinate synthase like 1

chr14_+_74035763 0.204 ENST00000238651.5
 ACOT2
acyl-CoA thioesterase 2
chr19_-_38806390 0.200 ENST00000589247.1
ENST00000329420.8
ENST00000591784.1
 YIF1B


Yip1 interacting factor homolog B (S. cerevisiae)


chr9_-_34397800 0.197 ENST00000297623.2
 C9orf24
chromosome 9 open reading frame 24
chr14_+_74003818 0.196 ENST00000311148.4
 ACOT1
acyl-CoA thioesterase 1
chr19_+_6464502 0.188 ENST00000308243.7
 CRB3
crumbs homolog 3 (Drosophila)
chr19_-_38806540 0.183 ENST00000592694.1
 YIF1B
Yip1 interacting factor homolog B (S. cerevisiae)
chr15_+_82555125 0.174 ENST00000566205.1
ENST00000339465.5
ENST00000569120.1
ENST00000566861.1
 FAM154B



family with sequence similarity 154, member B



chr19_-_38806560 0.174 ENST00000591755.1
ENST00000337679.8
ENST00000339413.6
 YIF1B


Yip1 interacting factor homolog B (S. cerevisiae)


chr20_+_44486246 0.172 ENST00000255152.2
ENST00000454862.2
 ZSWIM3

zinc finger, SWIM-type containing 3

chr3_-_50605077 0.167 ENST00000426034.1
ENST00000441239.1
 C3orf18

chromosome 3 open reading frame 18

chr3_-_58613323 0.164 ENST00000474531.1
ENST00000465970.1
 FAM107A

family with sequence similarity 107, member A

chr19_-_48867171 0.163 ENST00000377431.2
ENST00000436660.2
ENST00000541566.1
 TMEM143


transmembrane protein 143


chr6_+_33172407 0.162 ENST00000374662.3
 HSD17B8
hydroxysteroid (17-beta) dehydrogenase 8
chr19_-_48867291 0.162 ENST00000435956.3
 TMEM143
transmembrane protein 143
chr13_+_100741269 0.157 ENST00000376286.4
ENST00000376279.3
ENST00000376285.1
 PCCA


propionyl CoA carboxylase, alpha polypeptide


chr8_-_80680078 0.150 ENST00000337919.5
ENST00000354724.3
 HEY1

hes-related family bHLH transcription factor with YRPW motif 1


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 20 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 0.2 GO:0071484 cellular response to light intensity(GO:0071484)
0.0 0.2 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.0 0.2 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.0 0.1 GO:2000820 negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000820)
0.0 0.1 GO:2000097 chronological cell aging(GO:0001300) regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.0 0.1 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0 0.1 GO:0006021 inositol biosynthetic process(GO:0006021)
0.0 0.1 GO:1903570 regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.0 0.1 GO:0006196 AMP catabolic process(GO:0006196)
0.0 0.1 GO:1990034 cellular response to corticosterone stimulus(GO:0071386) calcium ion export from cell(GO:1990034)
0.0 0.1 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0 0.1 GO:0036109 alpha-linolenic acid metabolic process(GO:0036109)
0.0 0.1 GO:0045204 MAPK export from nucleus(GO:0045204)
0.0 0.1 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.0 0.1 GO:0042335 cuticle development(GO:0042335)
0.0 0.0 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.0 0.0 GO:0098937 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
0.0 0.0 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.0 0.0 GO:0035964 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0 0.0 GO:0009786 regulation of asymmetric cell division(GO:0009786)

Gene overrepresentation in cellular_component category:

Showing 1 to 2 of 2 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 0.2 GO:0031379 RNA-directed RNA polymerase complex(GO:0031379)
0.0 0.0 GO:0072534 perineuronal net(GO:0072534)

Gene overrepresentation in molecular_function category:

Showing 1 to 10 of 10 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.5 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.1 0.2 GO:0004019 adenylosuccinate synthase activity(GO:0004019)
0.0 0.2 GO:0070404 NADH binding(GO:0070404)
0.0 0.2 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.1 GO:0035939 microsatellite binding(GO:0035939)
0.0 0.1 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0 0.1 GO:0004075 biotin carboxylase activity(GO:0004075) biotin binding(GO:0009374)
0.0 0.1 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.1 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.0 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 1 of 1 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.2 REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis