Motif ID: NR2F1

Z-value: 0.610


Transcription factors associated with NR2F1:

Gene SymbolEntrez IDGene Name
NR2F1 ENSG00000175745.7 NR2F1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
NR2F1hg19_v2_chr5_+_92919043_92919082-0.193.8e-01Click!


Activity profile for motif NR2F1.

activity profile for motif NR2F1


Sorted Z-values histogram for motif NR2F1

Sorted Z-values for motif NR2F1



Network of associatons between targets according to the STRING database.



First level regulatory network of NR2F1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr20_-_7921090 1.812 ENST00000378789.3
HAO1
hydroxyacid oxidase (glycolate oxidase) 1
chr20_+_31755934 1.045 ENST00000354932.5
BPIFA2
BPI fold containing family A, member 2
chr9_-_39239171 0.961 ENST00000358144.2
CNTNAP3
contactin associated protein-like 3
chr11_+_66624527 0.723 ENST00000393952.3
LRFN4
leucine rich repeat and fibronectin type III domain containing 4
chr16_+_2880157 0.706 ENST00000382280.3
ZG16B
zymogen granule protein 16B
chr10_-_129691195 0.663 ENST00000368671.3
CLRN3
clarin 3
chr11_-_123756334 0.609 ENST00000528595.1
ENST00000375026.2
TMEM225

transmembrane protein 225

chr16_+_2880296 0.598 ENST00000571723.1
ZG16B
zymogen granule protein 16B
chr16_+_2880254 0.585 ENST00000570670.1
ZG16B
zymogen granule protein 16B
chr7_-_75452673 0.546 ENST00000416943.1
CCL24
chemokine (C-C motif) ligand 24
chr16_+_2880369 0.542 ENST00000572863.1
ZG16B
zymogen granule protein 16B
chr7_+_192969 0.525 ENST00000313766.5
FAM20C
family with sequence similarity 20, member C
chr19_+_50919056 0.517 ENST00000599632.1
CTD-2545M3.6
CTD-2545M3.6
chrX_-_108868390 0.501 ENST00000372101.2
KCNE1L
KCNE1-like
chr10_-_54531406 0.499 ENST00000373968.3
MBL2
mannose-binding lectin (protein C) 2, soluble
chr1_+_153940713 0.485 ENST00000368601.1
ENST00000368603.1
ENST00000368600.3
CREB3L4


cAMP responsive element binding protein 3-like 4


chr7_-_229557 0.452 ENST00000514988.1
AC145676.2
Uncharacterized protein
chr2_-_152382500 0.446 ENST00000434685.1
NEB
nebulin
chr1_-_109618566 0.407 ENST00000338366.5
TAF13
TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
chr10_-_17171817 0.401 ENST00000377833.4
CUBN
cubilin (intrinsic factor-cobalamin receptor)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 71 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.4 GO:0001895 retina homeostasis(GO:0001895)
0.2 1.8 GO:0009441 glycolate metabolic process(GO:0009441)
0.0 1.1 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 0.8 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.2 0.7 GO:0070902 mitochondrial tRNA pseudouridine synthesis(GO:0070902)
0.1 0.7 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.7 GO:0072189 ureter development(GO:0072189)
0.2 0.5 GO:0097187 dentinogenesis(GO:0097187)
0.1 0.5 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
0.1 0.5 GO:0019344 cysteine biosynthetic process(GO:0019344)
0.0 0.5 GO:0043968 histone H2A acetylation(GO:0043968)
0.1 0.4 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.1 0.4 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.4 GO:1904338 regulation of dopaminergic neuron differentiation(GO:1904338)
0.0 0.4 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.4 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.4 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.1 0.3 GO:2000583 renal albumin absorption(GO:0097018) regulation of renal albumin absorption(GO:2000532) regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584)
0.1 0.3 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.1 0.3 GO:0015692 lead ion transport(GO:0015692)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 27 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.9 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.6 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.5 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.1 0.4 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.4 GO:0098574 cytoplasmic side of lysosomal membrane(GO:0098574)
0.0 0.4 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.4 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.4 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.1 0.3 GO:0072534 perineuronal net(GO:0072534)
0.1 0.3 GO:0070826 paraferritin complex(GO:0070826)
0.1 0.2 GO:0031251 PAN complex(GO:0031251)
0.0 0.2 GO:0036398 TCR signalosome(GO:0036398)
0.0 0.2 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.2 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.0 0.2 GO:0071953 elastic fiber(GO:0071953)
0.0 0.2 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.2 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.2 GO:0001520 outer dense fiber(GO:0001520)
0.0 0.2 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.1 GO:0033263 CORVET complex(GO:0033263)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 53 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 1.8 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.0 1.0 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.8 GO:0042043 neurexin family protein binding(GO:0042043)
0.2 0.7 GO:0004730 pseudouridylate synthase activity(GO:0004730)
0.0 0.6 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.6 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.1 0.5 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.0 0.5 GO:0005537 mannose binding(GO:0005537)
0.0 0.5 GO:0008392 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.0 0.5 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.5 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.1 0.4 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.0 0.4 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.4 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.4 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.1 0.3 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.1 0.3 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.0 0.3 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.0 0.3 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.3 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)

Gene overrepresentation in C2:CP category:

Showing 1 to 2 of 2 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.2 ST_IL_13_PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.2 PID_FOXM1_PATHWAY FOXM1 transcription factor network

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 11 of 11 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.8 REACTOME_BASIGIN_INTERACTIONS Genes involved in Basigin interactions
0.1 0.7 REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.4 REACTOME_SIGNALING_BY_FGFR3_MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 0.4 REACTOME_HDL_MEDIATED_LIPID_TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.4 REACTOME_DEADENYLATION_OF_MRNA Genes involved in Deadenylation of mRNA
0.0 0.3 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.3 REACTOME_RECYCLING_OF_BILE_ACIDS_AND_SALTS Genes involved in Recycling of bile acids and salts
0.0 0.3 REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.3 REACTOME_GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.2 REACTOME_VITAMIN_B5_PANTOTHENATE_METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.2 REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS Genes involved in Elevation of cytosolic Ca2+ levels