Motif ID: OLIG2_NEUROD1_ATOH1
Z-value: 0.851
Transcription factors associated with OLIG2_NEUROD1_ATOH1:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
ATOH1 | ENSG00000172238.3 | ATOH1 |
NEUROD1 | ENSG00000162992.3 | NEUROD1 |
OLIG2 | ENSG00000205927.4 | OLIG2 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
NEUROD1 | hg19_v2_chr2_-_182545603_182545603 | 0.41 | 4.7e-02 | Click! |
ATOH1 | hg19_v2_chr4_+_94750014_94750042 | -0.17 | 4.2e-01 | Click! |
OLIG2 | hg19_v2_chr21_+_34398153_34398250 | -0.03 | 8.8e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.8 | 3.3 | GO:0033123 | positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123) |
0.5 | 1.6 | GO:0070563 | negative regulation of vitamin D receptor signaling pathway(GO:0070563) |
0.4 | 1.3 | GO:0060279 | regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279) |
0.4 | 1.2 | GO:0046521 | sphingoid catabolic process(GO:0046521) |
0.4 | 1.4 | GO:0036378 | calcitriol biosynthetic process from calciol(GO:0036378) |
0.3 | 1.0 | GO:0007206 | phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206) |
0.3 | 0.9 | GO:0019072 | viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074) |
0.3 | 2.3 | GO:0003065 | positive regulation of heart rate by epinephrine(GO:0003065) |
0.2 | 0.7 | GO:0061073 | ciliary body morphogenesis(GO:0061073) |
0.2 | 1.2 | GO:0018101 | protein citrullination(GO:0018101) histone citrullination(GO:0036414) |
0.2 | 1.1 | GO:0072717 | cellular response to actinomycin D(GO:0072717) |
0.2 | 1.9 | GO:0002329 | pre-B cell differentiation(GO:0002329) |
0.2 | 2.2 | GO:0015712 | hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760) |
0.2 | 4.3 | GO:0016540 | protein autoprocessing(GO:0016540) |
0.2 | 0.6 | GO:1901301 | regulation of cargo loading into COPII-coated vesicle(GO:1901301) |
0.2 | 1.7 | GO:0038028 | insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028) |
0.2 | 0.8 | GO:0090038 | negative regulation of protein kinase C signaling(GO:0090038) |
0.2 | 0.9 | GO:0018125 | peptidyl-cysteine methylation(GO:0018125) |
0.2 | 2.0 | GO:0046886 | positive regulation of hormone biosynthetic process(GO:0046886) |
0.2 | 0.6 | GO:0010982 | regulation of high-density lipoprotein particle clearance(GO:0010982) |
0.2 | 0.8 | GO:0007525 | somatic muscle development(GO:0007525) |
0.1 | 0.7 | GO:0021633 | optic nerve structural organization(GO:0021633) |
0.1 | 0.5 | GO:0043456 | regulation of pentose-phosphate shunt(GO:0043456) |
0.1 | 0.5 | GO:0014846 | esophagus smooth muscle contraction(GO:0014846) |
0.1 | 0.4 | GO:0055073 | cadmium ion homeostasis(GO:0055073) lysosomal membrane organization(GO:0097212) negative regulation of hydrogen peroxide catabolic process(GO:2000296) regulation of oxygen metabolic process(GO:2000374) |
0.1 | 0.6 | GO:0014835 | myoblast differentiation involved in skeletal muscle regeneration(GO:0014835) |
0.1 | 0.7 | GO:0014043 | negative regulation of neuron maturation(GO:0014043) |
0.1 | 0.4 | GO:0097325 | melanocyte proliferation(GO:0097325) |
0.1 | 0.4 | GO:1904647 | response to rotenone(GO:1904647) |
0.1 | 0.8 | GO:2000189 | positive regulation of cholesterol homeostasis(GO:2000189) |
0.1 | 0.5 | GO:0044240 | multicellular organism lipid catabolic process(GO:0044240) |
0.1 | 0.4 | GO:0039534 | negative regulation of MDA-5 signaling pathway(GO:0039534) |
0.1 | 0.3 | GO:2000705 | dense core granule biogenesis(GO:0061110) positive regulation of relaxation of cardiac muscle(GO:1901899) regulation of dense core granule biogenesis(GO:2000705) |
0.1 | 0.6 | GO:0002326 | B cell lineage commitment(GO:0002326) |
0.1 | 0.5 | GO:0097498 | endothelial tube lumen extension(GO:0097498) |
0.1 | 1.4 | GO:0051256 | mitotic spindle midzone assembly(GO:0051256) |
0.1 | 0.5 | GO:0006287 | base-excision repair, gap-filling(GO:0006287) |
0.1 | 0.2 | GO:1903862 | positive regulation of oxidative phosphorylation(GO:1903862) |
0.1 | 0.3 | GO:0036269 | swimming behavior(GO:0036269) |
0.1 | 0.9 | GO:0007144 | female meiosis I(GO:0007144) |
0.1 | 0.3 | GO:0044752 | response to human chorionic gonadotropin(GO:0044752) |
0.1 | 0.7 | GO:0048050 | post-embryonic eye morphogenesis(GO:0048050) |
0.1 | 0.4 | GO:0000738 | DNA catabolic process, exonucleolytic(GO:0000738) |
0.1 | 0.3 | GO:0030311 | poly-N-acetyllactosamine biosynthetic process(GO:0030311) |
0.1 | 0.2 | GO:0040010 | positive regulation of growth rate(GO:0040010) regulation of gastric mucosal blood circulation(GO:1904344) positive regulation of gastric mucosal blood circulation(GO:1904346) gastric mucosal blood circulation(GO:1990768) |
0.1 | 0.2 | GO:0021938 | ventral midline development(GO:0007418) smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation(GO:0021938) |
0.1 | 0.6 | GO:0017185 | peptidyl-lysine hydroxylation(GO:0017185) |
0.1 | 0.3 | GO:0007538 | primary sex determination(GO:0007538) |
0.1 | 0.8 | GO:0030202 | heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210) |
0.1 | 0.2 | GO:0098968 | cochlear nucleus development(GO:0021747) neurotransmitter receptor transport postsynaptic membrane to endosome(GO:0098968) |
0.1 | 0.4 | GO:0015811 | L-alanine transport(GO:0015808) L-cystine transport(GO:0015811) |
0.1 | 0.2 | GO:0021569 | rhombomere 3 development(GO:0021569) |
0.1 | 0.3 | GO:0046340 | diacylglycerol catabolic process(GO:0046340) |
0.1 | 0.2 | GO:2000612 | pronephric field specification(GO:0039003) pattern specification involved in pronephros development(GO:0039017) thyroid-stimulating hormone secretion(GO:0070460) kidney field specification(GO:0072004) regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis(GO:0072304) negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis(GO:0072305) mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis(GO:0072309) mesenchymal cell apoptotic process involved in metanephros development(GO:1900200) apoptotic process involved in metanephric collecting duct development(GO:1900204) apoptotic process involved in metanephric nephron tubule development(GO:1900205) regulation of mesenchymal cell apoptotic process involved in metanephros development(GO:1900211) negative regulation of mesenchymal cell apoptotic process involved in metanephros development(GO:1900212) regulation of apoptotic process involved in metanephric collecting duct development(GO:1900214) negative regulation of apoptotic process involved in metanephric collecting duct development(GO:1900215) regulation of apoptotic process involved in metanephric nephron tubule development(GO:1900217) negative regulation of apoptotic process involved in metanephric nephron tubule development(GO:1900218) mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis(GO:1901147) regulation of metanephric DCT cell differentiation(GO:2000592) positive regulation of metanephric DCT cell differentiation(GO:2000594) regulation of thyroid-stimulating hormone secretion(GO:2000612) |
0.1 | 0.3 | GO:0071477 | hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477) |
0.1 | 1.9 | GO:0095500 | acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145) |
0.1 | 0.5 | GO:0010724 | regulation of definitive erythrocyte differentiation(GO:0010724) |
0.1 | 0.2 | GO:1902630 | regulation of membrane hyperpolarization(GO:1902630) |
0.1 | 1.3 | GO:0071481 | cellular response to X-ray(GO:0071481) |
0.1 | 0.4 | GO:0021564 | vagus nerve development(GO:0021564) |
0.1 | 0.3 | GO:1903377 | negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377) |
0.1 | 0.3 | GO:0061056 | sclerotome development(GO:0061056) |
0.1 | 0.7 | GO:0050966 | detection of mechanical stimulus involved in sensory perception of pain(GO:0050966) |
0.1 | 0.7 | GO:1905049 | negative regulation of metallopeptidase activity(GO:1905049) |
0.0 | 0.1 | GO:0038043 | interleukin-5-mediated signaling pathway(GO:0038043) |
0.0 | 1.0 | GO:0035090 | maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199) |
0.0 | 0.2 | GO:1905098 | negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098) |
0.0 | 0.3 | GO:0098528 | skeletal muscle fiber differentiation(GO:0098528) |
0.0 | 0.2 | GO:0060729 | intestinal epithelial structure maintenance(GO:0060729) |
0.0 | 0.6 | GO:0010991 | regulation of SMAD protein complex assembly(GO:0010990) negative regulation of SMAD protein complex assembly(GO:0010991) |
0.0 | 0.1 | GO:2000297 | negative regulation of synapse maturation(GO:2000297) |
0.0 | 0.3 | GO:1905245 | regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902959) positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) regulation of aspartic-type peptidase activity(GO:1905245) positive regulation of aspartic-type peptidase activity(GO:1905247) |
0.0 | 3.2 | GO:0043268 | positive regulation of potassium ion transport(GO:0043268) |
0.0 | 0.2 | GO:0048496 | maintenance of organ identity(GO:0048496) |
0.0 | 0.3 | GO:0009730 | detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594) |
0.0 | 0.3 | GO:2000782 | regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) positive regulation of barbed-end actin filament capping(GO:2000814) |
0.0 | 0.1 | GO:0060809 | mesodermal to mesenchymal transition involved in gastrulation(GO:0060809) |
0.0 | 0.0 | GO:1904347 | regulation of small intestine smooth muscle contraction(GO:1904347) positive regulation of small intestine smooth muscle contraction(GO:1904349) small intestine smooth muscle contraction(GO:1990770) |
0.0 | 0.3 | GO:0036089 | cleavage furrow formation(GO:0036089) |
0.0 | 0.1 | GO:0033198 | response to ATP(GO:0033198) |
0.0 | 0.2 | GO:0072086 | specification of loop of Henle identity(GO:0072086) pattern specification involved in metanephros development(GO:0072268) |
0.0 | 0.9 | GO:0035855 | megakaryocyte development(GO:0035855) |
0.0 | 0.3 | GO:0098903 | regulation of membrane repolarization during action potential(GO:0098903) |
0.0 | 0.2 | GO:0014816 | skeletal muscle satellite cell differentiation(GO:0014816) |
0.0 | 0.2 | GO:1902723 | negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723) |
0.0 | 0.2 | GO:0038018 | Wnt receptor catabolic process(GO:0038018) |
0.0 | 0.0 | GO:0071335 | submandibular salivary gland formation(GO:0060661) hair follicle cell proliferation(GO:0071335) regulation of hair follicle cell proliferation(GO:0071336) positive regulation of hair follicle cell proliferation(GO:0071338) |
0.0 | 0.2 | GO:0010609 | mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) |
0.0 | 1.1 | GO:0042753 | positive regulation of circadian rhythm(GO:0042753) |
0.0 | 0.8 | GO:0007175 | negative regulation of epidermal growth factor-activated receptor activity(GO:0007175) |
0.0 | 0.8 | GO:0007216 | G-protein coupled glutamate receptor signaling pathway(GO:0007216) |
0.0 | 0.2 | GO:0003335 | corneocyte development(GO:0003335) |
0.0 | 0.1 | GO:0014878 | response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878) |
0.0 | 0.2 | GO:1904879 | positive regulation of high voltage-gated calcium channel activity(GO:1901843) positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879) |
0.0 | 0.9 | GO:0050908 | detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962) |
0.0 | 0.1 | GO:1903215 | negative regulation of protein targeting to mitochondrion(GO:1903215) |
0.0 | 0.3 | GO:1990564 | protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592) |
0.0 | 0.3 | GO:0007221 | positive regulation of transcription of Notch receptor target(GO:0007221) |
0.0 | 0.5 | GO:0001867 | complement activation, lectin pathway(GO:0001867) |
0.0 | 0.3 | GO:0006741 | NADP biosynthetic process(GO:0006741) |
0.0 | 0.1 | GO:0007406 | negative regulation of neuroblast proliferation(GO:0007406) |
0.0 | 0.3 | GO:0034351 | regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351) |
0.0 | 1.2 | GO:0043567 | regulation of insulin-like growth factor receptor signaling pathway(GO:0043567) |
0.0 | 0.5 | GO:0015693 | magnesium ion transport(GO:0015693) |
0.0 | 0.4 | GO:0002315 | marginal zone B cell differentiation(GO:0002315) |
0.0 | 0.1 | GO:0044179 | hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331) |
0.0 | 0.1 | GO:0050902 | leukocyte adhesive activation(GO:0050902) |
0.0 | 0.1 | GO:0007402 | ganglion mother cell fate determination(GO:0007402) |
0.0 | 0.1 | GO:1903347 | negative regulation of bicellular tight junction assembly(GO:1903347) |
0.0 | 0.1 | GO:0007499 | ectoderm and mesoderm interaction(GO:0007499) |
0.0 | 0.1 | GO:0002337 | B-1a B cell differentiation(GO:0002337) |
0.0 | 0.4 | GO:2001224 | positive regulation of neuron migration(GO:2001224) |
0.0 | 0.1 | GO:0072275 | metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277) |
0.0 | 0.1 | GO:0046167 | glycerol-3-phosphate biosynthetic process(GO:0046167) |
0.0 | 0.2 | GO:0021942 | radial glia guided migration of Purkinje cell(GO:0021942) |
0.0 | 0.2 | GO:0051725 | protein de-ADP-ribosylation(GO:0051725) |
0.0 | 0.1 | GO:0015917 | aminophospholipid transport(GO:0015917) |
0.0 | 0.2 | GO:2000048 | negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048) |
0.0 | 0.5 | GO:0046069 | cGMP catabolic process(GO:0046069) |
0.0 | 0.1 | GO:2000639 | regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639) |
0.0 | 1.5 | GO:0097435 | fibril organization(GO:0097435) |
0.0 | 0.3 | GO:0048262 | determination of dorsal/ventral asymmetry(GO:0048262) |
0.0 | 0.2 | GO:0035803 | egg coat formation(GO:0035803) |
0.0 | 0.1 | GO:0071313 | cellular response to caffeine(GO:0071313) |
0.0 | 0.1 | GO:0044501 | modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032) |
0.0 | 0.1 | GO:1901842 | negative regulation of high voltage-gated calcium channel activity(GO:1901842) |
0.0 | 0.3 | GO:0046598 | positive regulation of viral entry into host cell(GO:0046598) |
0.0 | 0.9 | GO:0007271 | synaptic transmission, cholinergic(GO:0007271) |
0.0 | 0.2 | GO:0032876 | negative regulation of DNA endoreduplication(GO:0032876) |
0.0 | 0.3 | GO:0034983 | peptidyl-lysine deacetylation(GO:0034983) |
0.0 | 0.1 | GO:0043686 | co-translational protein modification(GO:0043686) |
0.0 | 0.6 | GO:0060712 | spongiotrophoblast layer development(GO:0060712) |
0.0 | 0.2 | GO:0001886 | endothelial cell morphogenesis(GO:0001886) |
0.0 | 0.1 | GO:0006311 | meiotic gene conversion(GO:0006311) male meiosis chromosome segregation(GO:0007060) gene conversion(GO:0035822) |
0.0 | 0.1 | GO:0035105 | sterol regulatory element binding protein import into nucleus(GO:0035105) |
0.0 | 0.6 | GO:2000311 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311) |
0.0 | 0.1 | GO:0099640 | axo-dendritic protein transport(GO:0099640) |
0.0 | 1.5 | GO:0000186 | activation of MAPKK activity(GO:0000186) |
0.0 | 0.2 | GO:1904627 | response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628) |
0.0 | 0.4 | GO:0042136 | neurotransmitter biosynthetic process(GO:0042136) |
0.0 | 4.3 | GO:0031424 | keratinization(GO:0031424) |
0.0 | 0.2 | GO:0003344 | pericardium morphogenesis(GO:0003344) |
0.0 | 0.6 | GO:0031581 | hemidesmosome assembly(GO:0031581) |
0.0 | 0.4 | GO:0006198 | cAMP catabolic process(GO:0006198) |
0.0 | 0.0 | GO:0016080 | synaptic vesicle targeting(GO:0016080) |
0.0 | 0.1 | GO:0033292 | T-tubule organization(GO:0033292) |
0.0 | 0.2 | GO:0000012 | single strand break repair(GO:0000012) |
0.0 | 0.5 | GO:0002076 | osteoblast development(GO:0002076) |
0.0 | 0.1 | GO:0019230 | proprioception(GO:0019230) |
0.0 | 0.1 | GO:0042560 | folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560) |
0.0 | 0.7 | GO:0070306 | lens fiber cell differentiation(GO:0070306) |
0.0 | 0.3 | GO:0097094 | craniofacial suture morphogenesis(GO:0097094) |
0.0 | 0.2 | GO:0006682 | galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375) |
0.0 | 0.2 | GO:0010839 | negative regulation of keratinocyte proliferation(GO:0010839) |
0.0 | 0.2 | GO:0018230 | peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231) |
0.0 | 2.5 | GO:0043149 | contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149) |
0.0 | 0.1 | GO:0021586 | olfactory learning(GO:0008355) pons maturation(GO:0021586) cellular alkene metabolic process(GO:0043449) |
0.0 | 0.1 | GO:0001807 | type IV hypersensitivity(GO:0001806) regulation of type IV hypersensitivity(GO:0001807) negative regulation of type IV hypersensitivity(GO:0001808) |
0.0 | 0.0 | GO:1900262 | regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264) |
0.0 | 1.0 | GO:0060395 | SMAD protein signal transduction(GO:0060395) |
0.0 | 0.1 | GO:0006013 | mannose metabolic process(GO:0006013) |
0.0 | 0.1 | GO:0021966 | corticospinal neuron axon guidance(GO:0021966) |
0.0 | 0.1 | GO:1901503 | ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503) |
0.0 | 0.3 | GO:1990118 | sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118) |
0.0 | 0.1 | GO:0006617 | SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617) |
0.0 | 0.1 | GO:0045875 | negative regulation of sister chromatid cohesion(GO:0045875) protein auto-ADP-ribosylation(GO:0070213) |
0.0 | 0.3 | GO:0050930 | induction of positive chemotaxis(GO:0050930) |
0.0 | 0.2 | GO:0060033 | anatomical structure regression(GO:0060033) |
0.0 | 0.2 | GO:0070973 | protein localization to endoplasmic reticulum exit site(GO:0070973) |
0.0 | 0.1 | GO:0048539 | bone marrow development(GO:0048539) |
0.0 | 1.1 | GO:0035690 | cellular response to drug(GO:0035690) |
0.0 | 0.2 | GO:0019509 | L-methionine biosynthetic process from methylthioadenosine(GO:0019509) |
0.0 | 0.1 | GO:0070294 | renal sodium ion absorption(GO:0070294) |
0.0 | 0.3 | GO:0006995 | cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562) |
0.0 | 0.0 | GO:0016185 | synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185) |
0.0 | 0.3 | GO:0014002 | astrocyte development(GO:0014002) |
0.0 | 0.1 | GO:0048133 | germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728) |
0.0 | 0.2 | GO:0030220 | platelet formation(GO:0030220) |
0.0 | 0.0 | GO:0050960 | detection of temperature stimulus involved in thermoception(GO:0050960) detection of chemical stimulus involved in sensory perception of pain(GO:0050968) response to capsazepine(GO:1901594) |
0.0 | 1.6 | GO:0006939 | smooth muscle contraction(GO:0006939) |
0.0 | 0.5 | GO:0002026 | regulation of the force of heart contraction(GO:0002026) |
0.0 | 1.4 | GO:0050911 | detection of chemical stimulus involved in sensory perception of smell(GO:0050911) |
0.0 | 0.1 | GO:2000601 | positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601) |
0.0 | 0.1 | GO:0034334 | adherens junction maintenance(GO:0034334) |
0.0 | 0.1 | GO:0048341 | paraxial mesoderm morphogenesis(GO:0048340) paraxial mesoderm formation(GO:0048341) |
0.0 | 1.8 | GO:1902600 | hydrogen ion transmembrane transport(GO:1902600) |
0.0 | 0.3 | GO:0033622 | integrin activation(GO:0033622) |
0.0 | 0.3 | GO:0043011 | myeloid dendritic cell differentiation(GO:0043011) |
0.0 | 0.2 | GO:0035414 | negative regulation of catenin import into nucleus(GO:0035414) |
0.0 | 0.9 | GO:0051017 | actin filament bundle assembly(GO:0051017) actin filament bundle organization(GO:0061572) |
0.0 | 0.0 | GO:0060437 | lung growth(GO:0060437) |
0.0 | 0.3 | GO:0044030 | regulation of DNA methylation(GO:0044030) |
0.0 | 1.0 | GO:0050829 | defense response to Gram-negative bacterium(GO:0050829) |
0.0 | 0.1 | GO:0060314 | regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314) |
0.0 | 1.7 | GO:0008277 | regulation of G-protein coupled receptor protein signaling pathway(GO:0008277) |
0.0 | 0.1 | GO:0051694 | pointed-end actin filament capping(GO:0051694) |
0.0 | 0.0 | GO:0036496 | regulation of translational initiation by eIF2 alpha dephosphorylation(GO:0036496) |
0.0 | 0.3 | GO:0048268 | clathrin coat assembly(GO:0048268) |
0.0 | 0.7 | GO:0046847 | filopodium assembly(GO:0046847) |
0.0 | 0.4 | GO:0010765 | positive regulation of sodium ion transport(GO:0010765) |
0.0 | 0.1 | GO:0031119 | tRNA pseudouridine synthesis(GO:0031119) |
0.0 | 0.1 | GO:1904893 | negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893) |
0.0 | 0.3 | GO:0045599 | negative regulation of fat cell differentiation(GO:0045599) |
0.0 | 0.0 | GO:1904717 | excitatory chemical synaptic transmission(GO:0098976) regulation of AMPA glutamate receptor clustering(GO:1904717) positive regulation of AMPA glutamate receptor clustering(GO:1904719) |
0.0 | 0.5 | GO:0019933 | cAMP-mediated signaling(GO:0019933) |
0.0 | 0.1 | GO:0046007 | negative regulation of activated T cell proliferation(GO:0046007) |
0.0 | 0.1 | GO:0016240 | autophagosome docking(GO:0016240) |
0.0 | 0.2 | GO:0006853 | carnitine shuttle(GO:0006853) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.4 | 1.3 | GO:0043511 | inhibin complex(GO:0043511) inhibin A complex(GO:0043512) |
0.2 | 1.3 | GO:0097129 | cyclin D2-CDK4 complex(GO:0097129) |
0.2 | 3.7 | GO:0005862 | muscle thin filament tropomyosin(GO:0005862) |
0.1 | 0.6 | GO:0032937 | SREBP-SCAP-Insig complex(GO:0032937) |
0.1 | 0.4 | GO:0097450 | astrocyte end-foot(GO:0097450) |
0.1 | 1.2 | GO:0036454 | insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) |
0.1 | 1.7 | GO:0005751 | mitochondrial respiratory chain complex IV(GO:0005751) |
0.1 | 0.2 | GO:0002139 | stereocilia coupling link(GO:0002139) |
0.0 | 0.6 | GO:1990454 | L-type voltage-gated calcium channel complex(GO:1990454) |
0.0 | 0.1 | GO:1990032 | parallel fiber(GO:1990032) |
0.0 | 4.0 | GO:0045095 | keratin filament(GO:0045095) |
0.0 | 1.0 | GO:0042588 | zymogen granule(GO:0042588) |
0.0 | 0.7 | GO:0033010 | paranodal junction(GO:0033010) |
0.0 | 0.2 | GO:0034750 | Scrib-APC-beta-catenin complex(GO:0034750) |
0.0 | 0.4 | GO:0071438 | invadopodium membrane(GO:0071438) |
0.0 | 0.8 | GO:0032433 | filopodium tip(GO:0032433) |
0.0 | 1.6 | GO:0015629 | actin cytoskeleton(GO:0015629) |
0.0 | 0.2 | GO:0070381 | endosome to plasma membrane transport vesicle(GO:0070381) |
0.0 | 4.5 | GO:0030864 | cortical actin cytoskeleton(GO:0030864) |
0.0 | 2.8 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
0.0 | 0.4 | GO:0030688 | preribosome, small subunit precursor(GO:0030688) |
0.0 | 0.2 | GO:0031262 | Ndc80 complex(GO:0031262) |
0.0 | 1.2 | GO:0030673 | axolemma(GO:0030673) |
0.0 | 2.1 | GO:1904115 | axon cytoplasm(GO:1904115) |
0.0 | 0.3 | GO:0097449 | astrocyte projection(GO:0097449) |
0.0 | 0.6 | GO:0030056 | hemidesmosome(GO:0030056) |
0.0 | 0.8 | GO:0005892 | acetylcholine-gated channel complex(GO:0005892) |
0.0 | 0.2 | GO:0005658 | alpha DNA polymerase:primase complex(GO:0005658) |
0.0 | 0.5 | GO:0001518 | voltage-gated sodium channel complex(GO:0001518) |
0.0 | 0.7 | GO:0043205 | microfibril(GO:0001527) fibril(GO:0043205) |
0.0 | 0.1 | GO:0042788 | polysomal ribosome(GO:0042788) |
0.0 | 0.2 | GO:0016035 | zeta DNA polymerase complex(GO:0016035) |
0.0 | 0.5 | GO:0031618 | nuclear pericentric heterochromatin(GO:0031618) |
0.0 | 0.3 | GO:0042382 | paraspeckles(GO:0042382) |
0.0 | 1.3 | GO:0031941 | filamentous actin(GO:0031941) |
0.0 | 0.5 | GO:0031089 | platelet dense granule lumen(GO:0031089) |
0.0 | 0.3 | GO:0042583 | chromaffin granule(GO:0042583) |
0.0 | 3.0 | GO:0031093 | platelet alpha granule lumen(GO:0031093) |
0.0 | 0.1 | GO:0020018 | ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018) |
0.0 | 0.2 | GO:0070436 | Grb2-EGFR complex(GO:0070436) |
0.0 | 0.3 | GO:0030126 | COPI vesicle coat(GO:0030126) |
0.0 | 0.6 | GO:0016010 | dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665) |
0.0 | 2.4 | GO:0005913 | cell-cell adherens junction(GO:0005913) |
0.0 | 0.4 | GO:0005652 | nuclear lamina(GO:0005652) |
0.0 | 0.1 | GO:0033165 | interphotoreceptor matrix(GO:0033165) |
0.0 | 0.1 | GO:0035976 | AP1 complex(GO:0035976) |
0.0 | 0.2 | GO:0043296 | apical junction complex(GO:0043296) |
0.0 | 0.1 | GO:0043083 | synaptic cleft(GO:0043083) |
0.0 | 0.3 | GO:0045180 | basal cortex(GO:0045180) |
0.0 | 0.2 | GO:0097440 | apical dendrite(GO:0097440) |
0.0 | 0.2 | GO:0030057 | desmosome(GO:0030057) |
0.0 | 1.0 | GO:0031672 | A band(GO:0031672) |
0.0 | 2.8 | GO:0090575 | RNA polymerase II transcription factor complex(GO:0090575) |
0.0 | 0.1 | GO:0000801 | central element(GO:0000801) |
0.0 | 0.1 | GO:0032059 | bleb(GO:0032059) |
0.0 | 2.8 | GO:0055037 | recycling endosome(GO:0055037) |
0.0 | 0.1 | GO:0035748 | myelin sheath abaxonal region(GO:0035748) |
0.0 | 1.8 | GO:0016605 | PML body(GO:0016605) |
0.0 | 0.2 | GO:0002178 | palmitoyltransferase complex(GO:0002178) |
0.0 | 0.1 | GO:0005577 | fibrinogen complex(GO:0005577) |
0.0 | 1.3 | GO:0005604 | basement membrane(GO:0005604) |
0.0 | 1.1 | GO:0034707 | chloride channel complex(GO:0034707) |
0.0 | 0.1 | GO:0097342 | ripoptosome(GO:0097342) |
0.0 | 2.1 | GO:0031227 | intrinsic component of endoplasmic reticulum membrane(GO:0031227) |
0.0 | 0.2 | GO:0000813 | ESCRT I complex(GO:0000813) |
0.0 | 1.1 | GO:0042734 | presynaptic membrane(GO:0042734) |
0.0 | 0.2 | GO:0031254 | uropod(GO:0001931) cell trailing edge(GO:0031254) |
0.0 | 0.1 | GO:0031466 | Cul5-RING ubiquitin ligase complex(GO:0031466) |
0.0 | 0.1 | GO:0000275 | mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) |
0.0 | 0.1 | GO:0070545 | PeBoW complex(GO:0070545) |
0.0 | 0.1 | GO:0001740 | Barr body(GO:0001740) |
0.0 | 0.2 | GO:0034518 | mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518) |
0.0 | 0.5 | GO:0030173 | integral component of Golgi membrane(GO:0030173) |
0.0 | 0.1 | GO:0016461 | unconventional myosin complex(GO:0016461) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.5 | 2.0 | GO:0004874 | aryl hydrocarbon receptor activity(GO:0004874) |
0.4 | 1.3 | GO:0070699 | type II activin receptor binding(GO:0070699) |
0.4 | 1.4 | GO:0070643 | vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643) |
0.3 | 2.2 | GO:0015526 | hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513) |
0.3 | 1.1 | GO:0070180 | large ribosomal subunit rRNA binding(GO:0070180) |
0.3 | 3.3 | GO:0017034 | Rap guanyl-nucleotide exchange factor activity(GO:0017034) |
0.2 | 1.2 | GO:0004668 | protein-arginine deiminase activity(GO:0004668) |
0.2 | 1.2 | GO:0042015 | interleukin-20 binding(GO:0042015) |
0.2 | 0.6 | GO:0030550 | acetylcholine receptor inhibitor activity(GO:0030550) |
0.2 | 1.2 | GO:0017050 | sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050) |
0.2 | 0.5 | GO:0004157 | dihydropyrimidinase activity(GO:0004157) |
0.1 | 0.8 | GO:0015016 | [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016) |
0.1 | 0.5 | GO:0046538 | bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538) |
0.1 | 0.6 | GO:0070644 | vitamin D response element binding(GO:0070644) |
0.1 | 0.4 | GO:0008859 | exoribonuclease II activity(GO:0008859) |
0.1 | 1.0 | GO:0099583 | neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583) |
0.1 | 0.5 | GO:0032038 | myosin II heavy chain binding(GO:0032038) |
0.1 | 0.5 | GO:0033829 | O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829) |
0.1 | 0.6 | GO:0070815 | peptidyl-lysine 5-dioxygenase activity(GO:0070815) |
0.1 | 0.3 | GO:0008192 | RNA guanylyltransferase activity(GO:0008192) |
0.1 | 1.2 | GO:0031995 | insulin-like growth factor II binding(GO:0031995) |
0.1 | 0.3 | GO:0033878 | hormone-sensitive lipase activity(GO:0033878) |
0.1 | 0.4 | GO:0004102 | choline O-acetyltransferase activity(GO:0004102) |
0.1 | 1.8 | GO:0005225 | volume-sensitive anion channel activity(GO:0005225) |
0.1 | 0.9 | GO:0004075 | biotin carboxylase activity(GO:0004075) biotin binding(GO:0009374) |
0.1 | 0.8 | GO:0060002 | plus-end directed microfilament motor activity(GO:0060002) |
0.1 | 1.3 | GO:0030280 | structural constituent of epidermis(GO:0030280) |
0.1 | 0.5 | GO:0008449 | N-acetylglucosamine-6-sulfatase activity(GO:0008449) |
0.1 | 0.5 | GO:0004771 | sterol esterase activity(GO:0004771) |
0.1 | 0.6 | GO:0004465 | lipoprotein lipase activity(GO:0004465) |
0.1 | 0.3 | GO:0016262 | protein N-acetylglucosaminyltransferase activity(GO:0016262) |
0.1 | 0.2 | GO:0031768 | ghrelin receptor binding(GO:0031768) |
0.1 | 0.2 | GO:0001076 | transcription factor activity, RNA polymerase II transcription factor binding(GO:0001076) |
0.1 | 0.4 | GO:0004090 | carbonyl reductase (NADPH) activity(GO:0004090) |
0.1 | 0.5 | GO:0048101 | calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101) |
0.1 | 0.3 | GO:0004991 | parathyroid hormone receptor activity(GO:0004991) |
0.1 | 0.4 | GO:0015180 | L-alanine transmembrane transporter activity(GO:0015180) L-cystine transmembrane transporter activity(GO:0015184) alanine transmembrane transporter activity(GO:0022858) |
0.1 | 1.0 | GO:0035256 | G-protein coupled glutamate receptor binding(GO:0035256) |
0.1 | 7.0 | GO:0008307 | structural constituent of muscle(GO:0008307) |
0.1 | 0.8 | GO:0019957 | C-C chemokine binding(GO:0019957) |
0.1 | 0.2 | GO:0047275 | glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275) |
0.1 | 0.6 | GO:0051525 | NFAT protein binding(GO:0051525) |
0.1 | 0.3 | GO:0004699 | calcium-independent protein kinase C activity(GO:0004699) |
0.1 | 0.2 | GO:0070259 | tyrosyl-DNA phosphodiesterase activity(GO:0070259) |
0.1 | 1.1 | GO:0008093 | cytoskeletal adaptor activity(GO:0008093) |
0.1 | 1.7 | GO:0016676 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
0.0 | 0.1 | GO:0004914 | interleukin-5 receptor activity(GO:0004914) |
0.0 | 0.5 | GO:0051575 | 5'-deoxyribose-5-phosphate lyase activity(GO:0051575) |
0.0 | 0.3 | GO:0035662 | Toll-like receptor 4 binding(GO:0035662) |
0.0 | 0.2 | GO:0031708 | endothelin B receptor binding(GO:0031708) |
0.0 | 1.5 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
0.0 | 0.1 | GO:0098770 | FBXO family protein binding(GO:0098770) |
0.0 | 1.3 | GO:0001965 | G-protein alpha-subunit binding(GO:0001965) |
0.0 | 0.4 | GO:0004704 | NF-kappaB-inducing kinase activity(GO:0004704) |
0.0 | 0.4 | GO:0004115 | 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115) |
0.0 | 1.7 | GO:0043539 | protein serine/threonine kinase activator activity(GO:0043539) |
0.0 | 0.2 | GO:0005166 | neurotrophin p75 receptor binding(GO:0005166) |
0.0 | 1.1 | GO:0031489 | myosin V binding(GO:0031489) |
0.0 | 0.3 | GO:0032051 | clathrin light chain binding(GO:0032051) |
0.0 | 0.5 | GO:0046870 | cadmium ion binding(GO:0046870) |
0.0 | 0.7 | GO:0015271 | outward rectifier potassium channel activity(GO:0015271) |
0.0 | 0.8 | GO:0022848 | acetylcholine-gated cation channel activity(GO:0022848) |
0.0 | 1.3 | GO:0008574 | ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) |
0.0 | 0.9 | GO:0005229 | intracellular calcium activated chloride channel activity(GO:0005229) |
0.0 | 0.3 | GO:0005005 | transmembrane-ephrin receptor activity(GO:0005005) |
0.0 | 2.1 | GO:0004864 | protein phosphatase inhibitor activity(GO:0004864) |
0.0 | 0.1 | GO:0005017 | platelet-derived growth factor-activated receptor activity(GO:0005017) |
0.0 | 0.1 | GO:0004370 | glycerol kinase activity(GO:0004370) |
0.0 | 0.1 | GO:0005173 | stem cell factor receptor binding(GO:0005173) |
0.0 | 0.6 | GO:0008349 | MAP kinase kinase kinase kinase activity(GO:0008349) |
0.0 | 0.2 | GO:0086056 | voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056) |
0.0 | 0.4 | GO:0089720 | caspase binding(GO:0089720) |
0.0 | 0.3 | GO:0015379 | potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820) |
0.0 | 1.1 | GO:0017091 | AU-rich element binding(GO:0017091) |
0.0 | 0.1 | GO:0045518 | interleukin-22 receptor binding(GO:0045518) |
0.0 | 0.3 | GO:0008607 | phosphorylase kinase regulator activity(GO:0008607) |
0.0 | 1.8 | GO:0001102 | RNA polymerase II activating transcription factor binding(GO:0001102) |
0.0 | 0.1 | GO:0030272 | 5-formyltetrahydrofolate cyclo-ligase activity(GO:0030272) |
0.0 | 1.5 | GO:0001784 | phosphotyrosine binding(GO:0001784) |
0.0 | 0.5 | GO:0005243 | gap junction channel activity(GO:0005243) |
0.0 | 0.1 | GO:0008426 | protein kinase C inhibitor activity(GO:0008426) |
0.0 | 0.5 | GO:0015095 | magnesium ion transmembrane transporter activity(GO:0015095) |
0.0 | 0.3 | GO:0015386 | potassium:proton antiporter activity(GO:0015386) |
0.0 | 1.2 | GO:0000980 | RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980) |
0.0 | 0.5 | GO:0005248 | voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030) |
0.0 | 0.2 | GO:0008440 | inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) |
0.0 | 0.2 | GO:0004687 | myosin light chain kinase activity(GO:0004687) |
0.0 | 0.2 | GO:0070097 | delta-catenin binding(GO:0070097) |
0.0 | 0.6 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
0.0 | 0.1 | GO:0008113 | peptide-methionine (S)-S-oxide reductase activity(GO:0008113) |
0.0 | 0.9 | GO:0030291 | protein serine/threonine kinase inhibitor activity(GO:0030291) |
0.0 | 0.5 | GO:0000400 | four-way junction DNA binding(GO:0000400) |
0.0 | 0.1 | GO:0004514 | nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514) |
0.0 | 0.1 | GO:0051377 | mannose-ethanolamine phosphotransferase activity(GO:0051377) |
0.0 | 0.2 | GO:0032050 | clathrin heavy chain binding(GO:0032050) |
0.0 | 0.1 | GO:0050816 | phosphothreonine binding(GO:0050816) |
0.0 | 0.4 | GO:0008239 | dipeptidyl-peptidase activity(GO:0008239) |
0.0 | 0.3 | GO:0031078 | histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) |
0.0 | 0.2 | GO:0005068 | transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068) |
0.0 | 0.3 | GO:0035259 | glucocorticoid receptor binding(GO:0035259) |
0.0 | 0.1 | GO:0050508 | glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508) |
0.0 | 0.2 | GO:0032190 | acrosin binding(GO:0032190) |
0.0 | 0.1 | GO:0043208 | glycosphingolipid binding(GO:0043208) |
0.0 | 1.9 | GO:0003705 | transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705) |
0.0 | 0.1 | GO:0036132 | 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522) |
0.0 | 0.6 | GO:0070412 | R-SMAD binding(GO:0070412) |
0.0 | 0.1 | GO:0000217 | DNA secondary structure binding(GO:0000217) |
0.0 | 0.1 | GO:0043183 | vascular endothelial growth factor receptor 1 binding(GO:0043183) |
0.0 | 0.2 | GO:0048306 | calcium-dependent protein binding(GO:0048306) |
0.0 | 0.4 | GO:1990939 | ATP-dependent microtubule motor activity(GO:1990939) |
0.0 | 1.4 | GO:0004984 | olfactory receptor activity(GO:0004984) |
0.0 | 0.3 | GO:0047617 | acyl-CoA hydrolase activity(GO:0047617) |
0.0 | 0.1 | GO:0031728 | CCR3 chemokine receptor binding(GO:0031728) |
0.0 | 0.3 | GO:0042043 | neurexin family protein binding(GO:0042043) |
0.0 | 0.0 | GO:0005111 | type 2 fibroblast growth factor receptor binding(GO:0005111) |
0.0 | 1.0 | GO:0050840 | extracellular matrix binding(GO:0050840) |
0.0 | 0.2 | GO:0016861 | intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861) |
0.0 | 0.1 | GO:0001105 | RNA polymerase II transcription coactivator activity(GO:0001105) |
0.0 | 0.1 | GO:0016015 | morphogen activity(GO:0016015) |
0.0 | 0.6 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) |
0.0 | 0.3 | GO:0003951 | NAD+ kinase activity(GO:0003951) |
0.0 | 0.2 | GO:0008140 | cAMP response element binding protein binding(GO:0008140) |
0.0 | 0.1 | GO:0031432 | titin binding(GO:0031432) |
0.0 | 0.1 | GO:0099529 | neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315) |
0.0 | 0.1 | GO:0097371 | MDM2/MDM4 family protein binding(GO:0097371) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 3.0 | ST_G_ALPHA_S_PATHWAY | G alpha s Pathway |
0.1 | 4.6 | PID_ALPHA_SYNUCLEIN_PATHWAY | Alpha-synuclein signaling |
0.1 | 2.2 | PID_ECADHERIN_KERATINOCYTE_PATHWAY | E-cadherin signaling in keratinocytes |
0.1 | 0.9 | SA_G2_AND_M_PHASES | Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition. |
0.0 | 1.1 | PID_S1P_S1P1_PATHWAY | S1P1 pathway |
0.0 | 1.2 | PID_EPHRINB_REV_PATHWAY | Ephrin B reverse signaling |
0.0 | 2.0 | PID_HIF2PATHWAY | HIF-2-alpha transcription factor network |
0.0 | 1.5 | ST_G_ALPHA_I_PATHWAY | G alpha i Pathway |
0.0 | 1.3 | PID_P38_MK2_PATHWAY | p38 signaling mediated by MAPKAP kinases |
0.0 | 1.2 | PID_IL2_STAT5_PATHWAY | IL2 signaling events mediated by STAT5 |
0.0 | 1.1 | PID_ALK1_PATHWAY | ALK1 signaling events |
0.0 | 1.7 | PID_AJDISS_2PATHWAY | Posttranslational regulation of adherens junction stability and dissassembly |
0.0 | 0.6 | PID_DNA_PK_PATHWAY | DNA-PK pathway in nonhomologous end joining |
0.0 | 1.5 | PID_KIT_PATHWAY | Signaling events mediated by Stem cell factor receptor (c-Kit) |
0.0 | 1.5 | PID_HEDGEHOG_GLI_PATHWAY | Hedgehog signaling events mediated by Gli proteins |
0.0 | 6.0 | NABA_ECM_GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
0.0 | 0.4 | SA_G1_AND_S_PHASES | Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition. |
0.0 | 0.1 | PID_IL5_PATHWAY | IL5-mediated signaling events |
0.0 | 0.2 | PID_PDGFRA_PATHWAY | PDGFR-alpha signaling pathway |
0.0 | 0.8 | PID_NETRIN_PATHWAY | Netrin-mediated signaling events |
0.0 | 0.5 | PID_CONE_PATHWAY | Visual signal transduction: Cones |
0.0 | 0.3 | PID_CIRCADIAN_PATHWAY | Circadian rhythm pathway |
0.0 | 1.1 | PID_P53_REGULATION_PATHWAY | p53 pathway |
0.0 | 0.2 | PID_P38_GAMMA_DELTA_PATHWAY | Signaling mediated by p38-gamma and p38-delta |
0.0 | 0.4 | PID_EPHA_FWDPATHWAY | EPHA forward signaling |
0.0 | 1.1 | PID_HIF1_TFPATHWAY | HIF-1-alpha transcription factor network |
0.0 | 1.0 | PID_ILK_PATHWAY | Integrin-linked kinase signaling |
0.0 | 0.5 | PID_IL6_7_PATHWAY | IL6-mediated signaling events |
Gene overrepresentation in C2:CP:REACTOME category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 2.5 | REACTOME_TRYPTOPHAN_CATABOLISM | Genes involved in Tryptophan catabolism |
0.1 | 2.9 | REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
0.1 | 1.2 | REACTOME_GLYCOPROTEIN_HORMONES | Genes involved in Glycoprotein hormones |
0.1 | 3.8 | REACTOME_RAP1_SIGNALLING | Genes involved in Rap1 signalling |
0.1 | 3.6 | REACTOME_SMOOTH_MUSCLE_CONTRACTION | Genes involved in Smooth Muscle Contraction |
0.1 | 0.4 | REACTOME_INHIBITION_OF_INSULIN_SECRETION_BY_ADRENALINE_NORADRENALINE | Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline |
0.0 | 0.8 | REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS | Genes involved in Presynaptic nicotinic acetylcholine receptors |
0.0 | 0.2 | REACTOME_INHIBITION_OF_REPLICATION_INITIATION_OF_DAMAGED_DNA_BY_RB1_E2F1 | Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1 |
0.0 | 0.3 | REACTOME_CROSS_PRESENTATION_OF_SOLUBLE_EXOGENOUS_ANTIGENS_ENDOSOMES | Genes involved in Cross-presentation of soluble exogenous antigens (endosomes) |
0.0 | 2.0 | REACTOME_RECYCLING_PATHWAY_OF_L1 | Genes involved in Recycling pathway of L1 |
0.0 | 1.4 | REACTOME_STEROID_HORMONES | Genes involved in Steroid hormones |
0.0 | 1.9 | REACTOME_REGULATION_OF_HYPOXIA_INDUCIBLE_FACTOR_HIF_BY_OXYGEN | Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen |
0.0 | 1.2 | REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS | Genes involved in Regulation of gene expression in beta cells |
0.0 | 0.6 | REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS | Genes involved in Activation of the AP-1 family of transcription factors |
0.0 | 1.3 | REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS | Genes involved in Association of TriC/CCT with target proteins during biosynthesis |
0.0 | 0.9 | REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION | Genes involved in Cyclin A/B1 associated events during G2/M transition |
0.0 | 0.3 | REACTOME_COPI_MEDIATED_TRANSPORT | Genes involved in COPI Mediated Transport |
0.0 | 1.8 | REACTOME_G_ALPHA_Z_SIGNALLING_EVENTS | Genes involved in G alpha (z) signalling events |
0.0 | 0.5 | REACTOME_INTRINSIC_PATHWAY | Genes involved in Intrinsic Pathway |
0.0 | 1.0 | REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS | Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus |
0.0 | 1.4 | REACTOME_G1_PHASE | Genes involved in G1 Phase |
0.0 | 1.4 | REACTOME_GLUCONEOGENESIS | Genes involved in Gluconeogenesis |
0.0 | 0.5 | REACTOME_GAP_JUNCTION_ASSEMBLY | Genes involved in Gap junction assembly |
0.0 | 0.8 | REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES | Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates |
0.0 | 0.5 | REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI | Genes involved in Pre-NOTCH Processing in Golgi |
0.0 | 0.3 | REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS | Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis |
0.0 | 0.4 | REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE | Genes involved in Acetylcholine Neurotransmitter Release Cycle |
0.0 | 0.8 | REACTOME_HS_GAG_BIOSYNTHESIS | Genes involved in HS-GAG biosynthesis |
0.0 | 0.2 | REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN | Genes involved in Platelet Adhesion to exposed collagen |
0.0 | 0.5 | REACTOME_CA_DEPENDENT_EVENTS | Genes involved in Ca-dependent events |
0.0 | 1.6 | REACTOME_OLFACTORY_SIGNALING_PATHWAY | Genes involved in Olfactory Signaling Pathway |
0.0 | 0.6 | REACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING | Genes involved in Downregulation of TGF-beta receptor signaling |
0.0 | 0.3 | REACTOME_REGULATION_OF_SIGNALING_BY_CBL | Genes involved in Regulation of signaling by CBL |
0.0 | 0.5 | REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX | Genes involved in Degradation of the extracellular matrix |
0.0 | 0.6 | REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS | Genes involved in Caspase-mediated cleavage of cytoskeletal proteins |
0.0 | 0.5 | REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
0.0 | 0.8 | REACTOME_CD28_CO_STIMULATION | Genes involved in CD28 co-stimulation |
0.0 | 0.3 | REACTOME_SEMA3A_PAK_DEPENDENT_AXON_REPULSION | Genes involved in Sema3A PAK dependent Axon repulsion |
0.0 | 0.1 | REACTOME_IRAK2_MEDIATED_ACTIVATION_OF_TAK1_COMPLEX_UPON_TLR7_8_OR_9_STIMULATION | Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation |
0.0 | 1.0 | REACTOME_ACTIVATION_OF_NF_KAPPAB_IN_B_CELLS | Genes involved in Activation of NF-kappaB in B Cells |
0.0 | 0.2 | REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN | Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin |
0.0 | 0.3 | REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE | Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere |