Motif ID: OTX1
Z-value: 0.714

Transcription factors associated with OTX1:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
OTX1 | ENSG00000115507.5 | OTX1 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
OTX1 | hg19_v2_chr2_+_63277927_63277938 | 0.57 | 3.3e-03 | Click! |
Top targets:
Showing 1 to 20 of 196 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 57 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 8.3 | GO:0044458 | motile cilium assembly(GO:0044458) |
0.1 | 3.5 | GO:0043252 | sodium-independent organic anion transport(GO:0043252) |
0.0 | 2.3 | GO:1900047 | negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047) |
0.5 | 1.5 | GO:2000661 | positive regulation of interleukin-1-mediated signaling pathway(GO:2000661) |
0.2 | 1.4 | GO:2000124 | regulation of endocannabinoid signaling pathway(GO:2000124) |
0.0 | 1.3 | GO:0048247 | lymphocyte chemotaxis(GO:0048247) |
0.1 | 1.2 | GO:0006020 | inositol metabolic process(GO:0006020) |
0.0 | 1.2 | GO:0035338 | long-chain fatty-acyl-CoA biosynthetic process(GO:0035338) |
0.2 | 1.0 | GO:0007181 | transforming growth factor beta receptor complex assembly(GO:0007181) |
0.0 | 0.9 | GO:0097094 | craniofacial suture morphogenesis(GO:0097094) |
0.0 | 0.9 | GO:0006120 | mitochondrial electron transport, NADH to ubiquinone(GO:0006120) |
0.0 | 0.8 | GO:0010842 | retina layer formation(GO:0010842) |
0.1 | 0.7 | GO:2001106 | regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106) |
0.0 | 0.7 | GO:1901620 | regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901620) |
0.0 | 0.6 | GO:0046069 | cGMP catabolic process(GO:0046069) |
0.0 | 0.6 | GO:0006957 | complement activation, alternative pathway(GO:0006957) |
0.0 | 0.6 | GO:0048012 | hepatocyte growth factor receptor signaling pathway(GO:0048012) |
0.0 | 0.6 | GO:0031954 | positive regulation of protein autophosphorylation(GO:0031954) |
0.2 | 0.5 | GO:0002752 | cell surface pattern recognition receptor signaling pathway(GO:0002752) |
0.0 | 0.5 | GO:0032466 | negative regulation of cytokinesis(GO:0032466) |
Gene overrepresentation in cellular_component category:
Showing 1 to 20 of 23 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 2.5 | GO:0005902 | microvillus(GO:0005902) |
0.0 | 1.4 | GO:0032281 | AMPA glutamate receptor complex(GO:0032281) |
0.2 | 1.0 | GO:0034673 | inhibin-betaglycan-ActRII complex(GO:0034673) |
0.1 | 1.0 | GO:0034464 | BBSome(GO:0034464) |
0.0 | 0.9 | GO:0045271 | mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271) |
0.0 | 0.6 | GO:0000177 | cytoplasmic exosome (RNase complex)(GO:0000177) |
0.0 | 0.6 | GO:1902911 | protein kinase complex(GO:1902911) |
0.0 | 0.6 | GO:0030867 | rough endoplasmic reticulum membrane(GO:0030867) |
0.0 | 0.6 | GO:0097546 | ciliary base(GO:0097546) |
0.0 | 0.5 | GO:0071682 | endocytic vesicle lumen(GO:0071682) |
0.1 | 0.4 | GO:1990357 | terminal web(GO:1990357) |
0.0 | 0.4 | GO:0045275 | mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275) |
0.0 | 0.4 | GO:0032039 | integrator complex(GO:0032039) |
0.0 | 0.4 | GO:0046540 | U4/U6 x U5 tri-snRNP complex(GO:0046540) |
0.0 | 0.3 | GO:0097025 | MPP7-DLG1-LIN7 complex(GO:0097025) |
0.0 | 0.3 | GO:0000813 | ESCRT I complex(GO:0000813) |
0.0 | 0.3 | GO:0000276 | mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276) |
0.0 | 0.2 | GO:0005944 | phosphatidylinositol 3-kinase complex, class IB(GO:0005944) |
0.0 | 0.2 | GO:0036128 | CatSper complex(GO:0036128) |
0.0 | 0.2 | GO:0072546 | ER membrane protein complex(GO:0072546) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 36 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 3.5 | GO:0015125 | bile acid transmembrane transporter activity(GO:0015125) |
0.2 | 1.7 | GO:0004499 | N,N-dimethylaniline monooxygenase activity(GO:0004499) |
0.0 | 1.6 | GO:0005388 | calcium-transporting ATPase activity(GO:0005388) |
0.4 | 1.5 | GO:0004909 | interleukin-1, Type I, activating receptor activity(GO:0004909) |
0.0 | 1.5 | GO:0032266 | phosphatidylinositol-3-phosphate binding(GO:0032266) |
0.1 | 1.4 | GO:0047372 | acylglycerol lipase activity(GO:0047372) |
0.0 | 1.3 | GO:0048020 | CCR chemokine receptor binding(GO:0048020) |
0.2 | 1.2 | GO:0033857 | diphosphoinositol-pentakisphosphate kinase activity(GO:0033857) |
0.1 | 1.2 | GO:0102391 | decanoate--CoA ligase activity(GO:0102391) |
0.2 | 1.1 | GO:0004999 | vasoactive intestinal polypeptide receptor activity(GO:0004999) |
0.1 | 1.0 | GO:0005114 | type II transforming growth factor beta receptor binding(GO:0005114) |
0.0 | 1.0 | GO:0004114 | 3',5'-cyclic-nucleotide phosphodiesterase activity(GO:0004114) |
0.0 | 0.9 | GO:0050136 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
0.0 | 0.8 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
0.0 | 0.6 | GO:0043395 | heparan sulfate proteoglycan binding(GO:0043395) |
0.1 | 0.5 | GO:0008142 | oxysterol binding(GO:0008142) |
0.1 | 0.4 | GO:0016300 | tRNA (uracil) methyltransferase activity(GO:0016300) |
0.1 | 0.4 | GO:0008121 | ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681) |
0.0 | 0.4 | GO:0034450 | ubiquitin-ubiquitin ligase activity(GO:0034450) |
0.0 | 0.3 | GO:0042030 | ATPase inhibitor activity(GO:0042030) |
Gene overrepresentation in C2:CP category:
Showing 1 to 5 of 5 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 1.5 | ST_JNK_MAPK_PATHWAY | JNK MAPK Pathway |
0.0 | 1.3 | ST_ADRENERGIC | Adrenergic Pathway |
0.0 | 0.9 | PID_AR_TF_PATHWAY | Regulation of Androgen receptor activity |
0.0 | 0.7 | ST_WNT_BETA_CATENIN_PATHWAY | Wnt/beta-catenin Pathway |
0.0 | 0.2 | ST_INTERFERON_GAMMA_PATHWAY | Interferon gamma pathway. |
Gene overrepresentation in C2:CP:REACTOME category:
Showing 1 to 14 of 14 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 3.5 | REACTOME_RECYCLING_OF_BILE_ACIDS_AND_SALTS | Genes involved in Recycling of bile acids and salts |
0.0 | 1.5 | REACTOME_IL1_SIGNALING | Genes involved in Interleukin-1 signaling |
0.0 | 1.2 | REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS | Genes involved in Synthesis of very long-chain fatty acyl-CoAs |
0.0 | 1.1 | REACTOME_GLUCAGON_TYPE_LIGAND_RECEPTORS | Genes involved in Glucagon-type ligand receptors |
0.0 | 1.0 | REACTOME_INTERFERON_ALPHA_BETA_SIGNALING | Genes involved in Interferon alpha/beta signaling |
0.0 | 0.6 | REACTOME_REGULATION_OF_COMPLEMENT_CASCADE | Genes involved in Regulation of Complement cascade |
0.0 | 0.5 | REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA | Genes involved in Circadian Repression of Expression by REV-ERBA |
0.0 | 0.5 | REACTOME_CGMP_EFFECTS | Genes involved in cGMP effects |
0.0 | 0.3 | REACTOME_MEMBRANE_BINDING_AND_TARGETTING_OF_GAG_PROTEINS | Genes involved in Membrane binding and targetting of GAG proteins |
0.0 | 0.3 | REACTOME_IL_7_SIGNALING | Genes involved in Interleukin-7 signaling |
0.0 | 0.2 | REACTOME_REGULATION_OF_IFNG_SIGNALING | Genes involved in Regulation of IFNG signaling |
0.0 | 0.2 | REACTOME_MRNA_DECAY_BY_3_TO_5_EXORIBONUCLEASE | Genes involved in mRNA Decay by 3' to 5' Exoribonuclease |
0.0 | 0.2 | REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION | Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation |
0.0 | 0.2 | REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PI3KGAMMA | Genes involved in G beta:gamma signalling through PI3Kgamma |