Motif ID: PAX7_NOBOX
Z-value: 0.567
Transcription factors associated with PAX7_NOBOX:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
NOBOX | ENSG00000106410.10 | NOBOX |
PAX7 | ENSG00000009709.7 | PAX7 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
NOBOX | hg19_v2_chr7_-_144107320_144107320 | -0.36 | 8.6e-02 | Click! |
PAX7 | hg19_v2_chr1_+_18957500_18957623 | -0.15 | 4.8e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 0.7 | GO:0010430 | fatty acid omega-oxidation(GO:0010430) |
0.2 | 0.5 | GO:0071284 | cellular response to lead ion(GO:0071284) |
0.2 | 0.9 | GO:0031022 | nuclear migration along microfilament(GO:0031022) |
0.1 | 0.6 | GO:0072299 | negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302) |
0.1 | 2.0 | GO:0060294 | cilium movement involved in cell motility(GO:0060294) |
0.1 | 0.4 | GO:0030505 | inorganic diphosphate transport(GO:0030505) |
0.1 | 0.1 | GO:0003356 | regulation of cilium beat frequency(GO:0003356) |
0.1 | 0.3 | GO:0071139 | resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140) |
0.1 | 0.3 | GO:0060434 | bronchus morphogenesis(GO:0060434) |
0.1 | 0.7 | GO:0002414 | immunoglobulin transcytosis in epithelial cells(GO:0002414) |
0.1 | 0.3 | GO:0061358 | negative regulation of Wnt protein secretion(GO:0061358) |
0.1 | 0.1 | GO:0006574 | valine catabolic process(GO:0006574) |
0.1 | 0.2 | GO:0051097 | negative regulation of helicase activity(GO:0051097) |
0.1 | 0.2 | GO:0051758 | homologous chromosome movement towards spindle pole involved in homologous chromosome segregation(GO:0051758) |
0.1 | 0.1 | GO:0050787 | detoxification of mercury ion(GO:0050787) |
0.1 | 0.2 | GO:2000866 | positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866) |
0.1 | 0.1 | GO:0007171 | activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171) |
0.1 | 0.2 | GO:0032053 | ciliary basal body organization(GO:0032053) |
0.1 | 0.3 | GO:0060005 | vestibular reflex(GO:0060005) |
0.1 | 0.2 | GO:0031247 | actin rod assembly(GO:0031247) |
0.1 | 0.2 | GO:0032747 | positive regulation of interleukin-23 production(GO:0032747) |
0.1 | 0.3 | GO:0048496 | maintenance of organ identity(GO:0048496) |
0.1 | 2.0 | GO:0071801 | regulation of podosome assembly(GO:0071801) |
0.1 | 0.4 | GO:1901419 | regulation of response to alcohol(GO:1901419) |
0.1 | 0.2 | GO:0007181 | transforming growth factor beta receptor complex assembly(GO:0007181) |
0.0 | 0.5 | GO:0015889 | cobalamin transport(GO:0015889) |
0.0 | 0.2 | GO:0060406 | positive regulation of penile erection(GO:0060406) |
0.0 | 1.2 | GO:0097067 | cellular response to thyroid hormone stimulus(GO:0097067) |
0.0 | 0.1 | GO:0060490 | dichotomous subdivision of terminal units involved in lung branching(GO:0060448) orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490) non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346) |
0.0 | 0.4 | GO:0006686 | sphingomyelin biosynthetic process(GO:0006686) |
0.0 | 0.9 | GO:0072643 | interferon-gamma secretion(GO:0072643) |
0.0 | 0.3 | GO:0090080 | positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080) |
0.0 | 0.6 | GO:0043248 | proteasome assembly(GO:0043248) |
0.0 | 0.5 | GO:0001833 | inner cell mass cell proliferation(GO:0001833) |
0.0 | 0.2 | GO:0070092 | regulation of glucagon secretion(GO:0070092) |
0.0 | 0.4 | GO:0006069 | ethanol oxidation(GO:0006069) |
0.0 | 0.1 | GO:0035425 | autocrine signaling(GO:0035425) |
0.0 | 0.2 | GO:0038161 | prolactin signaling pathway(GO:0038161) |
0.0 | 0.2 | GO:0042746 | regulation of circadian sleep/wake cycle, wakefulness(GO:0010840) circadian sleep/wake cycle, wakefulness(GO:0042746) |
0.0 | 0.1 | GO:1902725 | negative regulation of satellite cell differentiation(GO:1902725) |
0.0 | 0.1 | GO:1904247 | positive regulation of polynucleotide adenylyltransferase activity(GO:1904247) |
0.0 | 0.1 | GO:0021577 | hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589) |
0.0 | 0.1 | GO:0010716 | negative regulation of extracellular matrix disassembly(GO:0010716) |
0.0 | 0.2 | GO:0097428 | protein maturation by iron-sulfur cluster transfer(GO:0097428) |
0.0 | 0.2 | GO:0051725 | protein de-ADP-ribosylation(GO:0051725) |
0.0 | 0.2 | GO:1901668 | regulation of superoxide dismutase activity(GO:1901668) |
0.0 | 0.1 | GO:1901503 | ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503) |
0.0 | 0.2 | GO:0034551 | respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033) |
0.0 | 0.5 | GO:0006068 | ethanol metabolic process(GO:0006067) ethanol catabolic process(GO:0006068) |
0.0 | 0.2 | GO:0061669 | spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814) |
0.0 | 0.5 | GO:0044458 | motile cilium assembly(GO:0044458) |
0.0 | 0.2 | GO:0006880 | intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577) |
0.0 | 0.2 | GO:0039663 | fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800) |
0.0 | 0.2 | GO:0055059 | asymmetric neuroblast division(GO:0055059) |
0.0 | 0.2 | GO:0070779 | D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779) |
0.0 | 0.2 | GO:2000253 | positive regulation of feeding behavior(GO:2000253) |
0.0 | 0.1 | GO:0021784 | postganglionic parasympathetic fiber development(GO:0021784) regulation of ureteric bud formation(GO:0072106) positive regulation of ureteric bud formation(GO:0072107) |
0.0 | 0.2 | GO:0006657 | CDP-choline pathway(GO:0006657) |
0.0 | 0.2 | GO:0006552 | leucine catabolic process(GO:0006552) |
0.0 | 0.6 | GO:0070286 | axonemal dynein complex assembly(GO:0070286) |
0.0 | 0.2 | GO:0019317 | fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355) |
0.0 | 0.1 | GO:0002074 | extraocular skeletal muscle development(GO:0002074) |
0.0 | 0.3 | GO:0045792 | negative regulation of cell size(GO:0045792) |
0.0 | 0.1 | GO:0045875 | negative regulation of sister chromatid cohesion(GO:0045875) protein auto-ADP-ribosylation(GO:0070213) |
0.0 | 0.6 | GO:0061157 | mRNA destabilization(GO:0061157) |
0.0 | 0.1 | GO:0003218 | cardiac left ventricle formation(GO:0003218) |
0.0 | 0.1 | GO:0051970 | negative regulation of transmission of nerve impulse(GO:0051970) |
0.0 | 0.2 | GO:0016255 | attachment of GPI anchor to protein(GO:0016255) |
0.0 | 0.1 | GO:0032474 | otolith morphogenesis(GO:0032474) |
0.0 | 0.1 | GO:0071896 | protein localization to adherens junction(GO:0071896) |
0.0 | 0.4 | GO:0052695 | cellular glucuronidation(GO:0052695) |
0.0 | 0.1 | GO:1900113 | negative regulation of histone H3-K9 trimethylation(GO:1900113) |
0.0 | 0.2 | GO:0032277 | negative regulation of gonadotropin secretion(GO:0032277) |
0.0 | 0.1 | GO:0070105 | positive regulation of interleukin-6-mediated signaling pathway(GO:0070105) |
0.0 | 0.2 | GO:0045176 | apical protein localization(GO:0045176) |
0.0 | 0.1 | GO:0000038 | very long-chain fatty acid metabolic process(GO:0000038) |
0.0 | 0.2 | GO:0018206 | peptidyl-methionine modification(GO:0018206) |
0.0 | 0.3 | GO:0046548 | retinal rod cell development(GO:0046548) |
0.0 | 0.0 | GO:1904383 | response to sodium phosphate(GO:1904383) |
0.0 | 0.1 | GO:0001550 | ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165) |
0.0 | 0.1 | GO:1901098 | positive regulation of autophagosome maturation(GO:1901098) |
0.0 | 0.3 | GO:0030335 | positive regulation of cell migration(GO:0030335) |
0.0 | 0.1 | GO:0019509 | L-methionine biosynthetic process from methylthioadenosine(GO:0019509) |
0.0 | 0.2 | GO:0034501 | protein localization to kinetochore(GO:0034501) |
0.0 | 0.4 | GO:0030220 | platelet formation(GO:0030220) |
0.0 | 0.5 | GO:0045730 | respiratory burst(GO:0045730) |
0.0 | 0.1 | GO:0000066 | mitochondrial ornithine transport(GO:0000066) |
0.0 | 0.1 | GO:0032218 | riboflavin transport(GO:0032218) |
0.0 | 0.1 | GO:0048254 | snoRNA localization(GO:0048254) |
0.0 | 0.0 | GO:0060823 | canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060823) |
0.0 | 0.3 | GO:0051457 | maintenance of protein location in nucleus(GO:0051457) |
0.0 | 0.2 | GO:1903504 | regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504) |
0.0 | 0.1 | GO:0010793 | regulation of mRNA export from nucleus(GO:0010793) |
0.0 | 0.0 | GO:1903644 | regulation of chaperone-mediated protein folding(GO:1903644) |
0.0 | 0.0 | GO:0060369 | positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369) |
0.0 | 0.0 | GO:0010730 | negative regulation of hydrogen peroxide biosynthetic process(GO:0010730) |
0.0 | 0.0 | GO:0061743 | motor learning(GO:0061743) |
0.0 | 0.2 | GO:0008340 | determination of adult lifespan(GO:0008340) |
0.0 | 0.1 | GO:0008582 | acetylcholine catabolic process in synaptic cleft(GO:0001507) acetylcholine catabolic process(GO:0006581) regulation of synaptic growth at neuromuscular junction(GO:0008582) |
0.0 | 0.0 | GO:0000454 | snoRNA guided rRNA pseudouridine synthesis(GO:0000454) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 0.5 | GO:0097224 | sperm connecting piece(GO:0097224) |
0.1 | 0.5 | GO:0097196 | Shu complex(GO:0097196) |
0.1 | 0.5 | GO:0032010 | phagolysosome(GO:0032010) |
0.1 | 0.5 | GO:0031232 | extrinsic component of external side of plasma membrane(GO:0031232) |
0.1 | 0.4 | GO:0036021 | endolysosome lumen(GO:0036021) |
0.1 | 0.3 | GO:0005726 | perichromatin fibrils(GO:0005726) |
0.1 | 0.2 | GO:0034673 | inhibin-betaglycan-ActRII complex(GO:0034673) |
0.0 | 0.9 | GO:0034993 | microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993) |
0.0 | 0.5 | GO:0043240 | Fanconi anaemia nuclear complex(GO:0043240) |
0.0 | 0.2 | GO:0000444 | MIS12/MIND type complex(GO:0000444) |
0.0 | 0.1 | GO:0005863 | striated muscle myosin thick filament(GO:0005863) |
0.0 | 0.3 | GO:0033063 | Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063) |
0.0 | 0.1 | GO:0036477 | somatodendritic compartment(GO:0036477) |
0.0 | 0.3 | GO:0030991 | intraciliary transport particle A(GO:0030991) |
0.0 | 0.2 | GO:0042765 | GPI-anchor transamidase complex(GO:0042765) |
0.0 | 0.2 | GO:0016035 | zeta DNA polymerase complex(GO:0016035) |
0.0 | 1.9 | GO:0002102 | podosome(GO:0002102) |
0.0 | 0.3 | GO:0036157 | outer dynein arm(GO:0036157) |
0.0 | 0.1 | GO:0060187 | cell pole(GO:0060187) |
0.0 | 0.2 | GO:0044326 | dendritic spine neck(GO:0044326) |
0.0 | 0.3 | GO:0033588 | Elongator holoenzyme complex(GO:0033588) |
0.0 | 0.2 | GO:1990130 | Iml1 complex(GO:1990130) |
0.0 | 0.2 | GO:0097504 | Gemini of coiled bodies(GO:0097504) |
0.0 | 0.2 | GO:0016013 | syntrophin complex(GO:0016013) |
0.0 | 0.3 | GO:0030914 | STAGA complex(GO:0030914) |
0.0 | 0.2 | GO:0046581 | intercellular canaliculus(GO:0046581) |
0.0 | 2.1 | GO:0097014 | axoneme(GO:0005930) ciliary plasm(GO:0097014) |
0.0 | 0.2 | GO:0070938 | contractile ring(GO:0070938) |
0.0 | 0.3 | GO:0097539 | ciliary transition fiber(GO:0097539) |
0.0 | 0.1 | GO:0097125 | cyclin B1-CDK1 complex(GO:0097125) |
0.0 | 0.1 | GO:0005687 | U4 snRNP(GO:0005687) |
0.0 | 0.0 | GO:0005588 | collagen type V trimer(GO:0005588) |
0.0 | 0.2 | GO:0031618 | nuclear pericentric heterochromatin(GO:0031618) |
0.0 | 0.4 | GO:0097228 | sperm principal piece(GO:0097228) |
0.0 | 0.2 | GO:0070776 | H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776) |
0.0 | 0.2 | GO:0044615 | nuclear pore nuclear basket(GO:0044615) |
0.0 | 0.3 | GO:0032391 | photoreceptor connecting cilium(GO:0032391) |
0.0 | 0.1 | GO:0097025 | MPP7-DLG1-LIN7 complex(GO:0097025) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 0.7 | GO:0019770 | IgG receptor activity(GO:0019770) |
0.2 | 0.5 | GO:0032767 | copper-dependent protein binding(GO:0032767) |
0.2 | 0.7 | GO:0004031 | aldehyde oxidase activity(GO:0004031) |
0.1 | 0.6 | GO:0044729 | hemi-methylated DNA-binding(GO:0044729) |
0.1 | 0.8 | GO:0004301 | epoxide hydrolase activity(GO:0004301) |
0.1 | 0.8 | GO:0008568 | microtubule-severing ATPase activity(GO:0008568) |
0.1 | 0.4 | GO:0004024 | alcohol dehydrogenase activity, zinc-dependent(GO:0004024) |
0.1 | 0.3 | GO:0038047 | beta-endorphin receptor activity(GO:0004979) morphine receptor activity(GO:0038047) |
0.1 | 0.5 | GO:0050294 | flavonol 3-sulfotransferase activity(GO:0047894) steroid sulfotransferase activity(GO:0050294) |
0.1 | 0.4 | GO:0033188 | sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493) |
0.1 | 0.3 | GO:0004566 | beta-glucuronidase activity(GO:0004566) |
0.1 | 0.3 | GO:0008336 | gamma-butyrobetaine dioxygenase activity(GO:0008336) |
0.1 | 0.3 | GO:0035529 | NADH pyrophosphatase activity(GO:0035529) |
0.1 | 0.2 | GO:0031685 | adenosine receptor binding(GO:0031685) |
0.1 | 0.2 | GO:0047273 | galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273) |
0.0 | 0.1 | GO:0010309 | acireductone dioxygenase [iron(II)-requiring] activity(GO:0010309) |
0.0 | 0.2 | GO:0004105 | choline-phosphate cytidylyltransferase activity(GO:0004105) |
0.0 | 1.3 | GO:0045505 | dynein intermediate chain binding(GO:0045505) |
0.0 | 0.5 | GO:0031419 | cobalamin binding(GO:0031419) |
0.0 | 0.2 | GO:0016499 | orexin receptor activity(GO:0016499) |
0.0 | 0.2 | GO:0098519 | nucleotide phosphatase activity, acting on free nucleotides(GO:0098519) |
0.0 | 0.5 | GO:0016176 | superoxide-generating NADPH oxidase activator activity(GO:0016176) |
0.0 | 0.5 | GO:0032027 | myosin light chain binding(GO:0032027) |
0.0 | 0.2 | GO:0004925 | prolactin receptor activity(GO:0004925) |
0.0 | 0.2 | GO:0003923 | GPI-anchor transamidase activity(GO:0003923) |
0.0 | 0.7 | GO:0070330 | aromatase activity(GO:0070330) |
0.0 | 0.3 | GO:0008821 | crossover junction endodeoxyribonuclease activity(GO:0008821) |
0.0 | 0.2 | GO:0004064 | arylesterase activity(GO:0004064) |
0.0 | 0.1 | GO:0004803 | transposase activity(GO:0004803) |
0.0 | 0.2 | GO:0015501 | glutamate:sodium symporter activity(GO:0015501) |
0.0 | 0.3 | GO:0034056 | estrogen response element binding(GO:0034056) |
0.0 | 2.1 | GO:0003777 | microtubule motor activity(GO:0003777) |
0.0 | 0.1 | GO:0050309 | glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309) |
0.0 | 0.1 | GO:0030021 | extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345) |
0.0 | 0.2 | GO:0005114 | type II transforming growth factor beta receptor binding(GO:0005114) |
0.0 | 0.2 | GO:0005005 | transmembrane-ephrin receptor activity(GO:0005005) |
0.0 | 0.1 | GO:0008449 | N-acetylglucosamine-6-sulfatase activity(GO:0008449) |
0.0 | 0.3 | GO:0003995 | acyl-CoA dehydrogenase activity(GO:0003995) |
0.0 | 0.2 | GO:0019957 | C-C chemokine binding(GO:0019957) |
0.0 | 0.2 | GO:0008417 | fucosyltransferase activity(GO:0008417) |
0.0 | 0.1 | GO:0000268 | peroxisome targeting sequence binding(GO:0000268) |
0.0 | 0.1 | GO:0004739 | pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739) |
0.0 | 0.1 | GO:0008431 | vitamin E binding(GO:0008431) |
0.0 | 0.1 | GO:0051864 | histone demethylase activity (H3-K36 specific)(GO:0051864) |
0.0 | 0.8 | GO:0043425 | bHLH transcription factor binding(GO:0043425) |
0.0 | 0.1 | GO:0000064 | L-ornithine transmembrane transporter activity(GO:0000064) |
0.0 | 0.1 | GO:0032217 | riboflavin transporter activity(GO:0032217) |
0.0 | 0.5 | GO:0015020 | glucuronosyltransferase activity(GO:0015020) |
0.0 | 0.3 | GO:0016289 | CoA hydrolase activity(GO:0016289) |
0.0 | 0.1 | GO:0005025 | transforming growth factor beta receptor activity, type I(GO:0005025) |
0.0 | 0.4 | GO:0001968 | fibronectin binding(GO:0001968) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 0.8 | PID_FANCONI_PATHWAY | Fanconi anemia pathway |
Gene overrepresentation in C2:CP:REACTOME category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 1.1 | REACTOME_ETHANOL_OXIDATION | Genes involved in Ethanol oxidation |
0.1 | 2.1 | REACTOME_KINESINS | Genes involved in Kinesins |
0.0 | 0.4 | REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY | Genes involved in Endosomal/Vacuolar pathway |
0.0 | 0.8 | REACTOME_RETROGRADE_NEUROTROPHIN_SIGNALLING | Genes involved in Retrograde neurotrophin signalling |
0.0 | 0.2 | REACTOME_BINDING_AND_ENTRY_OF_HIV_VIRION | Genes involved in Binding and entry of HIV virion |
0.0 | 0.7 | REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS | Genes involved in Termination of O-glycan biosynthesis |
0.0 | 0.5 | REACTOME_GLUCURONIDATION | Genes involved in Glucuronidation |
0.0 | 0.5 | REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES | Genes involved in Cytosolic sulfonation of small molecules |
0.0 | 0.4 | REACTOME_HDL_MEDIATED_LIPID_TRANSPORT | Genes involved in HDL-mediated lipid transport |
0.0 | 0.5 | REACTOME_FANCONI_ANEMIA_PATHWAY | Genes involved in Fanconi Anemia pathway |
0.0 | 0.1 | REACTOME_COMMON_PATHWAY | Genes involved in Common Pathway |
0.0 | 0.2 | REACTOME_REVERSIBLE_HYDRATION_OF_CARBON_DIOXIDE | Genes involved in Reversible Hydration of Carbon Dioxide |
0.0 | 0.2 | REACTOME_P2Y_RECEPTORS | Genes involved in P2Y receptors |