Motif ID: PAX8

Z-value: 0.361


Transcription factors associated with PAX8:

Gene SymbolEntrez IDGene Name
PAX8 ENSG00000125618.12 PAX8

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
PAX8hg19_v2_chr2_-_113999260_1139992740.414.7e-02Click!


Activity profile for motif PAX8.

activity profile for motif PAX8


Sorted Z-values histogram for motif PAX8

Sorted Z-values for motif PAX8



Network of associatons between targets according to the STRING database.



First level regulatory network of PAX8

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_-_51487282 0.701 ENST00000595820.1
ENST00000597707.1
ENST00000336317.4
KLK7


kallikrein-related peptidase 7


chr19_-_36019123 0.510 ENST00000588674.1
ENST00000452271.2
ENST00000518157.1
SBSN


suprabasin


chr4_+_75230853 0.497 ENST00000244869.2
EREG
epiregulin
chr1_-_153013588 0.442 ENST00000360379.3
SPRR2D
small proline-rich protein 2D
chr19_-_51537982 0.432 ENST00000525263.1
KLK12
kallikrein-related peptidase 12
chr6_+_31126291 0.423 ENST00000376257.3
ENST00000376255.4
TCF19

transcription factor 19

chr19_-_51538118 0.413 ENST00000529888.1
KLK12
kallikrein-related peptidase 12
chr2_-_234763147 0.407 ENST00000411486.2
ENST00000432087.1
ENST00000441687.1
ENST00000414924.1
HJURP



Holliday junction recognition protein



chr19_-_51538148 0.402 ENST00000319590.4
ENST00000250351.4
KLK12

kallikrein-related peptidase 12

chr5_+_148521136 0.368 ENST00000506113.1
ABLIM3
actin binding LIM protein family, member 3
chr11_-_58343319 0.342 ENST00000395074.2
LPXN
leupaxin
chr17_-_39216344 0.337 ENST00000391418.2
KRTAP2-3
keratin associated protein 2-3
chr12_+_75874460 0.335 ENST00000266659.3
GLIPR1
GLI pathogenesis-related 1
chr7_-_97501706 0.312 ENST00000455086.1
ENST00000453600.1
ASNS

asparagine synthetase (glutamine-hydrolyzing)

chr1_+_13359819 0.297 ENST00000376168.1
PRAMEF5
PRAME family member 5
chr22_-_37403839 0.291 ENST00000402860.3
ENST00000381821.1
TEX33

testis expressed 33

chr22_-_37403858 0.290 ENST00000405091.2
TEX33
testis expressed 33
chr10_+_135340859 0.282 ENST00000252945.3
ENST00000421586.1
ENST00000418356.1
CYP2E1


cytochrome P450, family 2, subfamily E, polypeptide 1


chr12_-_6961050 0.275 ENST00000538862.2
CDCA3
cell division cycle associated 3
chr12_-_6960407 0.272 ENST00000540683.1
ENST00000229265.6
ENST00000535406.1
ENST00000422785.3
CDCA3



cell division cycle associated 3



chr7_-_76255444 0.266 ENST00000454397.1
POMZP3
POM121 and ZP3 fusion
chr19_-_35992780 0.253 ENST00000593342.1
ENST00000601650.1
ENST00000408915.2
DMKN


dermokine


chr16_-_28518153 0.253 ENST00000356897.1
IL27
interleukin 27
chr3_+_121796697 0.238 ENST00000482356.1
ENST00000393627.2
CD86

CD86 molecule

chr1_-_214638146 0.237 ENST00000543945.1
PTPN14
protein tyrosine phosphatase, non-receptor type 14
chr18_-_58040000 0.222 ENST00000299766.3
MC4R
melanocortin 4 receptor
chr8_+_27168988 0.217 ENST00000397501.1
ENST00000338238.4
ENST00000544172.1
PTK2B


protein tyrosine kinase 2 beta


chr12_+_72058130 0.215 ENST00000547843.1
THAP2
THAP domain containing, apoptosis associated protein 2
chr6_-_32784687 0.214 ENST00000447394.1
ENST00000438763.2
HLA-DOB

major histocompatibility complex, class II, DO beta

chr6_+_43739697 0.206 ENST00000230480.6
VEGFA
vascular endothelial growth factor A
chr19_+_42301079 0.188 ENST00000596544.1
CEACAM3
carcinoembryonic antigen-related cell adhesion molecule 3
chr1_-_119682812 0.187 ENST00000537870.1
WARS2
tryptophanyl tRNA synthetase 2, mitochondrial
chr8_+_31496809 0.183 ENST00000518104.1
ENST00000519301.1
NRG1

neuregulin 1

chr12_-_54652060 0.180 ENST00000552562.1
CBX5
chromobox homolog 5
chr15_+_67420441 0.179 ENST00000558894.1
SMAD3
SMAD family member 3
chr1_+_155006300 0.172 ENST00000295542.1
ENST00000392480.1
ENST00000423025.2
ENST00000368419.2
DCST1



DC-STAMP domain containing 1



chr11_+_12766583 0.169 ENST00000361985.2
TEAD1
TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr1_+_182419261 0.166 ENST00000294854.8
ENST00000542961.1
RGSL1

regulator of G-protein signaling like 1

chr15_+_89631647 0.159 ENST00000569550.1
ENST00000565066.1
ENST00000565973.1
ABHD2


abhydrolase domain containing 2


chr12_+_57828521 0.159 ENST00000309668.2
INHBC
inhibin, beta C
chr11_+_117857063 0.158 ENST00000227752.3
ENST00000541785.1
ENST00000545409.1
IL10RA


interleukin 10 receptor, alpha


chr2_+_17721230 0.157 ENST00000457525.1
VSNL1
visinin-like 1
chr10_+_24738355 0.153 ENST00000307544.6
KIAA1217
KIAA1217
chr2_+_62900986 0.147 ENST00000405015.3
ENST00000413434.1
ENST00000426940.1
ENST00000449820.1
EHBP1



EH domain binding protein 1



chr17_+_80332153 0.147 ENST00000313135.2
UTS2R
urotensin 2 receptor
chr1_+_16083154 0.146 ENST00000375771.1
FBLIM1
filamin binding LIM protein 1
chr1_-_186649543 0.145 ENST00000367468.5
PTGS2
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
chr9_-_21228221 0.145 ENST00000413767.2
IFNA17
interferon, alpha 17
chr11_-_105010320 0.140 ENST00000532895.1
ENST00000530950.1
CARD18

caspase recruitment domain family, member 18

chr9_-_116837249 0.139 ENST00000466610.2
AMBP
alpha-1-microglobulin/bikunin precursor
chr2_-_37068530 0.138 ENST00000593798.1
AC007382.1
Uncharacterized protein
chr11_+_5617858 0.138 ENST00000380097.3
TRIM6
tripartite motif containing 6
chr11_-_2170786 0.132 ENST00000300632.5
IGF2
insulin-like growth factor 2 (somatomedin A)
chr8_+_39792474 0.129 ENST00000502986.2
IDO2
indoleamine 2,3-dioxygenase 2
chrX_-_71458802 0.129 ENST00000373657.1
ENST00000334463.3
ERCC6L

excision repair cross-complementing rodent repair deficiency, complementation group 6-like

chr12_-_53074182 0.129 ENST00000252244.3
KRT1
keratin 1
chr17_+_67410832 0.127 ENST00000590474.1
MAP2K6
mitogen-activated protein kinase kinase 6
chr2_-_136288113 0.125 ENST00000401392.1
ZRANB3
zinc finger, RAN-binding domain containing 3
chr7_+_37960163 0.123 ENST00000199448.4
ENST00000559325.1
ENST00000423717.1
EPDR1


ependymin related 1


chr9_+_706842 0.121 ENST00000382293.3
KANK1
KN motif and ankyrin repeat domains 1
chr4_+_156680153 0.120 ENST00000502959.1
ENST00000505764.1
ENST00000507146.1
ENST00000264424.8
ENST00000503520.1
GUCY1B3




guanylate cyclase 1, soluble, beta 3




chr4_+_80748619 0.120 ENST00000504263.1
PCAT4
prostate cancer associated transcript 4 (non-protein coding)
chr1_+_154300217 0.118 ENST00000368489.3
ATP8B2
ATPase, aminophospholipid transporter, class I, type 8B, member 2
chr1_+_87012753 0.117 ENST00000370563.3
CLCA4
chloride channel accessory 4
chr18_-_29264467 0.117 ENST00000383131.3
ENST00000237019.7
B4GALT6

UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6

chr6_+_72926145 0.116 ENST00000425662.2
ENST00000453976.2
RIMS1

regulating synaptic membrane exocytosis 1

chr4_+_118955500 0.114 ENST00000296499.5
NDST3
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
chr1_-_119683251 0.114 ENST00000369426.5
ENST00000235521.4
WARS2

tryptophanyl tRNA synthetase 2, mitochondrial

chr10_+_103912137 0.113 ENST00000603742.1
ENST00000488254.2
ENST00000461421.1
ENST00000476468.1
ENST00000370007.5
NOLC1




nucleolar and coiled-body phosphoprotein 1




chr1_-_21059029 0.113 ENST00000444387.2
ENST00000375031.1
ENST00000518294.1
SH2D5


SH2 domain containing 5


chr2_-_29297127 0.107 ENST00000331664.5
C2orf71
chromosome 2 open reading frame 71
chrX_+_99839799 0.106 ENST00000373031.4
TNMD
tenomodulin
chr9_-_21239978 0.104 ENST00000380222.2
IFNA14
interferon, alpha 14
chr2_+_90259593 0.104 ENST00000471857.1
IGKV1D-8
immunoglobulin kappa variable 1D-8
chr1_-_182573514 0.103 ENST00000367558.5
RGS16
regulator of G-protein signaling 16
chr17_-_74023291 0.102 ENST00000586740.1
EVPL
envoplakin
chr6_+_24126350 0.102 ENST00000378491.4
ENST00000378478.1
ENST00000378477.2
NRSN1


neurensin 1


chr7_+_129984630 0.101 ENST00000355388.3
ENST00000497503.1
ENST00000463587.1
ENST00000461828.1
ENST00000494311.1
ENST00000466363.2
ENST00000485477.1
ENST00000431780.2
ENST00000474905.1
CPA5








carboxypeptidase A5








chrX_-_151938171 0.101 ENST00000393902.3
ENST00000417212.1
ENST00000370278.3
MAGEA3


melanoma antigen family A, 3


chr3_-_137851220 0.101 ENST00000236709.3
A4GNT
alpha-1,4-N-acetylglucosaminyltransferase
chr19_+_50169081 0.100 ENST00000246784.3
BCL2L12
BCL2-like 12 (proline rich)
chr6_+_63921399 0.097 ENST00000356170.3
FKBP1C
FK506 binding protein 1C
chr14_-_106610852 0.096 ENST00000390603.2
IGHV3-15
immunoglobulin heavy variable 3-15
chr6_+_160542821 0.093 ENST00000366963.4
SLC22A1
solute carrier family 22 (organic cation transporter), member 1
chr15_-_35088340 0.093 ENST00000290378.4
ACTC1
actin, alpha, cardiac muscle 1
chr8_+_59323823 0.092 ENST00000399598.2
UBXN2B
UBX domain protein 2B
chr13_+_31309645 0.090 ENST00000380490.3
ALOX5AP
arachidonate 5-lipoxygenase-activating protein
chr3_-_111852128 0.090 ENST00000308910.4
GCSAM
germinal center-associated, signaling and motility
chr6_+_72922590 0.090 ENST00000523963.1
RIMS1
regulating synaptic membrane exocytosis 1
chr12_-_129308487 0.090 ENST00000266771.5
SLC15A4
solute carrier family 15 (oligopeptide transporter), member 4
chr15_-_43785274 0.089 ENST00000413546.1
TP53BP1
tumor protein p53 binding protein 1
chr19_+_50169216 0.088 ENST00000594157.1
ENST00000600947.1
ENST00000598306.1
BCL2L12


BCL2-like 12 (proline rich)


chrX_+_129535937 0.088 ENST00000305536.6
ENST00000370947.1
RBMX2

RNA binding motif protein, X-linked 2

chr4_+_156680143 0.086 ENST00000505154.1
GUCY1B3
guanylate cyclase 1, soluble, beta 3
chr4_+_71600144 0.086 ENST00000502653.1
RUFY3
RUN and FYVE domain containing 3
chr6_+_72922505 0.085 ENST00000401910.3
RIMS1
regulating synaptic membrane exocytosis 1
chr7_-_99277610 0.085 ENST00000343703.5
ENST00000222982.4
ENST00000439761.1
ENST00000339843.2
CYP3A5



cytochrome P450, family 3, subfamily A, polypeptide 5



chr8_-_66474884 0.081 ENST00000520902.1
CTD-3025N20.2
CTD-3025N20.2
chr14_-_91710852 0.080 ENST00000535815.1
ENST00000529102.1
GPR68

G protein-coupled receptor 68

chr20_-_1373682 0.080 ENST00000381724.3
FKBP1A
FK506 binding protein 1A, 12kDa
chr8_-_117043 0.080 ENST00000320901.3
OR4F21
olfactory receptor, family 4, subfamily F, member 21
chr9_-_128246769 0.080 ENST00000444226.1
MAPKAP1
mitogen-activated protein kinase associated protein 1
chr22_+_22730353 0.080 ENST00000390296.2
IGLV5-45
immunoglobulin lambda variable 5-45
chr2_-_37193606 0.079 ENST00000379213.2
ENST00000263918.4
STRN

striatin, calmodulin binding protein

chr4_+_120860695 0.077 ENST00000505122.2
RP11-700N1.1
RP11-700N1.1
chr12_-_10251603 0.076 ENST00000457018.2
CLEC1A
C-type lectin domain family 1, member A
chr1_-_222763240 0.075 ENST00000352967.4
ENST00000391882.1
ENST00000543857.1
TAF1A


TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa


chr6_+_14117872 0.075 ENST00000379153.3
CD83
CD83 molecule
chr22_+_38082330 0.073 ENST00000359114.4
NOL12
nucleolar protein 12
chr19_+_35630926 0.072 ENST00000588081.1
ENST00000589121.1
FXYD1

FXYD domain containing ion transport regulator 1

chr7_-_144533074 0.072 ENST00000360057.3
ENST00000378099.3
TPK1

thiamin pyrophosphokinase 1

chr6_+_160542870 0.072 ENST00000324965.4
ENST00000457470.2
SLC22A1

solute carrier family 22 (organic cation transporter), member 1

chr2_+_171036635 0.072 ENST00000484338.2
ENST00000334231.6
MYO3B

myosin IIIB

chr21_-_27462351 0.071 ENST00000448850.1
APP
amyloid beta (A4) precursor protein
chr1_+_197382957 0.071 ENST00000367397.1
CRB1
crumbs homolog 1 (Drosophila)
chrX_-_101410762 0.071 ENST00000543160.1
ENST00000333643.3
BEX5

brain expressed, X-linked 5

chr6_+_117198400 0.070 ENST00000332958.2
RFX6
regulatory factor X, 6
chr1_-_173176452 0.069 ENST00000281834.3
TNFSF4
tumor necrosis factor (ligand) superfamily, member 4
chr12_+_128399965 0.069 ENST00000540882.1
ENST00000542089.1
LINC00507

long intergenic non-protein coding RNA 507

chr2_+_185463093 0.069 ENST00000302277.6
ZNF804A
zinc finger protein 804A
chr2_+_90248739 0.068 ENST00000468879.1
IGKV1D-43
immunoglobulin kappa variable 1D-43
chr16_-_20367584 0.068 ENST00000570689.1
UMOD
uromodulin
chr12_+_18891045 0.067 ENST00000317658.3
CAPZA3
capping protein (actin filament) muscle Z-line, alpha 3
chr13_-_99174252 0.066 ENST00000376547.3
STK24
serine/threonine kinase 24
chr17_-_3499125 0.064 ENST00000399759.3
TRPV1
transient receptor potential cation channel, subfamily V, member 1
chr4_-_80329356 0.063 ENST00000358842.3
GK2
glycerol kinase 2
chr16_+_33006369 0.063 ENST00000425181.3
IGHV3OR16-10
immunoglobulin heavy variable 3/OR16-10 (non-functional)
chr19_+_12862604 0.062 ENST00000553030.1
BEST2
bestrophin 2
chr19_-_7812446 0.061 ENST00000394173.4
ENST00000301357.8
CD209

CD209 molecule

chr17_-_39646116 0.060 ENST00000328119.6
KRT36
keratin 36
chr9_+_27109133 0.059 ENST00000519097.1
ENST00000380036.4
TEK

TEK tyrosine kinase, endothelial

chrX_-_153141302 0.059 ENST00000361699.4
ENST00000543994.1
ENST00000370057.3
ENST00000538883.1
ENST00000361981.3
L1CAM




L1 cell adhesion molecule




chr1_-_198509804 0.059 ENST00000489986.1
ENST00000367382.1
ATP6V1G3

ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G3

chr19_+_42300548 0.058 ENST00000344550.4
CEACAM3
carcinoembryonic antigen-related cell adhesion molecule 3
chr11_+_64323156 0.058 ENST00000377585.3
SLC22A11
solute carrier family 22 (organic anion/urate transporter), member 11
chr13_-_25746416 0.057 ENST00000515384.1
ENST00000357816.2
AMER2

APC membrane recruitment protein 2

chr11_+_107461948 0.056 ENST00000265840.7
ENST00000443271.2
ELMOD1

ELMO/CED-12 domain containing 1

chr1_+_171227069 0.056 ENST00000354841.4
FMO1
flavin containing monooxygenase 1
chr18_-_29264669 0.054 ENST00000306851.5
B4GALT6
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6
chr11_-_74022658 0.054 ENST00000427714.2
ENST00000331597.4
P4HA3

prolyl 4-hydroxylase, alpha polypeptide III

chr12_-_10251576 0.053 ENST00000315330.4
CLEC1A
C-type lectin domain family 1, member A
chrY_-_20935572 0.053 ENST00000382852.1
ENST00000344884.4
ENST00000304790.3
HSFY2


heat shock transcription factor, Y linked 2


chr7_+_7606497 0.053 ENST00000340080.4
ENST00000405785.1
ENST00000433635.1
MIOS


missing oocyte, meiosis regulator, homolog (Drosophila)


chr1_-_157522180 0.053 ENST00000356953.4
ENST00000368188.2
ENST00000368190.3
ENST00000368189.3
FCRL5



Fc receptor-like 5



chr4_+_71091786 0.053 ENST00000317987.5
FDCSP
follicular dendritic cell secreted protein
chr1_-_71513471 0.053 ENST00000370931.3
ENST00000356595.4
ENST00000306666.5
ENST00000370932.2
ENST00000351052.5
ENST00000414819.1
ENST00000370924.4
PTGER3






prostaglandin E receptor 3 (subtype EP3)






chr10_-_104597286 0.052 ENST00000369887.3
CYP17A1
cytochrome P450, family 17, subfamily A, polypeptide 1
chr10_+_103911926 0.052 ENST00000605788.1
ENST00000405356.1
NOLC1

nucleolar and coiled-body phosphoprotein 1

chr1_+_367640 0.052 ENST00000426406.1
OR4F29
olfactory receptor, family 4, subfamily F, member 29
chr17_+_1933404 0.051 ENST00000263083.6
ENST00000571418.1
DPH1

diphthamide biosynthesis 1

chr8_-_124749609 0.051 ENST00000262219.6
ENST00000419625.1
ANXA13

annexin A13

chr12_-_9360966 0.051 ENST00000261336.2
PZP
pregnancy-zone protein
chr8_-_7220490 0.050 ENST00000400078.2
ZNF705G
zinc finger protein 705G
chr11_+_60609537 0.050 ENST00000227520.5
CCDC86
coiled-coil domain containing 86
chr2_-_106013400 0.049 ENST00000409807.1
FHL2
four and a half LIM domains 2
chr12_-_86650045 0.049 ENST00000604798.1
MGAT4C
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chrY_-_13524717 0.049 ENST00000331172.6
SLC9B1P1
solute carrier family 9, subfamily B (NHA1, cation proton antiporter 1), member 1 pseudogene 1
chr3_-_110612323 0.048 ENST00000383686.2
RP11-553A10.1
Uncharacterized protein
chr20_+_4152356 0.047 ENST00000379460.2
SMOX
spermine oxidase
chr13_+_27844464 0.046 ENST00000241463.4
RASL11A
RAS-like, family 11, member A
chr17_-_44657017 0.045 ENST00000573185.1
ENST00000570550.1
ENST00000445552.2
ENST00000336125.5
ENST00000329240.4
ENST00000337845.7
ARL17A





ADP-ribosylation factor-like 17A





chr22_+_27017921 0.045 ENST00000354760.3
CRYBA4
crystallin, beta A4
chr11_-_47870091 0.045 ENST00000526870.1
NUP160
nucleoporin 160kDa
chr7_+_123295861 0.044 ENST00000458573.2
ENST00000456238.2
LMOD2

leiomodin 2 (cardiac)

chr4_+_123747834 0.044 ENST00000264498.3
FGF2
fibroblast growth factor 2 (basic)
chr4_-_145061788 0.042 ENST00000512064.1
ENST00000512789.1
ENST00000504786.1
ENST00000503627.1
ENST00000535709.1
ENST00000324022.10
ENST00000360771.4
ENST00000283126.7
GYPA






GYPB
glycophorin A (MNS blood group)






glycophorin B (MNS blood group)
chr8_-_101117847 0.042 ENST00000523287.1
ENST00000519092.1
RGS22

regulator of G-protein signaling 22

chrY_+_20708557 0.041 ENST00000307393.2
ENST00000309834.4
ENST00000382856.2
HSFY1


heat shock transcription factor, Y-linked 1


chr7_+_150413645 0.040 ENST00000307194.5
GIMAP1
GTPase, IMAP family member 1
chr4_-_152682129 0.040 ENST00000512306.1
ENST00000508611.1
ENST00000515812.1
ENST00000263985.6
PET112



PET112 homolog (yeast)



chr4_+_154073469 0.039 ENST00000441616.1
TRIM2
tripartite motif containing 2
chr11_-_47870019 0.039 ENST00000378460.2
NUP160
nucleoporin 160kDa
chr19_-_40228657 0.039 ENST00000221804.4
CLC
Charcot-Leyden crystal galectin
chr11_+_60223312 0.038 ENST00000532491.1
ENST00000532073.1
ENST00000534668.1
ENST00000528313.1
ENST00000533306.1
MS4A1




membrane-spanning 4-domains, subfamily A, member 1




chr13_-_103426112 0.038 ENST00000376032.4
ENST00000376029.3
TEX30

testis expressed 30

chr11_-_47869865 0.038 ENST00000530326.1
ENST00000532747.1
NUP160

nucleoporin 160kDa

chr2_+_219524473 0.038 ENST00000439945.1
ENST00000431802.1
BCS1L

BC1 (ubiquinol-cytochrome c reductase) synthesis-like

chr14_-_107114267 0.036 ENST00000454421.2
IGHV3-64
immunoglobulin heavy variable 3-64
chr14_+_22458631 0.036 ENST00000390444.1
TRAV16
T cell receptor alpha variable 16
chr3_-_110612059 0.035 ENST00000485473.1
RP11-553A10.1
Uncharacterized protein
chrX_+_23925918 0.035 ENST00000379211.3
CXorf58
chromosome X open reading frame 58
chr2_+_90198535 0.035 ENST00000390276.2
IGKV1D-12
immunoglobulin kappa variable 1D-12
chr6_+_30130969 0.035 ENST00000376694.4
TRIM15
tripartite motif containing 15
chr3_-_49158218 0.035 ENST00000417901.1
ENST00000306026.5
ENST00000434032.2
USP19


ubiquitin specific peptidase 19


chr12_-_56236690 0.035 ENST00000322569.4
MMP19
matrix metallopeptidase 19
chr8_-_7243080 0.035 ENST00000400156.4
ZNF705G
zinc finger protein 705G
chr19_-_50168962 0.034 ENST00000599223.1
ENST00000593922.1
ENST00000600022.1
ENST00000596765.1
ENST00000599144.1
ENST00000596822.1
ENST00000598108.1
ENST00000601373.1
ENST00000595034.1
ENST00000601291.1
IRF3









interferon regulatory factor 3









chr16_-_18911366 0.034 ENST00000565224.1
SMG1
SMG1 phosphatidylinositol 3-kinase-related kinase
chr12_-_11287243 0.033 ENST00000539585.1
TAS2R30
taste receptor, type 2, member 30
chr4_-_89951028 0.033 ENST00000506913.1
FAM13A
family with sequence similarity 13, member A
chr7_-_56160625 0.033 ENST00000446428.1
ENST00000432123.1
ENST00000452681.2
ENST00000537360.1
PHKG1



phosphorylase kinase, gamma 1 (muscle)



chrX_+_151867214 0.032 ENST00000329342.5
ENST00000412733.1
ENST00000457643.1
MAGEA6


melanoma antigen family A, 6


chr19_-_50169064 0.032 ENST00000593337.1
ENST00000598808.1
ENST00000600453.1
ENST00000593818.1
ENST00000597198.1
ENST00000601809.1
ENST00000377139.3
IRF3






interferon regulatory factor 3






chr10_-_126694575 0.032 ENST00000334808.6
CTBP2
C-terminal binding protein 2
chr1_+_159409512 0.032 ENST00000423932.3
OR10J1
olfactory receptor, family 10, subfamily J, member 1
chrX_+_151903207 0.032 ENST00000370287.3
CSAG1
chondrosarcoma associated gene 1
chr17_-_44439084 0.032 ENST00000575960.1
ENST00000575698.1
ENST00000571246.1
ENST00000434041.2
ENST00000570618.1
ENST00000450673.3
ARL17B





ADP-ribosylation factor-like 17B





chr16_+_57496299 0.031 ENST00000219252.5
POLR2C
polymerase (RNA) II (DNA directed) polypeptide C, 33kDa
chr13_-_95131923 0.031 ENST00000377028.5
ENST00000446125.1
DCT

dopachrome tautomerase

chr4_+_36283213 0.031 ENST00000357504.3
DTHD1
death domain containing 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0042700 luteinizing hormone signaling pathway(GO:0042700)
0.1 0.7 GO:0002803 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.1 0.2 GO:0002644 negative regulation of tolerance induction(GO:0002644) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.1 0.3 GO:0070981 L-asparagine biosynthetic process(GO:0070981) L-asparagine metabolic process(GO:0070982)
0.1 0.2 GO:0010752 regulation of cGMP-mediated signaling(GO:0010752)
0.1 0.2 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.1 0.2 GO:1903570 regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.1 0.3 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.0 0.1 GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.0 0.1 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.0 0.3 GO:0010193 response to ozone(GO:0010193)
0.0 0.3 GO:0035803 egg coat formation(GO:0035803)
0.0 0.3 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.0 0.1 GO:0072709 cellular response to sorbitol(GO:0072709)
0.0 0.3 GO:1903575 cornified envelope assembly(GO:1903575)
0.0 0.1 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.0 0.2 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.0 0.1 GO:0036292 DNA rewinding(GO:0036292)
0.0 0.1 GO:0035990 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.0 0.2 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.0 0.2 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.0 0.2 GO:0048241 epinephrine transport(GO:0048241)
0.0 0.1 GO:2000523 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.0 0.2 GO:2000252 negative regulation of feeding behavior(GO:2000252)
0.0 0.1 GO:0050960 detection of temperature stimulus involved in thermoception(GO:0050960) response to capsazepine(GO:1901594)
0.0 0.1 GO:0009822 alkaloid catabolic process(GO:0009822)
0.0 0.1 GO:0046167 glycerol-3-phosphate biosynthetic process(GO:0046167)
0.0 0.3 GO:0045625 regulation of T-helper 1 cell differentiation(GO:0045625)
0.0 0.1 GO:0007500 mesodermal cell fate determination(GO:0007500) negative regulation of intracellular transport of viral material(GO:1901253)
0.0 0.1 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
0.0 0.1 GO:0090131 mesenchyme migration(GO:0090131)
0.0 0.3 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.2 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.1 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.0 2.0 GO:0070268 cornification(GO:0070268)
0.0 0.1 GO:0071874 cellular response to norepinephrine stimulus(GO:0071874)
0.0 0.1 GO:0072233 thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233)
0.0 0.1 GO:0046968 peptide antigen transport(GO:0046968)
0.0 0.0 GO:0032641 lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109)
0.0 0.1 GO:2000402 negative regulation of lymphocyte migration(GO:2000402)
0.0 0.2 GO:2000773 negative regulation of cellular senescence(GO:2000773)
0.0 0.1 GO:0010993 regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994)
0.0 0.1 GO:0010734 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
0.0 0.1 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.0 0.1 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.1 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 0.2 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.4 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.1 GO:0033623 regulation of integrin activation(GO:0033623)
0.0 0.1 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.0 0.1 GO:2001300 lipoxin metabolic process(GO:2001300)
0.0 0.1 GO:0006857 oligopeptide transport(GO:0006857)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0097209 epidermal lamellar body(GO:0097209)
0.0 0.2 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.0 0.2 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.1 GO:0042643 actomyosin, actin portion(GO:0042643)
0.0 0.1 GO:1990425 ryanodine receptor complex(GO:1990425)
0.0 0.2 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.1 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.2 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.7 GO:0001533 cornified envelope(GO:0001533)
0.0 0.2 GO:0042613 MHC class II protein complex(GO:0042613)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.1 0.3 GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066)
0.1 0.3 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.1 0.2 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.0 0.1 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
0.0 0.2 GO:0008513 acetylcholine transmembrane transporter activity(GO:0005277) secondary active organic cation transmembrane transporter activity(GO:0008513) acetate ester transmembrane transporter activity(GO:1901375)
0.0 0.1 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.0 0.2 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.0 0.1 GO:0019862 IgA binding(GO:0019862)
0.0 0.2 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.1 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.0 0.1 GO:0000384 first spliceosomal transesterification activity(GO:0000384)
0.0 0.3 GO:0032190 acrosin binding(GO:0032190)
0.0 0.1 GO:0022897 peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.0 0.1 GO:0004370 glycerol kinase activity(GO:0004370)
0.0 0.1 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.2 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.2 GO:0004920 interleukin-10 receptor activity(GO:0004920)
0.0 0.2 GO:0089720 caspase binding(GO:0089720)
0.0 0.0 GO:0052894 norspermine:oxygen oxidoreductase activity(GO:0052894) N1-acetylspermine:oxygen oxidoreductase (N1-acetylspermidine-forming) activity(GO:0052895)
0.0 0.2 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.2 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 0.2 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.2 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 0.2 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.1 GO:0036310 annealing helicase activity(GO:0036310)
0.0 0.1 GO:0061649 ubiquitinated histone binding(GO:0061649)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.0 0.2 PID_VEGF_VEGFR_PATHWAY VEGF and VEGFR signaling network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME_DOPAMINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.0 0.6 REACTOME_SHC1_EVENTS_IN_ERBB4_SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.4 REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.2 REACTOME_XENOBIOTICS Genes involved in Xenobiotics
0.0 0.2 REACTOME_ABACAVIR_TRANSPORT_AND_METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.2 REACTOME_CD28_DEPENDENT_VAV1_PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.2 REACTOME_GLYCOPROTEIN_HORMONES Genes involved in Glycoprotein hormones
0.0 0.3 REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.3 REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation