Motif ID: POU3F2

Z-value: 1.523


Transcription factors associated with POU3F2:

Gene SymbolEntrez IDGene Name
POU3F2 ENSG00000184486.7 POU3F2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
POU3F2hg19_v2_chr6_+_99282570_99282591-0.664.7e-04Click!


Activity profile for motif POU3F2.

activity profile for motif POU3F2


Sorted Z-values histogram for motif POU3F2

Sorted Z-values for motif POU3F2



Network of associatons between targets according to the STRING database.



First level regulatory network of POU3F2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_+_63638339 8.701 ENST00000343837.3
ENST00000469440.1
 SNTN

sentan, cilia apical structure protein

chr2_+_228735763 8.347 ENST00000373666.2
 DAW1
dynein assembly factor with WDR repeat domains 1
chr3_-_19975665 7.835 ENST00000295824.9
ENST00000389256.4
 EFHB

EF-hand domain family, member B

chr13_+_43355732 7.694 ENST00000313851.1
 FAM216B
family with sequence similarity 216, member B
chr3_-_197686847 6.596 ENST00000265239.6
 IQCG
IQ motif containing G
chr4_-_16077741 5.662 ENST00000447510.2
ENST00000540805.1
ENST00000539194.1
 PROM1


prominin 1


chr9_+_124922171 5.492 ENST00000373764.3
ENST00000536616.1
 MORN5

MORN repeat containing 5

chr7_-_16921601 5.357 ENST00000402239.3
ENST00000310398.2
ENST00000414935.1
 AGR3


anterior gradient 3


chr12_-_71551868 5.245 ENST00000247829.3
 TSPAN8
tetraspanin 8
chr1_+_111888890 5.106 ENST00000369738.4
 PIFO
primary cilia formation
chr12_-_71551652 5.033 ENST00000546561.1
 TSPAN8
tetraspanin 8
chr6_-_32557610 4.960 ENST00000360004.5
 HLA-DRB1
major histocompatibility complex, class II, DR beta 1
chr11_+_61976137 4.884 ENST00000244930.4
 SCGB2A1
secretoglobin, family 2A, member 1
chr5_-_110062349 4.665 ENST00000511883.2
ENST00000455884.2
 TMEM232

transmembrane protein 232

chr5_-_110062384 4.349 ENST00000429839.2
 TMEM232
transmembrane protein 232
chr10_+_22634384 4.304 ENST00000376624.3
ENST00000376603.2
ENST00000376601.1
ENST00000538630.1
ENST00000456231.2
ENST00000313311.6
ENST00000435326.1
 SPAG6






sperm associated antigen 6






chr4_-_100356551 4.295 ENST00000209665.4
 ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr5_-_35938674 4.291 ENST00000397366.1
ENST00000513623.1
ENST00000514524.1
ENST00000397367.2
 CAPSL



calcyphosine-like



chr11_+_111385497 4.119 ENST00000375618.4
ENST00000529167.1
ENST00000332814.6
 C11orf88


chromosome 11 open reading frame 88


chr19_-_55677920 4.049 ENST00000524407.2
ENST00000526003.1
ENST00000534170.1
 DNAAF3


dynein, axonemal, assembly factor 3



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 449 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.8 27.0 GO:0070286 axonemal dynein complex assembly(GO:0070286)
0.2 14.4 GO:0016266 O-glycan processing(GO:0016266)
3.5 10.5 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.1 10.0 GO:0060333 interferon-gamma-mediated signaling pathway(GO:0060333)
0.9 9.3 GO:0007288 sperm axoneme assembly(GO:0007288)
0.1 8.9 GO:0007368 determination of left/right symmetry(GO:0007368)
0.4 6.8 GO:0042737 drug catabolic process(GO:0042737)
1.4 5.7 GO:2000768 glomerular parietal epithelial cell differentiation(GO:0072139) positive regulation of nephron tubule epithelial cell differentiation(GO:2000768)
0.8 5.7 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
1.1 5.6 GO:0006203 dGTP catabolic process(GO:0006203)
0.1 5.5 GO:0042073 intraciliary transport(GO:0042073)
0.3 5.4 GO:0019373 epoxygenase P450 pathway(GO:0019373)
1.7 5.1 GO:0006174 dADP phosphorylation(GO:0006174) dGDP phosphorylation(GO:0006186) AMP phosphorylation(GO:0006756) CDP phosphorylation(GO:0061508) dAMP phosphorylation(GO:0061565) CMP phosphorylation(GO:0061566) dCMP phosphorylation(GO:0061567) GDP phosphorylation(GO:0061568) UDP phosphorylation(GO:0061569) dCDP phosphorylation(GO:0061570) TDP phosphorylation(GO:0061571)
1.0 5.0 GO:0002399 MHC class II protein complex assembly(GO:0002399)
0.3 4.9 GO:0070986 left/right axis specification(GO:0070986)
0.5 4.7 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.4 4.6 GO:0046600 negative regulation of centriole replication(GO:0046600)
1.5 4.4 GO:0032203 telomere formation via telomerase(GO:0032203)
1.1 4.3 GO:0001970 positive regulation of activation of membrane attack complex(GO:0001970)
0.2 4.3 GO:0010248 establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 170 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 23.8 GO:0097014 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.8 15.9 GO:0042613 MHC class II protein complex(GO:0042613)
1.8 12.6 GO:0002177 manchette(GO:0002177)
0.0 11.8 GO:0005929 cilium(GO:0005929)
0.1 10.2 GO:0005796 Golgi lumen(GO:0005796)
0.1 10.0 GO:0036064 ciliary basal body(GO:0036064)
0.1 9.6 GO:0005814 centriole(GO:0005814)
0.4 6.9 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.3 5.8 GO:0030992 intraciliary transport particle B(GO:0030992)
0.1 5.0 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.2 4.4 GO:0036038 MKS complex(GO:0036038)
0.0 3.9 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
1.0 3.8 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.7 3.6 GO:0005879 axonemal microtubule(GO:0005879)
0.1 3.3 GO:0031083 BLOC-1 complex(GO:0031083)
0.1 3.0 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 3.0 GO:0005874 microtubule(GO:0005874)
0.0 2.9 GO:0035580 specific granule lumen(GO:0035580)
0.0 2.9 GO:0005813 centrosome(GO:0005813)
0.2 2.7 GO:0036157 outer dynein arm(GO:0036157)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 281 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.6 10.5 GO:0004031 aldehyde oxidase activity(GO:0004031)
0.4 9.8 GO:0070330 aromatase activity(GO:0070330)
0.3 9.3 GO:0042605 peptide antigen binding(GO:0042605)
0.2 9.3 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 9.3 GO:0042805 actinin binding(GO:0042805)
0.1 8.0 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 6.6 GO:0005178 integrin binding(GO:0005178)
0.4 6.2 GO:0032395 MHC class II receptor activity(GO:0032395)
0.7 5.8 GO:0032554 purine deoxyribonucleotide binding(GO:0032554)
1.4 5.7 GO:1904493 Ac-Asp-Glu binding(GO:1904492) tetrahydrofolyl-poly(glutamate) polymer binding(GO:1904493)
0.7 5.7 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.2 5.7 GO:0002162 dystroglycan binding(GO:0002162)
0.5 5.1 GO:0050145 nucleoside phosphate kinase activity(GO:0050145)
0.8 4.6 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.1 4.2 GO:0070034 telomerase RNA binding(GO:0070034)
0.1 4.0 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
1.0 3.8 GO:0008900 hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.1 3.7 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
1.2 3.6 GO:0031862 prostanoid receptor binding(GO:0031862)
0.7 3.6 GO:0035529 NADH pyrophosphatase activity(GO:0035529)

Gene overrepresentation in C2:CP category:

Showing 1 to 20 of 33 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 5.6 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 3.7 PID_BETA_CATENIN_NUC_PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 2.9 PID_BMP_PATHWAY BMP receptor signaling
0.0 2.7 PID_CXCR4_PATHWAY CXCR4-mediated signaling events
0.1 2.6 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events
0.0 2.6 PID_ECADHERIN_NASCENT_AJ_PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 2.3 PID_MYC_PATHWAY C-MYC pathway
0.0 2.2 PID_ARF6_TRAFFICKING_PATHWAY Arf6 trafficking events
0.0 2.1 WNT_SIGNALING Genes related to Wnt-mediated signal transduction
0.0 1.7 ST_GRANULE_CELL_SURVIVAL_PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 1.7 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.1 1.6 PID_IL5_PATHWAY IL5-mediated signaling events
0.1 1.5 PID_CONE_PATHWAY Visual signal transduction: Cones
0.0 1.5 PID_HEDGEHOG_GLI_PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 1.3 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.3 PID_ARF6_PATHWAY Arf6 signaling events
0.0 1.2 PID_BARD1_PATHWAY BARD1 signaling events
0.0 1.2 PID_ERA_GENOMIC_PATHWAY Validated nuclear estrogen receptor alpha network
0.1 1.1 PID_P38_GAMMA_DELTA_PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 1.1 PID_NOTCH_PATHWAY Notch signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 73 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 13.7 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.6 12.8 REACTOME_TRANSLOCATION_OF_ZAP_70_TO_IMMUNOLOGICAL_SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.9 12.4 REACTOME_ETHANOL_OXIDATION Genes involved in Ethanol oxidation
0.4 7.7 REACTOME_XENOBIOTICS Genes involved in Xenobiotics
0.1 5.8 REACTOME_EXTENSION_OF_TELOMERES Genes involved in Extension of Telomeres
0.0 4.4 REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 4.3 REACTOME_PHASE1_FUNCTIONALIZATION_OF_COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 4.1 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.1 4.0 REACTOME_NETRIN1_SIGNALING Genes involved in Netrin-1 signaling
0.1 3.8 REACTOME_COMPLEMENT_CASCADE Genes involved in Complement cascade
0.4 3.5 REACTOME_DIGESTION_OF_DIETARY_CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.1 3.2 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.1 2.3 REACTOME_CHONDROITIN_SULFATE_BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.1 2.3 REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 2.2 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 2.1 REACTOME_TRANSPORT_OF_ORGANIC_ANIONS Genes involved in Transport of organic anions
0.1 1.8 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
0.0 1.8 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport
0.1 1.7 REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1 1.7 REACTOME_INTERFERON_SIGNALING Genes involved in Interferon Signaling