Motif ID: POU4F2

Z-value: 0.438


Transcription factors associated with POU4F2:

Gene SymbolEntrez IDGene Name
POU4F2 ENSG00000151615.3 POU4F2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
POU4F2hg19_v2_chr4_+_147560042_147560046-0.262.2e-01Click!


Activity profile for motif POU4F2.

activity profile for motif POU4F2


Sorted Z-values histogram for motif POU4F2

Sorted Z-values for motif POU4F2



Network of associatons between targets according to the STRING database.



First level regulatory network of POU4F2

PNG image of the network

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Top targets:


Showing 1 to 20 of 110 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_+_154393260 0.709 ENST00000435029.4
 KIF4B
kinesin family member 4B
chr21_-_31859755 0.656 ENST00000334055.3
 KRTAP19-2
keratin associated protein 19-2
chr1_-_182641367 0.651 ENST00000508450.1
 RGS8
regulator of G-protein signaling 8
chr12_-_89746173 0.650 ENST00000308385.6
 DUSP6
dual specificity phosphatase 6
chr4_+_169013666 0.598 ENST00000359299.3
 ANXA10
annexin A10
chr11_-_107729887 0.440 ENST00000525815.1
 SLC35F2
solute carrier family 35, member F2
chr4_-_47983519 0.438 ENST00000358519.4
ENST00000544810.1
ENST00000402813.3
 CNGA1


cyclic nucleotide gated channel alpha 1


chr13_-_36050819 0.414 ENST00000379919.4
 MAB21L1
mab-21-like 1 (C. elegans)
chr3_+_121774202 0.387 ENST00000469710.1
ENST00000493101.1
ENST00000330540.2
ENST00000264468.5
 CD86



CD86 molecule



chr4_+_159443090 0.383 ENST00000343542.5
ENST00000470033.1
 RXFP1

relaxin/insulin-like family peptide receptor 1

chr3_+_63428752 0.368 ENST00000295894.5
 SYNPR
synaptoporin
chr7_-_25268104 0.361 ENST00000222674.2
 NPVF
neuropeptide VF precursor
chr21_-_31864275 0.357 ENST00000334063.4
 KRTAP19-3
keratin associated protein 19-3
chr11_+_118175132 0.335 ENST00000361763.4
 CD3E
CD3e molecule, epsilon (CD3-TCR complex)
chr6_-_109777128 0.328 ENST00000358807.3
ENST00000358577.3
 MICAL1

microtubule associated monooxygenase, calponin and LIM domain containing 1

chr9_+_125133315 0.319 ENST00000223423.4
ENST00000362012.2
 PTGS1

prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)

chr8_-_49833978 0.298 ENST00000020945.1
 SNAI2
snail family zinc finger 2
chr21_-_32185570 0.294 ENST00000329621.4
 KRTAP8-1
keratin associated protein 8-1
chr14_+_42077552 0.277 ENST00000554120.1
 LRFN5
leucine rich repeat and fibronectin type III domain containing 5
chr8_-_49834299 0.274 ENST00000396822.1
 SNAI2
snail family zinc finger 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 19 of 19 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.8 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.2 0.7 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.0 0.7 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.0 0.7 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.2 0.6 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.0 0.5 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.1 0.4 GO:0002644 negative regulation of tolerance induction(GO:0002644) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.0 0.4 GO:0032277 negative regulation of gonadotropin secretion(GO:0032277)
0.0 0.4 GO:0003334 keratinocyte development(GO:0003334)
0.1 0.3 GO:0019417 sulfur oxidation(GO:0019417)
0.1 0.3 GO:0002669 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.0 0.3 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.2 GO:0006543 glutamine catabolic process(GO:0006543)
0.0 0.2 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.2 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.0 0.2 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.1 GO:0006114 glycerol biosynthetic process(GO:0006114)
0.0 0.1 GO:0016056 rhodopsin mediated signaling pathway(GO:0016056)
0.0 0.0 GO:1901876 regulation of the force of heart contraction by cardiac conduction(GO:0086092) regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877) regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081)

Gene overrepresentation in cellular_component category:

Showing 1 to 7 of 7 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.8 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.7 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.4 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.4 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.3 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.1 GO:0016013 syntrophin complex(GO:0016013)
0.0 0.1 GO:0033588 Elongator holoenzyme complex(GO:0033588)

Gene overrepresentation in molecular_function category:

Showing 1 to 13 of 13 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.7 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.7 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 0.5 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.0 0.4 GO:0043855 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.4 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.3 GO:0042608 T cell receptor binding(GO:0042608)
0.0 0.3 GO:0030553 cGMP binding(GO:0030553)
0.0 0.3 GO:0071949 FAD binding(GO:0071949)
0.0 0.2 GO:0004359 glutaminase activity(GO:0004359)
0.0 0.2 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.0 0.1 GO:0004613 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.0 0.1 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.1 GO:0060230 lipoprotein lipase activator activity(GO:0060230)

Gene overrepresentation in C2:CP category:

Showing 1 to 4 of 4 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.8 PID_KIT_PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.7 PID_RHODOPSIN_PATHWAY Visual signal transduction: Rods
0.0 0.7 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4
0.0 0.7 ST_ERK1_ERK2_MAPK_PATHWAY ERK1/ERK2 MAPK Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 4 of 4 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.7 REACTOME_ERKS_ARE_INACTIVATED Genes involved in ERKs are inactivated
0.0 0.7 REACTOME_KINESINS Genes involved in Kinesins
0.0 0.4 REACTOME_CD28_DEPENDENT_VAV1_PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.3 REACTOME_TRANSLOCATION_OF_ZAP_70_TO_IMMUNOLOGICAL_SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse