Motif ID: POU6F1

Z-value: 0.428


Transcription factors associated with POU6F1:

Gene SymbolEntrez IDGene Name
POU6F1 ENSG00000184271.11 POU6F1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
POU6F1hg19_v2_chr12_-_51611477_516116120.048.4e-01Click!


Activity profile for motif POU6F1.

activity profile for motif POU6F1


Sorted Z-values histogram for motif POU6F1

Sorted Z-values for motif POU6F1



Network of associatons between targets according to the STRING database.



First level regulatory network of POU6F1

PNG image of the network

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Top targets:


Showing 1 to 20 of 112 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_+_151646800 1.214 ENST00000354675.6
 AKAP12
A kinase (PRKA) anchor protein 12
chr1_-_153123345 0.799 ENST00000368748.4
 SPRR2G
small proline-rich protein 2G
chr1_-_197115818 0.553 ENST00000367409.4
ENST00000294732.7
 ASPM

asp (abnormal spindle) homolog, microcephaly associated (Drosophila)

chr2_+_128403720 0.519 ENST00000272644.3
 GPR17
G protein-coupled receptor 17
chr2_+_128403439 0.514 ENST00000544369.1
 GPR17
G protein-coupled receptor 17
chr8_+_39792474 0.498 ENST00000502986.2
 IDO2
indoleamine 2,3-dioxygenase 2
chr12_-_30887948 0.484 ENST00000433722.2
 CAPRIN2
caprin family member 2
chr9_+_128509624 0.483 ENST00000342287.5
ENST00000373487.4
 PBX3

pre-B-cell leukemia homeobox 3

chr8_+_118147498 0.472 ENST00000519688.1
ENST00000456015.2
 SLC30A8

solute carrier family 30 (zinc transporter), member 8

chr6_-_110501200 0.455 ENST00000392586.1
ENST00000419252.1
ENST00000392589.1
ENST00000392588.1
ENST00000359451.2
 WASF1




WAS protein family, member 1




chr6_+_29274403 0.451 ENST00000377160.2
 OR14J1
olfactory receptor, family 14, subfamily J, member 1
chr2_+_191045656 0.450 ENST00000443551.2
 C2orf88
chromosome 2 open reading frame 88
chr13_+_107029084 0.425 ENST00000444865.1
 LINC00460
long intergenic non-protein coding RNA 460
chr2_+_191045562 0.409 ENST00000340623.4
 C2orf88
chromosome 2 open reading frame 88
chr7_-_83824169 0.396 ENST00000265362.4
 SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr2_+_115219171 0.352 ENST00000409163.1
 DPP10
dipeptidyl-peptidase 10 (non-functional)
chr20_-_50419055 0.338 ENST00000217086.4
 SALL4
spalt-like transcription factor 4
chr12_+_102514019 0.327 ENST00000537257.1
ENST00000358383.5
ENST00000392911.2
 PARPBP


PARP1 binding protein


chr12_+_15699286 0.312 ENST00000442921.2
ENST00000542557.1
ENST00000445537.2
ENST00000544244.1
 PTPRO



protein tyrosine phosphatase, receptor type, O



chr3_+_46395219 0.299 ENST00000445132.2
ENST00000292301.4
 CCR2

chemokine (C-C motif) receptor 2


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 29 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.2 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.1 1.0 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.2 0.6 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.0 0.6 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.1 0.5 GO:0007386 compartment pattern specification(GO:0007386)
0.0 0.5 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 0.5 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0 0.5 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.0 0.5 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.1 0.4 GO:0048880 sensory system development(GO:0048880)
0.0 0.4 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.1 0.3 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.1 0.3 GO:1902567 negative regulation of eosinophil activation(GO:1902567) positive regulation of monocyte extravasation(GO:2000439)
0.0 0.3 GO:2000574 regulation of microtubule motor activity(GO:2000574)
0.1 0.2 GO:0015817 histidine transport(GO:0015817) L-histidine transmembrane transport(GO:0089709) L-histidine transport(GO:1902024)
0.0 0.2 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.0 0.1 GO:0090086 negative regulation of protein deubiquitination(GO:0090086)
0.0 0.1 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.0 0.1 GO:0098907 protein localization to M-band(GO:0036309) regulation of SA node cell action potential(GO:0098907)
0.0 0.1 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)

Gene overrepresentation in cellular_component category:

Showing 1 to 8 of 8 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.8 GO:0001533 cornified envelope(GO:0001533)
0.1 0.6 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.5 GO:0031209 SCAR complex(GO:0031209)
0.0 0.3 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.3 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.2 GO:0072588 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.0 0.2 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 0.1 GO:0071001 U4/U6 snRNP(GO:0071001)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 20 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.2 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 1.0 GO:0001637 G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.0 0.9 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.2 0.5 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
0.0 0.5 GO:0005549 odorant binding(GO:0005549)
0.0 0.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.4 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.4 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.1 0.3 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.0 0.3 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.3 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.3 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.2 GO:1901474 azole transmembrane transporter activity(GO:1901474)
0.0 0.2 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.2 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.0 0.1 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.0 0.1 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.1 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.1 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 4 of 4 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.0 REACTOME_P2Y_RECEPTORS Genes involved in P2Y receptors
0.0 0.7 REACTOME_TRYPTOPHAN_CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.5 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.0 0.4 REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion