Motif ID: POU6F2
Z-value: 0.652
Transcription factors associated with POU6F2:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| POU6F2 | ENSG00000106536.15 | POU6F2 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| POU6F2 | hg19_v2_chr7_+_39017504_39017598, hg19_v2_chr7_+_39125365_39125489 | 0.09 | 6.7e-01 | Click! |
Top targets:
Showing 1 to 20 of 165 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 47 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 3.0 | GO:0002862 | negative regulation of inflammatory response to antigenic stimulus(GO:0002862) |
| 0.3 | 1.6 | GO:1902261 | positive regulation of delayed rectifier potassium channel activity(GO:1902261) |
| 0.1 | 1.6 | GO:0010739 | positive regulation of protein kinase A signaling(GO:0010739) |
| 0.0 | 1.5 | GO:0061003 | positive regulation of dendritic spine morphogenesis(GO:0061003) |
| 0.1 | 1.2 | GO:0090091 | positive regulation of extracellular matrix disassembly(GO:0090091) |
| 0.1 | 1.1 | GO:0046602 | regulation of mitotic centrosome separation(GO:0046602) |
| 0.2 | 1.0 | GO:0051541 | elastin metabolic process(GO:0051541) |
| 0.0 | 1.0 | GO:0060159 | regulation of dopamine receptor signaling pathway(GO:0060159) |
| 0.1 | 0.9 | GO:0048251 | elastic fiber assembly(GO:0048251) |
| 0.3 | 0.8 | GO:0036058 | filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060) |
| 0.3 | 0.8 | GO:0042663 | regulation of endodermal cell fate specification(GO:0042663) |
| 0.1 | 0.7 | GO:0060298 | positive regulation of sarcomere organization(GO:0060298) |
| 0.1 | 0.7 | GO:0021785 | branchiomotor neuron axon guidance(GO:0021785) |
| 0.0 | 0.7 | GO:0021670 | lateral ventricle development(GO:0021670) |
| 0.1 | 0.6 | GO:0035627 | ceramide transport(GO:0035627) |
| 0.1 | 0.6 | GO:0007217 | tachykinin receptor signaling pathway(GO:0007217) |
| 0.0 | 0.6 | GO:1903504 | regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504) |
| 0.2 | 0.5 | GO:1904580 | regulation of intracellular mRNA localization(GO:1904580) positive regulation of intracellular mRNA localization(GO:1904582) |
| 0.1 | 0.5 | GO:0048880 | sensory system development(GO:0048880) |
| 0.0 | 0.5 | GO:0009954 | proximal/distal pattern formation(GO:0009954) |
Gene overrepresentation in cellular_component category:
Showing 1 to 17 of 17 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.6 | GO:0014701 | junctional sarcoplasmic reticulum membrane(GO:0014701) |
| 0.1 | 1.2 | GO:0005828 | kinetochore microtubule(GO:0005828) |
| 0.0 | 1.0 | GO:0044298 | neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298) |
| 0.0 | 1.0 | GO:0005876 | spindle microtubule(GO:0005876) |
| 0.0 | 1.0 | GO:0030669 | clathrin-coated endocytic vesicle membrane(GO:0030669) |
| 0.1 | 0.9 | GO:0071953 | elastic fiber(GO:0071953) |
| 0.0 | 0.8 | GO:0031597 | cytosolic proteasome complex(GO:0031597) |
| 0.0 | 0.7 | GO:0002116 | semaphorin receptor complex(GO:0002116) |
| 0.0 | 0.7 | GO:0001533 | cornified envelope(GO:0001533) |
| 0.1 | 0.6 | GO:0097209 | epidermal lamellar body(GO:0097209) |
| 0.0 | 0.6 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
| 0.0 | 0.3 | GO:0097504 | Gemini of coiled bodies(GO:0097504) |
| 0.0 | 0.2 | GO:0072588 | box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588) |
| 0.0 | 0.2 | GO:0033588 | Elongator holoenzyme complex(GO:0033588) |
| 0.0 | 0.2 | GO:0030123 | AP-3 adaptor complex(GO:0030123) |
| 0.0 | 0.1 | GO:0042720 | mitochondrial inner membrane peptidase complex(GO:0042720) |
| 0.0 | 0.1 | GO:0033165 | interphotoreceptor matrix(GO:0033165) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 33 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 3.3 | GO:0008179 | adenylate cyclase binding(GO:0008179) |
| 0.1 | 3.0 | GO:0001637 | G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950) |
| 0.0 | 1.1 | GO:0002162 | dystroglycan binding(GO:0002162) |
| 0.0 | 1.0 | GO:0005001 | transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198) |
| 0.0 | 1.0 | GO:0008574 | ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) |
| 0.0 | 0.9 | GO:0005154 | epidermal growth factor receptor binding(GO:0005154) |
| 0.0 | 0.8 | GO:0017017 | MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) |
| 0.1 | 0.7 | GO:0008454 | alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454) |
| 0.1 | 0.7 | GO:0031433 | telethonin binding(GO:0031433) |
| 0.0 | 0.7 | GO:0017154 | semaphorin receptor activity(GO:0017154) |
| 0.0 | 0.7 | GO:0070628 | proteasome binding(GO:0070628) |
| 0.2 | 0.6 | GO:0047696 | beta-adrenergic receptor kinase activity(GO:0047696) |
| 0.2 | 0.6 | GO:0008431 | vitamin E binding(GO:0008431) |
| 0.1 | 0.6 | GO:0034040 | lipid-transporting ATPase activity(GO:0034040) |
| 0.0 | 0.5 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
| 0.0 | 0.5 | GO:0017166 | vinculin binding(GO:0017166) |
| 0.0 | 0.5 | GO:0035925 | mRNA 3'-UTR AU-rich region binding(GO:0035925) |
| 0.1 | 0.4 | GO:0033754 | indoleamine 2,3-dioxygenase activity(GO:0033754) |
| 0.0 | 0.4 | GO:0005549 | odorant binding(GO:0005549) |
| 0.0 | 0.4 | GO:0005436 | sodium:phosphate symporter activity(GO:0005436) |
Gene overrepresentation in C2:CP category:
Showing 1 to 2 of 2 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.9 | PID_ERBB_NETWORK_PATHWAY | ErbB receptor signaling network |
| 0.0 | 0.7 | ST_ERK1_ERK2_MAPK_PATHWAY | ERK1/ERK2 MAPK Pathway |
Gene overrepresentation in C2:CP:REACTOME category:
Showing 1 to 14 of 14 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 3.0 | REACTOME_P2Y_RECEPTORS | Genes involved in P2Y receptors |
| 0.1 | 1.1 | REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION | Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion |
| 0.0 | 1.0 | REACTOME_SHC1_EVENTS_IN_ERBB4_SIGNALING | Genes involved in SHC1 events in ERBB4 signaling |
| 0.0 | 1.0 | REACTOME_KINESINS | Genes involved in Kinesins |
| 0.0 | 0.8 | REACTOME_ERKS_ARE_INACTIVATED | Genes involved in ERKs are inactivated |
| 0.0 | 0.7 | REACTOME_N_GLYCAN_ANTENNAE_ELONGATION | Genes involved in N-Glycan antennae elongation |
| 0.0 | 0.7 | REACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING | Genes involved in Downregulation of TGF-beta receptor signaling |
| 0.0 | 0.6 | REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS | Genes involved in ABCA transporters in lipid homeostasis |
| 0.0 | 0.5 | REACTOME_GLYCOPROTEIN_HORMONES | Genes involved in Glycoprotein hormones |
| 0.0 | 0.5 | REACTOME_DESTABILIZATION_OF_MRNA_BY_BRF1 | Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1) |
| 0.0 | 0.4 | REACTOME_TRYPTOPHAN_CATABOLISM | Genes involved in Tryptophan catabolism |
| 0.0 | 0.3 | REACTOME_ABACAVIR_TRANSPORT_AND_METABOLISM | Genes involved in Abacavir transport and metabolism |
| 0.0 | 0.3 | REACTOME_NOREPINEPHRINE_NEUROTRANSMITTER_RELEASE_CYCLE | Genes involved in Norepinephrine Neurotransmitter Release Cycle |
| 0.0 | 0.1 | REACTOME_INHIBITION_OF_INSULIN_SECRETION_BY_ADRENALINE_NORADRENALINE | Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline |
