Motif ID: PRDM4

Z-value: 0.196


Transcription factors associated with PRDM4:

Gene SymbolEntrez IDGene Name
PRDM4 ENSG00000110851.7 PRDM4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
PRDM4hg19_v2_chr12_-_108154925_108154945-0.331.1e-01Click!


Activity profile for motif PRDM4.

activity profile for motif PRDM4


Sorted Z-values histogram for motif PRDM4

Sorted Z-values for motif PRDM4



Network of associatons between targets according to the STRING database.



First level regulatory network of PRDM4

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr14_+_105953204 0.483 ENST00000409393.2
 CRIP1
cysteine-rich protein 1 (intestinal)
chr14_+_105953246 0.477 ENST00000392531.3
 CRIP1
cysteine-rich protein 1 (intestinal)
chr5_-_61031495 0.304 ENST00000506550.1
ENST00000512882.2
 CTD-2170G1.2

CTD-2170G1.2

chr9_-_127263265 0.191 ENST00000373587.3
 NR5A1
nuclear receptor subfamily 5, group A, member 1
chr1_+_54359854 0.164 ENST00000361921.3
ENST00000322679.6
ENST00000532493.1
ENST00000525202.1
ENST00000524406.1
ENST00000388876.3
 DIO1





deiodinase, iodothyronine, type I





chr17_+_42634844 0.116 ENST00000315323.3
 FZD2
frizzled family receptor 2
chr5_+_140261703 0.111 ENST00000409494.1
ENST00000289272.2
 PCDHA13

protocadherin alpha 13

chr19_-_35264089 0.107 ENST00000588760.1
ENST00000329285.8
ENST00000587354.2
 ZNF599


zinc finger protein 599


chr11_-_40314652 0.102 ENST00000527150.1
 LRRC4C
leucine rich repeat containing 4C
chr20_+_62697564 0.097 ENST00000458442.1
 TCEA2
transcription elongation factor A (SII), 2
chr13_+_52436111 0.097 ENST00000242819.4
 CCDC70
coiled-coil domain containing 70
chr2_+_233734994 0.090 ENST00000331342.2
 C2orf82
chromosome 2 open reading frame 82
chr17_-_9929581 0.088 ENST00000437099.2
ENST00000396115.2
 GAS7

growth arrest-specific 7

chr20_+_30555805 0.086 ENST00000562532.2
 XKR7
XK, Kell blood group complex subunit-related family, member 7
chr3_+_16926441 0.085 ENST00000418129.2
ENST00000396755.2
 PLCL2

phospholipase C-like 2

chr22_-_50050986 0.073 ENST00000405854.1
 C22orf34
chromosome 22 open reading frame 34
chr12_+_104682496 0.073 ENST00000378070.4
 TXNRD1
thioredoxin reductase 1
chr9_+_96338647 0.071 ENST00000359246.4
 PHF2
PHD finger protein 2
chr14_+_32030582 0.068 ENST00000550649.1
ENST00000281081.7
 NUBPL

nucleotide binding protein-like

chr12_-_58240470 0.067 ENST00000548823.1
ENST00000398073.2
 CTDSP2

CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2

chr11_+_47279504 0.066 ENST00000441012.2
ENST00000437276.1
ENST00000436029.1
ENST00000467728.1
ENST00000405853.3
 NR1H3




nuclear receptor subfamily 1, group H, member 3




chr1_+_172502336 0.064 ENST00000263688.3
 SUCO
SUN domain containing ossification factor
chr15_+_45315302 0.063 ENST00000267814.9
 SORD
sorbitol dehydrogenase
chr6_-_32160622 0.063 ENST00000487761.1
ENST00000375040.3
 GPSM3

G-protein signaling modulator 3

chr5_-_180688105 0.061 ENST00000327767.4
 TRIM52
tripartite motif containing 52
chr1_+_27114418 0.059 ENST00000078527.4
 PIGV
phosphatidylinositol glycan anchor biosynthesis, class V
chr20_-_61569296 0.059 ENST00000370371.4
 DIDO1
death inducer-obliterator 1
chr1_+_27114589 0.056 ENST00000431541.1
ENST00000449950.2
ENST00000374145.1
 PIGV


phosphatidylinositol glycan anchor biosynthesis, class V


chr1_+_151043070 0.055 ENST00000368918.3
ENST00000368917.1
 GABPB2

GA binding protein transcription factor, beta subunit 2

chr11_+_58910295 0.053 ENST00000420244.1
 FAM111A
family with sequence similarity 111, member A
chr6_+_26045603 0.052 ENST00000540144.1
 HIST1H3C
histone cluster 1, H3c
chr5_-_78281775 0.052 ENST00000396151.3
ENST00000565165.1
 ARSB

arylsulfatase B

chr5_-_34916871 0.051 ENST00000382038.2
 RAD1
RAD1 homolog (S. pombe)
chr19_-_49371711 0.049 ENST00000355496.5
ENST00000263265.6
 PLEKHA4

pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4

chr4_+_667686 0.046 ENST00000505477.1
 MYL5
myosin, light chain 5, regulatory
chr2_+_234296792 0.044 ENST00000409813.3
 DGKD
diacylglycerol kinase, delta 130kDa
chr11_+_8040739 0.038 ENST00000534099.1
 TUB
tubby bipartite transcription factor
chr20_-_61569227 0.038 ENST00000266070.4
ENST00000395335.2
ENST00000266071.5
 DIDO1


death inducer-obliterator 1


chr6_-_8064567 0.038 ENST00000543936.1
ENST00000397457.2
 BLOC1S5

biogenesis of lysosomal organelles complex-1, subunit 5, muted

chr11_+_19138670 0.037 ENST00000446113.2
ENST00000399351.3
 ZDHHC13

zinc finger, DHHC-type containing 13

chr14_+_24025194 0.037 ENST00000404535.3
ENST00000288014.6
 THTPA

thiamine triphosphatase

chr4_+_667307 0.036 ENST00000506838.1
 MYL5
myosin, light chain 5, regulatory
chr9_-_16727978 0.033 ENST00000418777.1
ENST00000468187.2
 BNC2

basonuclin 2

chr8_+_94712732 0.032 ENST00000518322.1
 FAM92A1
family with sequence similarity 92, member A1
chr2_-_179343226 0.032 ENST00000434643.2
 FKBP7
FK506 binding protein 7
chr5_+_102455968 0.032 ENST00000358359.3
 PPIP5K2
diphosphoinositol pentakisphosphate kinase 2
chr19_-_11639931 0.031 ENST00000592312.1
ENST00000590480.1
ENST00000585318.1
ENST00000252440.7
ENST00000417981.2
ENST00000270517.7
 ECSIT





ECSIT signalling integrator





chr22_+_38864041 0.030 ENST00000216014.4
ENST00000409006.3
 KDELR3

KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3

chr19_-_11639910 0.028 ENST00000588998.1
ENST00000586149.1
 ECSIT

ECSIT signalling integrator

chr19_+_50180317 0.028 ENST00000534465.1
 PRMT1
protein arginine methyltransferase 1
chr1_+_171750776 0.028 ENST00000458517.1
ENST00000362019.3
ENST00000367737.5
ENST00000361735.3
 METTL13



methyltransferase like 13



chr4_-_83295103 0.027 ENST00000313899.7
ENST00000352301.4
ENST00000509107.1
ENST00000353341.4
ENST00000541060.1
 HNRNPD




heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)




chr5_+_102455853 0.025 ENST00000515845.1
ENST00000321521.9
ENST00000507921.1
 PPIP5K2


diphosphoinositol pentakisphosphate kinase 2


chr19_+_41117770 0.023 ENST00000601032.1
 LTBP4
latent transforming growth factor beta binding protein 4
chr16_+_15068916 0.023 ENST00000455313.2
 PDXDC1
pyridoxal-dependent decarboxylase domain containing 1
chr2_-_179343268 0.023 ENST00000424785.2
 FKBP7
FK506 binding protein 7
chr17_+_7788104 0.022 ENST00000380358.4
 CHD3
chromodomain helicase DNA binding protein 3
chr5_-_102455801 0.022 ENST00000508629.1
ENST00000399004.2
 GIN1

gypsy retrotransposon integrase 1

chr16_+_15068955 0.017 ENST00000396410.4
ENST00000569715.1
ENST00000450288.2
 PDXDC1


pyridoxal-dependent decarboxylase domain containing 1


chr16_+_88636789 0.017 ENST00000301011.5
ENST00000452588.2
 ZC3H18

zinc finger CCCH-type containing 18

chr8_+_94712752 0.014 ENST00000522324.1
ENST00000522803.1
ENST00000423990.2
 FAM92A1


family with sequence similarity 92, member A1


chr8_+_81397846 0.012 ENST00000379091.4
 ZBTB10
zinc finger and BTB domain containing 10
chr5_+_80256453 0.006 ENST00000265080.4
 RASGRF2
Ras protein-specific guanine nucleotide-releasing factor 2
chr9_+_17135016 0.006 ENST00000425824.1
ENST00000262360.5
ENST00000380641.4
 CNTLN


centlein, centrosomal protein


chr1_+_6511651 0.005 ENST00000434576.1
 ESPN
espin
chr1_-_68516393 0.003 ENST00000395201.1
 DIRAS3
DIRAS family, GTP-binding RAS-like 3
chr7_-_23571586 0.002 ENST00000538367.1
ENST00000392502.4
ENST00000297071.4
 TRA2A


transformer 2 alpha homolog (Drosophila)


chr7_-_38398721 0.001 ENST00000390346.2
 TRGV3
T cell receptor gamma variable 3
chr7_+_90893783 0.001 ENST00000287934.2
 FZD1
frizzled family receptor 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.0 0.2 GO:0007538 primary sex determination(GO:0007538)
0.0 0.1 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.0 0.1 GO:0061188 negative regulation of chromatin silencing at rDNA(GO:0061188)
0.0 0.1 GO:0090341 negative regulation of secretion of lysosomal enzymes(GO:0090341)
0.0 0.1 GO:0006059 hexitol metabolic process(GO:0006059)
0.0 0.1 GO:0051598 meiotic recombination checkpoint(GO:0051598)
0.0 0.1 GO:0003150 muscular septum morphogenesis(GO:0003150)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0031501 mannosyltransferase complex(GO:0031501)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.2 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.1 GO:0098626 methylselenol reductase activity(GO:0098625) methylseleninic acid reductase activity(GO:0098626)
0.0 0.1 GO:0004376 glycolipid mannosyltransferase activity(GO:0004376)
0.0 0.1 GO:0032810 sterol response element binding(GO:0032810)
0.0 0.1 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)