Motif ID: RARB

Z-value: 0.374


Transcription factors associated with RARB:

Gene SymbolEntrez IDGene Name
RARB ENSG00000077092.14 RARB

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
RARBhg19_v2_chr3_+_25469724_25469773-0.528.8e-03Click!


Activity profile for motif RARB.

activity profile for motif RARB


Sorted Z-values histogram for motif RARB

Sorted Z-values for motif RARB



Network of associatons between targets according to the STRING database.



First level regulatory network of RARB

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_+_132286754 0.653 ENST00000434330.1
 CCDC74A
coiled-coil domain containing 74A
chr1_-_19186176 0.531 ENST00000375371.3
 TAS1R2
taste receptor, type 1, member 2
chr12_-_10151773 0.451 ENST00000298527.6
ENST00000348658.4
 CLEC1B

C-type lectin domain family 1, member B

chr5_-_35195338 0.449 ENST00000509839.1
 PRLR
prolactin receptor
chr2_+_132287237 0.431 ENST00000467992.2
 CCDC74A
coiled-coil domain containing 74A
chr1_-_23521222 0.418 ENST00000374619.1
 HTR1D
5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled
chr1_-_23520755 0.406 ENST00000314113.3
 HTR1D
5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled
chr17_-_62097904 0.365 ENST00000583366.1
 ICAM2
intercellular adhesion molecule 2
chr19_+_5914213 0.360 ENST00000222125.5
ENST00000452990.2
ENST00000588865.1
 CAPS


calcyphosine


chr5_+_53751445 0.345 ENST00000302005.1
 HSPB3
heat shock 27kDa protein 3
chr11_-_63381925 0.313 ENST00000415826.1
 PLA2G16
phospholipase A2, group XVI
chr6_-_150212029 0.294 ENST00000529948.1
ENST00000357183.4
ENST00000367363.3
 RAET1E


retinoic acid early transcript 1E


chr2_+_217082311 0.283 ENST00000597904.1
 RP11-566E18.3
RP11-566E18.3
chr1_-_46642154 0.267 ENST00000540385.1
 PIK3R3
phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
chr13_+_73302047 0.263 ENST00000377814.2
ENST00000377815.3
ENST00000390667.5
 BORA


bora, aurora kinase A activator


chr6_+_31638156 0.260 ENST00000409525.1
 LY6G5B
lymphocyte antigen 6 complex, locus G5B
chr6_-_150217195 0.254 ENST00000532335.1
 RAET1E
retinoic acid early transcript 1E
chr17_+_26800756 0.247 ENST00000537681.1
 SLC13A2
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
chr17_+_26800648 0.235 ENST00000545060.1
 SLC13A2
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
chr12_+_56075330 0.232 ENST00000394252.3
 METTL7B
methyltransferase like 7B

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 29 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 0.8 GO:0014827 intestine smooth muscle contraction(GO:0014827)
0.1 0.5 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.1 0.5 GO:0046485 ether lipid metabolic process(GO:0046485)
0.1 0.4 GO:0038161 prolactin signaling pathway(GO:0038161)
0.0 0.4 GO:0030220 platelet formation(GO:0030220)
0.0 0.3 GO:0009450 acetate metabolic process(GO:0006083) glutamate decarboxylation to succinate(GO:0006540) gamma-aminobutyric acid catabolic process(GO:0009450)
0.0 0.3 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.2 GO:0036378 alkaloid catabolic process(GO:0009822) calcitriol biosynthetic process from calciol(GO:0036378)
0.0 0.2 GO:1903721 regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721)
0.0 0.2 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0 0.2 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.2 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.0 0.2 GO:0036150 phosphatidylserine acyl-chain remodeling(GO:0036150)
0.0 0.1 GO:0070512 regulation of histone H4-K20 methylation(GO:0070510) positive regulation of histone H4-K20 methylation(GO:0070512)
0.0 0.1 GO:0036269 swimming behavior(GO:0036269)
0.0 0.1 GO:0060545 CD8-positive, alpha-beta cytotoxic T cell extravasation(GO:0035698) positive regulation of necroptotic process(GO:0060545) regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation(GO:2000452)
0.0 0.1 GO:0010902 positive regulation of very-low-density lipoprotein particle remodeling(GO:0010902)
0.0 0.1 GO:0006642 triglyceride mobilization(GO:0006642) response to selenium ion(GO:0010269)
0.0 0.1 GO:0006742 NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
0.0 0.1 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)

Gene overrepresentation in cellular_component category:

Showing 1 to 11 of 11 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.4 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.3 GO:0042555 MCM complex(GO:0042555)
0.0 0.3 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.2 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.0 0.2 GO:0001520 outer dense fiber(GO:0001520)
0.0 0.1 GO:0031436 BRCA1-BARD1 complex(GO:0031436)
0.0 0.1 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 0.1 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.1 GO:0033269 internode region of axon(GO:0033269)
0.0 0.1 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.0 0.0 GO:0005608 laminin-3 complex(GO:0005608)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 23 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 0.8 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.1 0.7 GO:0052739 phosphatidylserine 1-acylhydrolase activity(GO:0052739)
0.2 0.5 GO:0015361 low-affinity sodium:dicarboxylate symporter activity(GO:0015361)
0.0 0.5 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.0 0.5 GO:0008527 taste receptor activity(GO:0008527)
0.1 0.4 GO:0004925 prolactin receptor activity(GO:0004925)
0.0 0.3 GO:0035473 lipase binding(GO:0035473)
0.0 0.3 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.2 GO:0070643 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.0 0.2 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.2 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.2 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.2 GO:0019864 IgG binding(GO:0019864)
0.0 0.2 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.2 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.1 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
0.0 0.1 GO:0098626 methylselenol reductase activity(GO:0098625) methylseleninic acid reductase activity(GO:0098626)
0.0 0.1 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
0.0 0.1 GO:0017129 triglyceride binding(GO:0017129)
0.0 0.1 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 11 of 11 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.2 REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 0.8 REACTOME_SEROTONIN_RECEPTORS Genes involved in Serotonin receptors
0.0 0.5 REACTOME_ACYL_CHAIN_REMODELLING_OF_PS Genes involved in Acyl chain remodelling of PS
0.0 0.5 REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.5 REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.4 REACTOME_PROLACTIN_RECEPTOR_SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.4 REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.3 REACTOME_UNWINDING_OF_DNA Genes involved in Unwinding of DNA
0.0 0.2 REACTOME_REVERSIBLE_HYDRATION_OF_CARBON_DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.2 REACTOME_IL_7_SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.2 REACTOME_XENOBIOTICS Genes involved in Xenobiotics