Motif ID: RELB

Z-value: 0.549


Transcription factors associated with RELB:

Gene SymbolEntrez IDGene Name
RELB ENSG00000104856.9 RELB

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
RELBhg19_v2_chr19_+_45504688_455047820.001.0e+00Click!


Activity profile for motif RELB.

activity profile for motif RELB


Sorted Z-values histogram for motif RELB

Sorted Z-values for motif RELB



Network of associatons between targets according to the STRING database.



First level regulatory network of RELB

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chrX_-_73072534 0.855 ENST00000429829.1
 XIST
X inactive specific transcript (non-protein coding)
chr4_-_74864386 0.784 ENST00000296027.4
 CXCL5
chemokine (C-X-C motif) ligand 5
chr6_-_32636145 0.757 ENST00000399084.1
 HLA-DQB1
major histocompatibility complex, class II, DQ beta 1
chr7_+_76054224 0.663 ENST00000394857.3
 ZP3
zona pellucida glycoprotein 3 (sperm receptor)
chr1_-_186649543 0.635 ENST00000367468.5
 PTGS2
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
chr1_-_95392635 0.628 ENST00000538964.1
ENST00000394202.4
ENST00000370206.4
 CNN3


calponin 3, acidic


chr4_+_74702214 0.615 ENST00000226317.5
ENST00000515050.1
 CXCL6

chemokine (C-X-C motif) ligand 6

chr6_-_30080876 0.443 ENST00000376734.3
 TRIM31
tripartite motif containing 31
chr6_-_29527702 0.387 ENST00000377050.4
 UBD
ubiquitin D
chr6_+_32605195 0.368 ENST00000374949.2
 HLA-DQA1
major histocompatibility complex, class II, DQ alpha 1
chr6_+_32605134 0.355 ENST00000343139.5
ENST00000395363.1
ENST00000496318.1
 HLA-DQA1


major histocompatibility complex, class II, DQ alpha 1


chr13_+_32605437 0.332 ENST00000380250.3
 FRY
furry homolog (Drosophila)
chr3_-_156878540 0.317 ENST00000461804.1
 CCNL1
cyclin L1
chr1_+_156119466 0.301 ENST00000414683.1
 SEMA4A
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr12_+_96588279 0.297 ENST00000552142.1
 ELK3
ELK3, ETS-domain protein (SRF accessory protein 2)
chr5_+_150591678 0.297 ENST00000523466.1
 GM2A
GM2 ganglioside activator
chr9_+_33240157 0.296 ENST00000379721.3
 SPINK4
serine peptidase inhibitor, Kazal type 4
chr9_+_75263565 0.271 ENST00000396237.3
 TMC1
transmembrane channel-like 1
chr11_+_18287721 0.270 ENST00000356524.4
 SAA1
serum amyloid A1
chr11_+_18287801 0.267 ENST00000532858.1
ENST00000405158.2
 SAA1

serum amyloid A1


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 65 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.3 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.0 1.5 GO:0060333 interferon-gamma-mediated signaling pathway(GO:0060333)
0.1 0.8 GO:0019264 glycine biosynthetic process from serine(GO:0019264)
0.2 0.7 GO:2000196 positive regulation of female gonad development(GO:2000196)
0.2 0.6 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.0 0.6 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 0.6 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
0.0 0.5 GO:0050716 positive regulation of interleukin-1 secretion(GO:0050716)
0.0 0.5 GO:0032897 negative regulation of viral transcription(GO:0032897) negative regulation of viral entry into host cell(GO:0046597)
0.1 0.4 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.1 0.4 GO:0070842 aggresome assembly(GO:0070842)
0.0 0.4 GO:0090179 planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.0 0.3 GO:0060005 vestibular reflex(GO:0060005)
0.0 0.3 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.0 0.3 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.3 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.3 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.1 0.2 GO:0016999 antibiotic metabolic process(GO:0016999)
0.1 0.2 GO:0070428 B-1 B cell homeostasis(GO:0001922) toll-like receptor 5 signaling pathway(GO:0034146) regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428) protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.1 0.2 GO:0000294 nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay(GO:0000294)

Gene overrepresentation in cellular_component category:

Showing 1 to 18 of 18 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.8 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 0.8 GO:0070552 BRISC complex(GO:0070552)
0.1 0.7 GO:0002081 outer acrosomal membrane(GO:0002081)
0.0 0.5 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.0 0.4 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.1 0.3 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.0 0.3 GO:0005610 laminin-5 complex(GO:0005610)
0.0 0.3 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.2 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.2 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.2 GO:0070554 synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.0 0.2 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 0.2 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 0.1 GO:0016939 kinesin II complex(GO:0016939)
0.0 0.1 GO:0005927 muscle tendon junction(GO:0005927)
0.0 0.1 GO:0000801 central element(GO:0000801)
0.0 0.1 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.0 0.0 GO:0031523 Myb complex(GO:0031523)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 48 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.9 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 1.5 GO:0032395 MHC class II receptor activity(GO:0032395)
0.1 0.8 GO:0008732 glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.1 0.7 GO:0032190 manganese ion transmembrane transporter activity(GO:0005384) acrosin binding(GO:0032190)
0.0 0.7 GO:0038191 neuropilin binding(GO:0038191)
0.2 0.6 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.0 0.6 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.5 GO:0042056 chemoattractant activity(GO:0042056)
0.1 0.4 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.1 0.4 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.0 0.4 GO:0070628 proteasome binding(GO:0070628)
0.0 0.3 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.3 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.1 0.2 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.0 0.2 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.2 GO:0070573 metallodipeptidase activity(GO:0070573)
0.0 0.2 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 0.2 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.2 GO:0030884 lipid antigen binding(GO:0030882) endogenous lipid antigen binding(GO:0030883) exogenous lipid antigen binding(GO:0030884)
0.0 0.2 GO:1990763 arrestin family protein binding(GO:1990763)

Gene overrepresentation in C2:CP category:

Showing 1 to 6 of 6 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.9 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.0 0.6 PID_S1P_S1P1_PATHWAY S1P1 pathway
0.0 0.5 PID_NFKAPPAB_CANONICAL_PATHWAY Canonical NF-kappaB pathway
0.0 0.3 PID_INTEGRIN4_PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.2 ST_STAT3_PATHWAY STAT3 Pathway
0.0 0.1 PID_IL5_PATHWAY IL5-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 11 of 11 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.8 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.9 REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.7 REACTOME_TRANSLOCATION_OF_ZAP_70_TO_IMMUNOLOGICAL_SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 0.7 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.7 REACTOME_RIP_MEDIATED_NFKB_ACTIVATION_VIA_DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.6 REACTOME_NOD1_2_SIGNALING_PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.4 REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.2 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.2 REACTOME_IL_6_SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.1 REACTOME_G_PROTEIN_ACTIVATION Genes involved in G-protein activation
0.0 0.1 REACTOME_REGULATION_OF_IFNG_SIGNALING Genes involved in Regulation of IFNG signaling