Motif ID: RORA

Z-value: 0.312


Transcription factors associated with RORA:

Gene SymbolEntrez IDGene Name
RORA ENSG00000069667.11 RORA

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
RORAhg19_v2_chr15_-_60884706_608847430.116.1e-01Click!


Activity profile for motif RORA.

activity profile for motif RORA


Sorted Z-values histogram for motif RORA

Sorted Z-values for motif RORA



Network of associatons between targets according to the STRING database.



First level regulatory network of RORA

PNG image of the network

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Top targets:


Showing 1 to 20 of 183 entries
PromoterScoreRefseqGene SymbolGene Name
chr10_+_77056134 0.496 ENST00000528121.1
ENST00000416398.1
 ZNF503-AS1

ZNF503 antisense RNA 1

chr16_+_777118 0.473 ENST00000562141.1
 HAGHL
hydroxyacylglutathione hydrolase-like
chr1_+_104293028 0.344 ENST00000370079.3
 AMY1C
amylase, alpha 1C (salivary)
chr7_-_128415844 0.336 ENST00000249389.2
 OPN1SW
opsin 1 (cone pigments), short-wave-sensitive
chr1_+_104159999 0.330 ENST00000414303.2
ENST00000423678.1
 AMY2A

amylase, alpha 2A (pancreatic)

chr12_+_93963590 0.312 ENST00000340600.2
 SOCS2
suppressor of cytokine signaling 2
chr12_+_93964158 0.307 ENST00000549206.1
 SOCS2
suppressor of cytokine signaling 2
chr19_-_49140609 0.288 ENST00000601104.1
 DBP
D site of albumin promoter (albumin D-box) binding protein
chr2_+_219472488 0.271 ENST00000450993.2
 PLCD4
phospholipase C, delta 4
chr12_-_53320245 0.246 ENST00000552150.1
 KRT8
keratin 8
chr19_-_49552006 0.233 ENST00000391869.3
 CGB1
chorionic gonadotropin, beta polypeptide 1
chr15_-_72767490 0.226 ENST00000565181.1
 RP11-1007O24.3
RP11-1007O24.3
chr1_+_229440129 0.224 ENST00000366688.3
 SPHAR
S-phase response (cyclin related)
chr21_-_46330545 0.204 ENST00000320216.6
ENST00000397852.1
 ITGB2

integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)

chr7_+_100612904 0.189 ENST00000379442.3
ENST00000536621.1
 MUC12

mucin 12, cell surface associated

chr15_+_43809797 0.184 ENST00000399453.1
ENST00000300231.5
 MAP1A

microtubule-associated protein 1A

chrX_+_18725758 0.183 ENST00000472826.1
ENST00000544635.1
ENST00000496075.2
 PPEF1


protein phosphatase, EF-hand calcium binding domain 1


chr16_-_49698136 0.183 ENST00000535559.1
 ZNF423
zinc finger protein 423
chr9_-_39239171 0.172 ENST00000358144.2
 CNTNAP3
contactin associated protein-like 3
chr10_-_94050820 0.165 ENST00000265997.4
 CPEB3
cytoplasmic polyadenylation element binding protein 3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 18 of 18 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.6 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.3 GO:0044245 polysaccharide digestion(GO:0044245)
0.0 0.3 GO:0018298 protein-chromophore linkage(GO:0018298)
0.1 0.2 GO:1900365 positive regulation of mRNA polyadenylation(GO:1900365)
0.0 0.2 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.2 GO:0051599 response to hydrostatic pressure(GO:0051599)
0.0 0.1 GO:0045082 positive regulation of interleukin-10 biosynthetic process(GO:0045082)
0.0 0.1 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.1 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0 0.1 GO:1904844 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.0 0.1 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.0 0.1 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.0 0.1 GO:0072156 distal tubule morphogenesis(GO:0072156)
0.0 0.1 GO:0090299 regulation of neural crest formation(GO:0090299) negative regulation of neural crest formation(GO:0090301) negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
0.0 0.1 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.0 0.1 GO:0061055 myotome development(GO:0061055)
0.0 0.0 GO:1903028 positive regulation of opsonization(GO:1903028)
0.0 0.0 GO:0019046 release from viral latency(GO:0019046)

Gene overrepresentation in cellular_component category:

Showing 1 to 8 of 8 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.2 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.0 0.2 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.1 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.0 0.1 GO:0005607 laminin-2 complex(GO:0005607)
0.0 0.1 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.0 0.1 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
0.0 0.1 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.1 GO:1990425 ryanodine receptor complex(GO:1990425)

Gene overrepresentation in molecular_function category:

Showing 1 to 16 of 16 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 0.6 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.1 0.3 GO:0016160 amylase activity(GO:0016160)
0.0 0.3 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.2 GO:0030369 ICAM-3 receptor activity(GO:0030369)
0.0 0.2 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.1 GO:0033867 Fas-activated serine/threonine kinase activity(GO:0033867)
0.0 0.1 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.0 0.1 GO:0052593 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.0 0.1 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.0 0.1 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.0 0.1 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0 0.1 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.1 GO:0048763 calcium-induced calcium release activity(GO:0048763)
0.0 0.0 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.0 GO:0050613 delta14-sterol reductase activity(GO:0050613)
0.0 0.0 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 3 of 3 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 0.7 REACTOME_DIGESTION_OF_DIETARY_CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.6 REACTOME_GROWTH_HORMONE_RECEPTOR_SIGNALING Genes involved in Growth hormone receptor signaling
0.0 0.3 REACTOME_OPSINS Genes involved in Opsins