Motif ID: SIX1_SIX3_SIX2

Z-value: 0.501

Transcription factors associated with SIX1_SIX3_SIX2:

Gene SymbolEntrez IDGene Name
SIX1 ENSG00000126778.7 SIX1
SIX2 ENSG00000170577.7 SIX2
SIX3 ENSG00000138083.3 SIX3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
SIX3hg19_v2_chr2_+_45168875_451689160.272.0e-01Click!
SIX1hg19_v2_chr14_-_61124977_611250370.087.0e-01Click!
SIX2hg19_v2_chr2_-_45236540_45236577-0.058.2e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of SIX1_SIX3_SIX2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_-_58499434 0.754 ENST00000344743.3
ENST00000278400.3
GLYAT

glycine-N-acyltransferase

chr1_-_13115578 0.733 ENST00000414205.2
PRAMEF6
PRAME family member 6
chr1_-_13117736 0.645 ENST00000376192.5
ENST00000376182.1
PRAMEF6

PRAME family member 6

chr1_+_13359819 0.616 ENST00000376168.1
PRAMEF5
PRAME family member 5
chr11_-_32452357 0.597 ENST00000379079.2
ENST00000530998.1
WT1

Wilms tumor 1

chr20_-_55100981 0.546 ENST00000243913.4
GCNT7
glucosaminyl (N-acetyl) transferase family member 7
chr9_+_12693336 0.504 ENST00000381137.2
ENST00000388918.5
TYRP1

tyrosinase-related protein 1

chr6_-_76203454 0.486 ENST00000237172.7
FILIP1
filamin A interacting protein 1
chr1_+_26737253 0.464 ENST00000326279.6
LIN28A
lin-28 homolog A (C. elegans)
chr7_+_123241908 0.453 ENST00000434204.1
ENST00000437535.1
ENST00000451215.1
ASB15


ankyrin repeat and SOCS box containing 15


chr1_+_26737292 0.443 ENST00000254231.4
LIN28A
lin-28 homolog A (C. elegans)
chr1_-_240906911 0.443 ENST00000431139.2
RP11-80B9.4
RP11-80B9.4
chr19_+_41594377 0.421 ENST00000330436.3
CYP2A13
cytochrome P450, family 2, subfamily A, polypeptide 13
chr13_-_46679185 0.415 ENST00000439329.3
CPB2
carboxypeptidase B2 (plasma)
chrX_-_65259914 0.410 ENST00000374737.4
ENST00000455586.2
VSIG4

V-set and immunoglobulin domain containing 4

chrX_-_65259900 0.408 ENST00000412866.2
VSIG4
V-set and immunoglobulin domain containing 4
chr13_-_46679144 0.406 ENST00000181383.4
CPB2
carboxypeptidase B2 (plasma)
chr1_+_241695424 0.400 ENST00000366558.3
ENST00000366559.4
KMO

kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)

chr2_-_207629997 0.386 ENST00000454776.2
MDH1B
malate dehydrogenase 1B, NAD (soluble)
chrX_+_101470280 0.374 ENST00000395088.2
ENST00000330252.5
ENST00000333110.5
NXF2

TCP11X1
nuclear RNA export factor 2

t-complex 11 family, X-linked 1
chr2_-_207630033 0.370 ENST00000449792.1
MDH1B
malate dehydrogenase 1B, NAD (soluble)
chr11_+_73661364 0.360 ENST00000339764.1
DNAJB13
DnaJ (Hsp40) homolog, subfamily B, member 13
chr14_+_22739823 0.353 ENST00000390464.2
TRAV38-1
T cell receptor alpha variable 38-1
chr12_+_49121213 0.332 ENST00000548380.1
LINC00935
long intergenic non-protein coding RNA 935
chr21_+_27011899 0.331 ENST00000425221.2
JAM2
junctional adhesion molecule 2
chr1_-_12946025 0.328 ENST00000235349.5
PRAMEF4
PRAME family member 4
chr1_-_13007420 0.322 ENST00000376189.1
PRAMEF6
PRAME family member 6
chr3_-_46506358 0.317 ENST00000417439.1
ENST00000431944.1
LTF

lactotransferrin

chr3_+_118866222 0.313 ENST00000490594.1
RP11-484M3.5
Uncharacterized protein
chr1_+_182419261 0.307 ENST00000294854.8
ENST00000542961.1
RGSL1

regulator of G-protein signaling like 1

chr19_-_58446721 0.288 ENST00000396147.1
ENST00000595569.1
ENST00000599852.1
ENST00000425570.3
ENST00000601593.1
ZNF418




zinc finger protein 418




chr7_-_14880892 0.284 ENST00000406247.3
ENST00000399322.3
ENST00000258767.5
DGKB


diacylglycerol kinase, beta 90kDa


chr18_+_61575200 0.270 ENST00000238508.3
SERPINB10
serpin peptidase inhibitor, clade B (ovalbumin), member 10
chr1_+_241695670 0.264 ENST00000366557.4
KMO
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr15_+_40650408 0.262 ENST00000267889.3
DISP2
dispatched homolog 2 (Drosophila)
chr14_-_24911448 0.257 ENST00000555355.1
ENST00000553343.1
ENST00000556523.1
ENST00000556249.1
ENST00000538105.2
ENST00000555225.1
SDR39U1





short chain dehydrogenase/reductase family 39U, member 1





chr12_-_55378452 0.256 ENST00000449076.1
TESPA1
thymocyte expressed, positive selection associated 1
chr8_+_118147498 0.256 ENST00000519688.1
ENST00000456015.2
SLC30A8

solute carrier family 30 (zinc transporter), member 8

chr11_+_71791359 0.254 ENST00000419228.1
ENST00000435085.1
ENST00000307198.7
ENST00000538413.1
LRTOMT



leucine rich transmembrane and O-methyltransferase domain containing



chr14_+_62462541 0.254 ENST00000430451.2
SYT16
synaptotagmin XVI
chr1_-_44818599 0.250 ENST00000537474.1
ERI3
ERI1 exoribonuclease family member 3
chr1_-_60539422 0.246 ENST00000371201.3
C1orf87
chromosome 1 open reading frame 87
chr10_-_134331695 0.241 ENST00000455414.1
RP11-432J24.5
RP11-432J24.5
chr10_-_103603523 0.236 ENST00000370046.1
KCNIP2
Kv channel interacting protein 2
chr11_-_35547151 0.230 ENST00000378878.3
ENST00000529303.1
ENST00000278360.3
PAMR1


peptidase domain containing associated with muscle regeneration 1


chr2_-_105953912 0.229 ENST00000610036.1
RP11-332H14.2
RP11-332H14.2
chr1_-_27998689 0.229 ENST00000339145.4
ENST00000362020.4
ENST00000361157.6
IFI6


interferon, alpha-inducible protein 6


chr3_+_149191723 0.226 ENST00000305354.4
TM4SF4
transmembrane 4 L six family member 4
chr3_-_19975665 0.219 ENST00000295824.9
ENST00000389256.4
EFHB

EF-hand domain family, member B

chr1_+_160709029 0.216 ENST00000444090.2
ENST00000441662.2
SLAMF7

SLAM family member 7

chr12_+_51236703 0.213 ENST00000551456.1
ENST00000398458.3
TMPRSS12

transmembrane (C-terminal) protease, serine 12

chr8_-_134115118 0.200 ENST00000395352.3
ENST00000338087.5
SLA

Src-like-adaptor

chr21_-_35883613 0.199 ENST00000337385.3
KCNE1
potassium voltage-gated channel, Isk-related family, member 1
chr10_-_103603568 0.195 ENST00000356640.2
KCNIP2
Kv channel interacting protein 2
chr17_-_3030875 0.194 ENST00000328890.2
OR1G1
olfactory receptor, family 1, subfamily G, member 1
chr1_+_78769549 0.191 ENST00000370758.1
PTGFR
prostaglandin F receptor (FP)
chr10_+_7745232 0.189 ENST00000358415.4
ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr4_+_70894130 0.185 ENST00000526767.1
ENST00000530128.1
ENST00000381057.3
HTN3


histatin 3


chr19_+_11457175 0.184 ENST00000458408.1
ENST00000586451.1
ENST00000588592.1
CCDC159


coiled-coil domain containing 159


chr1_+_35225339 0.183 ENST00000339480.1
GJB4
gap junction protein, beta 4, 30.3kDa
chr7_+_138915102 0.183 ENST00000486663.1
UBN2
ubinuclein 2
chr1_-_183387723 0.181 ENST00000287713.6
NMNAT2
nicotinamide nucleotide adenylyltransferase 2
chr1_-_169337176 0.181 ENST00000472647.1
ENST00000367811.3
NME7

NME/NM23 family member 7

chr17_-_55911970 0.176 ENST00000581805.1
ENST00000580960.1
RP11-60A24.3

RP11-60A24.3

chr1_-_108743471 0.174 ENST00000569674.1
SLC25A24
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
chr10_+_7745303 0.168 ENST00000429820.1
ENST00000379587.4
ITIH2

inter-alpha-trypsin inhibitor heavy chain 2

chr1_+_160709055 0.167 ENST00000368043.3
ENST00000368042.3
ENST00000458602.2
ENST00000458104.2
SLAMF7



SLAM family member 7



chr14_-_95942173 0.163 ENST00000334258.5
ENST00000557275.1
ENST00000553340.1
SYNE3


spectrin repeat containing, nuclear envelope family member 3


chr8_+_76452097 0.162 ENST00000396423.2
HNF4G
hepatocyte nuclear factor 4, gamma
chr1_-_207119738 0.161 ENST00000356495.4
PIGR
polymeric immunoglobulin receptor
chr19_-_54872556 0.161 ENST00000444687.1
LAIR1
leukocyte-associated immunoglobulin-like receptor 1
chr6_-_167797887 0.159 ENST00000476779.2
ENST00000460930.2
ENST00000397829.4
ENST00000366827.2
TCP10



t-complex 10



chr3_+_111718036 0.156 ENST00000455401.2
TAGLN3
transgelin 3
chr16_+_21695750 0.156 ENST00000388956.4
OTOA
otoancorin
chr2_-_209010874 0.155 ENST00000260988.4
CRYGB
crystallin, gamma B
chr8_+_99129513 0.155 ENST00000522319.1
ENST00000401707.2
POP1

processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae)

chr1_+_6684918 0.154 ENST00000054650.4
THAP3
THAP domain containing, apoptosis associated protein 3
chr4_+_80748619 0.152 ENST00000504263.1
PCAT4
prostate cancer associated transcript 4 (non-protein coding)
chr1_+_15256230 0.150 ENST00000376028.4
ENST00000400798.2
KAZN

kazrin, periplakin interacting protein

chr1_+_38022572 0.146 ENST00000541606.1
DNALI1
dynein, axonemal, light intermediate chain 1
chr11_-_5364809 0.145 ENST00000300773.2
OR51B5
olfactory receptor, family 51, subfamily B, member 5
chr3_+_26735991 0.144 ENST00000456208.2
LRRC3B
leucine rich repeat containing 3B
chr19_+_56459198 0.144 ENST00000291971.3
ENST00000590542.1
NLRP8

NLR family, pyrin domain containing 8

chr1_+_196743912 0.144 ENST00000367425.4
CFHR3
complement factor H-related 3
chr10_-_103603677 0.143 ENST00000358038.3
KCNIP2
Kv channel interacting protein 2
chr9_-_27005686 0.142 ENST00000380055.5
LRRC19
leucine rich repeat containing 19
chr1_-_157670528 0.139 ENST00000368186.5
ENST00000496769.1
FCRL3

Fc receptor-like 3

chr5_+_161112754 0.139 ENST00000523217.1
GABRA6
gamma-aminobutyric acid (GABA) A receptor, alpha 6
chr1_+_160709076 0.137 ENST00000359331.4
ENST00000495334.1
SLAMF7

SLAM family member 7

chr5_-_132073210 0.137 ENST00000378735.1
ENST00000378746.4
KIF3A

kinesin family member 3A

chr3_+_111718173 0.135 ENST00000494932.1
TAGLN3
transgelin 3
chr1_+_207277590 0.133 ENST00000367070.3
C4BPA
complement component 4 binding protein, alpha
chr3_+_111717600 0.131 ENST00000273368.4
TAGLN3
transgelin 3
chr19_+_11457232 0.131 ENST00000587531.1
CCDC159
coiled-coil domain containing 159
chr14_+_58711539 0.129 ENST00000216455.4
ENST00000412908.2
ENST00000557508.1
PSMA3


proteasome (prosome, macropain) subunit, alpha type, 3


chr6_+_31554636 0.126 ENST00000433492.1
LST1
leukocyte specific transcript 1
chr22_+_22936998 0.124 ENST00000390303.2
IGLV3-32
immunoglobulin lambda variable 3-32 (non-functional)
chr1_-_67266939 0.124 ENST00000304526.2
INSL5
insulin-like 5
chr8_+_94767072 0.123 ENST00000452276.1
ENST00000453321.3
ENST00000498673.1
ENST00000518319.1
TMEM67



transmembrane protein 67



chr17_-_8151353 0.121 ENST00000315684.8
CTC1
CTS telomere maintenance complex component 1
chr21_-_34185944 0.120 ENST00000479548.1
C21orf62
chromosome 21 open reading frame 62
chr18_-_6929797 0.120 ENST00000581725.1
ENST00000583316.1
LINC00668

long intergenic non-protein coding RNA 668

chr1_+_40942887 0.120 ENST00000372706.1
ZFP69
ZFP69 zinc finger protein
chr3_+_42850959 0.118 ENST00000442925.1
ENST00000422265.1
ENST00000497921.1
ENST00000426937.1
ACKR2


KRBOX1
atypical chemokine receptor 2


KRAB box domain containing 1
chr21_+_27011584 0.117 ENST00000400532.1
ENST00000480456.1
ENST00000312957.5
JAM2


junctional adhesion molecule 2


chrX_+_144908928 0.116 ENST00000408967.2
TMEM257
transmembrane protein 257
chr19_-_55549624 0.111 ENST00000417454.1
ENST00000310373.3
ENST00000333884.2
GP6


glycoprotein VI (platelet)


chrX_-_72095808 0.107 ENST00000373529.5
DMRTC1
DMRT-like family C1
chr9_-_79307096 0.107 ENST00000376717.2
ENST00000223609.6
ENST00000443509.2
PRUNE2


prune homolog 2 (Drosophila)


chr11_+_125365110 0.106 ENST00000527818.1
AP000708.1
AP000708.1
chr1_+_13421176 0.106 ENST00000376152.1
PRAMEF9
PRAME family member 9
chr4_+_89299994 0.103 ENST00000264346.7
HERC6
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
chr13_-_60737898 0.103 ENST00000377908.2
ENST00000400319.1
ENST00000400320.1
ENST00000267215.4
DIAPH3



diaphanous-related formin 3



chr17_+_6659153 0.103 ENST00000441631.1
ENST00000438512.1
ENST00000346752.4
ENST00000361842.3
XAF1



XIAP associated factor 1



chr11_+_64323428 0.103 ENST00000377581.3
SLC22A11
solute carrier family 22 (organic anion/urate transporter), member 11
chr6_+_88757507 0.102 ENST00000237201.1
SPACA1
sperm acrosome associated 1
chr6_-_32160622 0.100 ENST00000487761.1
ENST00000375040.3
GPSM3

G-protein signaling modulator 3

chr1_-_57285038 0.100 ENST00000343433.6
C1orf168
chromosome 1 open reading frame 168
chr20_+_34824355 0.099 ENST00000397286.3
ENST00000320849.4
ENST00000373932.3
AAR2


AAR2 splicing factor homolog (S. cerevisiae)


chr19_+_55476620 0.098 ENST00000543010.1
ENST00000391721.4
ENST00000339757.7
NLRP2


NLR family, pyrin domain containing 2


chr17_-_72527605 0.098 ENST00000392621.1
ENST00000314401.3
CD300LB

CD300 molecule-like family member b

chr12_+_100750846 0.098 ENST00000323346.5
SLC17A8
solute carrier family 17 (vesicular glutamate transporter), member 8
chr2_-_220034745 0.097 ENST00000455516.2
ENST00000396775.3
ENST00000295738.7
SLC23A3


solute carrier family 23, member 3


chr2_+_219536749 0.097 ENST00000295709.3
ENST00000392106.2
ENST00000392105.3
ENST00000455724.1
STK36



serine/threonine kinase 36



chr6_+_31554779 0.095 ENST00000376090.2
LST1
leukocyte specific transcript 1
chr12_-_53594227 0.095 ENST00000550743.2
ITGB7
integrin, beta 7
chrX_-_152864632 0.094 ENST00000406277.2
FAM58A
family with sequence similarity 58, member A
chr17_+_32646055 0.092 ENST00000394620.1
CCL8
chemokine (C-C motif) ligand 8
chr12_-_323689 0.091 ENST00000428720.1
SLC6A12
solute carrier family 6 (neurotransmitter transporter), member 12
chr14_+_22771851 0.091 ENST00000390466.1
TRAV39
T cell receptor alpha variable 39
chr1_-_159046617 0.091 ENST00000368130.4
AIM2
absent in melanoma 2
chr11_-_118436707 0.090 ENST00000264020.2
ENST00000264021.3
IFT46

intraflagellar transport 46 homolog (Chlamydomonas)

chrX_+_8432871 0.090 ENST00000381032.1
ENST00000453306.1
ENST00000444481.1
VCX3B


variable charge, X-linked 3B


chr7_-_44198874 0.089 ENST00000395796.3
ENST00000345378.2
GCK

glucokinase (hexokinase 4)

chr5_-_35195338 0.089 ENST00000509839.1
PRLR
prolactin receptor
chr11_-_76155618 0.089 ENST00000530759.1
RP11-111M22.3
RP11-111M22.3
chr4_-_156298028 0.088 ENST00000433024.1
ENST00000379248.2
MAP9

microtubule-associated protein 9

chr8_-_95487272 0.088 ENST00000297592.5
RAD54B
RAD54 homolog B (S. cerevisiae)
chr12_-_57882577 0.086 ENST00000393797.2
ARHGAP9
Rho GTPase activating protein 9
chr19_+_46800289 0.086 ENST00000377670.4
HIF3A
hypoxia inducible factor 3, alpha subunit
chr17_-_33446735 0.085 ENST00000460118.2
ENST00000335858.7
RAD51D

RAD51 paralog D

chr15_+_81426588 0.084 ENST00000286732.4
C15orf26
chromosome 15 open reading frame 26
chr19_-_36606181 0.084 ENST00000221859.4
POLR2I
polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
chr8_-_25902876 0.084 ENST00000520164.1
EBF2
early B-cell factor 2
chr14_+_73563735 0.083 ENST00000532192.1
RBM25
RNA binding motif protein 25
chr9_-_95186739 0.083 ENST00000375550.4
OMD
osteomodulin
chr14_+_78266408 0.083 ENST00000238561.5
ADCK1
aarF domain containing kinase 1
chr9_+_132427883 0.082 ENST00000372469.4
PRRX2
paired related homeobox 2
chr14_+_78266436 0.082 ENST00000557501.1
ENST00000341211.5
ADCK1

aarF domain containing kinase 1

chr3_-_129147432 0.082 ENST00000503957.1
ENST00000505956.1
ENST00000326085.3
EFCAB12


EF-hand calcium binding domain 12


chr2_-_25391507 0.081 ENST00000380794.1
POMC
proopiomelanocortin
chr12_+_20848377 0.081 ENST00000540354.1
ENST00000266509.2
ENST00000381552.1
SLCO1C1


solute carrier organic anion transporter family, member 1C1


chr10_-_96122682 0.081 ENST00000371361.3
NOC3L
nucleolar complex associated 3 homolog (S. cerevisiae)
chr1_-_208084729 0.080 ENST00000310833.7
ENST00000356522.4
CD34

CD34 molecule

chr11_+_64323156 0.080 ENST00000377585.3
SLC22A11
solute carrier family 22 (organic anion/urate transporter), member 11
chr11_+_71900572 0.080 ENST00000312293.4
FOLR1
folate receptor 1 (adult)
chr6_-_52710893 0.079 ENST00000284562.2
GSTA5
glutathione S-transferase alpha 5
chr9_+_84603687 0.078 ENST00000344803.2
SPATA31D1
SPATA31 subfamily D, member 1
chr7_+_29519486 0.078 ENST00000409041.4
CHN2
chimerin 2
chr21_-_33957805 0.077 ENST00000300258.3
ENST00000472557.1
TCP10L

t-complex 10-like

chr11_+_64323098 0.076 ENST00000301891.4
SLC22A11
solute carrier family 22 (organic anion/urate transporter), member 11
chr7_-_141541221 0.076 ENST00000350549.3
ENST00000438520.1
PRSS37

protease, serine, 37

chr17_+_4675175 0.076 ENST00000270560.3
TM4SF5
transmembrane 4 L six family member 5
chr5_-_145562147 0.075 ENST00000545646.1
ENST00000274562.9
ENST00000510191.1
ENST00000394434.2
LARS



leucyl-tRNA synthetase



chr22_+_32455111 0.075 ENST00000543737.1
SLC5A1
solute carrier family 5 (sodium/glucose cotransporter), member 1
chr3_+_44754126 0.074 ENST00000449836.1
ENST00000436624.2
ENST00000296091.4
ENST00000411443.1
ZNF502



zinc finger protein 502



chr3_+_197687071 0.073 ENST00000482695.1
ENST00000330198.4
ENST00000419117.1
ENST00000420910.2
ENST00000332636.5
LMLN




leishmanolysin-like (metallopeptidase M8 family)




chr6_+_131894284 0.071 ENST00000368087.3
ENST00000356962.2
ARG1

arginase 1

chrX_+_114524275 0.071 ENST00000371921.1
ENST00000451986.2
ENST00000371920.3
LUZP4


leucine zipper protein 4


chr14_+_51026743 0.069 ENST00000358385.6
ENST00000357032.3
ENST00000354525.4
ATL1


atlastin GTPase 1


chr11_-_76155700 0.067 ENST00000572035.1
RP11-111M22.3
RP11-111M22.3
chr16_-_15463926 0.066 ENST00000432570.2
NPIPA5
nuclear pore complex interacting protein family, member A5
chr4_+_78829479 0.066 ENST00000504901.1
MRPL1
mitochondrial ribosomal protein L1
chr19_+_36606354 0.066 ENST00000589996.1
ENST00000591296.1
TBCB

tubulin folding cofactor B

chr7_+_142498725 0.065 ENST00000466254.1
TRBC2
T cell receptor beta constant 2
chr14_-_24615805 0.065 ENST00000560410.1
PSME2
proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
chr16_+_88636789 0.065 ENST00000301011.5
ENST00000452588.2
ZC3H18

zinc finger CCCH-type containing 18

chr19_-_48389651 0.065 ENST00000222002.3
SULT2A1
sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1
chr17_-_58096336 0.064 ENST00000587125.1
ENST00000407042.3
TBC1D3P1-DHX40P1

TBC1D3P1-DHX40P1 readthrough transcribed pseudogene

chr17_+_35732955 0.064 ENST00000300618.4
C17orf78
chromosome 17 open reading frame 78
chr16_+_84801852 0.063 ENST00000569925.1
ENST00000567526.1
USP10

ubiquitin specific peptidase 10

chr4_+_159131346 0.063 ENST00000508243.1
ENST00000296529.6
TMEM144

transmembrane protein 144

chr19_+_16222439 0.063 ENST00000300935.3
RAB8A
RAB8A, member RAS oncogene family
chr12_-_6798616 0.063 ENST00000355772.4
ENST00000417772.3
ENST00000396801.3
ENST00000396799.2
ZNF384



zinc finger protein 384



chr10_-_6622258 0.062 ENST00000263125.5
PRKCQ
protein kinase C, theta
chr18_-_11148587 0.062 ENST00000302079.6
ENST00000580640.1
ENST00000503781.3
PIEZO2


piezo-type mechanosensitive ion channel component 2


chr4_-_156298087 0.061 ENST00000311277.4
MAP9
microtubule-associated protein 9
chr12_-_5352315 0.060 ENST00000536518.1
RP11-319E16.1
RP11-319E16.1
chr1_+_87595542 0.060 ENST00000461990.1
RP5-1052I5.1
long intergenic non-protein coding RNA 1140
chr12_-_54758251 0.059 ENST00000267015.3
ENST00000551809.1
GPR84

G protein-coupled receptor 84

chr6_+_31583761 0.058 ENST00000376049.4
AIF1
allograft inflammatory factor 1
chr12_-_11036844 0.057 ENST00000428168.2
PRH1
proline-rich protein HaeIII subfamily 1
chr17_-_6915646 0.057 ENST00000574377.1
ENST00000399541.2
ENST00000399540.2
ENST00000575727.1
ENST00000573939.1
AC027763.2




Uncharacterized protein




chr3_+_178253993 0.057 ENST00000420517.2
ENST00000452583.1
KCNMB2

potassium large conductance calcium-activated channel, subfamily M, beta member 2

chrX_+_56259316 0.057 ENST00000468660.1
KLF8
Kruppel-like factor 8
chr19_-_50266580 0.056 ENST00000246801.3
TSKS
testis-specific serine kinase substrate
chr6_+_31554962 0.056 ENST00000376092.3
ENST00000376086.3
ENST00000303757.8
ENST00000376093.2
ENST00000376102.3
LST1




leukocyte specific transcript 1




chr15_+_80733570 0.056 ENST00000533983.1
ENST00000527771.1
ENST00000525103.1
ARNT2


aryl-hydrocarbon receptor nuclear translocator 2


chr3_-_10452359 0.055 ENST00000452124.1
ATP2B2
ATPase, Ca++ transporting, plasma membrane 2
chr4_-_83719884 0.055 ENST00000282709.4
ENST00000273908.4
SCD5

stearoyl-CoA desaturase 5


Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0003331 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.1 0.6 GO:0072299 negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302)
0.1 0.9 GO:0010587 miRNA catabolic process(GO:0010587)
0.1 0.3 GO:0033214 iron assimilation(GO:0033212) iron assimilation by chelation and transport(GO:0033214) positive regulation of bone mineralization involved in bone maturation(GO:1900159) negative regulation of tumor necrosis factor (ligand) superfamily member 11 production(GO:2000308)
0.1 0.7 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.1 0.6 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.1 0.4 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.1 0.3 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.1 0.4 GO:0009804 coumarin metabolic process(GO:0009804)
0.1 0.8 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.5 GO:0048023 positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.0 0.2 GO:0019355 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process(GO:0034627) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.0 0.2 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.0 0.9 GO:0032703 negative regulation of interleukin-2 production(GO:0032703)
0.0 0.1 GO:0003147 neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713)
0.0 0.3 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 0.1 GO:0006425 glutaminyl-tRNA aminoacylation(GO:0006425)
0.0 0.1 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.0 0.2 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.0 0.2 GO:0016078 tRNA catabolic process(GO:0016078)
0.0 0.2 GO:0071798 response to prostaglandin D(GO:0071798) cellular response to prostaglandin D stimulus(GO:0071799)
0.0 0.2 GO:1902412 regulation of mitotic cytokinesis(GO:1902412)
0.0 0.2 GO:0051902 negative regulation of mitochondrial depolarization(GO:0051902)
0.0 0.0 GO:0043449 cellular alkene metabolic process(GO:0043449)
0.0 0.3 GO:0015747 urate transport(GO:0015747)
0.0 0.1 GO:0007228 positive regulation of hh target transcription factor activity(GO:0007228)
0.0 0.1 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.0 0.1 GO:0048539 bone marrow development(GO:0048539)
0.0 0.4 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.0 GO:2001160 regulation of histone H3-K79 methylation(GO:2001160) positive regulation of histone H3-K79 methylation(GO:2001162)
0.0 0.1 GO:0038161 prolactin signaling pathway(GO:0038161)
0.0 0.0 GO:2000017 positive regulation of determination of dorsal identity(GO:2000017)
0.0 0.1 GO:2000569 T-helper 2 cell activation(GO:0035712) regulation of T-helper 2 cell activation(GO:2000569) positive regulation of T-helper 2 cell activation(GO:2000570)
0.0 0.2 GO:0042048 olfactory behavior(GO:0042048)
0.0 0.1 GO:0001951 intestinal D-glucose absorption(GO:0001951)
0.0 0.1 GO:1903027 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959) regulation of opsonization(GO:1903027)
0.0 0.0 GO:0038193 thromboxane A2 signaling pathway(GO:0038193)
0.0 0.1 GO:0043091 L-arginine import(GO:0043091) arginine import(GO:0090467)
0.0 0.2 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.0 GO:0046874 quinolinate metabolic process(GO:0046874)
0.0 0.0 GO:0019417 sulfur oxidation(GO:0019417)
0.0 0.1 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.0 0.1 GO:0009730 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.0 0.2 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260)
0.0 0.0 GO:0035621 ER to Golgi ceramide transport(GO:0035621)
0.0 0.1 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.1 GO:0014738 regulation of muscle hyperplasia(GO:0014738)
0.0 0.1 GO:0015722 canalicular bile acid transport(GO:0015722)
0.0 0.1 GO:0044791 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.0 0.1 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.1 GO:2000852 corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.0 0.3 GO:0097013 phagocytic vesicle lumen(GO:0097013)
0.0 0.1 GO:0016939 kinesin II complex(GO:0016939)
0.0 0.1 GO:0097450 astrocyte end-foot(GO:0097450)
0.0 0.1 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.0 0.2 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.4 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.0 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.1 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.0 GO:0005960 glycine cleavage complex(GO:0005960)
0.0 0.9 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.1 GO:0008537 proteasome activator complex(GO:0008537)
0.0 0.1 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.1 0.6 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.1 0.8 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.1 0.6 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.1 0.9 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.1 0.2 GO:0004958 prostaglandin F receptor activity(GO:0004958)
0.1 0.7 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.2 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309)
0.0 0.1 GO:0032090 Pyrin domain binding(GO:0032090)
0.0 0.1 GO:0004819 glutamine-tRNA ligase activity(GO:0004819)
0.0 0.1 GO:0015616 DNA translocase activity(GO:0015616)
0.0 0.8 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.2 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.0 0.4 GO:0008392 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.0 0.2 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.0 0.1 GO:0051870 methotrexate binding(GO:0051870) folic acid receptor activity(GO:0061714)
0.0 0.1 GO:0004925 prolactin receptor activity(GO:0004925)
0.0 0.3 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.1 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.0 0.2 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.0 0.3 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.1 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 0.1 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.0 GO:0004961 thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
0.0 0.1 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.0 0.1 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.0 0.1 GO:0004966 galanin receptor activity(GO:0004966)
0.0 0.1 GO:0070996 type 1 melanocortin receptor binding(GO:0070996)
0.0 0.0 GO:0004766 spermidine synthase activity(GO:0004766)
0.0 0.1 GO:0004340 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.1 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 REACTOME_TRYPTOPHAN_CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.2 REACTOME_PROSTANOID_LIGAND_RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.3 REACTOME_XENOBIOTICS Genes involved in Xenobiotics
0.0 0.3 REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT Genes involved in Organic cation/anion/zwitterion transport