Motif ID: SOX14

Z-value: 0.489


Transcription factors associated with SOX14:

Gene SymbolEntrez IDGene Name
SOX14 ENSG00000168875.1 SOX14

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
SOX14hg19_v2_chr3_+_137483579_1374835790.106.5e-01Click!


Activity profile for motif SOX14.

activity profile for motif SOX14


Sorted Z-values histogram for motif SOX14

Sorted Z-values for motif SOX14



Network of associatons between targets according to the STRING database.



First level regulatory network of SOX14

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_-_180018540 1.905 ENST00000292641.3
 SCGB3A1
secretoglobin, family 3A, member 1
chr16_-_52580920 1.039 ENST00000219746.9
 TOX3
TOX high mobility group box family member 3
chr5_+_94727048 0.950 ENST00000283357.5
 FAM81B
family with sequence similarity 81, member B
chr15_+_71184931 0.769 ENST00000560369.1
ENST00000260382.5
 LRRC49

leucine rich repeat containing 49

chr1_-_104238912 0.766 ENST00000330330.5
 AMY1B
amylase, alpha 1B (salivary)
chr12_-_71551868 0.750 ENST00000247829.3
 TSPAN8
tetraspanin 8
chr1_+_104198377 0.723 ENST00000370083.4
 AMY1A
amylase, alpha 1A (salivary)
chr10_-_123274693 0.546 ENST00000429361.1
 FGFR2
fibroblast growth factor receptor 2
chr22_-_50970506 0.546 ENST00000428989.2
ENST00000403326.1
 ODF3B

outer dense fiber of sperm tails 3B

chr8_-_110620284 0.484 ENST00000529690.1
 SYBU
syntabulin (syntaxin-interacting)
chr17_+_68100989 0.462 ENST00000585558.1
ENST00000392670.1
 KCNJ16

potassium inwardly-rectifying channel, subfamily J, member 16

chrX_-_2418596 0.445 ENST00000381218.3
 ZBED1
zinc finger, BED-type containing 1
chrX_+_129473859 0.432 ENST00000424447.1
 SLC25A14
solute carrier family 25 (mitochondrial carrier, brain), member 14
chr10_-_13390270 0.407 ENST00000378614.4
ENST00000545675.1
ENST00000327347.5
 SEPHS1


selenophosphate synthetase 1


chr14_+_103589789 0.392 ENST00000558056.1
ENST00000560869.1
 TNFAIP2

tumor necrosis factor, alpha-induced protein 2

chr6_+_138188551 0.392 ENST00000237289.4
ENST00000433680.1
 TNFAIP3

tumor necrosis factor, alpha-induced protein 3

chr6_-_24877490 0.387 ENST00000540914.1
ENST00000378023.4
 FAM65B

family with sequence similarity 65, member B

chr2_+_127413677 0.380 ENST00000356887.7
 GYPC
glycophorin C (Gerbich blood group)
chr7_-_149470540 0.380 ENST00000302017.3
 ZNF467
zinc finger protein 467
chr5_+_140213815 0.376 ENST00000525929.1
ENST00000378125.3
 PCDHA7

protocadherin alpha 7


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 49 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.9 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.0 0.9 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.1 0.7 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.0 0.7 GO:0034389 lipid particle organization(GO:0034389)
0.2 0.5 GO:0035604 fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow(GO:0035602) fibroblast growth factor receptor signaling pathway involved in hemopoiesis(GO:0035603) fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow(GO:0035604)
0.2 0.5 GO:0015817 acyl carnitine transport(GO:0006844) histidine transport(GO:0015817) L-histidine transmembrane transport(GO:0089709) L-histidine transport(GO:1902024) acyl carnitine transmembrane transport(GO:1902616)
0.0 0.5 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.5 GO:0010107 potassium ion import(GO:0010107)
0.1 0.4 GO:0016260 selenocysteine biosynthetic process(GO:0016260)
0.1 0.4 GO:0070428 B-1 B cell homeostasis(GO:0001922) toll-like receptor 5 signaling pathway(GO:0034146) regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428) protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947) negative regulation of osteoclast proliferation(GO:0090291)
0.1 0.4 GO:1904204 regulation of skeletal muscle hypertrophy(GO:1904204)
0.1 0.4 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.4 GO:0051601 exocyst localization(GO:0051601)
0.0 0.4 GO:0006527 arginine catabolic process(GO:0006527)
0.1 0.3 GO:2000583 regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584)
0.1 0.3 GO:0031508 pericentric heterochromatin assembly(GO:0031508)
0.1 0.3 GO:0051866 general adaptation syndrome(GO:0051866)
0.1 0.3 GO:0072156 distal tubule morphogenesis(GO:0072156)
0.0 0.3 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.3 GO:0052695 cellular glucuronidation(GO:0052695)

Gene overrepresentation in cellular_component category:

Showing 1 to 17 of 17 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.9 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 0.7 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.5 GO:0097433 dense body(GO:0097433)
0.1 0.4 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.4 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.0 0.4 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.4 GO:0000145 exocyst(GO:0000145)
0.0 0.3 GO:0001740 Barr body(GO:0001740)
0.0 0.2 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.2 GO:0036128 CatSper complex(GO:0036128)
0.0 0.2 GO:0042382 paraspeckles(GO:0042382)
0.0 0.2 GO:0032039 integrator complex(GO:0032039)
0.0 0.1 GO:0070288 intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.0 0.1 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.1 GO:0016589 NURF complex(GO:0016589)
0.0 0.1 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.1 GO:0030905 retromer, tubulation complex(GO:0030905)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 34 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.0 GO:0034056 estrogen response element binding(GO:0034056)
0.2 0.9 GO:0004803 transposase activity(GO:0004803)
0.1 0.8 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.2 0.7 GO:0016160 amylase activity(GO:0016160)
0.1 0.7 GO:0046979 TAP2 binding(GO:0046979)
0.2 0.5 GO:0015227 acyl carnitine transmembrane transporter activity(GO:0015227)
0.0 0.5 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.5 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.5 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.5 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 0.4 GO:0016781 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.1 0.4 GO:0016403 dimethylargininase activity(GO:0016403)
0.0 0.4 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.4 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.4 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.3 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0 0.3 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.2 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.2 GO:0043398 HLH domain binding(GO:0043398)
0.0 0.2 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)

Gene overrepresentation in C2:CP category:

Showing 1 to 3 of 3 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.9 PID_ATR_PATHWAY ATR signaling pathway
0.0 0.7 PID_CD40_PATHWAY CD40/CD40L signaling
0.0 0.2 PID_EPHB_FWD_PATHWAY EPHB forward signaling

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 8 of 8 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 1.5 REACTOME_DIGESTION_OF_DIETARY_CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.1 0.7 REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.6 REACTOME_CRMPS_IN_SEMA3A_SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.5 REACTOME_FGFR2C_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR2c ligand binding and activation
0.0 0.5 REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.4 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.3 REACTOME_GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.2 REACTOME_OPSINS Genes involved in Opsins