Motif ID: SOX18
Z-value: 0.881

Transcription factors associated with SOX18:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
SOX18 | ENSG00000203883.5 | SOX18 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
SOX18 | hg19_v2_chr20_-_62680984_62680999 | 0.02 | 9.2e-01 | Click! |
Top targets:
Showing 1 to 20 of 200 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 89 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 3.5 | GO:0006939 | smooth muscle contraction(GO:0006939) |
0.5 | 3.3 | GO:0061370 | testosterone biosynthetic process(GO:0061370) |
0.0 | 3.2 | GO:0010812 | negative regulation of cell-substrate adhesion(GO:0010812) |
0.2 | 3.0 | GO:0050861 | positive regulation of B cell receptor signaling pathway(GO:0050861) |
0.0 | 3.0 | GO:0007565 | female pregnancy(GO:0007565) |
0.0 | 2.8 | GO:0050911 | detection of chemical stimulus involved in sensory perception of smell(GO:0050911) |
0.1 | 2.7 | GO:0006346 | methylation-dependent chromatin silencing(GO:0006346) |
0.4 | 2.2 | GO:0070995 | NADPH oxidation(GO:0070995) |
0.0 | 2.2 | GO:0048813 | dendrite morphogenesis(GO:0048813) |
0.1 | 2.1 | GO:1900363 | regulation of mRNA polyadenylation(GO:1900363) |
0.1 | 2.0 | GO:0001829 | trophectodermal cell differentiation(GO:0001829) |
0.1 | 1.8 | GO:0070234 | positive regulation of T cell apoptotic process(GO:0070234) |
0.0 | 1.8 | GO:0001580 | detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580) |
0.2 | 1.7 | GO:1905150 | regulation of voltage-gated sodium channel activity(GO:1905150) |
0.1 | 1.2 | GO:0000338 | protein deneddylation(GO:0000338) |
0.2 | 1.1 | GO:0052551 | response to defense-related nitric oxide production by other organism involved in symbiotic interaction(GO:0052551) response to defense-related host nitric oxide production(GO:0052565) |
0.1 | 1.1 | GO:0051639 | actin filament network formation(GO:0051639) |
0.1 | 1.1 | GO:0030150 | protein import into mitochondrial matrix(GO:0030150) |
0.1 | 1.1 | GO:0051775 | response to redox state(GO:0051775) |
0.0 | 1.1 | GO:0060216 | definitive hemopoiesis(GO:0060216) |
Gene overrepresentation in cellular_component category:
Showing 1 to 20 of 36 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 4.2 | GO:0001533 | cornified envelope(GO:0001533) |
0.1 | 2.9 | GO:0033268 | node of Ranvier(GO:0033268) |
0.1 | 2.0 | GO:0005685 | U1 snRNP(GO:0005685) |
0.0 | 1.7 | GO:0005790 | smooth endoplasmic reticulum(GO:0005790) |
0.1 | 1.4 | GO:0001741 | XY body(GO:0001741) |
0.0 | 1.4 | GO:0008180 | COP9 signalosome(GO:0008180) |
0.1 | 1.1 | GO:0005744 | mitochondrial inner membrane presequence translocase complex(GO:0005744) |
0.0 | 1.1 | GO:0043205 | microfibril(GO:0001527) fibril(GO:0043205) |
0.0 | 1.1 | GO:0001891 | phagocytic cup(GO:0001891) |
0.0 | 1.1 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
0.1 | 1.0 | GO:0031232 | extrinsic component of external side of plasma membrane(GO:0031232) |
0.0 | 1.0 | GO:0016328 | lateral plasma membrane(GO:0016328) |
0.0 | 0.9 | GO:0042571 | immunoglobulin complex, circulating(GO:0042571) |
0.2 | 0.8 | GO:0005602 | complement component C1 complex(GO:0005602) |
0.1 | 0.8 | GO:0071144 | SMAD2-SMAD3 protein complex(GO:0071144) |
0.1 | 0.8 | GO:0030478 | actin cap(GO:0030478) |
0.2 | 0.7 | GO:0097442 | CA3 pyramidal cell dendrite(GO:0097442) |
0.1 | 0.7 | GO:0033503 | HULC complex(GO:0033503) |
0.1 | 0.7 | GO:0097169 | AIM2 inflammasome complex(GO:0097169) |
0.1 | 0.7 | GO:0033093 | Weibel-Palade body(GO:0033093) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 70 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 4.3 | GO:0008307 | structural constituent of muscle(GO:0008307) |
0.5 | 3.3 | GO:0047045 | testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045) |
0.1 | 2.9 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
0.0 | 2.8 | GO:0004984 | olfactory receptor activity(GO:0004984) |
0.1 | 2.7 | GO:0008327 | methyl-CpG binding(GO:0008327) |
0.3 | 2.2 | GO:0004499 | N,N-dimethylaniline monooxygenase activity(GO:0004499) |
0.3 | 2.1 | GO:0035614 | snRNA stem-loop binding(GO:0035614) |
0.4 | 1.8 | GO:0030395 | lactose binding(GO:0030395) |
0.0 | 1.8 | GO:0051879 | Hsp90 protein binding(GO:0051879) |
0.2 | 1.6 | GO:0005134 | interleukin-2 receptor binding(GO:0005134) |
0.0 | 1.6 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
0.1 | 1.4 | GO:0033038 | bitter taste receptor activity(GO:0033038) |
0.1 | 1.4 | GO:0005001 | transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198) |
0.0 | 1.3 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
0.1 | 1.1 | GO:0004065 | arylsulfatase activity(GO:0004065) |
0.0 | 1.1 | GO:0004383 | guanylate cyclase activity(GO:0004383) |
0.0 | 1.1 | GO:0034987 | immunoglobulin receptor binding(GO:0034987) |
0.3 | 1.0 | GO:0015091 | ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510) |
0.0 | 1.0 | GO:0038191 | neuropilin binding(GO:0038191) |
0.3 | 0.9 | GO:0017095 | heparan sulfate 6-O-sulfotransferase activity(GO:0017095) |
Gene overrepresentation in C2:CP category:
Showing 1 to 12 of 12 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 3.5 | NABA_ECM_AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
0.0 | 2.9 | NABA_PROTEOGLYCANS | Genes encoding proteoglycans |
0.0 | 1.1 | PID_CIRCADIAN_PATHWAY | Circadian rhythm pathway |
0.0 | 1.1 | PID_NOTCH_PATHWAY | Notch signaling pathway |
0.0 | 1.0 | PID_IL2_STAT5_PATHWAY | IL2 signaling events mediated by STAT5 |
0.0 | 1.0 | PID_EPHB_FWD_PATHWAY | EPHB forward signaling |
0.0 | 1.0 | PID_KIT_PATHWAY | Signaling events mediated by Stem cell factor receptor (c-Kit) |
0.0 | 0.9 | PID_FANCONI_PATHWAY | Fanconi anemia pathway |
0.0 | 0.8 | PID_SMAD2_3PATHWAY | Regulation of cytoplasmic and nuclear SMAD2/3 signaling |
0.0 | 0.7 | PID_MAPK_TRK_PATHWAY | Trk receptor signaling mediated by the MAPK pathway |
0.0 | 0.6 | PID_CXCR3_PATHWAY | CXCR3-mediated signaling events |
0.0 | 0.6 | SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES | Genes related to regulation of the actin cytoskeleton |
Gene overrepresentation in C2:CP:REACTOME category:
Showing 1 to 20 of 25 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 3.3 | REACTOME_ANDROGEN_BIOSYNTHESIS | Genes involved in Androgen biosynthesis |
0.0 | 2.8 | REACTOME_OLFACTORY_SIGNALING_PATHWAY | Genes involved in Olfactory Signaling Pathway |
0.0 | 2.2 | REACTOME_PHASE1_FUNCTIONALIZATION_OF_COMPOUNDS | Genes involved in Phase 1 - Functionalization of compounds |
0.0 | 2.0 | REACTOME_MRNA_SPLICING | Genes involved in mRNA Splicing |
0.1 | 1.4 | REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES | Genes involved in The activation of arylsulfatases |
0.0 | 1.1 | REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA | Genes involved in Circadian Repression of Expression by REV-ERBA |
0.0 | 1.1 | REACTOME_NITRIC_OXIDE_STIMULATES_GUANYLATE_CYCLASE | Genes involved in Nitric oxide stimulates guanylate cyclase |
0.0 | 1.1 | REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT | Genes involved in Mitochondrial Protein Import |
0.0 | 0.9 | REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS | Genes involved in Homologous recombination repair of replication-independent double-strand breaks |
0.0 | 0.9 | REACTOME_TRANSFERRIN_ENDOCYTOSIS_AND_RECYCLING | Genes involved in Transferrin endocytosis and recycling |
0.0 | 0.9 | REACTOME_HS_GAG_BIOSYNTHESIS | Genes involved in HS-GAG biosynthesis |
0.1 | 0.8 | REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS | Genes involved in Creation of C4 and C2 activators |
0.0 | 0.8 | REACTOME_SIGNALING_BY_NODAL | Genes involved in Signaling by NODAL |
0.0 | 0.8 | REACTOME_SMOOTH_MUSCLE_CONTRACTION | Genes involved in Smooth Muscle Contraction |
0.0 | 0.7 | REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS | Genes involved in Facilitative Na+-independent glucose transporters |
0.0 | 0.7 | REACTOME_SIGNALLING_TO_P38_VIA_RIT_AND_RIN | Genes involved in Signalling to p38 via RIT and RIN |
0.0 | 0.7 | REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING | Genes involved in Insulin Synthesis and Processing |
0.0 | 0.6 | REACTOME_SLBP_DEPENDENT_PROCESSING_OF_REPLICATION_DEPENDENT_HISTONE_PRE_MRNAS | Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs |
0.0 | 0.6 | REACTOME_DARPP_32_EVENTS | Genes involved in DARPP-32 events |
0.0 | 0.5 | REACTOME_GLUCURONIDATION | Genes involved in Glucuronidation |