Motif ID: SOX30

Z-value: 0.379


Transcription factors associated with SOX30:

Gene SymbolEntrez IDGene Name
SOX30 ENSG00000039600.6 SOX30

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
SOX30hg19_v2_chr5_-_157079428_157079452,
hg19_v2_chr5_-_157079372_157079395		-0.213.2e-01Click!


Activity profile for motif SOX30.

activity profile for motif SOX30


Sorted Z-values histogram for motif SOX30

Sorted Z-values for motif SOX30



Network of associatons between targets according to the STRING database.



First level regulatory network of SOX30

PNG image of the network

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Top targets:


Showing 1 to 20 of 110 entries
PromoterScoreRefseqGene SymbolGene Name
chr10_-_28270795 1.472 ENST00000545014.1
 ARMC4
armadillo repeat containing 4
chr3_-_19988462 1.064 ENST00000344838.4
 EFHB
EF-hand domain family, member B
chr6_+_131958436 1.009 ENST00000357639.3
ENST00000543135.1
ENST00000427148.2
ENST00000358229.5
 ENPP3



ectonucleotide pyrophosphatase/phosphodiesterase 3



chr1_+_47489240 0.959 ENST00000371901.3
 CYP4X1
cytochrome P450, family 4, subfamily X, polypeptide 1
chr6_-_139613269 0.868 ENST00000358430.3
 TXLNB
taxilin beta
chr12_-_10282836 0.840 ENST00000304084.8
ENST00000353231.5
ENST00000525605.1
 CLEC7A


C-type lectin domain family 7, member A


chr3_+_181429704 0.596 ENST00000431565.2
ENST00000325404.1
 SOX2

SRY (sex determining region Y)-box 2

chr4_-_70725856 0.573 ENST00000226444.3
 SULT1E1
sulfotransferase family 1E, estrogen-preferring, member 1
chr4_+_77356248 0.514 ENST00000296043.6
 SHROOM3
shroom family member 3
chr8_+_24151553 0.486 ENST00000265769.4
ENST00000540823.1
ENST00000397649.3
 ADAM28


ADAM metallopeptidase domain 28


chr5_-_160279207 0.457 ENST00000327245.5
 ATP10B
ATPase, class V, type 10B
chr6_-_134639180 0.447 ENST00000367858.5
 SGK1
serum/glucocorticoid regulated kinase 1
chr11_-_75236867 0.422 ENST00000376282.3
ENST00000336898.3
 GDPD5

glycerophosphodiester phosphodiesterase domain containing 5

chr8_+_105352050 0.418 ENST00000297581.2
 DCSTAMP
dendrocyte expressed seven transmembrane protein
chr5_+_140235469 0.414 ENST00000506939.2
ENST00000307360.5
 PCDHA10

protocadherin alpha 10

chr12_-_10282742 0.398 ENST00000298523.5
ENST00000396484.2
ENST00000310002.4
 CLEC7A


C-type lectin domain family 7, member A


chr12_-_10282681 0.394 ENST00000533022.1
 CLEC7A
C-type lectin domain family 7, member A
chr2_+_232573208 0.355 ENST00000409115.3
 PTMA
prothymosin, alpha
chr10_+_35415851 0.346 ENST00000374726.3
 CREM
cAMP responsive element modulator
chr10_+_70480963 0.344 ENST00000265872.6
ENST00000535016.1
ENST00000538031.1
ENST00000543719.1
ENST00000539539.1
ENST00000543225.1
ENST00000536012.1
ENST00000494903.2
 CCAR1







cell division cycle and apoptosis regulator 1








Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 27 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.6 GO:0009756 carbohydrate mediated signaling(GO:0009756)
0.1 1.5 GO:0003356 regulation of cilium beat frequency(GO:0003356)
0.3 1.0 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.1 0.8 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.2 0.6 GO:0006711 estrogen catabolic process(GO:0006711)
0.1 0.6 GO:0001714 endodermal cell fate specification(GO:0001714)
0.0 0.5 GO:0045332 phospholipid translocation(GO:0045332)
0.1 0.4 GO:0034239 macrophage fusion(GO:0034238) regulation of macrophage fusion(GO:0034239) positive regulation of macrophage fusion(GO:0034241)
0.0 0.4 GO:0070294 renal sodium ion absorption(GO:0070294)
0.0 0.4 GO:0048505 regulation of development, heterochronic(GO:0040034) regulation of timing of cell differentiation(GO:0048505)
0.0 0.4 GO:0045176 apical protein localization(GO:0045176)
0.1 0.3 GO:0021986 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.0 0.3 GO:0015747 urate transport(GO:0015747)
0.1 0.2 GO:0051758 homologous chromosome movement towards spindle pole involved in homologous chromosome segregation(GO:0051758)
0.0 0.2 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.2 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.2 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.2 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.1 GO:0014016 neuroblast differentiation(GO:0014016)
0.0 0.1 GO:0048203 vesicle targeting, trans-Golgi to endosome(GO:0048203)

Gene overrepresentation in cellular_component category:

Showing 1 to 2 of 2 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.5 GO:0097546 ciliary base(GO:0097546)
0.0 0.6 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 20 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.6 GO:0008329 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.2 1.0 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.0 1.0 GO:0070330 aromatase activity(GO:0070330)
0.0 0.8 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 0.6 GO:0050294 flavonol 3-sulfotransferase activity(GO:0047894) steroid sulfotransferase activity(GO:0050294)
0.0 0.6 GO:0035198 miRNA binding(GO:0035198)
0.0 0.5 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.5 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 0.4 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.0 0.4 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.3 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.3 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.2 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 0.2 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.2 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.1 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.0 0.1 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.0 0.1 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.0 0.1 GO:0016403 dimethylargininase activity(GO:0016403)
0.0 0.1 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 2 of 2 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.6 REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.2 REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS Genes involved in Activation of the AP-1 family of transcription factors