Motif ID: STAT1_STAT3_BCL6
Z-value: 1.366
Transcription factors associated with STAT1_STAT3_BCL6:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| BCL6 | ENSG00000113916.13 | BCL6 |
| STAT1 | ENSG00000115415.14 | STAT1 |
| STAT3 | ENSG00000168610.10 | STAT3 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| BCL6 | hg19_v2_chr3_-_187454281_187454357 | -0.32 | 1.3e-01 | Click! |
| STAT3 | hg19_v2_chr17_-_40540377_40540481 | -0.15 | 5.0e-01 | Click! |
| STAT1 | hg19_v2_chr2_-_191878874_191878976 | 0.12 | 5.7e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.1 | 3.2 | GO:0006154 | adenosine catabolic process(GO:0006154) inosine biosynthetic process(GO:0046103) |
| 0.9 | 3.6 | GO:0038123 | toll-like receptor TLR1:TLR2 signaling pathway(GO:0038123) response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727) |
| 0.8 | 3.9 | GO:0014835 | myoblast differentiation involved in skeletal muscle regeneration(GO:0014835) |
| 0.8 | 3.0 | GO:0060708 | spongiotrophoblast differentiation(GO:0060708) |
| 0.7 | 2.1 | GO:1903225 | negative regulation of endodermal cell differentiation(GO:1903225) |
| 0.7 | 2.7 | GO:0097368 | establishment of Sertoli cell barrier(GO:0097368) |
| 0.6 | 1.9 | GO:0006500 | N-terminal protein palmitoylation(GO:0006500) |
| 0.5 | 1.4 | GO:0048597 | B cell negative selection(GO:0002352) post-embryonic camera-type eye morphogenesis(GO:0048597) |
| 0.4 | 2.1 | GO:0006436 | tryptophanyl-tRNA aminoacylation(GO:0006436) |
| 0.4 | 5.7 | GO:0015816 | glycine transport(GO:0015816) |
| 0.4 | 1.9 | GO:1902378 | vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040) |
| 0.4 | 1.1 | GO:0046521 | sphingoid catabolic process(GO:0046521) |
| 0.4 | 2.5 | GO:0051639 | actin filament network formation(GO:0051639) |
| 0.4 | 1.1 | GO:2000196 | positive regulation of female gonad development(GO:2000196) |
| 0.3 | 1.4 | GO:0006435 | threonyl-tRNA aminoacylation(GO:0006435) |
| 0.3 | 1.3 | GO:1903984 | positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984) |
| 0.3 | 1.6 | GO:0032929 | negative regulation of superoxide anion generation(GO:0032929) |
| 0.3 | 2.8 | GO:0072144 | glomerular mesangial cell development(GO:0072144) |
| 0.3 | 1.8 | GO:0038165 | oncostatin-M-mediated signaling pathway(GO:0038165) |
| 0.3 | 2.7 | GO:0035502 | metanephric part of ureteric bud development(GO:0035502) |
| 0.3 | 0.3 | GO:0032264 | IMP salvage(GO:0032264) |
| 0.3 | 2.0 | GO:0003065 | positive regulation of heart rate by epinephrine(GO:0003065) |
| 0.2 | 1.0 | GO:0046035 | CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035) |
| 0.2 | 2.4 | GO:0030951 | establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951) |
| 0.2 | 0.7 | GO:1902910 | regulation of monophenol monooxygenase activity(GO:0032771) positive regulation of monophenol monooxygenase activity(GO:0032773) negative regulation of catagen(GO:0051796) regulation of hair cycle by canonical Wnt signaling pathway(GO:0060901) positive regulation of melanosome transport(GO:1902910) |
| 0.2 | 0.9 | GO:1905167 | receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport(GO:0090118) positive regulation of lysosomal protein catabolic process(GO:1905167) |
| 0.2 | 2.5 | GO:0060753 | regulation of mast cell chemotaxis(GO:0060753) |
| 0.2 | 0.7 | GO:0032764 | negative regulation of mast cell cytokine production(GO:0032764) |
| 0.2 | 0.7 | GO:0045629 | negative regulation of T-helper 2 cell differentiation(GO:0045629) |
| 0.2 | 0.7 | GO:0002277 | myeloid dendritic cell activation involved in immune response(GO:0002277) |
| 0.2 | 1.9 | GO:2000253 | positive regulation of feeding behavior(GO:2000253) |
| 0.2 | 1.1 | GO:0060447 | bud outgrowth involved in lung branching(GO:0060447) |
| 0.2 | 0.6 | GO:0090425 | hepatocyte cell migration(GO:0002194) otic placode formation(GO:0043049) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979) |
| 0.2 | 1.1 | GO:0048850 | hypophysis morphogenesis(GO:0048850) |
| 0.2 | 0.8 | GO:0046125 | thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125) |
| 0.2 | 2.7 | GO:0044351 | macropinocytosis(GO:0044351) |
| 0.2 | 1.7 | GO:0051549 | positive regulation of keratinocyte migration(GO:0051549) positive regulation of receptor binding(GO:1900122) |
| 0.2 | 1.0 | GO:0045918 | negative regulation of cytolysis(GO:0045918) |
| 0.2 | 1.6 | GO:0006689 | ganglioside catabolic process(GO:0006689) |
| 0.2 | 3.7 | GO:0040015 | negative regulation of multicellular organism growth(GO:0040015) |
| 0.2 | 1.8 | GO:0048711 | positive regulation of astrocyte differentiation(GO:0048711) |
| 0.2 | 1.0 | GO:0033031 | positive regulation of neutrophil apoptotic process(GO:0033031) |
| 0.2 | 1.3 | GO:0010032 | meiotic chromosome condensation(GO:0010032) |
| 0.2 | 0.7 | GO:0044111 | development involved in symbiotic interaction(GO:0044111) |
| 0.2 | 0.8 | GO:0033384 | geranyl diphosphate metabolic process(GO:0033383) geranyl diphosphate biosynthetic process(GO:0033384) farnesyl diphosphate biosynthetic process(GO:0045337) |
| 0.2 | 0.2 | GO:1990641 | response to iron ion starvation(GO:1990641) |
| 0.2 | 0.6 | GO:0046967 | cytosol to ER transport(GO:0046967) |
| 0.2 | 0.5 | GO:0032824 | natural killer cell differentiation involved in immune response(GO:0002325) negative regulation of natural killer cell differentiation(GO:0032824) regulation of natural killer cell differentiation involved in immune response(GO:0032826) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827) |
| 0.2 | 0.5 | GO:0080154 | regulation of fertilization(GO:0080154) |
| 0.2 | 3.6 | GO:0051764 | actin crosslink formation(GO:0051764) |
| 0.1 | 0.6 | GO:0089700 | protein kinase D signaling(GO:0089700) |
| 0.1 | 1.3 | GO:2001300 | lipoxin metabolic process(GO:2001300) |
| 0.1 | 1.1 | GO:0036072 | intramembranous ossification(GO:0001957) direct ossification(GO:0036072) |
| 0.1 | 1.3 | GO:1903027 | regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959) regulation of opsonization(GO:1903027) |
| 0.1 | 0.5 | GO:0001188 | RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189) |
| 0.1 | 0.5 | GO:0000711 | meiotic DNA repair synthesis(GO:0000711) |
| 0.1 | 0.6 | GO:0055014 | atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014) |
| 0.1 | 0.5 | GO:0050928 | negative regulation of positive chemotaxis(GO:0050928) |
| 0.1 | 0.4 | GO:0002605 | negative regulation of dendritic cell antigen processing and presentation(GO:0002605) regulation of cytotoxic T cell degranulation(GO:0043317) negative regulation of cytotoxic T cell degranulation(GO:0043318) |
| 0.1 | 0.4 | GO:0016094 | polyprenol biosynthetic process(GO:0016094) |
| 0.1 | 0.4 | GO:0060474 | positive regulation of sperm motility involved in capacitation(GO:0060474) |
| 0.1 | 0.6 | GO:2001288 | positive regulation of caveolin-mediated endocytosis(GO:2001288) |
| 0.1 | 0.5 | GO:0042796 | snRNA transcription from RNA polymerase III promoter(GO:0042796) |
| 0.1 | 0.7 | GO:0060480 | lung goblet cell differentiation(GO:0060480) |
| 0.1 | 0.3 | GO:0001544 | initiation of primordial ovarian follicle growth(GO:0001544) |
| 0.1 | 1.9 | GO:0006703 | estrogen biosynthetic process(GO:0006703) |
| 0.1 | 1.6 | GO:0010739 | positive regulation of protein kinase A signaling(GO:0010739) |
| 0.1 | 1.1 | GO:0051694 | pointed-end actin filament capping(GO:0051694) |
| 0.1 | 0.5 | GO:0060574 | intestinal epithelial cell maturation(GO:0060574) |
| 0.1 | 0.9 | GO:2000852 | corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852) |
| 0.1 | 0.8 | GO:0034128 | negative regulation of MyD88-independent toll-like receptor signaling pathway(GO:0034128) |
| 0.1 | 0.8 | GO:2000467 | positive regulation of glycogen (starch) synthase activity(GO:2000467) |
| 0.1 | 0.3 | GO:0098968 | neurotransmitter receptor transport postsynaptic membrane to endosome(GO:0098968) |
| 0.1 | 0.3 | GO:0031247 | actin rod assembly(GO:0031247) |
| 0.1 | 0.3 | GO:0015817 | histidine transport(GO:0015817) L-histidine transmembrane transport(GO:0089709) L-histidine transport(GO:1902024) |
| 0.1 | 0.3 | GO:0007412 | axon target recognition(GO:0007412) |
| 0.1 | 1.3 | GO:0030321 | transepithelial chloride transport(GO:0030321) |
| 0.1 | 0.3 | GO:2000110 | negative regulation of macrophage apoptotic process(GO:2000110) |
| 0.1 | 0.4 | GO:0071469 | detection of mechanical stimulus involved in sensory perception of touch(GO:0050976) cellular response to alkaline pH(GO:0071469) |
| 0.1 | 0.3 | GO:2000910 | negative regulation of cholesterol import(GO:0060621) negative regulation of sterol import(GO:2000910) |
| 0.1 | 0.8 | GO:0007217 | tachykinin receptor signaling pathway(GO:0007217) |
| 0.1 | 0.3 | GO:0002728 | negative regulation of natural killer cell cytokine production(GO:0002728) |
| 0.1 | 0.4 | GO:0007402 | ganglion mother cell fate determination(GO:0007402) |
| 0.1 | 0.9 | GO:0048752 | semicircular canal morphogenesis(GO:0048752) |
| 0.1 | 4.1 | GO:0006607 | NLS-bearing protein import into nucleus(GO:0006607) |
| 0.1 | 0.1 | GO:0014839 | myoblast migration involved in skeletal muscle regeneration(GO:0014839) |
| 0.1 | 0.7 | GO:0021842 | directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) |
| 0.1 | 0.2 | GO:0050720 | interleukin-1 beta biosynthetic process(GO:0050720) |
| 0.1 | 0.4 | GO:0071484 | response to high light intensity(GO:0009644) cellular response to light intensity(GO:0071484) |
| 0.1 | 0.3 | GO:2000296 | negative regulation of hydrogen peroxide catabolic process(GO:2000296) |
| 0.1 | 1.3 | GO:1904778 | regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778) |
| 0.1 | 0.4 | GO:0045590 | negative regulation of regulatory T cell differentiation(GO:0045590) |
| 0.1 | 3.2 | GO:0032461 | positive regulation of protein oligomerization(GO:0032461) |
| 0.1 | 3.3 | GO:0007205 | protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205) |
| 0.1 | 0.2 | GO:0050855 | regulation of B cell receptor signaling pathway(GO:0050855) |
| 0.1 | 0.7 | GO:0038060 | nitric oxide-cGMP-mediated signaling pathway(GO:0038060) |
| 0.1 | 0.3 | GO:0035482 | negative regulation of sodium:proton antiporter activity(GO:0032416) gastric motility(GO:0035482) gastric emptying(GO:0035483) musculoskeletal movement, spinal reflex action(GO:0050883) |
| 0.1 | 0.5 | GO:0021562 | vestibulocochlear nerve development(GO:0021562) |
| 0.1 | 0.3 | GO:0009298 | GDP-mannose biosynthetic process(GO:0009298) |
| 0.1 | 0.8 | GO:0043152 | induction of bacterial agglutination(GO:0043152) |
| 0.1 | 0.6 | GO:0000727 | double-strand break repair via break-induced replication(GO:0000727) |
| 0.1 | 0.5 | GO:0097338 | response to clozapine(GO:0097338) |
| 0.1 | 1.0 | GO:0071397 | cellular response to cholesterol(GO:0071397) |
| 0.1 | 1.5 | GO:0030277 | maintenance of gastrointestinal epithelium(GO:0030277) |
| 0.1 | 0.9 | GO:0033623 | regulation of integrin activation(GO:0033623) |
| 0.1 | 0.2 | GO:0016561 | protein import into peroxisome matrix, translocation(GO:0016561) |
| 0.1 | 0.2 | GO:0051685 | maintenance of ER location(GO:0051685) |
| 0.1 | 0.4 | GO:0000720 | pyrimidine dimer repair by nucleotide-excision repair(GO:0000720) |
| 0.1 | 0.3 | GO:0044211 | CTP salvage(GO:0044211) |
| 0.1 | 1.6 | GO:0007172 | signal complex assembly(GO:0007172) |
| 0.1 | 1.2 | GO:0046415 | urate metabolic process(GO:0046415) |
| 0.1 | 0.4 | GO:0045218 | zonula adherens maintenance(GO:0045218) |
| 0.1 | 3.6 | GO:0007520 | myoblast fusion(GO:0007520) |
| 0.1 | 0.3 | GO:1904647 | response to rotenone(GO:1904647) |
| 0.1 | 0.3 | GO:0032625 | interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619) |
| 0.1 | 0.3 | GO:0009253 | peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253) |
| 0.1 | 0.2 | GO:1903978 | regulation of microglial cell activation(GO:1903978) |
| 0.1 | 0.3 | GO:0046462 | monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651) |
| 0.1 | 0.5 | GO:2000189 | positive regulation of cholesterol homeostasis(GO:2000189) |
| 0.1 | 0.3 | GO:1903300 | negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300) |
| 0.1 | 0.3 | GO:0030070 | insulin processing(GO:0030070) |
| 0.1 | 0.2 | GO:0018242 | protein O-linked glycosylation via serine(GO:0018242) |
| 0.1 | 0.1 | GO:0035262 | gonad morphogenesis(GO:0035262) |
| 0.1 | 0.9 | GO:0000768 | syncytium formation by plasma membrane fusion(GO:0000768) |
| 0.1 | 0.3 | GO:0015862 | uridine transport(GO:0015862) |
| 0.1 | 0.5 | GO:0010724 | regulation of definitive erythrocyte differentiation(GO:0010724) |
| 0.1 | 0.2 | GO:2001245 | regulation of phosphatidylcholine biosynthetic process(GO:2001245) |
| 0.1 | 0.8 | GO:0006975 | DNA damage induced protein phosphorylation(GO:0006975) |
| 0.1 | 1.0 | GO:0018298 | protein-chromophore linkage(GO:0018298) |
| 0.1 | 0.5 | GO:0045916 | negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258) |
| 0.1 | 0.4 | GO:0002329 | pre-B cell differentiation(GO:0002329) |
| 0.1 | 0.1 | GO:0032242 | regulation of nucleoside transport(GO:0032242) |
| 0.1 | 0.7 | GO:0036066 | protein O-linked fucosylation(GO:0036066) |
| 0.1 | 0.5 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
| 0.1 | 0.3 | GO:2000639 | regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639) |
| 0.0 | 0.3 | GO:0051684 | maintenance of Golgi location(GO:0051684) |
| 0.0 | 0.1 | GO:0046013 | T cell homeostatic proliferation(GO:0001777) regulation of T cell homeostatic proliferation(GO:0046013) |
| 0.0 | 0.1 | GO:0044376 | RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022) |
| 0.0 | 0.2 | GO:0019075 | virus maturation(GO:0019075) |
| 0.0 | 0.3 | GO:0031022 | nuclear migration along microfilament(GO:0031022) |
| 0.0 | 0.2 | GO:0002408 | myeloid dendritic cell chemotaxis(GO:0002408) |
| 0.0 | 0.1 | GO:0007538 | primary sex determination(GO:0007538) |
| 0.0 | 0.6 | GO:1900747 | negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747) |
| 0.0 | 0.2 | GO:0001757 | somite specification(GO:0001757) |
| 0.0 | 0.2 | GO:0006883 | cellular sodium ion homeostasis(GO:0006883) |
| 0.0 | 0.4 | GO:0061302 | smooth muscle cell-matrix adhesion(GO:0061302) |
| 0.0 | 0.2 | GO:2000346 | negative regulation of hepatocyte proliferation(GO:2000346) |
| 0.0 | 0.2 | GO:0032483 | regulation of Rab protein signal transduction(GO:0032483) |
| 0.0 | 1.0 | GO:0045332 | phospholipid translocation(GO:0045332) |
| 0.0 | 0.2 | GO:0072513 | positive regulation of secondary heart field cardioblast proliferation(GO:0072513) |
| 0.0 | 1.9 | GO:0051602 | response to electrical stimulus(GO:0051602) |
| 0.0 | 0.4 | GO:0019532 | oxalate transport(GO:0019532) |
| 0.0 | 0.6 | GO:0030388 | fructose 1,6-bisphosphate metabolic process(GO:0030388) |
| 0.0 | 0.3 | GO:0019227 | neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870) |
| 0.0 | 0.3 | GO:0007598 | blood coagulation, extrinsic pathway(GO:0007598) |
| 0.0 | 0.2 | GO:0061737 | leukotriene signaling pathway(GO:0061737) |
| 0.0 | 0.4 | GO:0016576 | histone dephosphorylation(GO:0016576) |
| 0.0 | 0.2 | GO:0043950 | positive regulation of cAMP-mediated signaling(GO:0043950) |
| 0.0 | 0.2 | GO:2000418 | positive regulation of eosinophil migration(GO:2000418) |
| 0.0 | 0.4 | GO:0099612 | protein localization to axon(GO:0099612) |
| 0.0 | 0.7 | GO:0007213 | G-protein coupled acetylcholine receptor signaling pathway(GO:0007213) |
| 0.0 | 0.2 | GO:0033615 | mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615) |
| 0.0 | 0.1 | GO:1901842 | negative regulation of high voltage-gated calcium channel activity(GO:1901842) |
| 0.0 | 0.3 | GO:0070914 | UV-damage excision repair(GO:0070914) |
| 0.0 | 0.2 | GO:0061198 | fungiform papilla formation(GO:0061198) |
| 0.0 | 0.3 | GO:2000622 | regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623) |
| 0.0 | 0.1 | GO:0046968 | peptide antigen transport(GO:0046968) |
| 0.0 | 0.6 | GO:0051775 | response to redox state(GO:0051775) |
| 0.0 | 0.1 | GO:1901253 | negative regulation of intracellular transport of viral material(GO:1901253) |
| 0.0 | 0.2 | GO:0006848 | pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475) |
| 0.0 | 0.5 | GO:0060707 | trophoblast giant cell differentiation(GO:0060707) |
| 0.0 | 0.1 | GO:0090156 | cellular sphingolipid homeostasis(GO:0090156) |
| 0.0 | 0.1 | GO:0034140 | negative regulation of toll-like receptor 3 signaling pathway(GO:0034140) |
| 0.0 | 0.3 | GO:1903265 | positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265) |
| 0.0 | 1.1 | GO:0070207 | protein homotrimerization(GO:0070207) |
| 0.0 | 0.2 | GO:0097646 | dimeric G-protein coupled receptor signaling pathway(GO:0038042) calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647) |
| 0.0 | 0.3 | GO:0044854 | plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) caveola assembly(GO:0070836) |
| 0.0 | 0.2 | GO:0071442 | positive regulation of histone H3-K14 acetylation(GO:0071442) |
| 0.0 | 0.3 | GO:0035845 | photoreceptor cell outer segment organization(GO:0035845) |
| 0.0 | 1.0 | GO:0007176 | regulation of epidermal growth factor-activated receptor activity(GO:0007176) |
| 0.0 | 0.6 | GO:0046341 | CDP-diacylglycerol metabolic process(GO:0046341) |
| 0.0 | 0.4 | GO:0061303 | cornea development in camera-type eye(GO:0061303) |
| 0.0 | 0.4 | GO:0010839 | negative regulation of keratinocyte proliferation(GO:0010839) |
| 0.0 | 0.2 | GO:0034421 | post-translational protein acetylation(GO:0034421) |
| 0.0 | 1.3 | GO:0050690 | regulation of defense response to virus by virus(GO:0050690) |
| 0.0 | 0.3 | GO:0042492 | gamma-delta T cell differentiation(GO:0042492) |
| 0.0 | 0.5 | GO:1904355 | positive regulation of telomere capping(GO:1904355) |
| 0.0 | 0.4 | GO:0000712 | resolution of meiotic recombination intermediates(GO:0000712) |
| 0.0 | 0.1 | GO:0010025 | wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166) |
| 0.0 | 0.6 | GO:0061003 | positive regulation of dendritic spine morphogenesis(GO:0061003) |
| 0.0 | 0.2 | GO:0016127 | cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127) |
| 0.0 | 0.6 | GO:0046475 | glycerophospholipid catabolic process(GO:0046475) |
| 0.0 | 0.2 | GO:0043380 | regulation of memory T cell differentiation(GO:0043380) |
| 0.0 | 0.5 | GO:0036149 | phosphatidylinositol acyl-chain remodeling(GO:0036149) |
| 0.0 | 0.4 | GO:0050861 | positive regulation of B cell receptor signaling pathway(GO:0050861) |
| 0.0 | 0.0 | GO:0006844 | acyl carnitine transport(GO:0006844) acyl carnitine transmembrane transport(GO:1902616) |
| 0.0 | 0.1 | GO:0016185 | synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185) neurotransmitter receptor internalization(GO:0099590) |
| 0.0 | 0.1 | GO:0006269 | DNA replication, synthesis of RNA primer(GO:0006269) |
| 0.0 | 0.5 | GO:1902857 | positive regulation of nonmotile primary cilium assembly(GO:1902857) |
| 0.0 | 0.5 | GO:0030728 | ovulation(GO:0030728) |
| 0.0 | 0.2 | GO:0001878 | response to yeast(GO:0001878) |
| 0.0 | 0.5 | GO:0003215 | cardiac right ventricle morphogenesis(GO:0003215) |
| 0.0 | 0.1 | GO:0015722 | canalicular bile acid transport(GO:0015722) |
| 0.0 | 0.8 | GO:0007398 | ectoderm development(GO:0007398) |
| 0.0 | 0.2 | GO:0000395 | mRNA 5'-splice site recognition(GO:0000395) |
| 0.0 | 0.2 | GO:0031284 | positive regulation of guanylate cyclase activity(GO:0031284) |
| 0.0 | 0.6 | GO:0015813 | L-glutamate transport(GO:0015813) |
| 0.0 | 0.1 | GO:2000782 | regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) positive regulation of barbed-end actin filament capping(GO:2000814) |
| 0.0 | 0.4 | GO:0048266 | behavioral response to pain(GO:0048266) |
| 0.0 | 0.6 | GO:0051984 | positive regulation of chromosome segregation(GO:0051984) |
| 0.0 | 0.1 | GO:0007369 | gastrulation(GO:0007369) |
| 0.0 | 0.4 | GO:0071985 | multivesicular body sorting pathway(GO:0071985) |
| 0.0 | 0.3 | GO:2001275 | positive regulation of glucose import in response to insulin stimulus(GO:2001275) |
| 0.0 | 0.7 | GO:0014046 | dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059) |
| 0.0 | 0.1 | GO:0072137 | condensed mesenchymal cell proliferation(GO:0072137) |
| 0.0 | 0.8 | GO:1901385 | regulation of voltage-gated calcium channel activity(GO:1901385) |
| 0.0 | 1.7 | GO:0030521 | androgen receptor signaling pathway(GO:0030521) |
| 0.0 | 0.6 | GO:0046676 | negative regulation of insulin secretion(GO:0046676) |
| 0.0 | 0.6 | GO:0060261 | positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261) |
| 0.0 | 0.1 | GO:0090481 | pyrimidine nucleotide-sugar transmembrane transport(GO:0090481) |
| 0.0 | 0.6 | GO:0034080 | CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641) |
| 0.0 | 0.1 | GO:0001827 | inner cell mass cell fate commitment(GO:0001827) inner cell mass cellular morphogenesis(GO:0001828) |
| 0.0 | 0.3 | GO:0034116 | positive regulation of heterotypic cell-cell adhesion(GO:0034116) |
| 0.0 | 0.2 | GO:0090129 | positive regulation of synapse maturation(GO:0090129) |
| 0.0 | 0.8 | GO:0015914 | phospholipid transport(GO:0015914) |
| 0.0 | 0.6 | GO:0010880 | regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum(GO:0010880) |
| 0.0 | 0.3 | GO:0045603 | positive regulation of endothelial cell differentiation(GO:0045603) |
| 0.0 | 0.7 | GO:0071377 | cellular response to glucagon stimulus(GO:0071377) |
| 0.0 | 0.1 | GO:0035383 | acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383) |
| 0.0 | 2.7 | GO:0008361 | regulation of cell size(GO:0008361) |
| 0.0 | 0.3 | GO:0009312 | oligosaccharide biosynthetic process(GO:0009312) |
| 0.0 | 0.2 | GO:0002115 | store-operated calcium entry(GO:0002115) |
| 0.0 | 1.8 | GO:0098869 | cellular oxidant detoxification(GO:0098869) |
| 0.0 | 0.2 | GO:0090344 | negative regulation of cell aging(GO:0090344) |
| 0.0 | 0.4 | GO:0006491 | N-glycan processing(GO:0006491) |
| 0.0 | 0.0 | GO:0060620 | regulation of cholesterol import(GO:0060620) regulation of sterol import(GO:2000909) |
| 0.0 | 0.1 | GO:0001992 | regulation of systemic arterial blood pressure by vasopressin(GO:0001992) |
| 0.0 | 0.3 | GO:0010107 | potassium ion import(GO:0010107) |
| 0.0 | 0.3 | GO:0007625 | grooming behavior(GO:0007625) |
| 0.0 | 0.0 | GO:0002925 | positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925) |
| 0.0 | 0.2 | GO:0043627 | response to estrogen(GO:0043627) |
| 0.0 | 0.2 | GO:0003334 | keratinocyte development(GO:0003334) |
| 0.0 | 0.8 | GO:0035914 | skeletal muscle cell differentiation(GO:0035914) |
| 0.0 | 0.2 | GO:0046051 | UTP metabolic process(GO:0046051) |
| 0.0 | 0.6 | GO:0030212 | hyaluronan metabolic process(GO:0030212) |
| 0.0 | 5.1 | GO:0006936 | muscle contraction(GO:0006936) |
| 0.0 | 0.1 | GO:0016998 | cell wall macromolecule catabolic process(GO:0016998) |
| 0.0 | 0.1 | GO:0035754 | B cell chemotaxis(GO:0035754) |
| 0.0 | 0.7 | GO:0018149 | peptide cross-linking(GO:0018149) |
| 0.0 | 0.1 | GO:0043653 | mitochondrial fragmentation involved in apoptotic process(GO:0043653) |
| 0.0 | 0.2 | GO:0060628 | regulation of ER to Golgi vesicle-mediated transport(GO:0060628) |
| 0.0 | 0.1 | GO:0032291 | central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291) |
| 0.0 | 0.0 | GO:0090091 | positive regulation of extracellular matrix disassembly(GO:0090091) |
| 0.0 | 0.5 | GO:0035235 | ionotropic glutamate receptor signaling pathway(GO:0035235) |
| 0.0 | 0.9 | GO:0036498 | IRE1-mediated unfolded protein response(GO:0036498) |
| 0.0 | 0.1 | GO:0039536 | negative regulation of RIG-I signaling pathway(GO:0039536) |
| 0.0 | 0.6 | GO:0006910 | phagocytosis, recognition(GO:0006910) |
| 0.0 | 0.2 | GO:0033673 | negative regulation of kinase activity(GO:0033673) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.7 | 3.6 | GO:0046696 | lipopolysaccharide receptor complex(GO:0046696) |
| 0.7 | 2.1 | GO:0005588 | collagen type V trimer(GO:0005588) |
| 0.6 | 1.8 | GO:0005900 | oncostatin-M receptor complex(GO:0005900) |
| 0.6 | 1.8 | GO:0097453 | mesaxon(GO:0097453) ensheathing process(GO:1990015) |
| 0.5 | 7.1 | GO:0030478 | actin cap(GO:0030478) |
| 0.4 | 1.6 | GO:0005889 | hydrogen:potassium-exchanging ATPase complex(GO:0005889) |
| 0.3 | 0.9 | GO:1990666 | PCSK9-LDLR complex(GO:1990666) |
| 0.3 | 1.5 | GO:0002081 | outer acrosomal membrane(GO:0002081) |
| 0.3 | 1.8 | GO:0030485 | smooth muscle contractile fiber(GO:0030485) |
| 0.3 | 1.3 | GO:0098843 | postsynaptic endocytic zone(GO:0098843) |
| 0.2 | 1.9 | GO:0097443 | sorting endosome(GO:0097443) |
| 0.2 | 1.0 | GO:0005602 | complement component C1 complex(GO:0005602) |
| 0.2 | 0.5 | GO:0070557 | PCNA-p21 complex(GO:0070557) |
| 0.2 | 0.5 | GO:0005668 | RNA polymerase transcription factor SL1 complex(GO:0005668) |
| 0.2 | 1.2 | GO:0036021 | endolysosome lumen(GO:0036021) |
| 0.2 | 1.0 | GO:0070435 | Shc-EGFR complex(GO:0070435) |
| 0.1 | 2.8 | GO:0005862 | muscle thin filament tropomyosin(GO:0005862) |
| 0.1 | 0.4 | GO:0030849 | Y chromosome(GO:0000806) autosome(GO:0030849) |
| 0.1 | 1.3 | GO:0000796 | condensin complex(GO:0000796) |
| 0.1 | 0.4 | GO:0071821 | FANCM-MHF complex(GO:0071821) |
| 0.1 | 0.6 | GO:0035061 | interchromatin granule(GO:0035061) |
| 0.1 | 1.4 | GO:0097136 | Bcl-2 family protein complex(GO:0097136) |
| 0.1 | 3.6 | GO:0005865 | striated muscle thin filament(GO:0005865) |
| 0.1 | 0.3 | GO:0070939 | Dsl1p complex(GO:0070939) |
| 0.1 | 0.6 | GO:0042825 | TAP complex(GO:0042825) |
| 0.1 | 0.4 | GO:0048237 | rough endoplasmic reticulum lumen(GO:0048237) alphav-beta3 integrin-vitronectin complex(GO:0071062) |
| 0.1 | 3.0 | GO:0032839 | dendrite cytoplasm(GO:0032839) |
| 0.1 | 1.1 | GO:0005577 | fibrinogen complex(GO:0005577) |
| 0.1 | 0.2 | GO:0005873 | plus-end kinesin complex(GO:0005873) |
| 0.1 | 1.3 | GO:0008091 | spectrin(GO:0008091) |
| 0.1 | 1.5 | GO:0031089 | platelet dense granule lumen(GO:0031089) |
| 0.1 | 1.7 | GO:0005614 | interstitial matrix(GO:0005614) |
| 0.1 | 0.4 | GO:1990769 | proximal neuron projection(GO:1990769) |
| 0.1 | 0.1 | GO:1990667 | PCSK9-AnxA2 complex(GO:1990667) |
| 0.1 | 0.3 | GO:0031838 | haptoglobin-hemoglobin complex(GO:0031838) |
| 0.1 | 1.6 | GO:0005922 | connexon complex(GO:0005922) |
| 0.1 | 0.2 | GO:0032002 | interleukin-28 receptor complex(GO:0032002) |
| 0.1 | 0.4 | GO:0000110 | nucleotide-excision repair factor 1 complex(GO:0000110) |
| 0.1 | 0.3 | GO:0034750 | Scrib-APC-beta-catenin complex(GO:0034750) |
| 0.1 | 0.3 | GO:0008282 | ATP-sensitive potassium channel complex(GO:0008282) |
| 0.1 | 3.1 | GO:0031941 | filamentous actin(GO:0031941) |
| 0.1 | 0.2 | GO:0031088 | platelet dense granule membrane(GO:0031088) |
| 0.0 | 0.1 | GO:0016938 | kinesin I complex(GO:0016938) |
| 0.0 | 1.8 | GO:0035371 | microtubule plus-end(GO:0035371) |
| 0.0 | 0.1 | GO:0044609 | DBIRD complex(GO:0044609) |
| 0.0 | 0.6 | GO:0005589 | collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647) |
| 0.0 | 0.1 | GO:0033565 | ESCRT-0 complex(GO:0033565) |
| 0.0 | 2.6 | GO:0001772 | immunological synapse(GO:0001772) |
| 0.0 | 0.9 | GO:0097225 | sperm midpiece(GO:0097225) |
| 0.0 | 3.9 | GO:0005884 | actin filament(GO:0005884) |
| 0.0 | 0.3 | GO:0031465 | Cul4B-RING E3 ubiquitin ligase complex(GO:0031465) |
| 0.0 | 0.3 | GO:1990452 | Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452) |
| 0.0 | 0.3 | GO:0097169 | AIM2 inflammasome complex(GO:0097169) |
| 0.0 | 1.0 | GO:0031672 | A band(GO:0031672) |
| 0.0 | 0.4 | GO:0005915 | zonula adherens(GO:0005915) |
| 0.0 | 1.3 | GO:0030673 | axolemma(GO:0030673) |
| 0.0 | 0.5 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
| 0.0 | 0.5 | GO:0042555 | MCM complex(GO:0042555) |
| 0.0 | 0.3 | GO:0043194 | axon initial segment(GO:0043194) |
| 0.0 | 6.3 | GO:1904813 | ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813) |
| 0.0 | 0.2 | GO:0070847 | core mediator complex(GO:0070847) |
| 0.0 | 0.3 | GO:0030133 | transport vesicle(GO:0030133) |
| 0.0 | 0.6 | GO:0097342 | ripoptosome(GO:0097342) |
| 0.0 | 2.7 | GO:0043195 | terminal bouton(GO:0043195) |
| 0.0 | 0.2 | GO:1903440 | calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440) |
| 0.0 | 0.1 | GO:0005658 | alpha DNA polymerase:primase complex(GO:0005658) |
| 0.0 | 0.2 | GO:0097433 | dense body(GO:0097433) |
| 0.0 | 0.2 | GO:0045179 | apical cortex(GO:0045179) |
| 0.0 | 0.1 | GO:0035339 | SPOTS complex(GO:0035339) |
| 0.0 | 0.4 | GO:0000177 | cytoplasmic exosome (RNase complex)(GO:0000177) |
| 0.0 | 0.4 | GO:0005652 | nuclear lamina(GO:0005652) |
| 0.0 | 0.8 | GO:0016592 | mediator complex(GO:0016592) |
| 0.0 | 1.1 | GO:0045171 | intercellular bridge(GO:0045171) |
| 0.0 | 0.3 | GO:0033391 | chromatoid body(GO:0033391) |
| 0.0 | 0.5 | GO:0031105 | septin complex(GO:0031105) |
| 0.0 | 1.4 | GO:0001725 | stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517) |
| 0.0 | 0.2 | GO:0033018 | sarcoplasmic reticulum lumen(GO:0033018) |
| 0.0 | 0.3 | GO:0005885 | Arp2/3 protein complex(GO:0005885) |
| 0.0 | 0.5 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
| 0.0 | 0.3 | GO:0001518 | voltage-gated sodium channel complex(GO:0001518) |
| 0.0 | 0.1 | GO:0033553 | rDNA heterochromatin(GO:0033553) |
| 0.0 | 0.4 | GO:0005892 | acetylcholine-gated channel complex(GO:0005892) |
| 0.0 | 7.5 | GO:0015629 | actin cytoskeleton(GO:0015629) |
| 0.0 | 0.2 | GO:0000813 | ESCRT I complex(GO:0000813) |
| 0.0 | 0.3 | GO:0034993 | microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993) |
| 0.0 | 0.3 | GO:0034663 | endoplasmic reticulum chaperone complex(GO:0034663) |
| 0.0 | 0.1 | GO:0070876 | SOSS complex(GO:0070876) |
| 0.0 | 0.2 | GO:0000243 | commitment complex(GO:0000243) |
| 0.0 | 0.8 | GO:0033017 | sarcoplasmic reticulum membrane(GO:0033017) |
| 0.0 | 0.6 | GO:0000421 | autophagosome membrane(GO:0000421) |
| 0.0 | 0.2 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
| 0.0 | 0.0 | GO:0000502 | proteasome complex(GO:0000502) |
| 0.0 | 0.3 | GO:0000346 | transcription export complex(GO:0000346) |
| 0.0 | 0.1 | GO:0033269 | internode region of axon(GO:0033269) |
| 0.0 | 0.6 | GO:0042571 | immunoglobulin complex, circulating(GO:0042571) |
| 0.0 | 1.3 | GO:0005905 | clathrin-coated pit(GO:0005905) |
| 0.0 | 1.0 | GO:0045095 | keratin filament(GO:0045095) |
| 0.0 | 1.2 | GO:0005901 | caveola(GO:0005901) |
| 0.0 | 0.0 | GO:0098855 | HCN channel complex(GO:0098855) |
| 0.0 | 0.1 | GO:0016328 | lateral plasma membrane(GO:0016328) |
| 0.0 | 0.1 | GO:0008622 | epsilon DNA polymerase complex(GO:0008622) |
| 0.0 | 0.3 | GO:0005942 | phosphatidylinositol 3-kinase complex(GO:0005942) |
| 0.0 | 0.7 | GO:0001533 | cornified envelope(GO:0001533) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.8 | 4.1 | GO:0016019 | peptidoglycan receptor activity(GO:0016019) |
| 0.6 | 3.7 | GO:0008269 | JAK pathway signal transduction adaptor activity(GO:0008269) |
| 0.5 | 2.7 | GO:0005499 | vitamin D binding(GO:0005499) |
| 0.5 | 5.7 | GO:0015187 | glycine transmembrane transporter activity(GO:0015187) |
| 0.4 | 2.1 | GO:0004830 | tryptophan-tRNA ligase activity(GO:0004830) |
| 0.4 | 3.9 | GO:0051525 | NFAT protein binding(GO:0051525) |
| 0.4 | 1.8 | GO:0004924 | oncostatin-M receptor activity(GO:0004924) |
| 0.3 | 1.4 | GO:0004829 | threonine-tRNA ligase activity(GO:0004829) |
| 0.3 | 1.3 | GO:0016404 | 15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404) |
| 0.3 | 1.9 | GO:0047045 | testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045) |
| 0.3 | 3.7 | GO:0035374 | chondroitin sulfate binding(GO:0035374) |
| 0.3 | 0.8 | GO:0004797 | thymidine kinase activity(GO:0004797) |
| 0.3 | 8.3 | GO:0005523 | tropomyosin binding(GO:0005523) |
| 0.2 | 2.4 | GO:0019237 | centromeric DNA binding(GO:0019237) |
| 0.2 | 1.9 | GO:0038085 | vascular endothelial growth factor binding(GO:0038085) |
| 0.2 | 1.3 | GO:0045029 | UDP-activated nucleotide receptor activity(GO:0045029) |
| 0.2 | 0.6 | GO:0003881 | CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity(GO:0003881) |
| 0.2 | 3.2 | GO:0004000 | adenosine deaminase activity(GO:0004000) |
| 0.2 | 0.6 | GO:0004157 | dihydropyrimidinase activity(GO:0004157) |
| 0.2 | 0.5 | GO:0019912 | cyclin-dependent protein kinase activating kinase activity(GO:0019912) |
| 0.2 | 1.6 | GO:0004563 | beta-N-acetylhexosaminidase activity(GO:0004563) |
| 0.2 | 2.4 | GO:0047134 | protein-disulfide reductase activity(GO:0047134) |
| 0.2 | 1.0 | GO:0004882 | androgen receptor activity(GO:0004882) |
| 0.2 | 0.8 | GO:0004337 | dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337) |
| 0.1 | 0.4 | GO:0047696 | beta-adrenergic receptor kinase activity(GO:0047696) |
| 0.1 | 0.4 | GO:0008192 | RNA guanylyltransferase activity(GO:0008192) |
| 0.1 | 2.0 | GO:0033691 | sialic acid binding(GO:0033691) |
| 0.1 | 1.0 | GO:0048408 | epidermal growth factor binding(GO:0048408) |
| 0.1 | 2.7 | GO:0009931 | calcium-dependent protein serine/threonine kinase activity(GO:0009931) |
| 0.1 | 0.4 | GO:0098782 | mechanically-gated potassium channel activity(GO:0098782) |
| 0.1 | 2.4 | GO:0004143 | diacylglycerol kinase activity(GO:0004143) |
| 0.1 | 1.3 | GO:0042731 | PH domain binding(GO:0042731) |
| 0.1 | 0.9 | GO:0030229 | very-low-density lipoprotein particle receptor activity(GO:0030229) |
| 0.1 | 0.4 | GO:0002094 | polyprenyltransferase activity(GO:0002094) |
| 0.1 | 0.9 | GO:0070996 | type 1 melanocortin receptor binding(GO:0070996) |
| 0.1 | 1.3 | GO:0004849 | uridine kinase activity(GO:0004849) |
| 0.1 | 1.6 | GO:0008199 | ferric iron binding(GO:0008199) |
| 0.1 | 1.1 | GO:0045545 | syndecan binding(GO:0045545) |
| 0.1 | 1.1 | GO:0032190 | manganese ion transmembrane transporter activity(GO:0005384) acrosin binding(GO:0032190) |
| 0.1 | 0.3 | GO:0008281 | sulfonylurea receptor activity(GO:0008281) |
| 0.1 | 0.8 | GO:0050816 | phosphothreonine binding(GO:0050816) |
| 0.1 | 0.9 | GO:0015450 | P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450) |
| 0.1 | 0.4 | GO:0019770 | IgG receptor activity(GO:0019770) |
| 0.1 | 0.3 | GO:0008457 | beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256) |
| 0.1 | 0.6 | GO:0046979 | TAP2 binding(GO:0046979) |
| 0.1 | 1.2 | GO:0015143 | urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702) |
| 0.1 | 1.0 | GO:0048407 | platelet-derived growth factor binding(GO:0048407) |
| 0.1 | 1.3 | GO:0004971 | AMPA glutamate receptor activity(GO:0004971) |
| 0.1 | 0.3 | GO:0032093 | SAM domain binding(GO:0032093) |
| 0.1 | 0.5 | GO:0017050 | sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050) |
| 0.1 | 1.3 | GO:0008179 | adenylate cyclase binding(GO:0008179) |
| 0.1 | 0.3 | GO:0015180 | L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858) |
| 0.1 | 0.3 | GO:0031694 | alpha-2A adrenergic receptor binding(GO:0031694) |
| 0.1 | 1.1 | GO:0001206 | transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206) |
| 0.1 | 0.3 | GO:0070653 | high-density lipoprotein particle receptor binding(GO:0070653) |
| 0.1 | 1.0 | GO:0008020 | G-protein coupled photoreceptor activity(GO:0008020) |
| 0.1 | 2.3 | GO:0005184 | neuropeptide hormone activity(GO:0005184) |
| 0.1 | 0.6 | GO:0050692 | DBD domain binding(GO:0050692) |
| 0.1 | 0.4 | GO:0004699 | calcium-independent protein kinase C activity(GO:0004699) |
| 0.1 | 0.7 | GO:0005176 | ErbB-2 class receptor binding(GO:0005176) |
| 0.1 | 1.6 | GO:0017166 | vinculin binding(GO:0017166) |
| 0.1 | 0.2 | GO:0030627 | pre-mRNA 5'-splice site binding(GO:0030627) |
| 0.1 | 1.4 | GO:0051400 | BH domain binding(GO:0051400) |
| 0.1 | 0.4 | GO:1990599 | 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599) |
| 0.1 | 0.4 | GO:0005166 | neurotrophin p75 receptor binding(GO:0005166) |
| 0.1 | 0.1 | GO:0032396 | HLA-B specific inhibitory MHC class I receptor activity(GO:0030109) inhibitory MHC class I receptor activity(GO:0032396) |
| 0.1 | 0.2 | GO:0005477 | pyruvate secondary active transmembrane transporter activity(GO:0005477) |
| 0.1 | 3.9 | GO:0004712 | protein serine/threonine/tyrosine kinase activity(GO:0004712) |
| 0.1 | 0.3 | GO:1990050 | phosphatidic acid transporter activity(GO:1990050) |
| 0.1 | 0.2 | GO:0001632 | leukotriene B4 receptor activity(GO:0001632) |
| 0.1 | 0.9 | GO:0042301 | phosphate ion binding(GO:0042301) |
| 0.1 | 0.7 | GO:0004707 | MAP kinase activity(GO:0004707) |
| 0.1 | 0.6 | GO:0004332 | fructose-bisphosphate aldolase activity(GO:0004332) |
| 0.1 | 3.6 | GO:0001784 | phosphotyrosine binding(GO:0001784) |
| 0.1 | 0.2 | GO:0070538 | oleic acid binding(GO:0070538) |
| 0.1 | 7.8 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.1 | 0.6 | GO:0019871 | sodium channel inhibitor activity(GO:0019871) |
| 0.1 | 0.3 | GO:0031726 | CCR1 chemokine receptor binding(GO:0031726) |
| 0.1 | 1.4 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
| 0.0 | 0.8 | GO:0042809 | vitamin D receptor binding(GO:0042809) |
| 0.0 | 1.0 | GO:0044548 | S100 protein binding(GO:0044548) |
| 0.0 | 0.1 | GO:0017116 | single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116) |
| 0.0 | 1.7 | GO:0001968 | fibronectin binding(GO:0001968) |
| 0.0 | 0.3 | GO:0001591 | dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591) |
| 0.0 | 1.3 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
| 0.0 | 0.3 | GO:0008889 | glycerophosphodiester phosphodiesterase activity(GO:0008889) |
| 0.0 | 0.3 | GO:0030492 | hemoglobin binding(GO:0030492) |
| 0.0 | 0.8 | GO:0016493 | C-C chemokine receptor activity(GO:0016493) |
| 0.0 | 0.7 | GO:0001161 | intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213) |
| 0.0 | 0.3 | GO:0001665 | alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665) |
| 0.0 | 0.6 | GO:0008970 | phosphatidylcholine 1-acylhydrolase activity(GO:0008970) |
| 0.0 | 0.2 | GO:0048248 | CXCR3 chemokine receptor binding(GO:0048248) |
| 0.0 | 0.3 | GO:0008048 | calcium sensitive guanylate cyclase activator activity(GO:0008048) |
| 0.0 | 0.1 | GO:0005275 | amine transmembrane transporter activity(GO:0005275) |
| 0.0 | 0.4 | GO:0046790 | virion binding(GO:0046790) |
| 0.0 | 0.5 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
| 0.0 | 0.4 | GO:0016861 | intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861) |
| 0.0 | 0.4 | GO:0019531 | oxalate transmembrane transporter activity(GO:0019531) |
| 0.0 | 0.2 | GO:0046899 | nucleoside triphosphate adenylate kinase activity(GO:0046899) |
| 0.0 | 0.6 | GO:0008140 | cAMP response element binding protein binding(GO:0008140) |
| 0.0 | 0.6 | GO:0004697 | protein kinase C activity(GO:0004697) |
| 0.0 | 0.7 | GO:0031005 | filamin binding(GO:0031005) |
| 0.0 | 0.2 | GO:0031728 | CCR3 chemokine receptor binding(GO:0031728) |
| 0.0 | 0.1 | GO:0004362 | glutathione-disulfide reductase activity(GO:0004362) |
| 0.0 | 0.8 | GO:0004745 | retinol dehydrogenase activity(GO:0004745) |
| 0.0 | 0.3 | GO:0000340 | RNA 7-methylguanosine cap binding(GO:0000340) |
| 0.0 | 1.1 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
| 0.0 | 0.2 | GO:0016427 | tRNA (cytosine) methyltransferase activity(GO:0016427) |
| 0.0 | 0.2 | GO:0035614 | snRNA stem-loop binding(GO:0035614) |
| 0.0 | 0.8 | GO:0005159 | insulin-like growth factor receptor binding(GO:0005159) |
| 0.0 | 0.6 | GO:0001013 | RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164) |
| 0.0 | 2.7 | GO:0001618 | virus receptor activity(GO:0001618) |
| 0.0 | 0.3 | GO:0032036 | myosin heavy chain binding(GO:0032036) |
| 0.0 | 0.1 | GO:1904455 | ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455) |
| 0.0 | 0.4 | GO:0003796 | lysozyme activity(GO:0003796) |
| 0.0 | 0.6 | GO:0042043 | neurexin family protein binding(GO:0042043) |
| 0.0 | 0.2 | GO:0097643 | amylin receptor activity(GO:0097643) |
| 0.0 | 0.3 | GO:0015379 | potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820) |
| 0.0 | 0.2 | GO:0016494 | C-X-C chemokine receptor activity(GO:0016494) |
| 0.0 | 0.3 | GO:0019864 | IgG binding(GO:0019864) |
| 0.0 | 1.3 | GO:0001105 | RNA polymerase II transcription coactivator activity(GO:0001105) |
| 0.0 | 0.2 | GO:0048101 | calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101) |
| 0.0 | 0.8 | GO:0004622 | lysophospholipase activity(GO:0004622) |
| 0.0 | 0.7 | GO:0005251 | delayed rectifier potassium channel activity(GO:0005251) |
| 0.0 | 2.5 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.0 | 0.2 | GO:0035615 | clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748) |
| 0.0 | 0.6 | GO:0005521 | lamin binding(GO:0005521) |
| 0.0 | 2.6 | GO:0008565 | protein transporter activity(GO:0008565) |
| 0.0 | 0.2 | GO:0004468 | lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468) |
| 0.0 | 0.3 | GO:0086080 | protein binding involved in heterotypic cell-cell adhesion(GO:0086080) |
| 0.0 | 0.1 | GO:0039552 | RIG-I binding(GO:0039552) |
| 0.0 | 1.9 | GO:0008307 | structural constituent of muscle(GO:0008307) |
| 0.0 | 0.1 | GO:0044547 | DNA topoisomerase binding(GO:0044547) |
| 0.0 | 2.7 | GO:0004860 | protein kinase inhibitor activity(GO:0004860) |
| 0.0 | 0.4 | GO:0022848 | acetylcholine-gated cation channel activity(GO:0022848) |
| 0.0 | 0.4 | GO:0005528 | macrolide binding(GO:0005527) FK506 binding(GO:0005528) |
| 0.0 | 0.2 | GO:0004579 | dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579) |
| 0.0 | 2.1 | GO:0046332 | SMAD binding(GO:0046332) |
| 0.0 | 0.3 | GO:0050700 | CARD domain binding(GO:0050700) |
| 0.0 | 0.4 | GO:0005313 | L-glutamate transmembrane transporter activity(GO:0005313) acidic amino acid transmembrane transporter activity(GO:0015172) |
| 0.0 | 0.6 | GO:0001205 | transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205) |
| 0.0 | 0.1 | GO:0090599 | alpha-glucosidase activity(GO:0090599) |
| 0.0 | 0.1 | GO:0015165 | pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165) |
| 0.0 | 0.1 | GO:0098519 | nucleotide phosphatase activity, acting on free nucleotides(GO:0098519) |
| 0.0 | 0.1 | GO:0019210 | kinase inhibitor activity(GO:0019210) |
| 0.0 | 0.7 | GO:0001106 | RNA polymerase II transcription corepressor activity(GO:0001106) |
| 0.0 | 0.2 | GO:0031402 | sodium ion binding(GO:0031402) |
| 0.0 | 0.2 | GO:0001075 | transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075) |
| 0.0 | 0.5 | GO:0001102 | RNA polymerase II activating transcription factor binding(GO:0001102) |
| 0.0 | 0.2 | GO:0097109 | neuroligin family protein binding(GO:0097109) |
| 0.0 | 0.6 | GO:0034987 | immunoglobulin receptor binding(GO:0034987) |
| 0.0 | 0.2 | GO:0004185 | serine-type carboxypeptidase activity(GO:0004185) |
| 0.0 | 0.1 | GO:0003854 | 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854) |
| 0.0 | 0.1 | GO:0031802 | type 5 metabotropic glutamate receptor binding(GO:0031802) |
| 0.0 | 0.3 | GO:0005112 | Notch binding(GO:0005112) |
| 0.0 | 0.5 | GO:0004003 | ATP-dependent DNA helicase activity(GO:0004003) |
| 0.0 | 0.2 | GO:0015279 | store-operated calcium channel activity(GO:0015279) |
| 0.0 | 0.2 | GO:0031957 | very long-chain fatty acid-CoA ligase activity(GO:0031957) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 1.9 | ST_JAK_STAT_PATHWAY | Jak-STAT Pathway |
| 0.1 | 9.8 | PID_SYNDECAN_1_PATHWAY | Syndecan-1-mediated signaling events |
| 0.1 | 6.7 | PID_P38_MK2_PATHWAY | p38 signaling mediated by MAPKAP kinases |
| 0.1 | 4.4 | PID_TOLL_ENDOGENOUS_PATHWAY | Endogenous TLR signaling |
| 0.1 | 1.9 | PID_VEGF_VEGFR_PATHWAY | VEGF and VEGFR signaling network |
| 0.1 | 2.8 | PID_SYNDECAN_3_PATHWAY | Syndecan-3-mediated signaling events |
| 0.1 | 2.1 | PID_S1P_S1P1_PATHWAY | S1P1 pathway |
| 0.1 | 6.8 | PID_IL2_1PATHWAY | IL2-mediated signaling events |
| 0.1 | 3.5 | PID_INTEGRIN_A9B1_PATHWAY | Alpha9 beta1 integrin signaling events |
| 0.1 | 3.7 | PID_INTEGRIN2_PATHWAY | Beta2 integrin cell surface interactions |
| 0.1 | 1.4 | SA_PROGRAMMED_CELL_DEATH | Programmed cell death, or apoptosis, eliminates damaged or unneeded cells. |
| 0.1 | 0.9 | SA_TRKA_RECEPTOR | The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth. |
| 0.1 | 4.3 | PID_AURORA_B_PATHWAY | Aurora B signaling |
| 0.0 | 2.3 | PID_IL8_CXCR2_PATHWAY | IL8- and CXCR2-mediated signaling events |
| 0.0 | 3.6 | PID_NFAT_TFPATHWAY | Calcineurin-regulated NFAT-dependent transcription in lymphocytes |
| 0.0 | 4.0 | PID_DELTA_NP63_PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
| 0.0 | 0.7 | PID_IL3_PATHWAY | IL3-mediated signaling events |
| 0.0 | 0.7 | PID_P38_GAMMA_DELTA_PATHWAY | Signaling mediated by p38-gamma and p38-delta |
| 0.0 | 1.1 | ST_PHOSPHOINOSITIDE_3_KINASE_PATHWAY | PI3K Pathway |
| 0.0 | 0.3 | PID_IL6_7_PATHWAY | IL6-mediated signaling events |
| 0.0 | 0.7 | PID_IGF1_PATHWAY | IGF1 pathway |
| 0.0 | 2.5 | PID_P75_NTR_PATHWAY | p75(NTR)-mediated signaling |
| 0.0 | 1.0 | PID_HDAC_CLASSIII_PATHWAY | Signaling events mediated by HDAC Class III |
| 0.0 | 1.2 | PID_NCADHERIN_PATHWAY | N-cadherin signaling events |
| 0.0 | 0.5 | PID_CXCR3_PATHWAY | CXCR3-mediated signaling events |
| 0.0 | 0.2 | PID_PI3KCI_AKT_PATHWAY | Class I PI3K signaling events mediated by Akt |
| 0.0 | 0.6 | PID_CIRCADIAN_PATHWAY | Circadian rhythm pathway |
| 0.0 | 0.7 | PID_ALPHA_SYNUCLEIN_PATHWAY | Alpha-synuclein signaling |
| 0.0 | 1.6 | PID_HNF3A_PATHWAY | FOXA1 transcription factor network |
| 0.0 | 0.9 | PID_AJDISS_2PATHWAY | Posttranslational regulation of adherens junction stability and dissassembly |
| 0.0 | 1.8 | PID_PDGFRB_PATHWAY | PDGFR-beta signaling pathway |
| 0.0 | 0.7 | PID_ECADHERIN_STABILIZATION_PATHWAY | Stabilization and expansion of the E-cadherin adherens junction |
| 0.0 | 1.0 | NABA_PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.0 | 0.5 | PID_ERBB4_PATHWAY | ErbB4 signaling events |
| 0.0 | 0.7 | PID_FOXO_PATHWAY | FoxO family signaling |
| 0.0 | 1.0 | PID_REG_GR_PATHWAY | Glucocorticoid receptor regulatory network |
| 0.0 | 0.4 | SIG_PIP3_SIGNALING_IN_CARDIAC_MYOCTES | Genes related to PIP3 signaling in cardiac myocytes |
| 0.0 | 0.2 | PID_AMB2_NEUTROPHILS_PATHWAY | amb2 Integrin signaling |
| 0.0 | 0.3 | ST_ERK1_ERK2_MAPK_PATHWAY | ERK1/ERK2 MAPK Pathway |
| 0.0 | 0.4 | PID_TXA2PATHWAY | Thromboxane A2 receptor signaling |
| 0.0 | 0.3 | PID_FCER1_PATHWAY | Fc-epsilon receptor I signaling in mast cells |
| 0.0 | 0.8 | PID_TCR_PATHWAY | TCR signaling in naïve CD4+ T cells |
| 0.0 | 0.2 | SA_G1_AND_S_PHASES | Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition. |
| 0.0 | 0.5 | PID_HNF3B_PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.0 | 0.5 | PID_AR_TF_PATHWAY | Regulation of Androgen receptor activity |
| 0.0 | 0.4 | PID_HEDGEHOG_GLI_PATHWAY | Hedgehog signaling events mediated by Gli proteins |
| 0.0 | 1.2 | PID_MYC_ACTIV_PATHWAY | Validated targets of C-MYC transcriptional activation |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 4.5 | REACTOME_IKK_COMPLEX_RECRUITMENT_MEDIATED_BY_RIP1 | Genes involved in IKK complex recruitment mediated by RIP1 |
| 0.3 | 7.4 | REACTOME_P38MAPK_EVENTS | Genes involved in p38MAPK events |
| 0.2 | 6.2 | REACTOME_CRMPS_IN_SEMA3A_SIGNALING | Genes involved in CRMPs in Sema3A signaling |
| 0.2 | 7.2 | REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX | Genes involved in Degradation of the extracellular matrix |
| 0.2 | 11.6 | REACTOME_SMOOTH_MUSCLE_CONTRACTION | Genes involved in Smooth Muscle Contraction |
| 0.2 | 7.6 | REACTOME_GROWTH_HORMONE_RECEPTOR_SIGNALING | Genes involved in Growth hormone receptor signaling |
| 0.1 | 1.6 | REACTOME_TRAFFICKING_AND_PROCESSING_OF_ENDOSOMAL_TLR | Genes involved in Trafficking and processing of endosomal TLR |
| 0.1 | 3.6 | REACTOME_SIGNAL_REGULATORY_PROTEIN_SIRP_FAMILY_INTERACTIONS | Genes involved in Signal regulatory protein (SIRP) family interactions |
| 0.1 | 5.7 | REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE | Genes involved in Amino acid transport across the plasma membrane |
| 0.1 | 2.6 | REACTOME_PURINE_SALVAGE | Genes involved in Purine salvage |
| 0.1 | 3.4 | REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION | Genes involved in Cytosolic tRNA aminoacylation |
| 0.1 | 1.1 | REACTOME_GRB2_SOS_PROVIDES_LINKAGE_TO_MAPK_SIGNALING_FOR_INTERGRINS_ | Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins |
| 0.1 | 1.0 | REACTOME_SHC_MEDIATED_SIGNALLING | Genes involved in SHC-mediated signalling |
| 0.1 | 4.2 | REACTOME_RAP1_SIGNALLING | Genes involved in Rap1 signalling |
| 0.1 | 2.8 | REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS | Genes involved in Effects of PIP2 hydrolysis |
| 0.1 | 1.0 | REACTOME_OPSINS | Genes involved in Opsins |
| 0.1 | 2.8 | REACTOME_KINESINS | Genes involved in Kinesins |
| 0.1 | 1.6 | REACTOME_GAP_JUNCTION_ASSEMBLY | Genes involved in Gap junction assembly |
| 0.1 | 2.6 | REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE | Genes involved in Sema4D induced cell migration and growth-cone collapse |
| 0.1 | 1.3 | REACTOME_P2Y_RECEPTORS | Genes involved in P2Y receptors |
| 0.1 | 1.8 | REACTOME_BASIGIN_INTERACTIONS | Genes involved in Basigin interactions |
| 0.1 | 0.9 | REACTOME_ANDROGEN_BIOSYNTHESIS | Genes involved in Androgen biosynthesis |
| 0.1 | 1.2 | REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS | Genes involved in Facilitative Na+-independent glucose transporters |
| 0.1 | 0.8 | REACTOME_INTRINSIC_PATHWAY | Genes involved in Intrinsic Pathway |
| 0.0 | 0.9 | REACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_CYTOSOL | Genes involved in AKT phosphorylates targets in the cytosol |
| 0.0 | 1.8 | REACTOME_PYRIMIDINE_METABOLISM | Genes involved in Pyrimidine metabolism |
| 0.0 | 4.3 | REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS | Genes involved in Integrin cell surface interactions |
| 0.0 | 1.4 | REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS | Genes involved in Trafficking of GluR2-containing AMPA receptors |
| 0.0 | 0.2 | REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS | Genes involved in Elevation of cytosolic Ca2+ levels |
| 0.0 | 0.7 | REACTOME_SHC1_EVENTS_IN_ERBB4_SIGNALING | Genes involved in SHC1 events in ERBB4 signaling |
| 0.0 | 1.7 | REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS | Genes involved in Association of TriC/CCT with target proteins during biosynthesis |
| 0.0 | 0.8 | REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
| 0.0 | 1.1 | REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PLC_BETA | Genes involved in G beta:gamma signalling through PLC beta |
| 0.0 | 2.1 | REACTOME_NCAM1_INTERACTIONS | Genes involved in NCAM1 interactions |
| 0.0 | 0.8 | REACTOME_TIE2_SIGNALING | Genes involved in Tie2 Signaling |
| 0.0 | 0.4 | REACTOME_KERATAN_SULFATE_DEGRADATION | Genes involved in Keratan sulfate degradation |
| 0.0 | 0.8 | REACTOME_IL_RECEPTOR_SHC_SIGNALING | Genes involved in Interleukin receptor SHC signaling |
| 0.0 | 0.6 | REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS | Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors) |
| 0.0 | 0.6 | REACTOME_CS_DS_DEGRADATION | Genes involved in CS/DS degradation |
| 0.0 | 0.5 | REACTOME_UNWINDING_OF_DNA | Genes involved in Unwinding of DNA |
| 0.0 | 0.3 | REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL | Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol |
| 0.0 | 0.7 | REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT | Genes involved in Chylomicron-mediated lipid transport |
| 0.0 | 0.5 | REACTOME_ACYL_CHAIN_REMODELLING_OF_PS | Genes involved in Acyl chain remodelling of PS |
| 0.0 | 1.5 | REACTOME_GLYCOSPHINGOLIPID_METABOLISM | Genes involved in Glycosphingolipid metabolism |
| 0.0 | 0.4 | REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS | Genes involved in Presynaptic nicotinic acetylcholine receptors |
| 0.0 | 0.8 | REACTOME_CHOLESTEROL_BIOSYNTHESIS | Genes involved in Cholesterol biosynthesis |
| 0.0 | 0.7 | REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |
| 0.0 | 0.4 | REACTOME_CALNEXIN_CALRETICULIN_CYCLE | Genes involved in Calnexin/calreticulin cycle |
| 0.0 | 1.5 | REACTOME_DOWNSTREAM_SIGNAL_TRANSDUCTION | Genes involved in Downstream signal transduction |
| 0.0 | 0.6 | REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC | Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC |
| 0.0 | 1.2 | REACTOME_INTRINSIC_PATHWAY_FOR_APOPTOSIS | Genes involved in Intrinsic Pathway for Apoptosis |
| 0.0 | 0.6 | REACTOME_ACTIVATION_OF_THE_PRE_REPLICATIVE_COMPLEX | Genes involved in Activation of the pre-replicative complex |
| 0.0 | 0.7 | REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS | Genes involved in Adherens junctions interactions |
| 0.0 | 0.3 | REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS | Genes involved in Synthesis of substrates in N-glycan biosythesis |
| 0.0 | 0.7 | REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_GLUCAGON_LIKE_PEPTIDE1 | Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1 |
| 0.0 | 0.5 | REACTOME_RNA_POL_I_TRANSCRIPTION_TERMINATION | Genes involved in RNA Polymerase I Transcription Termination |
| 0.0 | 1.6 | REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS | Genes involved in Metabolism of vitamins and cofactors |
| 0.0 | 0.5 | REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_3_PROMOTER | Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter |
| 0.0 | 0.6 | REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA | Genes involved in Circadian Repression of Expression by REV-ERBA |
| 0.0 | 0.2 | REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS | Genes involved in Bile salt and organic anion SLC transporters |
| 0.0 | 0.3 | REACTOME_MTORC1_MEDIATED_SIGNALLING | Genes involved in mTORC1-mediated signalling |
| 0.0 | 0.4 | REACTOME_FORMATION_OF_INCISION_COMPLEX_IN_GG_NER | Genes involved in Formation of incision complex in GG-NER |
| 0.0 | 0.2 | REACTOME_CELL_SURFACE_INTERACTIONS_AT_THE_VASCULAR_WALL | Genes involved in Cell surface interactions at the vascular wall |
| 0.0 | 0.4 | REACTOME_CTLA4_INHIBITORY_SIGNALING | Genes involved in CTLA4 inhibitory signaling |
| 0.0 | 0.2 | REACTOME_TRAF6_MEDIATED_INDUCTION_OF_TAK1_COMPLEX | Genes involved in TRAF6 mediated induction of TAK1 complex |
| 0.0 | 1.1 | REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE | Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere |
| 0.0 | 0.2 | REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING | Genes involved in DCC mediated attractive signaling |
| 0.0 | 0.1 | REACTOME_CELL_DEATH_SIGNALLING_VIA_NRAGE_NRIF_AND_NADE | Genes involved in Cell death signalling via NRAGE, NRIF and NADE |
| 0.0 | 0.6 | REACTOME_GLYCOLYSIS | Genes involved in Glycolysis |
| 0.0 | 0.4 | REACTOME_FANCONI_ANEMIA_PATHWAY | Genes involved in Fanconi Anemia pathway |
| 0.0 | 2.6 | REACTOME_G_ALPHA_I_SIGNALLING_EVENTS | Genes involved in G alpha (i) signalling events |
| 0.0 | 0.2 | REACTOME_EICOSANOID_LIGAND_BINDING_RECEPTORS | Genes involved in Eicosanoid ligand-binding receptors |
| 0.0 | 1.4 | REACTOME_PPARA_ACTIVATES_GENE_EXPRESSION | Genes involved in PPARA Activates Gene Expression |
| 0.0 | 1.0 | REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
| 0.0 | 0.3 | REACTOME_INWARDLY_RECTIFYING_K_CHANNELS | Genes involved in Inwardly rectifying K+ channels |
| 0.0 | 0.0 | REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION_IN_TLR7_8_OR_9_SIGNALING | Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling |
| 0.0 | 1.3 | REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION | Genes involved in Factors involved in megakaryocyte development and platelet production |
| 0.0 | 0.6 | REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES | Genes involved in Ion transport by P-type ATPases |
| 0.0 | 0.2 | REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS | Genes involved in Tandem pore domain potassium channels |
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