Motif ID: TBP
Z-value: 1.745

Transcription factors associated with TBP:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
TBP | ENSG00000112592.8 | TBP |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
TBP | hg19_v2_chr6_+_170863421_170863484 | 0.24 | 2.5e-01 | Click! |
Top targets:
Showing 1 to 20 of 200 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 220 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 33.2 | GO:0070268 | cornification(GO:0070268) |
0.3 | 8.9 | GO:0001829 | trophectodermal cell differentiation(GO:0001829) |
0.2 | 7.4 | GO:0032332 | positive regulation of chondrocyte differentiation(GO:0032332) |
1.5 | 7.3 | GO:0060356 | leucine import(GO:0060356) |
0.2 | 6.8 | GO:0071294 | cellular response to zinc ion(GO:0071294) |
0.0 | 5.3 | GO:0006334 | nucleosome assembly(GO:0006334) |
0.9 | 5.2 | GO:0055064 | chloride ion homeostasis(GO:0055064) |
1.0 | 5.1 | GO:1903224 | regulation of endodermal cell differentiation(GO:1903224) |
0.2 | 4.7 | GO:0071481 | cellular response to X-ray(GO:0071481) |
1.5 | 4.6 | GO:1902299 | pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) regulation of chromatin silencing at telomere(GO:0031938) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299) |
1.5 | 4.6 | GO:0060474 | positive regulation of sperm motility involved in capacitation(GO:0060474) |
1.5 | 4.4 | GO:0018153 | isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262) |
0.3 | 4.4 | GO:0001542 | ovulation from ovarian follicle(GO:0001542) |
0.1 | 4.4 | GO:1903963 | arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963) |
1.1 | 4.3 | GO:0045065 | cytotoxic T cell differentiation(GO:0045065) |
0.2 | 4.2 | GO:0006346 | methylation-dependent chromatin silencing(GO:0006346) |
0.3 | 4.1 | GO:0002227 | innate immune response in mucosa(GO:0002227) |
1.3 | 4.0 | GO:0070512 | regulation of histone H4-K20 methylation(GO:0070510) positive regulation of histone H4-K20 methylation(GO:0070512) |
1.3 | 3.9 | GO:0042270 | protection from natural killer cell mediated cytotoxicity(GO:0042270) |
0.1 | 3.9 | GO:0006953 | acute-phase response(GO:0006953) |
Gene overrepresentation in cellular_component category:
Showing 1 to 20 of 98 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 17.8 | GO:0001533 | cornified envelope(GO:0001533) |
0.1 | 16.5 | GO:0005882 | intermediate filament(GO:0005882) |
0.2 | 11.1 | GO:0000786 | nucleosome(GO:0000786) |
0.1 | 10.9 | GO:0005604 | basement membrane(GO:0005604) |
0.0 | 7.8 | GO:0042470 | melanosome(GO:0042470) pigment granule(GO:0048770) |
0.1 | 5.6 | GO:0005790 | smooth endoplasmic reticulum(GO:0005790) |
0.0 | 5.5 | GO:0031093 | platelet alpha granule lumen(GO:0031093) |
1.5 | 4.6 | GO:0036387 | nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387) |
1.1 | 4.6 | GO:1990742 | microvesicle(GO:1990742) |
0.8 | 4.6 | GO:0097129 | cyclin D2-CDK4 complex(GO:0097129) |
0.1 | 4.3 | GO:0034364 | high-density lipoprotein particle(GO:0034364) |
0.0 | 4.2 | GO:0009898 | cytoplasmic side of plasma membrane(GO:0009898) |
1.0 | 4.0 | GO:0031436 | BRCA1-BARD1 complex(GO:0031436) |
0.5 | 3.6 | GO:0035976 | AP1 complex(GO:0035976) |
1.1 | 3.4 | GO:0009330 | DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330) |
0.1 | 3.2 | GO:0005865 | striated muscle thin filament(GO:0005865) |
1.0 | 3.0 | GO:0070762 | nuclear pore transmembrane ring(GO:0070762) |
1.0 | 3.0 | GO:0043511 | inhibin complex(GO:0043511) inhibin A complex(GO:0043512) |
0.1 | 3.0 | GO:0001772 | immunological synapse(GO:0001772) |
0.1 | 2.8 | GO:0031430 | M band(GO:0031430) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 168 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 31.2 | GO:0005198 | structural molecule activity(GO:0005198) |
0.0 | 9.0 | GO:0046982 | protein heterodimerization activity(GO:0046982) |
0.1 | 8.5 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
1.5 | 7.4 | GO:0004720 | protein-lysine 6-oxidase activity(GO:0004720) |
0.5 | 7.3 | GO:0005432 | calcium:sodium antiporter activity(GO:0005432) |
0.1 | 6.9 | GO:0003684 | damaged DNA binding(GO:0003684) |
0.3 | 5.2 | GO:0004089 | carbonate dehydratase activity(GO:0004089) |
0.0 | 5.1 | GO:0017124 | SH3 domain binding(GO:0017124) |
1.5 | 4.6 | GO:0031731 | CCR6 chemokine receptor binding(GO:0031731) |
0.3 | 4.6 | GO:0003688 | DNA replication origin binding(GO:0003688) |
0.0 | 4.6 | GO:0003823 | antigen binding(GO:0003823) |
0.1 | 4.3 | GO:0004623 | phospholipase A2 activity(GO:0004623) |
0.1 | 4.2 | GO:0008327 | methyl-CpG binding(GO:0008327) |
0.1 | 4.1 | GO:0005164 | tumor necrosis factor receptor binding(GO:0005164) |
0.2 | 3.9 | GO:0016918 | retinal binding(GO:0016918) |
0.1 | 3.9 | GO:0043027 | cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) |
0.1 | 3.6 | GO:0070412 | R-SMAD binding(GO:0070412) |
1.1 | 3.4 | GO:0061505 | DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505) |
0.1 | 3.3 | GO:0005159 | insulin-like growth factor receptor binding(GO:0005159) |
1.0 | 3.0 | GO:0070699 | type II activin receptor binding(GO:0070699) |
Gene overrepresentation in C2:CP category:
Showing 1 to 20 of 41 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 17.0 | NABA_ECM_REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
0.1 | 5.7 | PID_AURORA_A_PATHWAY | Aurora A signaling |
0.1 | 5.3 | PID_FRA_PATHWAY | Validated transcriptional targets of AP1 family members Fra1 and Fra2 |
0.1 | 5.1 | PID_TOLL_ENDOGENOUS_PATHWAY | Endogenous TLR signaling |
0.1 | 5.1 | PID_NFAT_TFPATHWAY | Calcineurin-regulated NFAT-dependent transcription in lymphocytes |
0.1 | 4.7 | PID_AMB2_NEUTROPHILS_PATHWAY | amb2 Integrin signaling |
0.1 | 4.6 | PID_WNT_SIGNALING_PATHWAY | Wnt signaling network |
0.1 | 4.6 | PID_IL2_STAT5_PATHWAY | IL2 signaling events mediated by STAT5 |
0.1 | 4.3 | PID_SYNDECAN_1_PATHWAY | Syndecan-1-mediated signaling events |
0.1 | 4.0 | PID_DELTA_NP63_PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
0.1 | 3.9 | PID_SYNDECAN_3_PATHWAY | Syndecan-3-mediated signaling events |
0.1 | 3.7 | PID_ALK1_PATHWAY | ALK1 signaling events |
0.2 | 3.6 | PID_TCR_RAS_PATHWAY | Ras signaling in the CD4+ TCR pathway |
0.1 | 3.3 | PID_AJDISS_2PATHWAY | Posttranslational regulation of adherens junction stability and dissassembly |
0.1 | 2.8 | PID_TRAIL_PATHWAY | TRAIL signaling pathway |
0.0 | 2.8 | PID_AURORA_B_PATHWAY | Aurora B signaling |
0.1 | 2.6 | PID_UPA_UPAR_PATHWAY | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling |
0.1 | 2.5 | PID_PRL_SIGNALING_EVENTS_PATHWAY | Signaling events mediated by PRL |
0.0 | 2.2 | PID_RAS_PATHWAY | Regulation of Ras family activation |
0.1 | 2.1 | PID_NETRIN_PATHWAY | Netrin-mediated signaling events |
Gene overrepresentation in C2:CP:REACTOME category:
Showing 1 to 20 of 66 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 12.4 | REACTOME_PACKAGING_OF_TELOMERE_ENDS | Genes involved in Packaging Of Telomere Ends |
0.2 | 9.2 | REACTOME_BASIGIN_INTERACTIONS | Genes involved in Basigin interactions |
0.1 | 5.6 | REACTOME_AMYLOIDS | Genes involved in Amyloids |
0.3 | 5.5 | REACTOME_PEPTIDE_HORMONE_BIOSYNTHESIS | Genes involved in Peptide hormone biosynthesis |
0.3 | 5.2 | REACTOME_REVERSIBLE_HYDRATION_OF_CARBON_DIOXIDE | Genes involved in Reversible Hydration of Carbon Dioxide |
0.1 | 5.2 | REACTOME_INTERFERON_GAMMA_SIGNALING | Genes involved in Interferon gamma signaling |
0.3 | 4.6 | REACTOME_UNWINDING_OF_DNA | Genes involved in Unwinding of DNA |
0.1 | 4.6 | REACTOME_BETA_DEFENSINS | Genes involved in Beta defensins |
0.1 | 4.4 | REACTOME_G1_PHASE | Genes involved in G1 Phase |
0.2 | 4.0 | REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS | Genes involved in Homologous recombination repair of replication-independent double-strand breaks |
0.0 | 3.9 | REACTOME_MUSCLE_CONTRACTION | Genes involved in Muscle contraction |
0.1 | 3.8 | REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX | Genes involved in Degradation of the extracellular matrix |
0.2 | 3.6 | REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS | Genes involved in Activation of the AP-1 family of transcription factors |
0.1 | 3.0 | REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
0.1 | 3.0 | REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE | Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere |
0.0 | 2.7 | REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX | Genes involved in Formation of the ternary complex, and subsequently, the 43S complex |
0.0 | 2.6 | REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS | Genes involved in Class B/2 (Secretin family receptors) |
0.0 | 2.6 | REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE | Genes involved in SRP-dependent cotranslational protein targeting to membrane |
0.1 | 2.5 | REACTOME_PYRIMIDINE_METABOLISM | Genes involved in Pyrimidine metabolism |
0.0 | 2.2 | REACTOME_NCAM1_INTERACTIONS | Genes involved in NCAM1 interactions |