Motif ID: TBX19

Z-value: 0.454


Transcription factors associated with TBX19:

Gene SymbolEntrez IDGene Name
TBX19 ENSG00000143178.8 TBX19

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
TBX19hg19_v2_chr1_+_168250194_1682502780.135.4e-01Click!


Activity profile for motif TBX19.

activity profile for motif TBX19


Sorted Z-values histogram for motif TBX19

Sorted Z-values for motif TBX19



Network of associatons between targets according to the STRING database.



First level regulatory network of TBX19

PNG image of the network

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Top targets:


Showing 1 to 20 of 194 entries
PromoterScoreRefseqGene SymbolGene Name
chr20_-_7921090 2.092 ENST00000378789.3
 HAO1
hydroxyacid oxidase (glycolate oxidase) 1
chr7_+_154720173 0.911 ENST00000397551.2
 PAXIP1-AS2
PAXIP1 antisense RNA 2
chr19_+_58514229 0.825 ENST00000546949.1
ENST00000553254.1
ENST00000547364.1
 CTD-2368P22.1


HCG1811579; Uncharacterized protein


chr3_+_94657086 0.696 ENST00000463200.1
 LINC00879
long intergenic non-protein coding RNA 879
chr3_+_98482175 0.692 ENST00000485391.1
ENST00000492254.1
 ST3GAL6

ST3 beta-galactoside alpha-2,3-sialyltransferase 6

chr2_+_143886877 0.529 ENST00000295095.6
 ARHGAP15
Rho GTPase activating protein 15
chr17_-_39203519 0.524 ENST00000542137.1
ENST00000391419.3
 KRTAP2-1

keratin associated protein 2-1

chr1_+_172389821 0.366 ENST00000367727.4
 C1orf105
chromosome 1 open reading frame 105
chr6_-_27880174 0.344 ENST00000303324.2
 OR2B2
olfactory receptor, family 2, subfamily B, member 2
chr2_-_113594279 0.340 ENST00000416750.1
ENST00000418817.1
ENST00000263341.2
 IL1B


interleukin 1, beta


chr12_-_9360966 0.337 ENST00000261336.2
 PZP
pregnancy-zone protein
chr7_-_148580563 0.331 ENST00000476773.1
 EZH2
enhancer of zeste homolog 2 (Drosophila)
chr14_+_23727694 0.324 ENST00000399905.1
ENST00000470456.1
 C14orf164

chromosome 14 open reading frame 164

chr1_-_63988846 0.321 ENST00000283568.8
ENST00000371092.3
ENST00000271002.10
 ITGB3BP


integrin beta 3 binding protein (beta3-endonexin)


chr6_+_147091575 0.285 ENST00000326916.8
ENST00000470716.2
ENST00000367488.1
 ADGB


androglobin


chr17_+_3118915 0.273 ENST00000304094.1
 OR1A1
olfactory receptor, family 1, subfamily A, member 1
chr11_+_5474638 0.267 ENST00000341449.2
 OR51I2
olfactory receptor, family 51, subfamily I, member 2
chr8_+_94767072 0.266 ENST00000452276.1
ENST00000453321.3
ENST00000498673.1
ENST00000518319.1
 TMEM67



transmembrane protein 67



chr19_-_58514129 0.265 ENST00000552184.1
ENST00000546715.1
ENST00000536132.1
ENST00000547828.1
ENST00000547121.1
ENST00000551380.1
 ZNF606





zinc finger protein 606





chr11_-_84028180 0.257 ENST00000280241.8
 DLG2
discs, large homolog 2 (Drosophila)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 35 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 2.1 GO:0009441 glycolate metabolic process(GO:0009441)
0.0 0.7 GO:0097503 sialylation(GO:0097503)
0.1 0.4 GO:0032455 nerve growth factor processing(GO:0032455)
0.0 0.4 GO:0014827 intestine smooth muscle contraction(GO:0014827)
0.0 0.4 GO:0010826 negative regulation of centrosome duplication(GO:0010826)
0.0 0.4 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.1 0.3 GO:0060557 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.1 0.3 GO:0036333 hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
0.1 0.3 GO:0090202 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.1 0.3 GO:0070945 neutrophil mediated killing of gram-negative bacterium(GO:0070945)
0.1 0.3 GO:0021633 optic nerve structural organization(GO:0021633)
0.0 0.2 GO:0061009 common bile duct development(GO:0061009)
0.0 0.2 GO:1900005 positive regulation of serine-type endopeptidase activity(GO:1900005) positive regulation of serine-type peptidase activity(GO:1902573)
0.0 0.2 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.2 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.1 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
0.0 0.1 GO:0045014 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.0 0.1 GO:0015772 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.0 0.1 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.0 0.1 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)

Gene overrepresentation in cellular_component category:

Showing 1 to 13 of 13 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.1 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.7 GO:0036038 MKS complex(GO:0036038)
0.0 0.3 GO:0097255 R2TP complex(GO:0097255)
0.0 0.3 GO:0045120 pronucleus(GO:0045120)
0.0 0.3 GO:0033010 paranodal junction(GO:0033010)
0.0 0.2 GO:0060091 kinocilium(GO:0060091)
0.0 0.2 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.1 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.1 GO:0098536 deuterosome(GO:0098536)
0.0 0.1 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.1 GO:0030936 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.0 0.0 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.0 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 21 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.7 2.1 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.2 0.7 GO:0052798 beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798)
0.0 0.4 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.4 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.4 GO:0031005 filamin binding(GO:0031005)
0.0 0.3 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0 0.3 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.0 0.3 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.3 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.2 GO:0030197 extracellular matrix constituent, lubricant activity(GO:0030197)
0.0 0.1 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.0 0.1 GO:0008515 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.0 0.1 GO:0003896 DNA primase activity(GO:0003896)
0.0 0.1 GO:1990259 protein-glutamine N-methyltransferase activity(GO:0036009) histone-glutamine methyltransferase activity(GO:1990259)
0.0 0.1 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.0 0.1 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.1 GO:0008453 alanine-glyoxylate transaminase activity(GO:0008453)
0.0 0.1 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.1 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.0 0.0 GO:0000384 first spliceosomal transesterification activity(GO:0000384)

Gene overrepresentation in C2:CP category:

Showing 1 to 1 of 1 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.3 PID_ANTHRAX_PATHWAY Cellular roles of Anthrax toxin

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 4 of 4 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.7 REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.4 REACTOME_SEROTONIN_RECEPTORS Genes involved in Serotonin receptors
0.0 0.3 REACTOME_NRIF_SIGNALS_CELL_DEATH_FROM_THE_NUCLEUS Genes involved in NRIF signals cell death from the nucleus
0.0 0.1 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK