Motif ID: TBX2
Z-value: 0.677

Transcription factors associated with TBX2:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
TBX2 | ENSG00000121068.9 | TBX2 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
TBX2 | hg19_v2_chr17_+_59477233_59477263 | 0.06 | 7.6e-01 | Click! |
Top targets:
Showing 1 to 20 of 200 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 161 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.4 | 2.2 | GO:0035803 | egg coat formation(GO:0035803) |
0.1 | 2.0 | GO:0009235 | cobalamin metabolic process(GO:0009235) |
0.3 | 1.7 | GO:0007079 | mitotic chromosome movement towards spindle pole(GO:0007079) |
0.5 | 1.5 | GO:0019858 | cytosine metabolic process(GO:0019858) |
0.0 | 1.4 | GO:0050911 | detection of chemical stimulus involved in sensory perception of smell(GO:0050911) |
0.4 | 1.1 | GO:1904956 | regulation of midbrain dopaminergic neuron differentiation(GO:1904956) |
0.3 | 1.0 | GO:0046110 | xanthine metabolic process(GO:0046110) |
0.2 | 1.0 | GO:0038195 | urokinase plasminogen activator signaling pathway(GO:0038195) |
0.1 | 1.0 | GO:0021603 | cranial nerve formation(GO:0021603) |
0.1 | 1.0 | GO:0072520 | seminiferous tubule development(GO:0072520) |
0.1 | 0.9 | GO:0001833 | inner cell mass cell proliferation(GO:0001833) |
0.0 | 0.9 | GO:0000920 | cell separation after cytokinesis(GO:0000920) |
0.2 | 0.8 | GO:0035627 | ceramide transport(GO:0035627) |
0.2 | 0.8 | GO:0032487 | regulation of Rap protein signal transduction(GO:0032487) |
0.2 | 0.7 | GO:0016103 | diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653) |
0.1 | 0.7 | GO:0006436 | tryptophanyl-tRNA aminoacylation(GO:0006436) |
0.1 | 0.7 | GO:0006689 | ganglioside catabolic process(GO:0006689) |
0.2 | 0.6 | GO:0048627 | myoblast development(GO:0048627) |
0.1 | 0.6 | GO:0086053 | AV node cell to bundle of His cell communication by electrical coupling(GO:0086053) |
0.1 | 0.6 | GO:0010760 | negative regulation of macrophage chemotaxis(GO:0010760) |
Gene overrepresentation in cellular_component category:
Showing 1 to 20 of 59 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 4.8 | GO:1904724 | tertiary granule lumen(GO:1904724) |
0.1 | 1.7 | GO:0031616 | spindle pole centrosome(GO:0031616) |
0.1 | 1.0 | GO:0071438 | invadopodium membrane(GO:0071438) |
0.1 | 1.0 | GO:1990023 | mitotic spindle midzone(GO:1990023) |
0.0 | 1.0 | GO:0002102 | podosome(GO:0002102) |
0.1 | 0.9 | GO:0090543 | Flemming body(GO:0090543) |
0.1 | 0.8 | GO:0097209 | epidermal lamellar body(GO:0097209) |
0.0 | 0.8 | GO:0051233 | spindle midzone(GO:0051233) |
0.2 | 0.7 | GO:0005889 | hydrogen:potassium-exchanging ATPase complex(GO:0005889) |
0.1 | 0.7 | GO:0031262 | Ndc80 complex(GO:0031262) |
0.0 | 0.7 | GO:0005922 | connexon complex(GO:0005922) |
0.2 | 0.6 | GO:0000811 | GINS complex(GO:0000811) |
0.1 | 0.6 | GO:0036021 | endolysosome lumen(GO:0036021) |
0.1 | 0.6 | GO:0000796 | condensin complex(GO:0000796) |
0.0 | 0.6 | GO:0097546 | ciliary base(GO:0097546) |
0.2 | 0.5 | GO:0032133 | chromosome passenger complex(GO:0032133) |
0.0 | 0.5 | GO:0042382 | paraspeckles(GO:0042382) |
0.0 | 0.5 | GO:0000347 | THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445) |
0.0 | 0.5 | GO:1990316 | ATG1/ULK1 kinase complex(GO:1990316) |
0.0 | 0.5 | GO:0008385 | IkappaB kinase complex(GO:0008385) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 105 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 3.2 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
0.2 | 2.4 | GO:0032190 | acrosin binding(GO:0032190) |
0.0 | 1.8 | GO:0008574 | ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) |
0.2 | 1.3 | GO:0004126 | cytidine deaminase activity(GO:0004126) |
0.1 | 1.1 | GO:0039706 | co-receptor binding(GO:0039706) |
0.3 | 1.0 | GO:0030377 | urokinase plasminogen activator receptor activity(GO:0030377) |
0.1 | 1.0 | GO:0043546 | molybdopterin cofactor binding(GO:0043546) |
0.0 | 0.9 | GO:0004984 | olfactory receptor activity(GO:0004984) |
0.2 | 0.8 | GO:0034040 | lipid-transporting ATPase activity(GO:0034040) |
0.0 | 0.8 | GO:0035615 | clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748) |
0.1 | 0.7 | GO:0008401 | retinoic acid 4-hydroxylase activity(GO:0008401) |
0.1 | 0.7 | GO:0004830 | tryptophan-tRNA ligase activity(GO:0004830) |
0.1 | 0.7 | GO:0004563 | beta-N-acetylhexosaminidase activity(GO:0004563) |
0.0 | 0.7 | GO:0005164 | tumor necrosis factor receptor binding(GO:0005164) |
0.1 | 0.6 | GO:0086077 | gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling(GO:0086077) |
0.0 | 0.6 | GO:0043138 | 3'-5' DNA helicase activity(GO:0043138) |
0.0 | 0.6 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
0.0 | 0.6 | GO:0043394 | proteoglycan binding(GO:0043394) |
0.2 | 0.5 | GO:0003839 | gamma-glutamylcyclotransferase activity(GO:0003839) |
0.1 | 0.5 | GO:0033743 | peptide-methionine (R)-S-oxide reductase activity(GO:0033743) |
Gene overrepresentation in C2:CP category:
Showing 1 to 20 of 20 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 5.0 | NABA_ECM_REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
0.0 | 1.7 | PID_AURORA_A_PATHWAY | Aurora A signaling |
0.0 | 1.2 | PID_ARF6_DOWNSTREAM_PATHWAY | Arf6 downstream pathway |
0.0 | 1.1 | PID_CIRCADIAN_PATHWAY | Circadian rhythm pathway |
0.0 | 1.1 | PID_WNT_SIGNALING_PATHWAY | Wnt signaling network |
0.1 | 0.6 | ST_PAC1_RECEPTOR_PATHWAY | PAC1 Receptor Pathway |
0.0 | 0.6 | ST_STAT3_PATHWAY | STAT3 Pathway |
0.0 | 0.6 | PID_IL23_PATHWAY | IL23-mediated signaling events |
0.0 | 0.6 | PID_RXR_VDR_PATHWAY | RXR and RAR heterodimerization with other nuclear receptor |
0.0 | 0.6 | PID_AURORA_B_PATHWAY | Aurora B signaling |
0.0 | 0.6 | SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES | Genes related to regulation of the actin cytoskeleton |
0.0 | 0.6 | NABA_PROTEOGLYCANS | Genes encoding proteoglycans |
0.0 | 0.6 | PID_TCR_PATHWAY | TCR signaling in naïve CD4+ T cells |
0.0 | 0.5 | SA_G1_AND_S_PHASES | Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition. |
0.0 | 0.5 | PID_NFKAPPAB_CANONICAL_PATHWAY | Canonical NF-kappaB pathway |
0.0 | 0.4 | PID_S1P_S1P1_PATHWAY | S1P1 pathway |
0.0 | 0.4 | PID_NECTIN_PATHWAY | Nectin adhesion pathway |
0.0 | 0.3 | SA_FAS_SIGNALING | The TNF-type receptor Fas induces apoptosis on ligand binding. |
0.0 | 0.3 | PID_TCR_JNK_PATHWAY | JNK signaling in the CD4+ TCR pathway |
0.0 | 0.3 | ST_T_CELL_SIGNAL_TRANSDUCTION | T Cell Signal Transduction |
Gene overrepresentation in C2:CP:REACTOME category:
Showing 1 to 20 of 30 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 1.5 | REACTOME_MITOTIC_PROMETAPHASE | Genes involved in Mitotic Prometaphase |
0.0 | 1.4 | REACTOME_OLFACTORY_SIGNALING_PATHWAY | Genes involved in Olfactory Signaling Pathway |
0.0 | 1.3 | REACTOME_PYRIMIDINE_METABOLISM | Genes involved in Pyrimidine metabolism |
0.1 | 1.0 | REACTOME_PURINE_CATABOLISM | Genes involved in Purine catabolism |
0.0 | 1.0 | REACTOME_KINESINS | Genes involved in Kinesins |
0.0 | 0.9 | REACTOME_GLUCURONIDATION | Genes involved in Glucuronidation |
0.0 | 0.9 | REACTOME_SIGNAL_REGULATORY_PROTEIN_SIRP_FAMILY_INTERACTIONS | Genes involved in Signal regulatory protein (SIRP) family interactions |
0.0 | 0.9 | REACTOME_GROWTH_HORMONE_RECEPTOR_SIGNALING | Genes involved in Growth hormone receptor signaling |
0.0 | 0.8 | REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS | Genes involved in ABCA transporters in lipid homeostasis |
0.0 | 0.8 | REACTOME_POST_TRANSLATIONAL_MODIFICATION_SYNTHESIS_OF_GPI_ANCHORED_PROTEINS | Genes involved in Post-translational modification: synthesis of GPI-anchored proteins |
0.0 | 0.7 | REACTOME_A_TETRASACCHARIDE_LINKER_SEQUENCE_IS_REQUIRED_FOR_GAG_SYNTHESIS | Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis |
0.0 | 0.7 | REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE | Genes involved in Cytochrome P450 - arranged by substrate type |
0.0 | 0.7 | REACTOME_GLYCOSPHINGOLIPID_METABOLISM | Genes involved in Glycosphingolipid metabolism |
0.0 | 0.6 | REACTOME_UNWINDING_OF_DNA | Genes involved in Unwinding of DNA |
0.0 | 0.6 | REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS | Genes involved in Termination of O-glycan biosynthesis |
0.0 | 0.5 | REACTOME_RETROGRADE_NEUROTROPHIN_SIGNALLING | Genes involved in Retrograde neurotrophin signalling |
0.0 | 0.5 | REACTOME_NUCLEOTIDE_LIKE_PURINERGIC_RECEPTORS | Genes involved in Nucleotide-like (purinergic) receptors |
0.0 | 0.5 | REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION | Genes involved in Cytosolic tRNA aminoacylation |
0.0 | 0.4 | REACTOME_POL_SWITCHING | Genes involved in Polymerase switching |
0.0 | 0.4 | REACTOME_COMMON_PATHWAY | Genes involved in Common Pathway |