Motif ID: TFDP1

Z-value: 0.904


Transcription factors associated with TFDP1:

Gene SymbolEntrez IDGene Name
TFDP1 ENSG00000198176.8 TFDP1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
TFDP1hg19_v2_chr13_+_114238997_1142390770.734.8e-05Click!


Activity profile for motif TFDP1.

activity profile for motif TFDP1


Sorted Z-values histogram for motif TFDP1

Sorted Z-values for motif TFDP1



Network of associatons between targets according to the STRING database.



First level regulatory network of TFDP1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_+_20403997 1.333 ENST00000535432.1
 E2F3
E2F transcription factor 3
chr4_-_83351005 1.314 ENST00000295470.5
 HNRNPDL
heterogeneous nuclear ribonucleoprotein D-like
chr2_+_174219548 1.267 ENST00000347703.3
ENST00000392567.2
ENST00000306721.3
ENST00000410101.3
ENST00000410019.3
 CDCA7




cell division cycle associated 7




chr1_+_212208919 1.261 ENST00000366991.4
ENST00000542077.1
 DTL

denticleless E3 ubiquitin protein ligase homolog (Drosophila)

chr17_+_30814707 1.191 ENST00000584792.1
 CDK5R1
cyclin-dependent kinase 5, regulatory subunit 1 (p35)
chr16_+_46723552 1.173 ENST00000219097.2
ENST00000568364.2
 ORC6

origin recognition complex, subunit 6

chr11_-_64851496 1.148 ENST00000404147.3
ENST00000275517.3
 CDCA5

cell division cycle associated 5

chr10_+_105127704 1.009 ENST00000369839.3
ENST00000351396.4
 TAF5

TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa

chr9_+_36572851 0.995 ENST00000298048.2
ENST00000538311.1
ENST00000536987.1
ENST00000545008.1
ENST00000536860.1
ENST00000536329.1
ENST00000541717.1
ENST00000543751.1
 MELK







maternal embryonic leucine zipper kinase







chr6_-_86352982 0.980 ENST00000369622.3
 SYNCRIP
synaptotagmin binding, cytoplasmic RNA interacting protein
chr16_-_87903079 0.942 ENST00000261622.4
 SLC7A5
solute carrier family 7 (amino acid transporter light chain, L system), member 5
chr11_-_118966167 0.932 ENST00000530167.1
 H2AFX
H2A histone family, member X
chr19_+_34287174 0.922 ENST00000587559.1
ENST00000588637.1
 KCTD15

potassium channel tetramerization domain containing 15

chrX_+_64887512 0.895 ENST00000360270.5
 MSN
moesin
chr8_-_95908902 0.894 ENST00000520509.1
 CCNE2
cyclin E2
chr6_-_153304697 0.890 ENST00000367241.3
 FBXO5
F-box protein 5
chr19_-_48673580 0.884 ENST00000427526.2
 LIG1
ligase I, DNA, ATP-dependent
chr19_-_48673552 0.867 ENST00000536218.1
ENST00000596549.1
 LIG1

ligase I, DNA, ATP-dependent

chr15_+_69706585 0.852 ENST00000559279.1
ENST00000395392.2
 KIF23

kinesin family member 23

chr1_-_6321035 0.850 ENST00000377893.2
 GPR153
G protein-coupled receptor 153

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 448 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 5.8 GO:0006270 DNA replication initiation(GO:0006270)
0.0 2.4 GO:0071349 interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349)
0.0 2.2 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.0 2.2 GO:0043486 histone exchange(GO:0043486)
0.0 2.2 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079)
0.4 2.0 GO:0033567 DNA replication, Okazaki fragment processing(GO:0033567)
0.2 1.7 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.1 1.7 GO:0051639 actin filament network formation(GO:0051639)
0.5 1.6 GO:0071790 spindle pole body duplication(GO:0030474) spindle pole body organization(GO:0051300) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790)
0.2 1.6 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.1 1.6 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
0.2 1.5 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.1 1.5 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.2 1.4 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.2 1.4 GO:0038026 reelin-mediated signaling pathway(GO:0038026)
0.1 1.4 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 1.4 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 1.4 GO:1902808 positive regulation of cell cycle G1/S phase transition(GO:1902808)
0.1 1.3 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.0 1.3 GO:0050690 regulation of defense response to virus by virus(GO:0050690)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 176 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 4.3 GO:0000922 spindle pole(GO:0000922)
0.1 2.3 GO:0001741 XY body(GO:0001741)
0.0 2.2 GO:0072686 mitotic spindle(GO:0072686)
0.1 2.0 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.2 1.7 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.1 1.7 GO:0000812 Swr1 complex(GO:0000812)
0.1 1.7 GO:0031143 pseudopodium(GO:0031143)
0.0 1.7 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.5 1.6 GO:0070762 nuclear pore transmembrane ring(GO:0070762)
0.4 1.6 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
0.1 1.6 GO:0042555 MCM complex(GO:0042555)
0.1 1.5 GO:0005642 annulate lamellae(GO:0005642)
0.2 1.4 GO:0097452 GAIT complex(GO:0097452)
0.0 1.4 GO:0043596 nuclear replication fork(GO:0043596)
0.2 1.3 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.2 1.3 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.2 1.3 GO:0031415 NatA complex(GO:0031415)
0.3 1.2 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.2 1.1 GO:0097149 centralspindlin complex(GO:0097149)
0.1 1.1 GO:0005641 nuclear envelope lumen(GO:0005641)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 255 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 3.1 GO:0031490 chromatin DNA binding(GO:0031490)
0.1 2.1 GO:0003688 DNA replication origin binding(GO:0003688)
0.2 1.9 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.0 1.9 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 1.8 GO:0019212 phosphatase inhibitor activity(GO:0019212)
0.2 1.7 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1 1.7 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.1 1.7 GO:0005521 lamin binding(GO:0005521)
0.1 1.6 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 1.6 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 1.6 GO:0019003 GDP binding(GO:0019003)
0.1 1.5 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.1 1.5 GO:0032794 GTPase activating protein binding(GO:0032794)
0.1 1.4 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.3 1.3 GO:0038025 reelin receptor activity(GO:0038025)
0.0 1.3 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 1.3 GO:0008143 poly(A) binding(GO:0008143)
0.0 1.3 GO:0019894 kinesin binding(GO:0019894)
0.4 1.2 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.1 1.2 GO:0005049 nuclear export signal receptor activity(GO:0005049)

Gene overrepresentation in C2:CP category:

Showing 1 to 20 of 47 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 5.3 PID_E2F_PATHWAY E2F transcription factor network
0.1 4.1 PID_REELIN_PATHWAY Reelin signaling pathway
0.1 3.8 PID_AURORA_B_PATHWAY Aurora B signaling
0.1 3.2 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 2.6 PID_ILK_PATHWAY Integrin-linked kinase signaling
0.0 2.4 PID_FANCONI_PATHWAY Fanconi anemia pathway
0.0 1.7 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.1 1.6 SA_G2_AND_M_PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 1.3 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 1.2 PID_FRA_PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 1.2 PID_CXCR4_PATHWAY CXCR4-mediated signaling events
0.0 1.1 PID_ER_NONGENOMIC_PATHWAY Plasma membrane estrogen receptor signaling
0.0 1.0 PID_INTEGRIN4_PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 1.0 PID_RAS_PATHWAY Regulation of Ras family activation
0.0 1.0 ST_INTEGRIN_SIGNALING_PATHWAY Integrin Signaling Pathway
0.0 0.9 PID_BARD1_PATHWAY BARD1 signaling events
0.0 0.9 ST_PHOSPHOINOSITIDE_3_KINASE_PATHWAY PI3K Pathway
0.0 0.9 PID_LKB1_PATHWAY LKB1 signaling events
0.0 0.9 PID_CDC42_PATHWAY CDC42 signaling events
0.0 0.9 PID_CD8_TCR_PATHWAY TCR signaling in naïve CD8+ T cells

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 81 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 4.2 REACTOME_ACTIVATION_OF_THE_PRE_REPLICATIVE_COMPLEX Genes involved in Activation of the pre-replicative complex
0.2 4.2 REACTOME_LAGGING_STRAND_SYNTHESIS Genes involved in Lagging Strand Synthesis
0.3 3.7 REACTOME_CDC6_ASSOCIATION_WITH_THE_ORC_ORIGIN_COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.1 2.9 REACTOME_CRMPS_IN_SEMA3A_SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 2.6 REACTOME_G0_AND_EARLY_G1 Genes involved in G0 and Early G1
0.0 2.2 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 2.0 REACTOME_KINESINS Genes involved in Kinesins
0.0 2.0 REACTOME_MRNA_SPLICING_MINOR_PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.1 1.9 REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 1.9 REACTOME_G1_PHASE Genes involved in G1 Phase
0.0 1.7 REACTOME_RECYCLING_PATHWAY_OF_L1 Genes involved in Recycling pathway of L1
0.1 1.6 REACTOME_PLATELET_SENSITIZATION_BY_LDL Genes involved in Platelet sensitization by LDL
0.0 1.5 REACTOME_PTM_GAMMA_CARBOXYLATION_HYPUSINE_FORMATION_AND_ARYLSULFATASE_ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 1.4 REACTOME_BASIGIN_INTERACTIONS Genes involved in Basigin interactions
0.0 1.3 REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.1 1.2 REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 1.1 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 1.1 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 1.1 REACTOME_RNA_POL_II_TRANSCRIPTION_PRE_INITIATION_AND_PROMOTER_OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 1.1 REACTOME_DESTABILIZATION_OF_MRNA_BY_AUF1_HNRNP_D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)