Motif ID: UAUUGCU

Z-value: 0.595


Mature miRNA associated with seed UAUUGCU:

NamemiRBase Accession
hsa-miR-137 MIMAT0000429



Activity profile for motif UAUUGCU.

activity profile for motif UAUUGCU


Sorted Z-values histogram for motif UAUUGCU

Sorted Z-values for motif UAUUGCU



Network of associatons between targets according to the STRING database.



First level regulatory network of UAUUGCU

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_+_106685079 1.312 ENST00000265717.4
PRKAR2B
protein kinase, cAMP-dependent, regulatory, type II, beta
chr20_+_37434329 1.167 ENST00000299824.1
ENST00000373331.2
PPP1R16B

protein phosphatase 1, regulatory subunit 16B

chr6_-_90121938 1.124 ENST00000369415.4
RRAGD
Ras-related GTP binding D
chr4_-_23891693 1.109 ENST00000264867.2
PPARGC1A
peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
chr1_-_46598284 1.084 ENST00000423209.1
ENST00000262741.5
PIK3R3

phosphoinositide-3-kinase, regulatory subunit 3 (gamma)

chr13_-_29292956 1.083 ENST00000266943.6
SLC46A3
solute carrier family 46, member 3
chr7_-_117513540 1.030 ENST00000160373.3
CTTNBP2
cortactin binding protein 2
chr4_+_55524085 0.870 ENST00000412167.2
ENST00000288135.5
KIT

v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog

chr7_-_122526799 0.852 ENST00000334010.7
ENST00000313070.7
CADPS2

Ca++-dependent secretion activator 2

chr17_-_1532106 0.827 ENST00000301335.5
ENST00000382147.4
SLC43A2

solute carrier family 43 (amino acid system L transporter), member 2

chr2_-_73460334 0.747 ENST00000258083.2
PRADC1
protease-associated domain containing 1
chr2_+_85981008 0.665 ENST00000306279.3
ATOH8
atonal homolog 8 (Drosophila)
chr11_-_61348576 0.647 ENST00000263846.4
SYT7
synaptotagmin VII
chr16_+_28303804 0.613 ENST00000341901.4
SBK1
SH3 domain binding kinase 1
chr14_+_79745746 0.607 ENST00000281127.7
NRXN3
neurexin 3
chr5_-_83680603 0.606 ENST00000296591.5
EDIL3
EGF-like repeats and discoidin I-like domains 3
chr8_-_40755333 0.582 ENST00000297737.6
ENST00000315769.7
ZMAT4

zinc finger, matrin-type 4

chr9_+_136325089 0.568 ENST00000291722.7
ENST00000316948.4
ENST00000540581.1
CACFD1


calcium channel flower domain containing 1


chr1_-_89591749 0.554 ENST00000370466.3
GBP2
guanylate binding protein 2, interferon-inducible
chr1_+_95582881 0.523 ENST00000370203.4
ENST00000456991.1
TMEM56

transmembrane protein 56


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 116 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 1.3 GO:0097338 response to clozapine(GO:0097338)
0.4 1.2 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.4 1.1 GO:1901860 positive regulation of mitochondrial DNA metabolic process(GO:1901860)
0.1 1.1 GO:0071233 cellular response to leucine(GO:0071233)
0.3 0.9 GO:0038109 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109) erythropoietin-mediated signaling pathway(GO:0038162)
0.1 0.9 GO:1990504 dense core granule exocytosis(GO:1990504)
0.0 0.8 GO:2001275 positive regulation of glucose import in response to insulin stimulus(GO:2001275)
0.0 0.8 GO:0051450 myoblast proliferation(GO:0051450)
0.0 0.7 GO:1902475 L-alpha-amino acid transmembrane transport(GO:1902475)
0.2 0.6 GO:1990927 short-term synaptic potentiation(GO:1990926) calcium ion regulated lysosome exocytosis(GO:1990927)
0.1 0.6 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.1 0.5 GO:0098886 modification of dendritic spine(GO:0098886)
0.1 0.5 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.5 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.5 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.1 0.4 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.1 0.4 GO:0010748 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
0.1 0.4 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.4 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.0 0.4 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 47 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.3 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.2 1.1 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 1.1 GO:0097440 apical dendrite(GO:0097440)
0.0 0.8 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.1 0.6 GO:0032009 early phagosome(GO:0032009)
0.0 0.5 GO:0042629 mast cell granule(GO:0042629)
0.0 0.4 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.4 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.4 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.3 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.3 GO:0042382 paraspeckles(GO:0042382)
0.0 0.3 GO:0097546 ciliary base(GO:0097546)
0.1 0.2 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.1 0.2 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.1 0.2 GO:0043291 RAVE complex(GO:0043291)
0.0 0.2 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.0 0.2 GO:0044308 axonal spine(GO:0044308)
0.0 0.2 GO:0036398 TCR signalosome(GO:0036398)
0.0 0.2 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.0 0.2 GO:1990635 proximal dendrite(GO:1990635)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 84 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.3 GO:0035014 phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.1 1.3 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 1.2 GO:0019003 GDP binding(GO:0019003)
0.1 1.1 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.7 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0 0.6 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.6 GO:0070888 E-box binding(GO:0070888)
0.0 0.6 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.1 0.5 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.5 GO:0008266 poly(U) RNA binding(GO:0008266)
0.1 0.4 GO:0001727 lipid kinase activity(GO:0001727)
0.1 0.4 GO:0004340 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.4 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.0 0.4 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.4 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.4 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.1 0.3 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.1 0.3 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 0.3 GO:0052832 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.0 0.3 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)

Gene overrepresentation in C2:CP category:

Showing 1 to 7 of 7 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.1 PID_TRAIL_PATHWAY TRAIL signaling pathway
0.0 0.8 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.0 0.6 PID_INTEGRIN5_PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.4 PID_EPO_PATHWAY EPO signaling pathway
0.0 0.3 PID_ALK2_PATHWAY ALK2 signaling events
0.0 0.2 PID_RANBP2_PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.0 PID_VEGFR1_PATHWAY VEGFR1 specific signals

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 13 of 13 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.2 REACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_CREB Genes involved in PKA-mediated phosphorylation of CREB
0.1 1.1 REACTOME_IL_7_SIGNALING Genes involved in Interleukin-7 signaling
0.0 1.1 REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.9 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.8 REACTOME_REGULATION_OF_KIT_SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.6 REACTOME_GLUCOSE_TRANSPORT Genes involved in Glucose transport
0.0 0.4 REACTOME_SOS_MEDIATED_SIGNALLING Genes involved in SOS-mediated signalling
0.0 0.4 REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.3 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.3 REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.2 REACTOME_ERKS_ARE_INACTIVATED Genes involved in ERKs are inactivated
0.0 0.2 REACTOME_TRAF3_DEPENDENT_IRF_ACTIVATION_PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.1 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_LATE_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane