Motif ID: UBP1

Z-value: 0.370


Transcription factors associated with UBP1:

Gene SymbolEntrez IDGene Name
UBP1 ENSG00000153560.7 UBP1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
UBP1hg19_v2_chr3_-_33481835_33481905-0.573.7e-03Click!


Activity profile for motif UBP1.

activity profile for motif UBP1


Sorted Z-values histogram for motif UBP1

Sorted Z-values for motif UBP1



Network of associatons between targets according to the STRING database.



First level regulatory network of UBP1

PNG image of the network

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Top targets:


Showing 1 to 20 of 91 entries
PromoterScoreRefseqGene SymbolGene Name
chr22_+_38071615 1.670 ENST00000215909.5
 LGALS1
lectin, galactoside-binding, soluble, 1
chr4_-_57524061 1.110 ENST00000508121.1
 HOPX
HOP homeobox
chr19_-_51538148 1.070 ENST00000319590.4
ENST00000250351.4
 KLK12

kallikrein-related peptidase 12

chr12_-_47473425 0.978 ENST00000550413.1
 AMIGO2
adhesion molecule with Ig-like domain 2
chr19_+_917287 0.924 ENST00000592648.1
ENST00000234371.5
 KISS1R

KISS1 receptor

chr17_+_74381343 0.899 ENST00000392496.3
 SPHK1
sphingosine kinase 1
chr2_+_228678550 0.738 ENST00000409189.3
ENST00000358813.4
 CCL20

chemokine (C-C motif) ligand 20

chr17_-_5138099 0.687 ENST00000571800.1
ENST00000574081.1
ENST00000399600.4
ENST00000574297.1
 SCIMP



SLP adaptor and CSK interacting membrane protein



chr12_-_8815215 0.614 ENST00000544889.1
ENST00000543369.1
 MFAP5

microfibrillar associated protein 5

chr12_-_8815299 0.599 ENST00000535336.1
 MFAP5
microfibrillar associated protein 5
chr9_-_35685452 0.574 ENST00000607559.1
 TPM2
tropomyosin 2 (beta)
chr1_-_150208320 0.525 ENST00000534220.1
 ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr12_+_47473369 0.484 ENST00000546455.1
 PCED1B
PC-esterase domain containing 1B
chr19_+_41257084 0.477 ENST00000601393.1
 SNRPA
small nuclear ribonucleoprotein polypeptide A
chr11_-_102668879 0.470 ENST00000315274.6
 MMP1
matrix metallopeptidase 1 (interstitial collagenase)
chr12_+_100041527 0.426 ENST00000324341.1
 FAM71C
family with sequence similarity 71, member C
chr2_-_89442621 0.399 ENST00000492167.1
 IGKV3-20
immunoglobulin kappa variable 3-20
chr10_-_75676400 0.346 ENST00000412307.2
 C10orf55
chromosome 10 open reading frame 55
chr13_-_23949671 0.342 ENST00000402364.1
 SACS
spastic ataxia of Charlevoix-Saguenay (sacsin)
chr1_-_150208291 0.325 ENST00000533654.1
 ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 26 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 1.7 GO:0002317 plasma cell differentiation(GO:0002317)
0.0 1.5 GO:0043486 histone exchange(GO:0043486)
0.0 1.2 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 1.1 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.0 1.0 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.3 0.9 GO:0046521 sphingoid catabolic process(GO:0046521)
0.2 0.7 GO:0045360 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.0 0.5 GO:1900363 regulation of mRNA polyadenylation(GO:1900363)
0.0 0.5 GO:0032461 positive regulation of protein oligomerization(GO:0032461)
0.1 0.4 GO:0052551 response to defense-related nitric oxide production by other organism involved in symbiotic interaction(GO:0052551) response to defense-related host nitric oxide production(GO:0052565)
0.0 0.4 GO:0003094 glomerular filtration(GO:0003094)
0.1 0.3 GO:0072429 response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.0 0.3 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.0 0.3 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 0.3 GO:0048368 lateral mesoderm development(GO:0048368)
0.0 0.3 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 0.2 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.0 0.2 GO:0001992 regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.0 0.2 GO:0050884 neuromuscular process controlling posture(GO:0050884)
0.0 0.1 GO:0002728 negative regulation of natural killer cell cytokine production(GO:0002728)

Gene overrepresentation in cellular_component category:

Showing 1 to 11 of 11 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.5 GO:0000812 Swr1 complex(GO:0000812)
0.0 1.2 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.1 0.7 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.6 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.5 GO:0005685 U1 snRNP(GO:0005685)
0.1 0.4 GO:0071749 IgA immunoglobulin complex(GO:0071745) IgA immunoglobulin complex, circulating(GO:0071746) monomeric IgA immunoglobulin complex(GO:0071748) polymeric IgA immunoglobulin complex(GO:0071749) secretory IgA immunoglobulin complex(GO:0071751)
0.0 0.4 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 0.3 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.1 0.3 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.0 0.3 GO:0070852 cell body fiber(GO:0070852)
0.0 0.2 GO:0005686 U2 snRNP(GO:0005686)

Gene overrepresentation in molecular_function category:

Showing 1 to 19 of 19 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 1.7 GO:0030395 lactose binding(GO:0030395)
0.0 1.5 GO:0019212 phosphatase inhibitor activity(GO:0019212)
0.0 1.2 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 0.9 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.0 0.9 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.2 0.7 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.1 0.5 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.0 0.4 GO:0004383 guanylate cyclase activity(GO:0004383)
0.1 0.3 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.3 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.3 GO:0070628 proteasome binding(GO:0070628)
0.0 0.3 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.0 0.2 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.2 GO:0030620 U2 snRNA binding(GO:0030620)
0.0 0.2 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.1 GO:0004958 prostaglandin F receptor activity(GO:0004958)
0.0 0.1 GO:0051373 FATZ binding(GO:0051373)
0.0 0.1 GO:0032396 inhibitory MHC class I receptor activity(GO:0032396)
0.0 0.1 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)

Gene overrepresentation in C2:CP category:

Showing 1 to 3 of 3 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.7 PID_RAS_PATHWAY Regulation of Ras family activation
0.0 1.2 PID_NOTCH_PATHWAY Notch signaling pathway
0.0 0.9 PID_S1P_META_PATHWAY Sphingosine 1-phosphate (S1P) pathway

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 3 of 3 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.9 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.7 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.5 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)