Motif ID: UCCCUUU

Z-value: 0.196


Mature miRNA associated with seed UCCCUUU:

NamemiRBase Accession
hsa-miR-204-5p MIMAT0000265
hsa-miR-211-5p MIMAT0000268



Activity profile for motif UCCCUUU.

activity profile for motif UCCCUUU


Sorted Z-values histogram for motif UCCCUUU

Sorted Z-values for motif UCCCUUU



Network of associatons between targets according to the STRING database.



First level regulatory network of UCCCUUU

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr12_+_4382917 0.388 ENST00000261254.3
 CCND2
cyclin D2
chr4_-_111119804 0.211 ENST00000394607.3
ENST00000302274.3
 ELOVL6

ELOVL fatty acid elongase 6

chr12_+_66217911 0.204 ENST00000403681.2
 HMGA2
high mobility group AT-hook 2
chr7_+_100797678 0.170 ENST00000337619.5
 AP1S1
adaptor-related protein complex 1, sigma 1 subunit
chr1_-_154943212 0.161 ENST00000368445.5
ENST00000448116.2
ENST00000368449.4
 SHC1


SHC (Src homology 2 domain containing) transforming protein 1


chr5_-_127873659 0.147 ENST00000262464.4
 FBN2
fibrillin 2
chr16_+_46918235 0.135 ENST00000340124.4
 GPT2
glutamic pyruvate transaminase (alanine aminotransferase) 2
chr13_+_98605902 0.123 ENST00000460070.1
ENST00000481455.1
ENST00000261574.5
ENST00000493281.1
ENST00000463157.1
ENST00000471898.1
ENST00000489058.1
ENST00000481689.1
 IPO5







importin 5







chr4_-_41750922 0.121 ENST00000226382.2
 PHOX2B
paired-like homeobox 2b
chr20_+_6748311 0.109 ENST00000378827.4
 BMP2
bone morphogenetic protein 2
chr22_-_37099555 0.107 ENST00000300105.6
 CACNG2
calcium channel, voltage-dependent, gamma subunit 2
chr1_-_39325431 0.101 ENST00000373001.3
 RRAGC
Ras-related GTP binding C
chr13_-_50510434 0.098 ENST00000361840.3
 SPRYD7
SPRY domain containing 7
chr6_+_160390102 0.091 ENST00000356956.1
 IGF2R
insulin-like growth factor 2 receptor
chr20_+_56884752 0.091 ENST00000244040.3
 RAB22A
RAB22A, member RAS oncogene family
chr22_-_42017021 0.086 ENST00000263256.6
 DESI1
desumoylating isopeptidase 1
chr9_+_4985228 0.085 ENST00000381652.3
 JAK2
Janus kinase 2
chr6_+_11094266 0.083 ENST00000416247.2
 SMIM13
small integral membrane protein 13
chr10_+_99400443 0.082 ENST00000370631.3
 PI4K2A
phosphatidylinositol 4-kinase type 2 alpha
chr1_+_90098606 0.081 ENST00000370454.4
 LRRC8C
leucine rich repeat containing 8 family, member C

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 26 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.4 GO:0071481 cellular response to X-ray(GO:0071481)
0.1 0.2 GO:0031052 mesodermal-endodermal cell signaling(GO:0003131) programmed DNA elimination(GO:0031049) chromosome breakage(GO:0031052) histone H2A-S139 phosphorylation(GO:0035978) positive regulation of cellular response to X-ray(GO:2000685)
0.0 0.2 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.1 GO:0002276 basophil activation involved in immune response(GO:0002276)
0.0 0.1 GO:0003358 noradrenergic neuron development(GO:0003358)
0.0 0.1 GO:0042853 L-alanine metabolic process(GO:0042851) L-alanine catabolic process(GO:0042853)
0.0 0.1 GO:0003133 BMP signaling pathway involved in heart induction(GO:0003130) endodermal-mesodermal cell signaling(GO:0003133) endodermal-mesodermal cell signaling involved in heart induction(GO:0003134) negative regulation of Wnt signaling pathway involved in heart development(GO:0003308) embryonic heart tube anterior/posterior pattern specification(GO:0035054)
0.0 0.1 GO:0097051 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200) establishment of protein localization to endoplasmic reticulum membrane(GO:0097051)
0.0 0.1 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.0 0.1 GO:0061386 closure of optic fissure(GO:0061386)
0.0 0.1 GO:0002514 B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663)
0.0 0.1 GO:0045226 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.0 0.1 GO:0071109 superior temporal gyrus development(GO:0071109)
0.0 0.1 GO:1902728 mineralocorticoid receptor signaling pathway(GO:0031959) positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728)
0.0 0.1 GO:0036510 trimming of terminal mannose on C branch(GO:0036510)
0.0 0.1 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.0 0.1 GO:1902954 regulation of early endosome to recycling endosome transport(GO:1902954)
0.0 0.1 GO:0071477 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.0 0.1 GO:1902044 regulation of Fas signaling pathway(GO:1902044)
0.0 0.1 GO:0022027 interkinetic nuclear migration(GO:0022027)

Gene overrepresentation in cellular_component category:

Showing 1 to 9 of 9 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 0.4 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.0 0.2 GO:0070435 Shc-EGFR complex(GO:0070435)
0.0 0.2 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.2 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.1 GO:0035838 growing cell tip(GO:0035838)
0.0 0.1 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.0 GO:0034681 integrin alpha11-beta1 complex(GO:0034681)
0.0 0.0 GO:0042565 RNA nuclear export complex(GO:0042565)
0.0 0.0 GO:0005896 interleukin-6 receptor complex(GO:0005896)

Gene overrepresentation in molecular_function category:

Showing 1 to 12 of 12 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 0.2 GO:0035501 MH1 domain binding(GO:0035501)
0.0 0.2 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.2 GO:0048408 epidermal growth factor binding(GO:0048408)
0.0 0.1 GO:0035651 AP-3 adaptor complex binding(GO:0035651)
0.0 0.1 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.0 0.1 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.0 GO:0019981 interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
0.0 0.0 GO:0004119 cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119)
0.0 0.0 GO:0090631 pre-miRNA transporter activity(GO:0090631)
0.0 0.0 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.0 GO:0061628 H3K27me3 modified histone binding(GO:0061628)

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 1 of 1 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.2 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression