Motif ID: UGGCACU

Z-value: 0.369





Activity profile for motif UGGCACU.

activity profile for motif UGGCACU


Sorted Z-values histogram for motif UGGCACU

Sorted Z-values for motif UGGCACU



Network of associatons between targets according to the STRING database.



First level regulatory network of UGGCACU

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_-_100238956 1.270 ENST00000231461.5
 ST8SIA4
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
chr3_+_160473996 0.763 ENST00000498165.1
 PPM1L
protein phosphatase, Mg2+/Mn2+ dependent, 1L
chr11_-_45687128 0.677 ENST00000308064.2
 CHST1
carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
chr9_+_4490394 0.675 ENST00000262352.3
 SLC1A1
solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
chr2_+_97481974 0.641 ENST00000377060.3
ENST00000305510.3
 CNNM3

cyclin M3

chrX_+_16964794 0.553 ENST00000357277.3
 REPS2
RALBP1 associated Eps domain containing 2
chr19_+_32896697 0.547 ENST00000586987.1
 DPY19L3
dpy-19-like 3 (C. elegans)
chr16_-_68482440 0.547 ENST00000219334.5
 SMPD3
sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)
chr5_+_76506706 0.541 ENST00000340978.3
ENST00000346042.3
ENST00000264917.5
ENST00000342343.4
ENST00000333194.4
 PDE8B




phosphodiesterase 8B




chr20_+_37434329 0.432 ENST00000299824.1
ENST00000373331.2
 PPP1R16B

protein phosphatase 1, regulatory subunit 16B

chr19_-_14316980 0.413 ENST00000361434.3
ENST00000340736.6
 LPHN1

latrophilin 1

chr3_-_66551351 0.404 ENST00000273261.3
 LRIG1
leucine-rich repeats and immunoglobulin-like domains 1
chr1_+_118148556 0.401 ENST00000369448.3
 FAM46C
family with sequence similarity 46, member C
chrX_+_9431324 0.399 ENST00000407597.2
ENST00000424279.1
ENST00000536365.1
ENST00000441088.1
ENST00000380961.1
ENST00000415293.1
 TBL1X





transducin (beta)-like 1X-linked





chr1_-_169863016 0.379 ENST00000367772.4
ENST00000367771.6
 SCYL3

SCY1-like 3 (S. cerevisiae)

chr10_+_72164135 0.368 ENST00000373218.4
 EIF4EBP2
eukaryotic translation initiation factor 4E binding protein 2
chr9_-_3525968 0.359 ENST00000382004.3
ENST00000302303.1
ENST00000449190.1
 RFX3


regulatory factor X, 3 (influences HLA class II expression)


chr8_+_120885949 0.313 ENST00000523492.1
ENST00000286234.5
 DEPTOR

DEP domain containing MTOR-interacting protein

chr17_+_48172639 0.312 ENST00000503176.1
ENST00000503614.1
 PDK2

pyruvate dehydrogenase kinase, isozyme 2

chr7_+_107301065 0.311 ENST00000265715.3
 SLC26A4
solute carrier family 26 (anion exchanger), member 4

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 70 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.2 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.1 0.7 GO:0070779 sulfur amino acid transport(GO:0000101) D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.7 GO:0006012 galactose metabolic process(GO:0006012)
0.1 0.5 GO:0018103 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.0 0.5 GO:0006685 sphingomyelin catabolic process(GO:0006685) positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.0 0.5 GO:0006198 cAMP catabolic process(GO:0006198)
0.1 0.4 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.1 0.4 GO:0002071 glandular epithelial cell maturation(GO:0002071) type B pancreatic cell maturation(GO:0072560)
0.1 0.4 GO:0032474 otolith morphogenesis(GO:0032474)
0.1 0.3 GO:0071106 coenzyme A transport(GO:0015880) coenzyme A transmembrane transport(GO:0035349) adenosine 3',5'-bisphosphate transmembrane transport(GO:0071106) AMP transport(GO:0080121)
0.1 0.3 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) positive regulation of NK T cell differentiation(GO:0051138) germline stem cell asymmetric division(GO:0098728)
0.0 0.3 GO:0032380 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.0 0.3 GO:0001757 somite specification(GO:0001757)
0.0 0.3 GO:0015705 iodide transport(GO:0015705)
0.0 0.3 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.3 GO:0042659 regulation of cell fate specification(GO:0042659)
0.0 0.3 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.0 0.3 GO:0045792 negative regulation of cell size(GO:0045792)
0.1 0.2 GO:1903410 lysine import(GO:0034226) L-lysine import(GO:0061461) L-lysine import into cell(GO:1903410)
0.1 0.2 GO:0035669 TRAM-dependent toll-like receptor signaling pathway(GO:0035668) TRAM-dependent toll-like receptor 4 signaling pathway(GO:0035669)

Gene overrepresentation in cellular_component category:

Showing 1 to 17 of 17 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 0.6 GO:0000137 Golgi cis cisterna(GO:0000137)
0.1 0.5 GO:0044294 dendritic growth cone(GO:0044294)
0.1 0.3 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0 0.2 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.2 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.2 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.2 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.1 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.0 0.1 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.0 0.1 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.0 0.1 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0 0.1 GO:0031213 RSF complex(GO:0031213)
0.0 0.1 GO:0033503 HULC complex(GO:0033503)
0.0 0.1 GO:0044308 axonal spine(GO:0044308)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.0 GO:0018444 translation release factor complex(GO:0018444)
0.0 0.0 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 43 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 1.3 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 0.7 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.1 0.7 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.5 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.5 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.5 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.4 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 0.3 GO:0015228 coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
0.1 0.3 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 0.3 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.0 0.3 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.3 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 0.2 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.1 0.2 GO:0005289 high-affinity basic amino acid transmembrane transporter activity(GO:0005287) high-affinity arginine transmembrane transporter activity(GO:0005289) high-affinity lysine transmembrane transporter activity(GO:0005292)
0.0 0.2 GO:0097363 protein N-acetylglucosaminyltransferase activity(GO:0016262) protein O-GlcNAc transferase activity(GO:0097363)
0.0 0.2 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.0 0.2 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.0 0.2 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.0 0.2 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.2 GO:0031826 type 2A serotonin receptor binding(GO:0031826)

Gene overrepresentation in C2:CP category:

Showing 1 to 2 of 2 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.3 PID_MET_PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.2 PID_CERAMIDE_PATHWAY Ceramide signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 12 of 12 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.1 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.8 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.7 REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.6 REACTOME_KERATAN_SULFATE_BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 0.4 REACTOME_SIGNALING_BY_EGFR_IN_CANCER Genes involved in Signaling by EGFR in Cancer
0.0 0.4 REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.3 REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.2 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.2 REACTOME_REGULATED_PROTEOLYSIS_OF_P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 0.1 REACTOME_GRB2_SOS_PROVIDES_LINKAGE_TO_MAPK_SIGNALING_FOR_INTERGRINS_ Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.1 REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.1 REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_RAS Genes involved in CREB phosphorylation through the activation of Ras