Motif ID: UUGGCAC

Z-value: 0.373


Mature miRNA associated with seed UUGGCAC:

NamemiRBase Accession
hsa-miR-1271-5p MIMAT0005796
hsa-miR-96-5p MIMAT0000095



Activity profile for motif UUGGCAC.

activity profile for motif UUGGCAC


Sorted Z-values histogram for motif UUGGCAC

Sorted Z-values for motif UUGGCAC



Network of associatons between targets according to the STRING database.



First level regulatory network of UUGGCAC

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_-_20812690 1.057 ENST00000375078.3
 CAMK2N1
calcium/calmodulin-dependent protein kinase II inhibitor 1
chr22_+_30792846 0.966 ENST00000312932.9
ENST00000428195.1
 SEC14L2

SEC14-like 2 (S. cerevisiae)

chr12_+_4382917 0.890 ENST00000261254.3
 CCND2
cyclin D2
chr12_-_57630873 0.834 ENST00000556732.1
 NDUFA4L2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
chrX_+_64887512 0.718 ENST00000360270.5
 MSN
moesin
chr19_+_54371114 0.681 ENST00000448420.1
ENST00000439000.1
ENST00000391770.4
ENST00000391771.1
 MYADM



myeloid-associated differentiation marker



chrX_-_106959631 0.625 ENST00000486554.1
ENST00000372390.4
 TSC22D3

TSC22 domain family, member 3

chr21_-_44846999 0.591 ENST00000270162.6
 SIK1
salt-inducible kinase 1
chr7_+_2671568 0.582 ENST00000258796.7
 TTYH3
tweety family member 3
chr17_-_41174424 0.565 ENST00000355653.3
 VAT1
vesicle amine transport 1
chr19_-_49015050 0.557 ENST00000600059.1
 LMTK3
lemur tyrosine kinase 3
chr20_+_361261 0.554 ENST00000217233.3
 TRIB3
tribbles pseudokinase 3
chr2_-_235405679 0.531 ENST00000390645.2
 ARL4C
ADP-ribosylation factor-like 4C
chr20_-_56284816 0.523 ENST00000395819.3
ENST00000341744.3
 PMEPA1

prostate transmembrane protein, androgen induced 1

chr1_-_154943212 0.512 ENST00000368445.5
ENST00000448116.2
ENST00000368449.4
 SHC1


SHC (Src homology 2 domain containing) transforming protein 1


chr7_+_43622664 0.490 ENST00000319357.5
 STK17A
serine/threonine kinase 17a
chrX_-_107681633 0.469 ENST00000394872.2
ENST00000334504.7
 COL4A6

collagen, type IV, alpha 6

chr17_+_41476327 0.448 ENST00000320033.4
 ARL4D
ADP-ribosylation factor-like 4D
chr15_-_34628951 0.447 ENST00000397707.2
ENST00000560611.1
 SLC12A6

solute carrier family 12 (potassium/chloride transporter), member 6

chr1_+_230202936 0.441 ENST00000366672.4
 GALNT2
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 150 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.9 GO:0045540 regulation of cholesterol biosynthetic process(GO:0045540)
0.1 0.8 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.0 0.8 GO:0071481 cellular response to X-ray(GO:0071481)
0.0 0.8 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.0 0.8 GO:0032456 endocytic recycling(GO:0032456)
0.2 0.7 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.1 0.7 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
0.0 0.7 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.1 0.6 GO:0022614 membrane to membrane docking(GO:0022614)
0.1 0.6 GO:0038026 reelin-mediated signaling pathway(GO:0038026)
0.1 0.6 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.6 GO:0070831 basement membrane assembly(GO:0070831)
0.1 0.5 GO:0044805 late nucleophagy(GO:0044805)
0.0 0.5 GO:0021859 pyramidal neuron differentiation(GO:0021859) pyramidal neuron development(GO:0021860)
0.0 0.5 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.0 0.5 GO:0007176 regulation of epidermal growth factor-activated receptor activity(GO:0007176)
0.1 0.4 GO:0033242 regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
0.1 0.4 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
0.1 0.4 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.1 0.4 GO:0071477 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 57 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.2 GO:0055038 recycling endosome membrane(GO:0055038)
0.1 0.9 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.0 0.8 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.8 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.7 GO:0031143 pseudopodium(GO:0031143)
0.1 0.5 GO:0070435 Shc-EGFR complex(GO:0070435)
0.1 0.5 GO:0005587 collagen type IV trimer(GO:0005587)
0.0 0.5 GO:0031209 SCAR complex(GO:0031209)
0.0 0.5 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.1 0.4 GO:0043259 laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259) laminin-11 complex(GO:0043260)
0.1 0.4 GO:0045160 myosin I complex(GO:0045160)
0.1 0.4 GO:0070695 FHF complex(GO:0070695)
0.0 0.4 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.4 GO:0097228 sperm principal piece(GO:0097228)
0.1 0.3 GO:1990032 parallel fiber(GO:1990032)
0.1 0.3 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
0.0 0.3 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.3 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.3 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 0.3 GO:0042588 zymogen granule(GO:0042588)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 76 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.3 GO:0003725 double-stranded RNA binding(GO:0003725)
0.4 1.1 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.2 1.0 GO:0008431 vitamin E binding(GO:0008431)
0.0 0.9 GO:0019003 GDP binding(GO:0019003)
0.0 0.8 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.7 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 0.6 GO:0043426 MRF binding(GO:0043426)
0.0 0.6 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.6 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.1 0.5 GO:0048408 epidermal growth factor binding(GO:0048408)
0.0 0.5 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.5 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.1 0.4 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
0.0 0.4 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.4 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.4 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.4 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.1 0.3 GO:0032145 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
0.1 0.3 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.0 0.3 GO:0035662 Toll-like receptor 4 binding(GO:0035662)

Gene overrepresentation in C2:CP category:

Showing 1 to 14 of 14 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.4 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 1.0 PID_ECADHERIN_NASCENT_AJ_PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 1.0 PID_IL2_STAT5_PATHWAY IL2 signaling events mediated by STAT5
0.0 0.9 SA_TRKA_RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.8 PID_NECTIN_PATHWAY Nectin adhesion pathway
0.0 0.8 PID_RHOA_PATHWAY RhoA signaling pathway
0.0 0.7 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.0 0.5 PID_S1P_S1P4_PATHWAY S1P4 pathway
0.0 0.5 PID_INTEGRIN5_PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.4 PID_INTEGRIN4_PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.4 PID_ANTHRAX_PATHWAY Cellular roles of Anthrax toxin
0.0 0.3 PID_PDGFRA_PATHWAY PDGFR-alpha signaling pathway
0.0 0.2 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network
0.0 0.2 SIG_IL4RECEPTOR_IN_B_LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 22 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.9 REACTOME_G1_PHASE Genes involved in G1 Phase
0.0 0.8 REACTOME_SIGNAL_ATTENUATION Genes involved in Signal attenuation
0.0 0.7 REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1 0.6 REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.6 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.6 REACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.5 REACTOME_RECYCLING_PATHWAY_OF_L1 Genes involved in Recycling pathway of L1
0.0 0.4 REACTOME_GRB2_SOS_PROVIDES_LINKAGE_TO_MAPK_SIGNALING_FOR_INTERGRINS_ Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.4 REACTOME_RAP1_SIGNALLING Genes involved in Rap1 signalling
0.1 0.3 REACTOME_GASTRIN_CREB_SIGNALLING_PATHWAY_VIA_PKC_AND_MAPK Genes involved in Gastrin-CREB signalling pathway via PKC and MAPK
0.0 0.3 REACTOME_SHC_RELATED_EVENTS Genes involved in SHC-related events
0.0 0.3 REACTOME_CALNEXIN_CALRETICULIN_CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.3 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.0 0.3 REACTOME_SIGNALING_BY_CONSTITUTIVELY_ACTIVE_EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.2 REACTOME_ADENYLATE_CYCLASE_INHIBITORY_PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 0.2 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.2 REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.2 REACTOME_REGULATION_OF_SIGNALING_BY_CBL Genes involved in Regulation of signaling by CBL
0.0 0.2 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.1 REACTOME_DSCAM_INTERACTIONS Genes involved in DSCAM interactions