Motif ID: VAX2_RHOXF2

Z-value: 0.391

Transcription factors associated with VAX2_RHOXF2:

Gene SymbolEntrez IDGene Name
RHOXF2 ENSG00000131721.4 RHOXF2
VAX2 ENSG00000116035.2 VAX2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
VAX2hg19_v2_chr2_+_71127699_711277440.183.9e-01Click!
RHOXF2hg19_v2_chrX_+_119292467_1192924670.067.9e-01Click!


Activity profile for motif VAX2_RHOXF2.

activity profile for motif VAX2_RHOXF2


Sorted Z-values histogram for motif VAX2_RHOXF2

Sorted Z-values for motif VAX2_RHOXF2



Network of associatons between targets according to the STRING database.



First level regulatory network of VAX2_RHOXF2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 154 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_-_152386732 0.777 ENST00000271835.3
 CRNN
cornulin
chr19_-_36001113 0.743 ENST00000434389.1
 DMKN
dermokine
chr8_-_101661887 0.716 ENST00000311812.2
 SNX31
sorting nexin 31
chr9_+_125133315 0.630 ENST00000223423.4
ENST00000362012.2
 PTGS1

prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)

chr16_-_30122717 0.569 ENST00000566613.1
 GDPD3
glycerophosphodiester phosphodiesterase domain containing 3
chr8_-_91095099 0.498 ENST00000265431.3
 CALB1
calbindin 1, 28kDa
chr1_+_62439037 0.470 ENST00000545929.1
 INADL
InaD-like (Drosophila)
chr4_-_69111401 0.423 ENST00000332644.5
 TMPRSS11B
transmembrane protease, serine 11B
chr14_+_56584414 0.391 ENST00000559044.1
 PELI2
pellino E3 ubiquitin protein ligase family member 2
chr11_-_5323226 0.377 ENST00000380224.1
 OR51B4
olfactory receptor, family 51, subfamily B, member 4
chr9_+_125132803 0.375 ENST00000540753.1
 PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr8_-_42623747 0.372 ENST00000534622.1
 CHRNA6
cholinergic receptor, nicotinic, alpha 6 (neuronal)
chr8_+_7783859 0.353 ENST00000400120.3
 ZNF705B
zinc finger protein 705B
chr17_-_40337470 0.350 ENST00000293330.1
 HCRT
hypocretin (orexin) neuropeptide precursor
chr11_+_33061543 0.293 ENST00000432887.1
ENST00000528898.1
ENST00000531632.2
 TCP11L1


t-complex 11, testis-specific-like 1


chr6_+_130339710 0.281 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
 L3MBTL3


l(3)mbt-like 3 (Drosophila)


chr1_-_211307404 0.280 ENST00000367007.4
 KCNH1
potassium voltage-gated channel, subfamily H (eag-related), member 1
chr15_-_89755034 0.258 ENST00000563254.1
 RLBP1
retinaldehyde binding protein 1
chr17_+_40610862 0.249 ENST00000393829.2
ENST00000546249.1
ENST00000537728.1
ENST00000264649.6
ENST00000585525.1
ENST00000343619.4
ENST00000544137.1
ENST00000589727.1
ENST00000587824.1
 ATP6V0A1








ATPase, H+ transporting, lysosomal V0 subunit a1








chr4_+_88896819 0.247 ENST00000237623.7
ENST00000395080.3
ENST00000508233.1
ENST00000360804.4
 SPP1



secreted phosphoprotein 1




Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 32 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.0 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.1 0.7 GO:1903575 cornified envelope assembly(GO:1903575)
0.0 0.7 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.1 0.5 GO:0035502 metanephric part of ureteric bud development(GO:0035502)
0.1 0.4 GO:0008063 Toll signaling pathway(GO:0008063)
0.1 0.3 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.0 0.3 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 0.3 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.3 GO:0006776 vitamin A metabolic process(GO:0006776)
0.1 0.2 GO:2000866 positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866)
0.0 0.2 GO:0007070 negative regulation of transcription during mitosis(GO:0007068) negative regulation of transcription from RNA polymerase II promoter during mitosis(GO:0007070)
0.0 0.2 GO:0090402 oncogene-induced cell senescence(GO:0090402)
0.0 0.2 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.2 GO:0015722 canalicular bile acid transport(GO:0015722)
0.0 0.2 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.0 0.2 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.2 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.2 GO:0048023 positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.0 0.2 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.1 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)

Gene overrepresentation in cellular_component category:

Showing 1 to 8 of 8 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.4 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.2 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.2 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.2 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.2 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.1 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.0 0.1 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.1 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 20 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 1.0 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.1 0.5 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.4 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.4 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.3 GO:0005502 11-cis retinal binding(GO:0005502)
0.0 0.3 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 0.2 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.0 0.2 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 0.2 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.2 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.1 GO:0033823 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
0.0 0.1 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 0.1 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0 0.1 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 0.1 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.1 GO:0004802 transketolase activity(GO:0004802)
0.0 0.1 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.1 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0 0.0 GO:0008281 sulfonylurea receptor activity(GO:0008281)

Gene overrepresentation in C2:CP category:

Showing 1 to 1 of 1 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.2 PID_ERB_GENOMIC_PATHWAY Validated nuclear estrogen receptor beta network

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 6 of 6 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.2 REACTOME_PHASE1_FUNCTIONALIZATION_OF_COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 0.6 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.0 0.4 REACTOME_IRAK1_RECRUITS_IKK_COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.4 REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.2 REACTOME_APOBEC3G_MEDIATED_RESISTANCE_TO_HIV1_INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.2 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins