Motif ID: VENTX

Z-value: 0.352


Transcription factors associated with VENTX:

Gene SymbolEntrez IDGene Name
VENTX ENSG00000151650.7 VENTX

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
VENTXhg19_v2_chr10_+_135050908_1350509080.058.2e-01Click!


Activity profile for motif VENTX.

activity profile for motif VENTX


Sorted Z-values histogram for motif VENTX

Sorted Z-values for motif VENTX



Network of associatons between targets according to the STRING database.



First level regulatory network of VENTX

PNG image of the network

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Top targets:


Showing 1 to 20 of 167 entries
PromoterScoreRefseqGene SymbolGene Name
chr16_-_67517716 0.535 ENST00000290953.2
 AGRP
agouti related protein homolog (mouse)
chr12_+_107712173 0.527 ENST00000280758.5
ENST00000420571.2
 BTBD11

BTB (POZ) domain containing 11

chrX_-_153602991 0.388 ENST00000369850.3
ENST00000422373.1
 FLNA

filamin A, alpha

chr12_-_89746173 0.349 ENST00000308385.6
 DUSP6
dual specificity phosphatase 6
chr1_+_203651937 0.334 ENST00000341360.2
 ATP2B4
ATPase, Ca++ transporting, plasma membrane 4
chr2_+_171034646 0.309 ENST00000409044.3
ENST00000408978.4
 MYO3B

myosin IIIB

chr4_+_86525299 0.294 ENST00000512201.1
 ARHGAP24
Rho GTPase activating protein 24
chr11_-_107729887 0.228 ENST00000525815.1
 SLC35F2
solute carrier family 35, member F2
chr6_+_34204642 0.218 ENST00000347617.6
ENST00000401473.3
ENST00000311487.5
ENST00000447654.1
ENST00000395004.3
 HMGA1




high mobility group AT-hook 1




chr22_+_46476192 0.217 ENST00000443490.1
 FLJ27365
hsa-mir-4763
chr11_+_35198118 0.211 ENST00000525211.1
ENST00000526000.1
ENST00000279452.6
ENST00000527889.1
 CD44



CD44 molecule (Indian blood group)



chr6_-_138820624 0.209 ENST00000343505.5
 NHSL1
NHS-like 1
chrX_+_130192318 0.207 ENST00000370922.1
 ARHGAP36
Rho GTPase activating protein 36
chr14_+_65171315 0.198 ENST00000394691.1
 PLEKHG3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr6_-_111927062 0.193 ENST00000359831.4
 TRAF3IP2
TRAF3 interacting protein 2
chr5_+_1225470 0.185 ENST00000324642.3
ENST00000296821.4
 SLC6A18

solute carrier family 6 (neutral amino acid transporter), member 18

chr6_-_66417107 0.180 ENST00000370621.3
ENST00000370618.3
ENST00000503581.1
ENST00000393380.2
 EYS



eyes shut homolog (Drosophila)



chr16_+_69984810 0.178 ENST00000393701.2
ENST00000568461.1
 CLEC18A

C-type lectin domain family 18, member A

chr18_+_59000815 0.174 ENST00000262717.4
 CDH20
cadherin 20, type 2
chr2_-_163008903 0.169 ENST00000418842.2
ENST00000375497.3
 GCG

glucagon


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 21 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 0.5 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.1 0.4 GO:0016479 negative regulation of transcription from RNA polymerase I promoter(GO:0016479)
0.0 0.4 GO:0048305 immunoglobulin secretion(GO:0048305)
0.1 0.3 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.1 0.3 GO:0033242 regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
0.1 0.2 GO:0060585 regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.0 0.2 GO:0090402 oncogene-induced cell senescence(GO:0090402)
0.0 0.2 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.0 0.2 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.0 0.2 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.2 GO:0030916 otic vesicle formation(GO:0030916)
0.0 0.2 GO:0097475 motor neuron migration(GO:0097475)
0.0 0.2 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.1 GO:0038188 cholecystokinin signaling pathway(GO:0038188)
0.0 0.1 GO:2000382 positive regulation of mesoderm development(GO:2000382)
0.0 0.1 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 0.1 GO:0050957 equilibrioception(GO:0050957)
0.0 0.1 GO:0042421 norepinephrine biosynthetic process(GO:0042421)
0.0 0.1 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.0 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)

Gene overrepresentation in cellular_component category:

Showing 1 to 7 of 7 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 0.4 GO:0031523 Myb complex(GO:0031523)
0.0 0.2 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.0 0.2 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.0 0.2 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.0 0.2 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.1 GO:0001674 female germ cell nucleus(GO:0001674)
0.0 0.1 GO:1990246 uniplex complex(GO:1990246)

Gene overrepresentation in molecular_function category:

Showing 1 to 13 of 13 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.6 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.5 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 0.4 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.1 0.3 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
0.0 0.3 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.2 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.0 0.2 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 0.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.2 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.1 GO:0005174 CD40 receptor binding(GO:0005174)
0.0 0.1 GO:0004951 cholecystokinin receptor activity(GO:0004951)
0.0 0.1 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.1 GO:0030021 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)

Gene overrepresentation in C2:CP category:

Showing 1 to 1 of 1 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.5 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 4 of 4 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.3 REACTOME_ERKS_ARE_INACTIVATED Genes involved in ERKs are inactivated
0.0 0.2 REACTOME_APOBEC3G_MEDIATED_RESISTANCE_TO_HIV1_INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.2 REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.1 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine