Motif ID: VSX1
Z-value: 0.833
Transcription factors associated with VSX1:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| VSX1 | ENSG00000100987.10 | VSX1 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| VSX1 | hg19_v2_chr20_-_25062767_25062779 | 0.05 | 8.0e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.5 | 1.5 | GO:1904668 | positive regulation of ubiquitin protein ligase activity(GO:1904668) |
| 0.4 | 1.6 | GO:0070426 | positive regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070426) positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070434) |
| 0.4 | 3.0 | GO:0018103 | protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406) |
| 0.3 | 3.4 | GO:0007288 | sperm axoneme assembly(GO:0007288) |
| 0.3 | 1.0 | GO:1904204 | regulation of skeletal muscle hypertrophy(GO:1904204) |
| 0.3 | 1.8 | GO:0046985 | positive regulation of hemoglobin biosynthetic process(GO:0046985) |
| 0.3 | 0.9 | GO:0019243 | methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727) |
| 0.2 | 1.2 | GO:1904764 | negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764) |
| 0.2 | 0.7 | GO:0030327 | prenylated protein catabolic process(GO:0030327) |
| 0.2 | 0.8 | GO:0071934 | thiamine transmembrane transport(GO:0071934) |
| 0.2 | 0.6 | GO:0071418 | cellular response to amine stimulus(GO:0071418) |
| 0.2 | 1.1 | GO:0007352 | zygotic specification of dorsal/ventral axis(GO:0007352) |
| 0.2 | 0.9 | GO:0000973 | posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973) |
| 0.2 | 0.6 | GO:1902361 | mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361) |
| 0.1 | 0.4 | GO:1903348 | positive regulation of bicellular tight junction assembly(GO:1903348) |
| 0.1 | 0.4 | GO:0006667 | sphinganine metabolic process(GO:0006667) |
| 0.1 | 0.4 | GO:0071106 | coenzyme A transport(GO:0015880) coenzyme A transmembrane transport(GO:0035349) adenosine 3',5'-bisphosphate transmembrane transport(GO:0071106) AMP transport(GO:0080121) |
| 0.1 | 0.4 | GO:1990737 | response to manganese-induced endoplasmic reticulum stress(GO:1990737) |
| 0.1 | 0.4 | GO:1903630 | regulation of aminoacyl-tRNA ligase activity(GO:1903630) |
| 0.1 | 0.8 | GO:0010748 | regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) |
| 0.1 | 0.4 | GO:0006434 | seryl-tRNA aminoacylation(GO:0006434) |
| 0.1 | 0.8 | GO:0061055 | myotome development(GO:0061055) |
| 0.1 | 0.4 | GO:1904247 | positive regulation of polynucleotide adenylyltransferase activity(GO:1904247) |
| 0.1 | 0.6 | GO:0060406 | positive regulation of penile erection(GO:0060406) |
| 0.1 | 0.4 | GO:0072334 | UDP-galactose transport(GO:0015785) UDP-galactose transmembrane transport(GO:0072334) |
| 0.1 | 0.7 | GO:0051684 | maintenance of Golgi location(GO:0051684) |
| 0.1 | 0.4 | GO:0035425 | autocrine signaling(GO:0035425) |
| 0.1 | 1.0 | GO:1901419 | regulation of response to alcohol(GO:1901419) |
| 0.1 | 0.3 | GO:1904933 | regulation of cell proliferation in midbrain(GO:1904933) |
| 0.1 | 0.7 | GO:1900113 | negative regulation of histone H3-K9 trimethylation(GO:1900113) |
| 0.1 | 0.3 | GO:0060823 | canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060823) |
| 0.1 | 3.8 | GO:0071801 | regulation of podosome assembly(GO:0071801) |
| 0.1 | 1.7 | GO:0016446 | somatic hypermutation of immunoglobulin genes(GO:0016446) |
| 0.1 | 0.3 | GO:0001207 | histone displacement(GO:0001207) positive regulation of transcription involved in meiotic cell cycle(GO:0051039) |
| 0.1 | 0.7 | GO:0061669 | spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814) |
| 0.1 | 0.3 | GO:0015783 | GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079) |
| 0.1 | 2.7 | GO:0061157 | mRNA destabilization(GO:0061157) |
| 0.1 | 0.8 | GO:0072383 | plus-end-directed vesicle transport along microtubule(GO:0072383) |
| 0.1 | 0.3 | GO:0001994 | norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994) |
| 0.1 | 0.2 | GO:0071139 | resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140) |
| 0.1 | 0.3 | GO:1902617 | response to fluoride(GO:1902617) |
| 0.1 | 0.3 | GO:0014886 | transition between slow and fast fiber(GO:0014886) |
| 0.1 | 1.8 | GO:0006825 | copper ion transport(GO:0006825) |
| 0.1 | 0.4 | GO:0019236 | response to pheromone(GO:0019236) |
| 0.1 | 7.3 | GO:1903955 | positive regulation of protein targeting to mitochondrion(GO:1903955) |
| 0.1 | 0.2 | GO:0014016 | neuroblast differentiation(GO:0014016) |
| 0.1 | 0.5 | GO:0060501 | positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501) |
| 0.1 | 1.0 | GO:0030277 | maintenance of gastrointestinal epithelium(GO:0030277) |
| 0.1 | 0.8 | GO:0098828 | positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828) |
| 0.1 | 1.0 | GO:0006086 | acetyl-CoA biosynthetic process from pyruvate(GO:0006086) |
| 0.1 | 1.3 | GO:0042789 | mRNA transcription from RNA polymerase II promoter(GO:0042789) |
| 0.1 | 1.1 | GO:1902894 | negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894) |
| 0.1 | 2.7 | GO:1902475 | neutral amino acid transport(GO:0015804) L-alpha-amino acid transmembrane transport(GO:1902475) |
| 0.1 | 0.3 | GO:0051697 | protein delipidation(GO:0051697) |
| 0.0 | 0.2 | GO:0031291 | Ran protein signal transduction(GO:0031291) |
| 0.0 | 0.3 | GO:0007258 | JUN phosphorylation(GO:0007258) |
| 0.0 | 0.1 | GO:0034182 | regulation of maintenance of sister chromatid cohesion(GO:0034091) regulation of maintenance of mitotic sister chromatid cohesion(GO:0034182) |
| 0.0 | 0.5 | GO:0048194 | Golgi vesicle budding(GO:0048194) |
| 0.0 | 0.2 | GO:2001168 | regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168) |
| 0.0 | 1.4 | GO:0000717 | nucleotide-excision repair, DNA duplex unwinding(GO:0000717) |
| 0.0 | 0.3 | GO:0060481 | lobar bronchus epithelium development(GO:0060481) |
| 0.0 | 0.2 | GO:0061743 | motor learning(GO:0061743) |
| 0.0 | 3.0 | GO:0016266 | O-glycan processing(GO:0016266) |
| 0.0 | 0.4 | GO:0031086 | nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087) |
| 0.0 | 0.4 | GO:0014827 | intestine smooth muscle contraction(GO:0014827) |
| 0.0 | 0.3 | GO:0010606 | positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606) |
| 0.0 | 0.1 | GO:0046338 | phosphatidylethanolamine catabolic process(GO:0046338) |
| 0.0 | 0.1 | GO:0048203 | vesicle targeting, trans-Golgi to endosome(GO:0048203) |
| 0.0 | 0.1 | GO:0017186 | peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186) |
| 0.0 | 0.8 | GO:0044126 | regulation of growth of symbiont in host(GO:0044126) |
| 0.0 | 0.1 | GO:0060434 | bronchus morphogenesis(GO:0060434) |
| 0.0 | 0.1 | GO:0035928 | rRNA import into mitochondrion(GO:0035928) |
| 0.0 | 0.7 | GO:0036158 | outer dynein arm assembly(GO:0036158) |
| 0.0 | 0.5 | GO:0006568 | tryptophan metabolic process(GO:0006568) |
| 0.0 | 1.0 | GO:0003341 | cilium movement(GO:0003341) |
| 0.0 | 0.4 | GO:0018206 | peptidyl-methionine modification(GO:0018206) |
| 0.0 | 0.6 | GO:0019852 | L-ascorbic acid metabolic process(GO:0019852) |
| 0.0 | 0.7 | GO:0001829 | trophectodermal cell differentiation(GO:0001829) |
| 0.0 | 0.4 | GO:0015693 | magnesium ion transport(GO:0015693) |
| 0.0 | 0.2 | GO:1902177 | positive regulation of sister chromatid cohesion(GO:0045876) positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902177) |
| 0.0 | 0.1 | GO:0010286 | heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370) |
| 0.0 | 0.8 | GO:0035338 | long-chain fatty-acyl-CoA biosynthetic process(GO:0035338) |
| 0.0 | 0.8 | GO:0035082 | axoneme assembly(GO:0035082) |
| 0.0 | 1.1 | GO:0006607 | NLS-bearing protein import into nucleus(GO:0006607) |
| 0.0 | 1.8 | GO:0006120 | mitochondrial electron transport, NADH to ubiquinone(GO:0006120) |
| 0.0 | 0.7 | GO:0016578 | histone deubiquitination(GO:0016578) |
| 0.0 | 0.1 | GO:0043353 | enucleate erythrocyte differentiation(GO:0043353) |
| 0.0 | 0.2 | GO:0000055 | ribosomal large subunit export from nucleus(GO:0000055) ribosomal small subunit export from nucleus(GO:0000056) |
| 0.0 | 0.2 | GO:0071394 | cellular response to testosterone stimulus(GO:0071394) |
| 0.0 | 0.5 | GO:0007171 | activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171) |
| 0.0 | 0.1 | GO:0009405 | pathogenesis(GO:0009405) |
| 0.0 | 0.2 | GO:0007042 | lysosomal lumen acidification(GO:0007042) |
| 0.0 | 0.3 | GO:2000042 | negative regulation of double-strand break repair via homologous recombination(GO:2000042) |
| 0.0 | 0.4 | GO:0070986 | left/right axis specification(GO:0070986) |
| 0.0 | 0.2 | GO:0070934 | CRD-mediated mRNA stabilization(GO:0070934) |
| 0.0 | 0.9 | GO:0035335 | peptidyl-tyrosine dephosphorylation(GO:0035335) |
| 0.0 | 0.2 | GO:0060770 | negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770) |
| 0.0 | 0.8 | GO:0007339 | binding of sperm to zona pellucida(GO:0007339) |
| 0.0 | 0.3 | GO:0043982 | histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982) |
| 0.0 | 0.4 | GO:0019372 | lipoxygenase pathway(GO:0019372) |
| 0.0 | 0.2 | GO:0006703 | estrogen biosynthetic process(GO:0006703) |
| 0.0 | 0.6 | GO:0006099 | tricarboxylic acid cycle(GO:0006099) |
| 0.0 | 0.1 | GO:0072299 | adrenal cortex development(GO:0035801) adrenal cortex formation(GO:0035802) negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302) |
| 0.0 | 0.1 | GO:0006933 | negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933) |
| 0.0 | 0.3 | GO:0071108 | protein K48-linked deubiquitination(GO:0071108) |
| 0.0 | 0.1 | GO:0016255 | attachment of GPI anchor to protein(GO:0016255) |
| 0.0 | 1.1 | GO:0018149 | peptide cross-linking(GO:0018149) |
| 0.0 | 0.4 | GO:0045947 | negative regulation of translational initiation(GO:0045947) |
| 0.0 | 0.2 | GO:0033197 | response to vitamin E(GO:0033197) |
| 0.0 | 0.2 | GO:0030150 | protein import into mitochondrial matrix(GO:0030150) |
| 0.0 | 0.2 | GO:0097034 | mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034) |
| 0.0 | 0.5 | GO:0060765 | regulation of androgen receptor signaling pathway(GO:0060765) |
| 0.0 | 0.6 | GO:0000083 | regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083) |
| 0.0 | 0.3 | GO:0090036 | regulation of protein kinase C signaling(GO:0090036) |
| 0.0 | 0.3 | GO:0048026 | positive regulation of mRNA splicing, via spliceosome(GO:0048026) |
| 0.0 | 0.2 | GO:0071578 | zinc II ion transmembrane import(GO:0071578) |
| 0.0 | 0.4 | GO:0006506 | GPI anchor biosynthetic process(GO:0006506) |
| 0.0 | 0.1 | GO:0016480 | negative regulation of transcription from RNA polymerase III promoter(GO:0016480) |
| 0.0 | 0.1 | GO:0006228 | UTP biosynthetic process(GO:0006228) |
| 0.0 | 0.4 | GO:0007214 | gamma-aminobutyric acid signaling pathway(GO:0007214) |
| 0.0 | 0.1 | GO:0019747 | regulation of isoprenoid metabolic process(GO:0019747) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 3.4 | GO:0002177 | manchette(GO:0002177) |
| 0.2 | 1.0 | GO:0005967 | mitochondrial pyruvate dehydrogenase complex(GO:0005967) |
| 0.2 | 1.7 | GO:0032389 | MutLalpha complex(GO:0032389) |
| 0.2 | 0.7 | GO:0097196 | Shu complex(GO:0097196) |
| 0.2 | 0.5 | GO:0034657 | GID complex(GO:0034657) |
| 0.2 | 1.2 | GO:0098575 | lumenal side of lysosomal membrane(GO:0098575) |
| 0.1 | 0.9 | GO:0044614 | nuclear pore cytoplasmic filaments(GO:0044614) |
| 0.1 | 0.6 | GO:0005726 | perichromatin fibrils(GO:0005726) |
| 0.1 | 0.3 | GO:1990923 | PET complex(GO:1990923) |
| 0.1 | 6.3 | GO:0009925 | basal plasma membrane(GO:0009925) |
| 0.1 | 0.5 | GO:0032444 | activin responsive factor complex(GO:0032444) |
| 0.1 | 0.7 | GO:0042567 | insulin-like growth factor ternary complex(GO:0042567) |
| 0.1 | 1.4 | GO:0000109 | nucleotide-excision repair complex(GO:0000109) |
| 0.1 | 0.6 | GO:0017059 | serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211) |
| 0.1 | 0.8 | GO:0045252 | oxoglutarate dehydrogenase complex(GO:0045252) |
| 0.1 | 1.2 | GO:0034709 | methylosome(GO:0034709) |
| 0.1 | 0.7 | GO:0036157 | outer dynein arm(GO:0036157) |
| 0.1 | 0.7 | GO:0070776 | H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776) |
| 0.1 | 5.0 | GO:0005871 | kinesin complex(GO:0005871) |
| 0.1 | 0.2 | GO:0035061 | interchromatin granule(GO:0035061) |
| 0.0 | 0.7 | GO:0000124 | SAGA complex(GO:0000124) |
| 0.0 | 0.7 | GO:0031616 | spindle pole centrosome(GO:0031616) |
| 0.0 | 0.4 | GO:0030015 | CCR4-NOT core complex(GO:0030015) |
| 0.0 | 0.5 | GO:0005869 | dynactin complex(GO:0005869) |
| 0.0 | 0.2 | GO:0030934 | anchoring collagen complex(GO:0030934) |
| 0.0 | 0.2 | GO:0036398 | TCR signalosome(GO:0036398) |
| 0.0 | 0.4 | GO:0097470 | ribbon synapse(GO:0097470) |
| 0.0 | 0.2 | GO:0042406 | extrinsic component of endoplasmic reticulum membrane(GO:0042406) |
| 0.0 | 3.0 | GO:0005637 | nuclear inner membrane(GO:0005637) |
| 0.0 | 0.2 | GO:0033503 | HULC complex(GO:0033503) |
| 0.0 | 4.6 | GO:0005796 | Golgi lumen(GO:0005796) |
| 0.0 | 0.2 | GO:0070545 | PeBoW complex(GO:0070545) |
| 0.0 | 0.3 | GO:0031931 | TORC1 complex(GO:0031931) |
| 0.0 | 0.2 | GO:0005742 | mitochondrial outer membrane translocase complex(GO:0005742) |
| 0.0 | 0.1 | GO:0042765 | GPI-anchor transamidase complex(GO:0042765) |
| 0.0 | 1.0 | GO:0045121 | membrane raft(GO:0045121) membrane microdomain(GO:0098857) |
| 0.0 | 0.4 | GO:0042405 | nuclear inclusion body(GO:0042405) |
| 0.0 | 1.8 | GO:0045271 | mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271) |
| 0.0 | 0.7 | GO:0005721 | pericentric heterochromatin(GO:0005721) |
| 0.0 | 0.3 | GO:0072669 | tRNA-splicing ligase complex(GO:0072669) |
| 0.0 | 0.4 | GO:0060077 | inhibitory synapse(GO:0060077) |
| 0.0 | 0.2 | GO:0033063 | Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063) |
| 0.0 | 1.6 | GO:0016235 | aggresome(GO:0016235) |
| 0.0 | 0.1 | GO:0030991 | intraciliary transport particle A(GO:0030991) |
| 0.0 | 1.0 | GO:0016592 | mediator complex(GO:0016592) |
| 0.0 | 1.0 | GO:0030286 | dynein complex(GO:0030286) |
| 0.0 | 0.2 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
| 0.0 | 0.8 | GO:0032391 | photoreceptor connecting cilium(GO:0032391) |
| 0.0 | 0.2 | GO:0071204 | histone pre-mRNA 3'end processing complex(GO:0071204) |
| 0.0 | 0.0 | GO:0000939 | condensed chromosome inner kinetochore(GO:0000939) |
| 0.0 | 2.6 | GO:0071013 | catalytic step 2 spliceosome(GO:0071013) |
| 0.0 | 0.4 | GO:0017101 | aminoacyl-tRNA synthetase multienzyme complex(GO:0017101) |
| 0.0 | 0.3 | GO:0005689 | U12-type spliceosomal complex(GO:0005689) |
| 0.0 | 0.1 | GO:0070876 | SOSS complex(GO:0070876) |
| 0.0 | 0.4 | GO:0071564 | npBAF complex(GO:0071564) |
| 0.0 | 0.2 | GO:0002199 | zona pellucida receptor complex(GO:0002199) |
| 0.0 | 0.2 | GO:0097550 | transcriptional preinitiation complex(GO:0097550) |
| 0.0 | 0.7 | GO:0048786 | presynaptic active zone(GO:0048786) |
| 0.0 | 0.1 | GO:0000275 | mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) |
| 0.0 | 0.4 | GO:0031304 | intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305) |
| 0.0 | 0.2 | GO:0044233 | ER-mitochondrion membrane contact site(GO:0044233) |
| 0.0 | 0.2 | GO:0033093 | Weibel-Palade body(GO:0033093) |
| 0.0 | 0.2 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
| 0.0 | 0.1 | GO:0019773 | proteasome core complex, alpha-subunit complex(GO:0019773) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 0.9 | GO:0004416 | hydroxyacylglutathione hydrolase activity(GO:0004416) |
| 0.3 | 1.4 | GO:0032795 | heterotrimeric G-protein binding(GO:0032795) |
| 0.3 | 0.8 | GO:0015403 | thiamine uptake transmembrane transporter activity(GO:0015403) |
| 0.3 | 1.8 | GO:0044020 | histone methyltransferase activity (H4-R3 specific)(GO:0044020) |
| 0.3 | 2.8 | GO:0055131 | C3HC4-type RING finger domain binding(GO:0055131) |
| 0.2 | 1.7 | GO:0032138 | single base insertion or deletion binding(GO:0032138) |
| 0.2 | 1.0 | GO:0004740 | pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740) |
| 0.2 | 1.8 | GO:0016724 | ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724) |
| 0.2 | 0.6 | GO:0004852 | uroporphyrinogen-III synthase activity(GO:0004852) |
| 0.2 | 1.5 | GO:0010997 | anaphase-promoting complex binding(GO:0010997) |
| 0.2 | 1.0 | GO:0030197 | extracellular matrix constituent, lubricant activity(GO:0030197) |
| 0.1 | 0.4 | GO:0015228 | coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122) |
| 0.1 | 0.4 | GO:0004828 | serine-tRNA ligase activity(GO:0004828) |
| 0.1 | 0.7 | GO:0001025 | RNA polymerase III transcription factor binding(GO:0001025) |
| 0.1 | 0.4 | GO:0005459 | UDP-galactose transmembrane transporter activity(GO:0005459) |
| 0.1 | 0.5 | GO:0031685 | adenosine receptor binding(GO:0031685) |
| 0.1 | 0.6 | GO:0004758 | serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454) |
| 0.1 | 3.0 | GO:0000030 | mannosyltransferase activity(GO:0000030) |
| 0.1 | 0.4 | GO:0004694 | eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694) |
| 0.1 | 0.3 | GO:0004937 | alpha1-adrenergic receptor activity(GO:0004937) |
| 0.1 | 0.6 | GO:0004591 | oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591) |
| 0.1 | 0.4 | GO:0047066 | phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066) |
| 0.1 | 0.8 | GO:0008142 | oxysterol binding(GO:0008142) |
| 0.1 | 0.3 | GO:0005457 | GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080) |
| 0.1 | 0.7 | GO:0051864 | histone demethylase activity (H3-K36 specific)(GO:0051864) |
| 0.1 | 0.7 | GO:0016670 | oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670) |
| 0.1 | 0.6 | GO:0050833 | pyruvate transmembrane transporter activity(GO:0050833) |
| 0.1 | 1.7 | GO:0008569 | ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569) |
| 0.1 | 0.3 | GO:0050436 | microfibril binding(GO:0050436) |
| 0.1 | 0.7 | GO:0031995 | insulin-like growth factor II binding(GO:0031995) |
| 0.1 | 0.2 | GO:0004324 | ferredoxin-NADP+ reductase activity(GO:0004324) NADPH-adrenodoxin reductase activity(GO:0015039) oxidoreductase activity, acting on iron-sulfur proteins as donors(GO:0016730) oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor(GO:0016731) |
| 0.1 | 0.4 | GO:0046974 | histone methyltransferase activity (H3-K9 specific)(GO:0046974) |
| 0.1 | 2.7 | GO:0015175 | neutral amino acid transmembrane transporter activity(GO:0015175) |
| 0.1 | 3.4 | GO:0030544 | Hsp70 protein binding(GO:0030544) |
| 0.1 | 0.3 | GO:0016909 | JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909) |
| 0.1 | 0.6 | GO:0034056 | estrogen response element binding(GO:0034056) |
| 0.1 | 0.8 | GO:0031957 | very long-chain fatty acid-CoA ligase activity(GO:0031957) |
| 0.1 | 0.3 | GO:0061649 | ubiquitinated histone binding(GO:0061649) |
| 0.1 | 5.0 | GO:0003777 | microtubule motor activity(GO:0003777) |
| 0.0 | 0.2 | GO:0070404 | NADH binding(GO:0070404) |
| 0.0 | 0.3 | GO:0004719 | protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719) |
| 0.0 | 0.2 | GO:0003990 | acetylcholinesterase activity(GO:0003990) |
| 0.0 | 0.5 | GO:0030618 | transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618) |
| 0.0 | 0.1 | GO:0016603 | glutaminyl-peptide cyclotransferase activity(GO:0016603) |
| 0.0 | 0.4 | GO:0043176 | amine binding(GO:0043176) serotonin binding(GO:0051378) |
| 0.0 | 0.3 | GO:0005412 | glucose:sodium symporter activity(GO:0005412) |
| 0.0 | 1.2 | GO:0042288 | MHC class I protein binding(GO:0042288) |
| 0.0 | 0.9 | GO:0017056 | structural constituent of nuclear pore(GO:0017056) |
| 0.0 | 0.2 | GO:0023024 | MHC class I protein complex binding(GO:0023024) |
| 0.0 | 1.8 | GO:0050136 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
| 0.0 | 0.1 | GO:0003923 | GPI-anchor transamidase activity(GO:0003923) |
| 0.0 | 3.1 | GO:0003730 | mRNA 3'-UTR binding(GO:0003730) |
| 0.0 | 0.8 | GO:0070273 | phosphatidylinositol-4-phosphate binding(GO:0070273) |
| 0.0 | 0.2 | GO:0000285 | 1-phosphatidylinositol-3-phosphate 5-kinase activity(GO:0000285) |
| 0.0 | 0.2 | GO:0015288 | porin activity(GO:0015288) |
| 0.0 | 0.8 | GO:0071889 | 14-3-3 protein binding(GO:0071889) |
| 0.0 | 0.4 | GO:0035497 | cAMP response element binding(GO:0035497) |
| 0.0 | 0.1 | GO:0000994 | RNA polymerase III core binding(GO:0000994) |
| 0.0 | 0.1 | GO:0008240 | tripeptidyl-peptidase activity(GO:0008240) |
| 0.0 | 1.3 | GO:0001102 | RNA polymerase II activating transcription factor binding(GO:0001102) |
| 0.0 | 0.4 | GO:0015095 | magnesium ion transmembrane transporter activity(GO:0015095) |
| 0.0 | 0.2 | GO:0003810 | protein-glutamine gamma-glutamyltransferase activity(GO:0003810) |
| 0.0 | 0.8 | GO:0070577 | lysine-acetylated histone binding(GO:0070577) |
| 0.0 | 0.4 | GO:0050811 | GABA receptor binding(GO:0050811) |
| 0.0 | 0.3 | GO:0043996 | histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972) |
| 0.0 | 0.2 | GO:0008821 | crossover junction endodeoxyribonuclease activity(GO:0008821) |
| 0.0 | 0.4 | GO:0000900 | translation repressor activity, nucleic acid binding(GO:0000900) |
| 0.0 | 0.3 | GO:0003995 | acyl-CoA dehydrogenase activity(GO:0003995) |
| 0.0 | 0.3 | GO:0008429 | phosphatidylethanolamine binding(GO:0008429) |
| 0.0 | 0.6 | GO:0044183 | protein binding involved in protein folding(GO:0044183) |
| 0.0 | 0.6 | GO:0016676 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
| 0.0 | 0.7 | GO:0036002 | pre-mRNA binding(GO:0036002) |
| 0.0 | 0.3 | GO:0004551 | nucleotide diphosphatase activity(GO:0004551) |
| 0.0 | 0.3 | GO:0070016 | armadillo repeat domain binding(GO:0070016) |
| 0.0 | 0.1 | GO:0019862 | IgA binding(GO:0019862) |
| 0.0 | 0.9 | GO:0008138 | protein tyrosine/serine/threonine phosphatase activity(GO:0008138) |
| 0.0 | 0.3 | GO:0001223 | transcription coactivator binding(GO:0001223) |
| 0.0 | 0.1 | GO:0044729 | hemi-methylated DNA-binding(GO:0044729) |
| 0.0 | 0.3 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
| 0.0 | 0.4 | GO:0035035 | histone acetyltransferase binding(GO:0035035) |
| 0.0 | 0.1 | GO:0047499 | calcium-independent phospholipase A2 activity(GO:0047499) |
| 0.0 | 0.8 | GO:0030374 | ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.4 | PID_RANBP2_PATHWAY | Sumoylation by RanBP2 regulates transcriptional repression |
| 0.0 | 1.3 | PID_CD40_PATHWAY | CD40/CD40L signaling |
| 0.0 | 0.6 | PID_SMAD2_3PATHWAY | Regulation of cytoplasmic and nuclear SMAD2/3 signaling |
| 0.0 | 0.2 | PID_TCR_RAS_PATHWAY | Ras signaling in the CD4+ TCR pathway |
| 0.0 | 1.6 | PID_HIF1_TFPATHWAY | HIF-1-alpha transcription factor network |
| 0.0 | 3.5 | NABA_ECM_AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.0 | 0.9 | PID_ARF6_PATHWAY | Arf6 signaling events |
| 0.0 | 2.7 | PID_P53_DOWNSTREAM_PATHWAY | Direct p53 effectors |
| 0.0 | 1.5 | PID_SMAD2_3NUCLEAR_PATHWAY | Regulation of nuclear SMAD2/3 signaling |
| 0.0 | 0.8 | PID_FRA_PATHWAY | Validated transcriptional targets of AP1 family members Fra1 and Fra2 |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 4.6 | REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS | Genes involved in Termination of O-glycan biosynthesis |
| 0.1 | 4.2 | REACTOME_KINESINS | Genes involved in Kinesins |
| 0.1 | 1.0 | REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX | Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex |
| 0.1 | 2.0 | REACTOME_METAL_ION_SLC_TRANSPORTERS | Genes involved in Metal ion SLC transporters |
| 0.1 | 2.6 | REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE | Genes involved in Amino acid transport across the plasma membrane |
| 0.0 | 0.8 | REACTOME_SOS_MEDIATED_SIGNALLING | Genes involved in SOS-mediated signalling |
| 0.0 | 1.2 | REACTOME_GABA_SYNTHESIS_RELEASE_REUPTAKE_AND_DEGRADATION | Genes involved in GABA synthesis, release, reuptake and degradation |
| 0.0 | 0.4 | REACTOME_SEROTONIN_RECEPTORS | Genes involved in Serotonin receptors |
| 0.0 | 1.2 | REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |
| 0.0 | 4.7 | REACTOME_MRNA_SPLICING | Genes involved in mRNA Splicing |
| 0.0 | 0.7 | REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
| 0.0 | 0.5 | REACTOME_P2Y_RECEPTORS | Genes involved in P2Y receptors |
| 0.0 | 2.5 | REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL | Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
| 0.0 | 0.3 | REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS | Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers |
| 0.0 | 0.3 | REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS | Genes involved in Activation of the AP-1 family of transcription factors |
| 0.0 | 0.6 | REACTOME_METABOLISM_OF_PORPHYRINS | Genes involved in Metabolism of porphyrins |
| 0.0 | 0.5 | REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY | Genes involved in Post-chaperonin tubulin folding pathway |
| 0.0 | 1.3 | REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS | Genes involved in Metabolism of vitamins and cofactors |
| 0.0 | 0.5 | REACTOME_SIGNALING_BY_NODAL | Genes involved in Signaling by NODAL |
| 0.0 | 1.3 | REACTOME_RESPIRATORY_ELECTRON_TRANSPORT | Genes involved in Respiratory electron transport |
| 0.0 | 0.4 | REACTOME_ADP_SIGNALLING_THROUGH_P2RY12 | Genes involved in ADP signalling through P2Y purinoceptor 12 |
| 0.0 | 0.4 | REACTOME_SIGNALING_BY_HIPPO | Genes involved in Signaling by Hippo |
| 0.0 | 0.4 | REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION | Genes involved in Mitochondrial tRNA aminoacylation |
| 0.0 | 0.4 | REACTOME_REGULATION_OF_AMPK_ACTIVITY_VIA_LKB1 | Genes involved in Regulation of AMPK activity via LKB1 |
| 0.0 | 0.5 | REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS | Genes involved in Signaling by FGFR1 fusion mutants |
| 0.0 | 0.6 | REACTOME_PIP3_ACTIVATES_AKT_SIGNALING | Genes involved in PIP3 activates AKT signaling |
| 0.0 | 0.2 | REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN | Genes involved in Platelet Adhesion to exposed collagen |
