Motif ID: ZBTB12

Z-value: 0.683


Transcription factors associated with ZBTB12:

Gene SymbolEntrez IDGene Name
ZBTB12 ENSG00000204366.3 ZBTB12

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
ZBTB12hg19_v2_chr6_-_31869769_318698800.067.7e-01Click!


Activity profile for motif ZBTB12.

activity profile for motif ZBTB12


Sorted Z-values histogram for motif ZBTB12

Sorted Z-values for motif ZBTB12



Network of associatons between targets according to the STRING database.



First level regulatory network of ZBTB12

PNG image of the network

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Top targets:


Showing 1 to 20 of 161 entries
PromoterScoreRefseqGene SymbolGene Name
chr14_+_96949319 1.512 ENST00000554706.1
 AK7
adenylate kinase 7
chr10_+_23217006 1.226 ENST00000376528.4
ENST00000447081.1
 ARMC3

armadillo repeat containing 3

chr10_+_23216944 1.223 ENST00000298032.5
ENST00000409983.3
ENST00000409049.3
 ARMC3


armadillo repeat containing 3


chr9_+_127615733 1.219 ENST00000373574.1
 WDR38
WD repeat domain 38
chr1_+_78956651 1.022 ENST00000370757.3
ENST00000370756.3
 PTGFR

prostaglandin F receptor (FP)

chr17_+_11501748 0.803 ENST00000262442.4
ENST00000579828.1
 DNAH9

dynein, axonemal, heavy chain 9

chr12_-_58329819 0.779 ENST00000551421.1
 RP11-620J15.3
RP11-620J15.3
chr10_+_63422695 0.695 ENST00000330194.2
ENST00000389639.3
 C10orf107

chromosome 10 open reading frame 107

chr15_+_66797627 0.652 ENST00000565627.1
ENST00000564179.1
 ZWILCH

zwilch kinetochore protein

chr7_-_138347897 0.627 ENST00000288513.5
 SVOPL
SVOP-like
chr7_-_142247606 0.566 ENST00000390361.3
 TRBV7-3
T cell receptor beta variable 7-3
chr14_-_21270995 0.524 ENST00000555698.1
ENST00000397970.4
ENST00000340900.3
 RNASE1


ribonuclease, RNase A family, 1 (pancreatic)


chrX_+_41548259 0.491 ENST00000378138.5
 GPR34
G protein-coupled receptor 34
chr15_+_66797455 0.481 ENST00000446801.2
 ZWILCH
zwilch kinetochore protein
chr19_+_11457232 0.470 ENST00000587531.1
 CCDC159
coiled-coil domain containing 159
chr17_+_7517264 0.463 ENST00000572182.1
ENST00000574539.1
ENST00000576728.1
ENST00000575314.1
ENST00000570547.1
ENST00000572262.1
ENST00000576478.1
ENST00000593717.1
 SHBG






AC007421.1
sex hormone-binding globulin






AC007421.1
chr12_-_58329888 0.453 ENST00000546580.1
 RP11-620J15.3
RP11-620J15.3
chr12_-_123215306 0.411 ENST00000356987.2
ENST00000436083.2
 HCAR1

hydroxycarboxylic acid receptor 1

chr1_+_151009054 0.375 ENST00000295294.7
 BNIPL
BCL2/adenovirus E1B 19kD interacting protein like
chr1_+_61869748 0.371 ENST00000357977.5
 NFIA
nuclear factor I/A

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 34 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.5 GO:0015949 nucleobase-containing small molecule interconversion(GO:0015949)
0.1 1.0 GO:0071798 response to prostaglandin D(GO:0071798) cellular response to prostaglandin D stimulus(GO:0071799)
0.0 0.8 GO:0003341 cilium movement(GO:0003341)
0.1 0.7 GO:0040009 regulation of growth rate(GO:0040009)
0.0 0.5 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.5 GO:0030488 tRNA methylation(GO:0030488)
0.1 0.4 GO:0003172 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.0 0.4 GO:0001302 replicative cell aging(GO:0001302)
0.0 0.4 GO:0072189 ureter development(GO:0072189)
0.1 0.3 GO:0042214 terpene metabolic process(GO:0042214)
0.0 0.3 GO:0015747 urate transport(GO:0015747)
0.0 0.3 GO:0045475 locomotor rhythm(GO:0045475)
0.0 0.3 GO:0048311 mitochondrion distribution(GO:0048311)
0.1 0.2 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.0 0.2 GO:0090212 vitamin E metabolic process(GO:0042360) regulation of establishment of blood-brain barrier(GO:0090210) negative regulation of establishment of blood-brain barrier(GO:0090212)
0.0 0.2 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.2 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.2 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.2 GO:0015074 DNA integration(GO:0015074)
0.0 0.2 GO:0032930 complement receptor mediated signaling pathway(GO:0002430) positive regulation of superoxide anion generation(GO:0032930)

Gene overrepresentation in cellular_component category:

Showing 1 to 11 of 11 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 1.1 GO:1990423 RZZ complex(GO:1990423)
0.0 0.8 GO:0030286 dynein complex(GO:0030286)
0.0 0.3 GO:0032389 MutLalpha complex(GO:0032389)
0.0 0.3 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.2 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.0 0.2 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.0 0.2 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.2 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.2 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.1 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.0 0.1 GO:0030688 preribosome, small subunit precursor(GO:0030688)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 22 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 1.5 GO:0004127 cytidylate kinase activity(GO:0004127)
0.3 1.0 GO:0004958 prostaglandin F receptor activity(GO:0004958)
0.0 0.8 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.1 0.5 GO:0004522 ribonuclease A activity(GO:0004522)
0.1 0.5 GO:0005497 androgen binding(GO:0005497)
0.0 0.5 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.4 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.3 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.3 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.3 GO:0030983 mismatched DNA binding(GO:0030983)
0.1 0.2 GO:0005124 scavenger receptor binding(GO:0005124)
0.1 0.2 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.0 0.2 GO:0008431 vitamin E binding(GO:0008431)
0.0 0.2 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 0.2 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0 0.2 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.2 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.2 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.2 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.0 0.1 GO:0031826 type 2A serotonin receptor binding(GO:0031826)

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 6 of 6 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.0 REACTOME_PROSTANOID_LIGAND_RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.3 REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.3 REACTOME_REGULATION_OF_AMPK_ACTIVITY_VIA_LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.2 REACTOME_APOBEC3G_MEDIATED_RESISTANCE_TO_HIV1_INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.2 REACTOME_REVERSIBLE_HYDRATION_OF_CARBON_DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.2 REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex