Motif ID: ZBTB3

Z-value: 0.511


Transcription factors associated with ZBTB3:

Gene SymbolEntrez IDGene Name
ZBTB3 ENSG00000185670.7 ZBTB3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
ZBTB3hg19_v2_chr11_-_62521614_625216600.639.1e-04Click!


Activity profile for motif ZBTB3.

activity profile for motif ZBTB3


Sorted Z-values histogram for motif ZBTB3

Sorted Z-values for motif ZBTB3



Network of associatons between targets according to the STRING database.



First level regulatory network of ZBTB3

PNG image of the network

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Top targets:


Showing 1 to 20 of 105 entries
PromoterScoreRefseqGene SymbolGene Name
chrX_+_152240819 1.537 ENST00000535416.1
ENST00000421798.3
 PNMA6A
PNMA6C
paraneoplastic Ma antigen family member 6A
paraneoplastic Ma antigen family member 6C
chrX_+_152338301 1.529 ENST00000453825.2
 PNMA6A
paraneoplastic Ma antigen family member 6A
chr11_+_73661364 0.934 ENST00000339764.1
 DNAJB13
DnaJ (Hsp40) homolog, subfamily B, member 13
chr14_-_92413727 0.896 ENST00000267620.10
 FBLN5
fibulin 5
chr6_+_29274403 0.758 ENST00000377160.2
 OR14J1
olfactory receptor, family 14, subfamily J, member 1
chr5_+_76506706 0.736 ENST00000340978.3
ENST00000346042.3
ENST00000264917.5
ENST00000342343.4
ENST00000333194.4
 PDE8B




phosphodiesterase 8B




chr16_-_68406161 0.731 ENST00000568373.1
ENST00000563226.1
 SMPD3

sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)

chr6_-_46138676 0.718 ENST00000371383.2
ENST00000230565.3
 ENPP5

ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative)

chr14_-_92413353 0.716 ENST00000556154.1
 FBLN5
fibulin 5
chr14_-_92414055 0.716 ENST00000342058.4
 FBLN5
fibulin 5
chr2_-_154335300 0.642 ENST00000325926.3
 RPRM
reprimo, TP53 dependent G2 arrest mediator candidate
chr16_-_19896220 0.561 ENST00000562469.1
ENST00000300571.2
 GPRC5B

G protein-coupled receptor, family C, group 5, member B

chr19_+_49496705 0.507 ENST00000595090.1
 RUVBL2
RuvB-like AAA ATPase 2
chr1_+_211433275 0.505 ENST00000367005.4
 RCOR3
REST corepressor 3
chr7_+_23719749 0.445 ENST00000409192.3
ENST00000344962.4
ENST00000409653.1
ENST00000409994.3
 FAM221A



family with sequence similarity 221, member A



chr19_+_49496782 0.442 ENST00000601968.1
ENST00000596837.1
 RUVBL2

RuvB-like AAA ATPase 2

chr1_+_110036699 0.424 ENST00000496961.1
ENST00000533024.1
ENST00000310611.4
ENST00000527072.1
ENST00000420578.2
ENST00000528785.1
 CYB561D1





cytochrome b561 family, member D1





chr5_-_82969405 0.407 ENST00000510978.1
 HAPLN1
hyaluronan and proteoglycan link protein 1
chr1_+_110036728 0.403 ENST00000369868.3
ENST00000430195.2
 CYB561D1

cytochrome b561 family, member D1

chr17_-_17109579 0.399 ENST00000321560.3
 PLD6
phospholipase D family, member 6

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 32 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 2.3 GO:0048251 elastic fiber assembly(GO:0048251)
0.2 0.9 GO:0090202 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.2 0.9 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.1 0.7 GO:0006685 sphingomyelin catabolic process(GO:0006685) positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.0 0.7 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.6 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.0 0.4 GO:0010635 regulation of mitochondrial fusion(GO:0010635)
0.0 0.4 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 0.4 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0 0.4 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 0.3 GO:0003218 cardiac left ventricle formation(GO:0003218)
0.0 0.3 GO:0071028 nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.0 0.3 GO:0060742 epithelial cell differentiation involved in prostate gland development(GO:0060742)
0.0 0.3 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 0.3 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.1 0.2 GO:0035621 ER to Golgi ceramide transport(GO:0035621)
0.1 0.2 GO:0072156 distal tubule morphogenesis(GO:0072156) metanephric proximal tubule development(GO:0072237)
0.0 0.2 GO:1990502 dense core granule maturation(GO:1990502)
0.0 0.2 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.2 GO:0010248 establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)

Gene overrepresentation in cellular_component category:

Showing 1 to 7 of 7 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 2.3 GO:0071953 elastic fiber(GO:0071953)
0.1 0.9 GO:0097255 R2TP complex(GO:0097255)
0.1 0.7 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.3 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.2 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.1 GO:0036398 TCR signalosome(GO:0036398)
0.0 0.1 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)

Gene overrepresentation in molecular_function category:

Showing 1 to 19 of 19 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.3 GO:0005178 integrin binding(GO:0005178)
0.1 0.9 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.1 0.8 GO:0005549 odorant binding(GO:0005549)
0.1 0.7 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.7 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 0.4 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.0 0.4 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.3 GO:0034353 RNA pyrophosphohydrolase activity(GO:0034353)
0.0 0.3 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.3 GO:0099604 calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.0 0.2 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 0.2 GO:0097001 ceramide binding(GO:0097001)
0.0 0.2 GO:0034511 U3 snoRNA binding(GO:0034511)
0.0 0.2 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.1 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 0.1 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 0.1 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 0.1 GO:0046790 virion binding(GO:0046790)

Gene overrepresentation in C2:CP category:

Showing 1 to 1 of 1 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.9 PID_MYC_PATHWAY C-MYC pathway

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 2 of 2 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.9 REACTOME_EXTENSION_OF_TELOMERES Genes involved in Extension of Telomeres
0.0 0.7 REACTOME_GLYCOSPHINGOLIPID_METABOLISM Genes involved in Glycosphingolipid metabolism