Motif ID: ZBTB49

Z-value: 0.592


Transcription factors associated with ZBTB49:

Gene SymbolEntrez IDGene Name
ZBTB49 ENSG00000168826.11 ZBTB49

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
ZBTB49hg19_v2_chr4_+_4291924_4292011-0.341.0e-01Click!


Activity profile for motif ZBTB49.

activity profile for motif ZBTB49


Sorted Z-values histogram for motif ZBTB49

Sorted Z-values for motif ZBTB49



Network of associatons between targets according to the STRING database.



First level regulatory network of ZBTB49

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_-_51466681 4.977 ENST00000456750.2
 KLK6
kallikrein-related peptidase 6
chr2_+_95691445 3.346 ENST00000353004.3
ENST00000354078.3
ENST00000349807.3
 MAL


mal, T-cell differentiation protein


chr2_+_95691417 3.051 ENST00000309988.4
 MAL
mal, T-cell differentiation protein
chr15_+_90728145 2.849 ENST00000561085.1
ENST00000379122.3
ENST00000332496.6
 SEMA4B


sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B


chr10_-_90751038 1.547 ENST00000458159.1
ENST00000415557.1
ENST00000458208.1
 ACTA2


actin, alpha 2, smooth muscle, aorta


chr10_+_94352956 1.531 ENST00000260731.3
 KIF11
kinesin family member 11
chr15_+_75639773 1.245 ENST00000567657.1
 NEIL1
nei endonuclease VIII-like 1 (E. coli)
chrX_+_64887512 1.221 ENST00000360270.5
 MSN
moesin
chr3_-_196756646 1.201 ENST00000439320.1
ENST00000296351.4
ENST00000296350.5
 MFI2


antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5


chr22_-_37915247 1.103 ENST00000251973.5
 CARD10
caspase recruitment domain family, member 10
chr17_-_80009650 0.975 ENST00000310496.4
 RFNG
RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr14_+_35591858 0.955 ENST00000603544.1
 KIAA0391
KIAA0391
chr17_-_74582191 0.879 ENST00000225276.5
 ST6GALNAC2
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
chr11_+_117857063 0.860 ENST00000227752.3
ENST00000541785.1
ENST00000545409.1
 IL10RA


interleukin 10 receptor, alpha


chr1_-_110933663 0.815 ENST00000369781.4
ENST00000541986.1
ENST00000369779.4
 SLC16A4


solute carrier family 16, member 4


chr6_-_109777128 0.804 ENST00000358807.3
ENST00000358577.3
 MICAL1

microtubule associated monooxygenase, calponin and LIM domain containing 1

chr9_+_139553306 0.749 ENST00000371699.1
 EGFL7
EGF-like-domain, multiple 7
chr1_-_110933611 0.746 ENST00000472422.2
ENST00000437429.2
 SLC16A4

solute carrier family 16, member 4

chr8_-_82024290 0.735 ENST00000220597.4
 PAG1
phosphoprotein associated with glycosphingolipid microdomains 1
chr6_-_49604545 0.668 ENST00000371175.4
ENST00000229810.7
 RHAG

Rh-associated glycoprotein

chr3_-_51813009 0.632 ENST00000398780.3
 IQCF6
IQ motif containing F6
chr5_-_146833222 0.599 ENST00000534907.1
 DPYSL3
dihydropyrimidinase-like 3
chr3_-_49055991 0.588 ENST00000441576.2
ENST00000420952.2
ENST00000341949.4
ENST00000395462.4
 DALRD3



DALR anticodon binding domain containing 3



chr22_-_20255212 0.574 ENST00000416372.1
 RTN4R
reticulon 4 receptor
chr14_+_35591735 0.551 ENST00000604948.1
ENST00000605201.1
ENST00000250377.7
ENST00000321130.10
ENST00000534898.4
 KIAA0391




KIAA0391




chr2_+_89890533 0.542 ENST00000429992.2
 IGKV2D-40
immunoglobulin kappa variable 2D-40
chr14_+_35591928 0.517 ENST00000605870.1
ENST00000557404.3
 KIAA0391

KIAA0391

chr3_-_172428959 0.510 ENST00000475381.1
ENST00000538775.1
ENST00000273512.3
ENST00000543711.1
 NCEH1



neutral cholesterol ester hydrolase 1



chr6_-_153452356 0.507 ENST00000206262.1
 RGS17
regulator of G-protein signaling 17
chr22_-_20256054 0.495 ENST00000043402.7
 RTN4R
reticulon 4 receptor
chr14_-_74485960 0.463 ENST00000556242.1
ENST00000334696.6
 ENTPD5

ectonucleoside triphosphate diphosphohydrolase 5

chr22_-_19166343 0.450 ENST00000215882.5
 SLC25A1
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr5_+_154237778 0.436 ENST00000523698.1
ENST00000517876.1
ENST00000520472.1
 CNOT8


CCR4-NOT transcription complex, subunit 8


chr19_+_17862274 0.434 ENST00000596536.1
ENST00000593870.1
ENST00000598086.1
ENST00000598932.1
ENST00000595023.1
ENST00000594068.1
ENST00000596507.1
ENST00000595033.1
ENST00000597718.1
 FCHO1








FCH domain only 1








chr9_-_123676827 0.432 ENST00000546084.1
 TRAF1
TNF receptor-associated factor 1
chr8_+_95653302 0.432 ENST00000423620.2
ENST00000433389.2
 ESRP1

epithelial splicing regulatory protein 1

chr11_-_2950642 0.408 ENST00000314222.4
 PHLDA2
pleckstrin homology-like domain, family A, member 2
chr11_+_4116005 0.390 ENST00000300738.5
 RRM1
ribonucleotide reductase M1
chr2_+_234160217 0.384 ENST00000392017.4
ENST00000347464.5
ENST00000444735.1
ENST00000373525.5
ENST00000419681.1
 ATG16L1




autophagy related 16-like 1 (S. cerevisiae)




chrX_-_131623874 0.375 ENST00000436215.1
 MBNL3
muscleblind-like splicing regulator 3
chr6_-_43655511 0.364 ENST00000372133.3
ENST00000372116.1
ENST00000427312.1
 MRPS18A


mitochondrial ribosomal protein S18A


chr11_+_4116054 0.357 ENST00000423050.2
 RRM1
ribonucleotide reductase M1
chr19_-_59070239 0.354 ENST00000595957.1
ENST00000253023.3
 UBE2M

ubiquitin-conjugating enzyme E2M

chr2_+_234160340 0.339 ENST00000417017.1
ENST00000392020.4
ENST00000392018.1
 ATG16L1


autophagy related 16-like 1 (S. cerevisiae)


chr20_-_32700075 0.338 ENST00000374980.2
 EIF2S2
eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa
chr8_-_16043780 0.304 ENST00000445506.2
 MSR1
macrophage scavenger receptor 1
chr10_+_81466084 0.294 ENST00000342531.2
 NUTM2B
NUT family member 2B
chr4_-_2243839 0.293 ENST00000511885.2
ENST00000506763.1
ENST00000514395.1
ENST00000502440.1
ENST00000243706.4
ENST00000443786.2
 POLN
HAUS3




polymerase (DNA directed) nu
HAUS augmin-like complex, subunit 3




chr10_+_90750493 0.289 ENST00000357339.2
ENST00000355279.2
 FAS

Fas cell surface death receptor

chr10_+_64893039 0.282 ENST00000277746.6
ENST00000435510.2
 NRBF2

nuclear receptor binding factor 2

chr10_-_46641003 0.262 ENST00000395721.2
ENST00000374218.2
ENST00000395725.3
ENST00000374346.3
ENST00000417004.1
 PTPN20A




protein tyrosine phosphatase, non-receptor type 20A




chr20_-_25320367 0.255 ENST00000450393.1
ENST00000491682.1
 ABHD12

abhydrolase domain containing 12

chrX_+_30265256 0.250 ENST00000397548.2
 MAGEB1
melanoma antigen family B, 1
chr3_+_196594727 0.248 ENST00000445299.2
ENST00000323460.5
ENST00000419026.1
 SENP5


SUMO1/sentrin specific peptidase 5


chr7_-_44613494 0.242 ENST00000431640.1
ENST00000258772.5
 DDX56

DEAD (Asp-Glu-Ala-Asp) box helicase 56

chr6_+_53659746 0.242 ENST00000370888.1
 LRRC1
leucine rich repeat containing 1
chr16_+_81069433 0.238 ENST00000299575.4
 ATMIN
ATM interactor
chr12_+_104324112 0.233 ENST00000299767.5
 HSP90B1
heat shock protein 90kDa beta (Grp94), member 1
chr20_+_1115821 0.222 ENST00000435720.1
 PSMF1
proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
chr17_+_80009741 0.216 ENST00000578552.1
ENST00000320548.4
ENST00000581578.1
ENST00000583885.1
ENST00000583641.1
ENST00000581418.1
ENST00000355130.2
ENST00000306823.6
ENST00000392358.2
 GPS1








G protein pathway suppressor 1








chr19_-_4182530 0.205 ENST00000601571.1
ENST00000601488.1
ENST00000305232.6
ENST00000381935.3
ENST00000337491.2
 SIRT6




sirtuin 6




chr3_-_196242233 0.198 ENST00000397537.2
 SMCO1
single-pass membrane protein with coiled-coil domains 1
chr22_-_42017021 0.196 ENST00000263256.6
 DESI1
desumoylating isopeptidase 1
chr17_+_74734052 0.192 ENST00000590514.1
 MFSD11
major facilitator superfamily domain containing 11
chrX_+_52780318 0.190 ENST00000375515.3
ENST00000276049.6
 SSX2B

synovial sarcoma, X breakpoint 2B

chr3_+_52232102 0.177 ENST00000469224.1
ENST00000394965.2
ENST00000310271.2
ENST00000484952.1
 ALAS1



aminolevulinate, delta-, synthase 1



chr8_-_99129384 0.173 ENST00000521560.1
ENST00000254878.3
 HRSP12

heat-responsive protein 12

chrX_+_151903253 0.172 ENST00000452779.2
ENST00000370291.2
 CSAG1

chondrosarcoma associated gene 1

chr5_-_77590480 0.166 ENST00000519295.1
ENST00000255194.6
 AP3B1

adaptor-related protein complex 3, beta 1 subunit

chr15_-_55489097 0.165 ENST00000260443.4
 RSL24D1
ribosomal L24 domain containing 1
chr19_-_42894420 0.156 ENST00000597255.1
ENST00000222032.5
 CNFN

cornifelin

chr11_+_63993738 0.147 ENST00000441250.2
ENST00000279206.3
 NUDT22

nudix (nucleoside diphosphate linked moiety X)-type motif 22

chr5_+_154238096 0.142 ENST00000517568.1
ENST00000524105.1
ENST00000285896.6
 CNOT8


CCR4-NOT transcription complex, subunit 8


chr2_-_48982708 0.132 ENST00000428232.1
ENST00000405626.1
ENST00000294954.7
 LHCGR


luteinizing hormone/choriogonadotropin receptor


chr20_+_33134619 0.121 ENST00000374837.3
 MAP1LC3A
microtubule-associated protein 1 light chain 3 alpha
chr1_-_36863481 0.113 ENST00000315732.2
 LSM10
LSM10, U7 small nuclear RNA associated
chr8_-_99129338 0.108 ENST00000520507.1
 HRSP12
heat-responsive protein 12
chr18_-_11148587 0.107 ENST00000302079.6
ENST00000580640.1
ENST00000503781.3
 PIEZO2


piezo-type mechanosensitive ion channel component 2


chr16_+_28722684 0.103 ENST00000331666.6
ENST00000395587.1
ENST00000569690.1
ENST00000564243.1
 EIF3C



eukaryotic translation initiation factor 3, subunit C



chr5_+_154238042 0.099 ENST00000519211.1
ENST00000522458.1
ENST00000519903.1
ENST00000521450.1
ENST00000403027.2
 CNOT8




CCR4-NOT transcription complex, subunit 8




chr8_+_99129513 0.093 ENST00000522319.1
ENST00000401707.2
 POP1

processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae)

chr19_+_18669809 0.087 ENST00000602094.1
 KXD1
KxDL motif containing 1
chr19_-_51611623 0.083 ENST00000421832.2
 CTU1
cytosolic thiouridylase subunit 1
chr16_-_28415162 0.075 ENST00000398944.3
ENST00000398943.3
ENST00000380876.4
 EIF3CL


eukaryotic translation initiation factor 3, subunit C-like


chr16_+_28722809 0.074 ENST00000566866.1
 EIF3C
eukaryotic translation initiation factor 3, subunit C
chr7_-_12443501 0.068 ENST00000275358.3
 VWDE
von Willebrand factor D and EGF domains
chr11_-_63993690 0.068 ENST00000394546.2
ENST00000541278.1
 TRPT1

tRNA phosphotransferase 1

chr14_+_79745682 0.066 ENST00000557594.1
 NRXN3
neurexin 3
chr8_+_58907104 0.064 ENST00000361488.3
 FAM110B
family with sequence similarity 110, member B
chr21_-_26979786 0.063 ENST00000419219.1
ENST00000352957.4
ENST00000307301.7
 MRPL39


mitochondrial ribosomal protein L39


chr11_-_63993601 0.056 ENST00000545812.1
ENST00000394547.3
ENST00000317459.6
 TRPT1


tRNA phosphotransferase 1


chr6_-_159240415 0.052 ENST00000367075.3
 EZR
ezrin
chr19_+_50145328 0.041 ENST00000360565.3
 SCAF1
SR-related CTD-associated factor 1
chr17_-_3195876 0.039 ENST00000323404.1
 OR3A1
olfactory receptor, family 3, subfamily A, member 1
chr5_+_154238149 0.033 ENST00000519430.1
ENST00000520671.1
ENST00000521583.1
ENST00000518028.1
ENST00000519404.1
ENST00000519394.1
ENST00000518775.1
 CNOT8






CCR4-NOT transcription complex, subunit 8






chr17_+_54671047 0.029 ENST00000332822.4
 NOG
noggin
chr20_-_33735070 0.018 ENST00000374491.3
ENST00000542871.1
ENST00000374492.3
 EDEM2


ER degradation enhancer, mannosidase alpha-like 2


chr1_+_26869597 0.016 ENST00000530003.1
 RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr19_-_54567035 0.013 ENST00000366170.2
ENST00000425006.2
 VSTM1

V-set and transmembrane domain containing 1


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 6.4 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.3 0.8 GO:0019417 sulfur oxidation(GO:0019417)
0.3 1.5 GO:0090131 mesenchyme migration(GO:0090131)
0.2 5.0 GO:0016540 protein autoprocessing(GO:0016540)
0.2 2.0 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.2 0.7 GO:0035378 carbon dioxide transmembrane transport(GO:0035378)
0.2 1.3 GO:0022614 membrane to membrane docking(GO:0022614)
0.1 0.4 GO:0035674 tricarboxylic acid transmembrane transport(GO:0035674)
0.1 0.4 GO:0060721 spongiotrophoblast cell proliferation(GO:0060720) regulation of spongiotrophoblast cell proliferation(GO:0060721) cell proliferation involved in embryonic placenta development(GO:0060722) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.1 0.7 GO:0044034 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.1 0.6 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.1 0.2 GO:0031247 actin rod assembly(GO:0031247)
0.1 1.5 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.1 0.9 GO:0032074 negative regulation of nuclease activity(GO:0032074)
0.1 0.2 GO:0031938 regulation of chromatin silencing at telomere(GO:0031938)
0.1 1.1 GO:0023041 neuronal signal transduction(GO:0023041)
0.1 0.3 GO:0046462 monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.0 2.8 GO:0050919 negative chemotaxis(GO:0050919)
0.0 0.3 GO:0036337 Fas signaling pathway(GO:0036337)
0.0 0.1 GO:0042700 luteinizing hormone signaling pathway(GO:0042700)
0.0 1.1 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.2 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.0 0.3 GO:0036093 male germ cell proliferation(GO:0002176) germ cell proliferation(GO:0036093)
0.0 0.2 GO:0051138 positive regulation of NK T cell differentiation(GO:0051138)
0.0 0.7 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.0 0.9 GO:0097503 sialylation(GO:0097503)
0.0 0.6 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.5 GO:0034656 nucleobase-containing small molecule catabolic process(GO:0034656)
0.0 0.2 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.2 GO:1902416 positive regulation of mRNA binding(GO:1902416)
0.0 1.0 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.7 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.3 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
0.0 0.1 GO:0034227 tRNA thio-modification(GO:0034227)
0.0 0.7 GO:0061014 positive regulation of mRNA catabolic process(GO:0061014)
0.0 0.4 GO:0045116 protein neddylation(GO:0045116)
0.0 0.2 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.1 GO:0016078 tRNA catabolic process(GO:0016078)
0.0 0.4 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.2 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.0 0.5 GO:0034383 low-density lipoprotein particle clearance(GO:0034383)
0.0 0.1 GO:0010040 response to iron(II) ion(GO:0010040)
0.0 0.4 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.2 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.0 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.3 1.5 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.2 1.1 GO:0032449 CBM complex(GO:0032449)
0.1 0.7 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.1 0.7 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.1 0.2 GO:0031933 telomeric heterochromatin(GO:0031933)
0.1 0.3 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1 1.3 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 1.1 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.3 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 0.7 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.3 GO:0070652 HAUS complex(GO:0070652)
0.0 1.5 GO:0005871 kinesin complex(GO:0005871)
0.0 1.0 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 6.4 GO:0019898 extrinsic component of membrane(GO:0019898)
0.0 0.3 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.1 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.2 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 0.1 GO:0005683 U7 snRNP(GO:0005683)
0.0 0.3 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 0.4 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.3 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 6.4 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.4 1.1 GO:0038131 neuregulin receptor activity(GO:0038131)
0.2 1.0 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.2 0.7 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
0.2 0.5 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.1 0.7 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.1 2.1 GO:0004526 ribonuclease P activity(GO:0004526)
0.1 0.9 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 2.8 GO:0038191 neuropilin binding(GO:0038191)
0.1 0.6 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.1 0.9 GO:0004920 interleukin-10 receptor activity(GO:0004920)
0.1 0.5 GO:0004771 sterol esterase activity(GO:0004771)
0.1 0.4 GO:0015142 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.1 0.6 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.1 0.2 GO:0016749 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.1 0.3 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.0 1.5 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.2 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.4 GO:0070739 protein-glutamic acid ligase activity(GO:0070739)
0.0 0.9 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0 0.7 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.1 GO:0004963 follicle-stimulating hormone receptor activity(GO:0004963)
0.0 0.7 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.4 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.1 GO:0071209 U7 snRNA binding(GO:0071209)
0.0 0.4 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.8 GO:0071949 FAD binding(GO:0071949)
0.0 0.2 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 1.0 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.1 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.0 1.6 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.2 GO:0046790 virion binding(GO:0046790)
0.0 5.5 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.3 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.3 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 0.2 GO:0070628 proteasome binding(GO:0070628)
0.0 0.3 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.0 1.2 GO:0003725 double-stranded RNA binding(GO:0003725)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.9 PID_ALPHA_SYNUCLEIN_PATHWAY Alpha-synuclein signaling
0.0 1.3 PID_RHOA_PATHWAY RhoA signaling pathway
0.0 0.4 PID_ERB_GENOMIC_PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.4 PID_HIV_NEF_PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 2.8 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.3 SA_FAS_SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 2.3 PID_PDGFRB_PATHWAY PDGFR-beta signaling pathway
0.0 1.1 PID_P75_NTR_PATHWAY p75(NTR)-mediated signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 1.5 REACTOME_KINESINS Genes involved in Kinesins
0.0 0.9 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 1.3 REACTOME_RECYCLING_PATHWAY_OF_L1 Genes involved in Recycling pathway of L1
0.0 0.7 REACTOME_PHOSPHORYLATION_OF_CD3_AND_TCR_ZETA_CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 1.5 REACTOME_SMOOTH_MUSCLE_CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.6 REACTOME_CRMPS_IN_SEMA3A_SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.7 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.7 REACTOME_DEADENYLATION_OF_MRNA Genes involved in Deadenylation of mRNA
0.0 0.7 REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.2 REACTOME_TRAFFICKING_AND_PROCESSING_OF_ENDOSOMAL_TLR Genes involved in Trafficking and processing of endosomal TLR