Motif ID: ZIC3_ZIC4

Z-value: 0.428

Transcription factors associated with ZIC3_ZIC4:

Gene SymbolEntrez IDGene Name
ZIC3 ENSG00000156925.7 ZIC3
ZIC4 ENSG00000174963.13 ZIC4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
ZIC4hg19_v2_chr3_-_147124547_1471246470.537.8e-03Click!
ZIC3hg19_v2_chrX_+_136648297_1366483190.001.0e+00Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of ZIC3_ZIC4

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr8_+_1711918 0.903 ENST00000331222.4
CLN8
ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
chr5_-_180018540 0.730 ENST00000292641.3
SCGB3A1
secretoglobin, family 3A, member 1
chr13_+_35516390 0.724 ENST00000540320.1
ENST00000400445.3
ENST00000310336.4
NBEA


neurobeachin


chr5_+_76506706 0.684 ENST00000340978.3
ENST00000346042.3
ENST00000264917.5
ENST00000342343.4
ENST00000333194.4
PDE8B




phosphodiesterase 8B




chr4_-_149363662 0.626 ENST00000355292.3
ENST00000358102.3
NR3C2

nuclear receptor subfamily 3, group C, member 2

chr2_-_99552620 0.559 ENST00000428096.1
ENST00000397899.2
ENST00000420294.1
KIAA1211L


KIAA1211-like


chr2_+_8822113 0.558 ENST00000396290.1
ENST00000331129.3
ID2

inhibitor of DNA binding 2, dominant negative helix-loop-helix protein

chr17_-_74137374 0.525 ENST00000322957.6
FOXJ1
forkhead box J1
chr1_-_32801825 0.514 ENST00000329421.7
MARCKSL1
MARCKS-like 1
chr20_+_35201857 0.498 ENST00000373874.2
TGIF2
TGFB-induced factor homeobox 2
chr14_+_100848311 0.447 ENST00000542471.2
WDR25
WD repeat domain 25
chr9_-_124989804 0.443 ENST00000373755.2
ENST00000373754.2
LHX6

LIM homeobox 6

chr19_+_13135731 0.428 ENST00000587260.1
NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr11_+_73676281 0.410 ENST00000543947.1
DNAJB13
DnaJ (Hsp40) homolog, subfamily B, member 13
chr20_+_35201993 0.400 ENST00000373872.4
TGIF2
TGFB-induced factor homeobox 2
chr4_-_168155730 0.389 ENST00000502330.1
ENST00000357154.3
SPOCK3

sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3

chr11_+_2466218 0.386 ENST00000155840.5
KCNQ1
potassium voltage-gated channel, KQT-like subfamily, member 1
chr11_-_67272794 0.383 ENST00000436757.2
ENST00000356404.3
PITPNM1

phosphatidylinositol transfer protein, membrane-associated 1

chr17_+_39261584 0.372 ENST00000391415.1
KRTAP4-9
keratin associated protein 4-9
chr1_-_38273840 0.370 ENST00000373044.2
YRDC
yrdC N(6)-threonylcarbamoyltransferase domain containing
chr17_-_5026397 0.369 ENST00000250076.3
ZNF232
zinc finger protein 232
chr6_-_29595779 0.364 ENST00000355973.3
ENST00000377012.4
GABBR1

gamma-aminobutyric acid (GABA) B receptor, 1

chr4_+_81951957 0.362 ENST00000282701.2
BMP3
bone morphogenetic protein 3
chr11_+_73675873 0.353 ENST00000537753.1
ENST00000542350.1
DNAJB13

DnaJ (Hsp40) homolog, subfamily B, member 13

chr16_-_88717482 0.347 ENST00000261623.3
CYBA
cytochrome b-245, alpha polypeptide
chr17_+_78194205 0.332 ENST00000573809.1
ENST00000361193.3
ENST00000574967.1
ENST00000576126.1
ENST00000411502.3
ENST00000546047.2
SLC26A11





solute carrier family 26 (anion exchanger), member 11





chr4_-_168155700 0.328 ENST00000357545.4
ENST00000512648.1
SPOCK3

sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3

chr9_-_117880477 0.327 ENST00000534839.1
ENST00000340094.3
ENST00000535648.1
ENST00000346706.3
ENST00000345230.3
ENST00000350763.4
TNC





tenascin C





chr16_+_67465016 0.326 ENST00000326152.5
HSD11B2
hydroxysteroid (11-beta) dehydrogenase 2
chr2_+_219187871 0.324 ENST00000258362.3
PNKD
paroxysmal nonkinesigenic dyskinesia
chr17_+_56160768 0.320 ENST00000579991.2
DYNLL2
dynein, light chain, LC8-type 2
chr17_-_78194147 0.315 ENST00000534910.1
ENST00000326317.6
SGSH

N-sulfoglucosamine sulfohydrolase

chr12_-_51420108 0.297 ENST00000547198.1
SLC11A2
solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
chr13_+_25254693 0.292 ENST00000381946.3
ATP12A
ATPase, H+/K+ transporting, nongastric, alpha polypeptide
chr12_-_51419924 0.289 ENST00000541174.2
SLC11A2
solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
chr4_-_168155417 0.289 ENST00000511269.1
ENST00000506697.1
ENST00000512042.1
SPOCK3


sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3


chr13_+_25254545 0.288 ENST00000218548.6
ATP12A
ATPase, H+/K+ transporting, nongastric, alpha polypeptide
chr2_+_10183651 0.288 ENST00000305883.1
KLF11
Kruppel-like factor 11
chrX_-_34675391 0.287 ENST00000275954.3
TMEM47
transmembrane protein 47
chr6_+_33168637 0.284 ENST00000374677.3
SLC39A7
solute carrier family 39 (zinc transporter), member 7
chr10_+_50818343 0.281 ENST00000374115.3
SLC18A3
solute carrier family 18 (vesicular acetylcholine transporter), member 3
chr9_-_130742792 0.273 ENST00000373095.1
FAM102A
family with sequence similarity 102, member A
chr6_+_33168597 0.272 ENST00000374675.3
SLC39A7
solute carrier family 39 (zinc transporter), member 7
chr10_+_35416223 0.267 ENST00000489321.1
ENST00000427847.2
ENST00000345491.3
ENST00000395895.2
ENST00000374728.3
ENST00000487132.1
CREM





cAMP responsive element modulator





chr8_+_67976593 0.265 ENST00000262210.5
ENST00000412460.1
CSPP1

centrosome and spindle pole associated protein 1

chr12_+_108523133 0.263 ENST00000547525.1
WSCD2
WSC domain containing 2
chr12_+_56075330 0.260 ENST00000394252.3
METTL7B
methyltransferase like 7B
chr11_-_2182388 0.259 ENST00000397270.1
ENST00000421783.1
ENST00000397262.1
ENST00000250971.3
ENST00000381330.4
INS-IGF2
INS



INS-IGF2 readthrough
insulin



chr12_-_51420128 0.254 ENST00000262051.7
ENST00000547732.1
ENST00000262052.5
ENST00000546488.1
ENST00000550714.1
ENST00000548193.1
ENST00000547579.1
ENST00000546743.1
SLC11A2







solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2







chr4_-_168155300 0.253 ENST00000541637.1
SPOCK3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr17_+_260097 0.251 ENST00000360127.6
ENST00000571106.1
ENST00000491373.1
C17orf97


chromosome 17 open reading frame 97


chr12_+_51785057 0.243 ENST00000535225.2
SLC4A8
solute carrier family 4, sodium bicarbonate cotransporter, member 8
chr21_+_46117087 0.237 ENST00000400365.3
KRTAP10-12
keratin associated protein 10-12
chr12_+_108523489 0.235 ENST00000261400.3
WSCD2
WSC domain containing 2
chr7_-_135412925 0.230 ENST00000354042.4
SLC13A4
solute carrier family 13 (sodium/sulfate symporter), member 4
chr4_-_168155577 0.226 ENST00000541354.1
ENST00000509854.1
ENST00000512681.1
ENST00000421836.2
ENST00000510741.1
ENST00000510403.1
SPOCK3





sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3





chr1_+_3607228 0.225 ENST00000378285.1
ENST00000378280.1
ENST00000378288.4
TP73


tumor protein p73


chr1_+_85527987 0.222 ENST00000326813.8
ENST00000294664.6
ENST00000528899.1
WDR63


WD repeat domain 63


chr16_+_67596310 0.218 ENST00000264010.4
ENST00000401394.1
CTCF

CCCTC-binding factor (zinc finger protein)

chr6_+_143857949 0.217 ENST00000367584.4
PHACTR2
phosphatase and actin regulator 2
chr10_+_45455207 0.216 ENST00000334940.6
ENST00000374417.2
ENST00000340258.5
ENST00000427758.1
RASSF4



Ras association (RalGDS/AF-6) domain family member 4



chr19_-_40724246 0.214 ENST00000311308.6
TTC9B
tetratricopeptide repeat domain 9B
chr4_-_168155169 0.209 ENST00000534949.1
ENST00000535728.1
SPOCK3

sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3

chr19_+_13906250 0.208 ENST00000254323.2
ZSWIM4
zinc finger, SWIM-type containing 4
chr20_-_3154162 0.205 ENST00000360342.3
LZTS3
Homo sapiens leucine zipper, putative tumor suppressor family member 3 (LZTS3), mRNA.
chr14_-_21994525 0.205 ENST00000538754.1
SALL2
spalt-like transcription factor 2
chr9_-_140082983 0.201 ENST00000323927.2
ANAPC2
anaphase promoting complex subunit 2
chr10_+_14880287 0.200 ENST00000437161.2
HSPA14
heat shock 70kDa protein 14
chr14_+_31343747 0.200 ENST00000216361.4
ENST00000396618.3
ENST00000475087.1
COCH


cochlin


chr8_-_102217796 0.198 ENST00000519744.1
ENST00000311212.4
ENST00000521272.1
ENST00000519882.1
ZNF706



zinc finger protein 706



chr22_-_47134077 0.197 ENST00000541677.1
ENST00000216264.8
CERK

ceramide kinase

chrX_+_106871713 0.196 ENST00000372435.4
ENST00000372428.4
ENST00000372419.3
ENST00000543248.1
PRPS1



phosphoribosyl pyrophosphate synthetase 1



chr10_-_28287968 0.194 ENST00000305242.5
ARMC4
armadillo repeat containing 4
chr1_+_3569129 0.191 ENST00000354437.4
ENST00000357733.3
ENST00000346387.4
TP73


tumor protein p73


chr19_+_33685490 0.189 ENST00000253193.7
LRP3
low density lipoprotein receptor-related protein 3
chr10_-_13390270 0.189 ENST00000378614.4
ENST00000545675.1
ENST00000327347.5
SEPHS1


selenophosphate synthetase 1


chr17_-_15903002 0.187 ENST00000399277.1
ZSWIM7
zinc finger, SWIM-type containing 7
chr12_+_49932886 0.186 ENST00000257981.6
KCNH3
potassium voltage-gated channel, subfamily H (eag-related), member 3
chr5_-_76383133 0.185 ENST00000255198.2
ZBED3
zinc finger, BED-type containing 3
chr2_+_238768187 0.183 ENST00000254661.4
ENST00000409726.1
RAMP1

receptor (G protein-coupled) activity modifying protein 1

chr10_-_13390021 0.182 ENST00000537130.1
SEPHS1
selenophosphate synthetase 1
chr1_-_154928562 0.178 ENST00000368463.3
ENST00000539880.1
ENST00000542459.1
ENST00000368460.3
ENST00000368465.1
PBXIP1




pre-B-cell leukemia homeobox interacting protein 1




chr10_+_28966271 0.175 ENST00000375533.3
BAMBI
BMP and activin membrane-bound inhibitor
chr6_+_3849584 0.170 ENST00000380274.1
ENST00000380272.3
FAM50B

family with sequence similarity 50, member B

chr20_-_18038521 0.166 ENST00000278780.6
OVOL2
ovo-like zinc finger 2
chr5_+_137688285 0.166 ENST00000314358.5
KDM3B
lysine (K)-specific demethylase 3B
chr19_+_13135790 0.164 ENST00000358552.3
NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr2_-_42721110 0.164 ENST00000394973.4
ENST00000306078.1
KCNG3

potassium voltage-gated channel, subfamily G, member 3

chr9_+_116638562 0.163 ENST00000374126.5
ENST00000288466.7
ZNF618

zinc finger protein 618

chr7_+_150758304 0.162 ENST00000482950.1
ENST00000463414.1
ENST00000310317.5
SLC4A2


solute carrier family 4 (anion exchanger), member 2


chr13_+_39261224 0.162 ENST00000280481.7
FREM2
FRAS1 related extracellular matrix protein 2
chr11_-_119211525 0.161 ENST00000528368.1
C1QTNF5
C1q and tumor necrosis factor related protein 5
chr4_+_52917451 0.154 ENST00000295213.4
ENST00000419395.2
SPATA18

spermatogenesis associated 18

chr16_+_4897912 0.154 ENST00000545171.1
UBN1
ubinuclein 1
chr13_+_27131798 0.153 ENST00000361042.4
WASF3
WAS protein family, member 3
chr17_+_38219063 0.152 ENST00000584985.1
ENST00000264637.4
ENST00000450525.2
THRA


thyroid hormone receptor, alpha


chr12_-_48398104 0.151 ENST00000337299.6
ENST00000380518.3
COL2A1

collagen, type II, alpha 1

chr9_-_98279241 0.149 ENST00000437951.1
ENST00000375274.2
ENST00000430669.2
ENST00000468211.2
PTCH1



patched 1



chr4_+_74718906 0.147 ENST00000226524.3
PF4V1
platelet factor 4 variant 1
chr10_+_98592674 0.147 ENST00000356016.3
ENST00000371097.4
LCOR

ligand dependent nuclear receptor corepressor

chr11_-_67275542 0.142 ENST00000531506.1
CDK2AP2
cyclin-dependent kinase 2 associated protein 2
chr11_-_73694346 0.140 ENST00000310473.3
UCP2
uncoupling protein 2 (mitochondrial, proton carrier)
chr16_+_58059470 0.139 ENST00000219271.3
MMP15
matrix metallopeptidase 15 (membrane-inserted)
chr12_-_59314246 0.137 ENST00000320743.3
LRIG3
leucine-rich repeats and immunoglobulin-like domains 3
chr8_-_27462822 0.136 ENST00000522098.1
CLU
clusterin
chr17_-_80291818 0.133 ENST00000269389.3
ENST00000581691.1
SECTM1

secreted and transmembrane 1

chr16_+_28996364 0.133 ENST00000564277.1
LAT
linker for activation of T cells
chr7_+_149571045 0.132 ENST00000479613.1
ENST00000606024.1
ENST00000464662.1
ENST00000425642.2
ATP6V0E2



ATPase, H+ transporting V0 subunit e2



chr9_+_214842 0.131 ENST00000453981.1
ENST00000432829.2
DOCK8

dedicator of cytokinesis 8

chr1_+_38273988 0.130 ENST00000446260.2
C1orf122
chromosome 1 open reading frame 122
chr2_+_11273179 0.130 ENST00000381585.3
ENST00000405022.3
C2orf50

chromosome 2 open reading frame 50

chr20_+_30458431 0.128 ENST00000375938.4
ENST00000535842.1
ENST00000310998.4
ENST00000375921.2
TTLL9



tubulin tyrosine ligase-like family, member 9



chr17_-_79623597 0.128 ENST00000574024.1
ENST00000331056.5
PDE6G

phosphodiesterase 6G, cGMP-specific, rod, gamma

chr5_-_179499108 0.128 ENST00000521389.1
RNF130
ring finger protein 130
chr1_+_3569072 0.128 ENST00000378295.4
ENST00000604074.1
TP73

tumor protein p73

chr18_+_11752040 0.127 ENST00000423027.3
GNAL
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
chr17_+_79761997 0.127 ENST00000400723.3
ENST00000570996.1
GCGR

glucagon receptor

chr9_-_85678043 0.126 ENST00000376447.3
ENST00000340717.4
RASEF

RAS and EF-hand domain containing

chr10_+_134145735 0.125 ENST00000368613.4
LRRC27
leucine rich repeat containing 27
chr16_+_4364762 0.124 ENST00000262366.3
GLIS2
GLIS family zinc finger 2
chr17_-_50236039 0.124 ENST00000451037.2
CA10
carbonic anhydrase X
chr19_-_291365 0.122 ENST00000591572.1
ENST00000269812.3
ENST00000434325.2
PPAP2C


phosphatidic acid phosphatase type 2C


chr13_+_27131887 0.122 ENST00000335327.5
WASF3
WAS protein family, member 3
chr19_+_45251804 0.121 ENST00000164227.5
BCL3
B-cell CLL/lymphoma 3
chr22_+_22735135 0.121 ENST00000390297.2
IGLV1-44
immunoglobulin lambda variable 1-44
chr5_-_179499086 0.120 ENST00000261947.4
RNF130
ring finger protein 130
chr6_-_39082922 0.118 ENST00000229903.4
SAYSD1
SAYSVFN motif domain containing 1
chr19_+_49122548 0.118 ENST00000245222.4
ENST00000340932.3
ENST00000601712.1
ENST00000600537.1
SPHK2



sphingosine kinase 2



chr16_-_69364467 0.117 ENST00000288022.1
PDF
peptide deformylase (mitochondrial)
chr12_-_57400227 0.116 ENST00000300101.2
ZBTB39
zinc finger and BTB domain containing 39
chr20_-_4982132 0.115 ENST00000338244.1
ENST00000424750.2
SLC23A2

solute carrier family 23 (ascorbic acid transporter), member 2

chr19_+_19174795 0.115 ENST00000318596.7
SLC25A42
solute carrier family 25, member 42
chr9_-_74383799 0.114 ENST00000377044.4
TMEM2
transmembrane protein 2
chr10_-_100027943 0.113 ENST00000260702.3
LOXL4
lysyl oxidase-like 4
chr12_+_58176525 0.112 ENST00000543727.1
ENST00000540550.1
ENST00000323833.8
ENST00000350762.5
ENST00000550559.1
ENST00000548851.1
ENST00000434359.1
ENST00000457189.1
TSFM







Ts translation elongation factor, mitochondrial







chr10_+_49514698 0.112 ENST00000432379.1
ENST00000429041.1
ENST00000374189.1
MAPK8


mitogen-activated protein kinase 8


chr19_+_49122785 0.111 ENST00000598088.1
SPHK2
sphingosine kinase 2
chr1_-_21503337 0.110 ENST00000400422.1
ENST00000602326.1
ENST00000411888.1
ENST00000438975.1
EIF4G3



eukaryotic translation initiation factor 4 gamma, 3



chr17_-_73178599 0.109 ENST00000578238.1
SUMO2
small ubiquitin-like modifier 2
chr11_-_74109422 0.109 ENST00000298198.4
PGM2L1
phosphoglucomutase 2-like 1
chr11_-_118023490 0.108 ENST00000324727.4
SCN4B
sodium channel, voltage-gated, type IV, beta subunit
chr18_+_11751493 0.108 ENST00000269162.5
GNAL
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
chr4_-_492891 0.108 ENST00000338977.5
ENST00000511833.2
ZNF721

zinc finger protein 721

chr16_+_67840986 0.107 ENST00000561639.1
ENST00000567852.1
ENST00000565148.1
ENST00000388833.3
ENST00000561654.1
ENST00000431934.2
TSNAXIP1





translin-associated factor X interacting protein 1





chr6_+_134274322 0.106 ENST00000367871.1
ENST00000237264.4
TBPL1

TBP-like 1

chr2_-_56150184 0.106 ENST00000394554.1
EFEMP1
EGF containing fibulin-like extracellular matrix protein 1
chr11_+_73019282 0.106 ENST00000263674.3
ARHGEF17
Rho guanine nucleotide exchange factor (GEF) 17
chr15_+_65822756 0.106 ENST00000562901.1
ENST00000261875.5
ENST00000442729.2
ENST00000565299.1
ENST00000568793.1
PTPLAD1




protein tyrosine phosphatase-like A domain containing 1




chr17_-_50235423 0.104 ENST00000340813.6
CA10
carbonic anhydrase X
chr2_-_98280383 0.104 ENST00000289228.5
ACTR1B
ARP1 actin-related protein 1 homolog B, centractin beta (yeast)
chr10_+_21823079 0.102 ENST00000377100.3
ENST00000377072.3
ENST00000446906.2
MLLT10


myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10


chr15_+_65823092 0.102 ENST00000566074.1
PTPLAD1
protein tyrosine phosphatase-like A domain containing 1
chr11_-_57004658 0.102 ENST00000606794.1
APLNR
apelin receptor
chr3_-_132441209 0.100 ENST00000383282.2
ENST00000326682.8
ENST00000343113.4
ENST00000337331.5
NPHP3



nephronophthisis 3 (adolescent)



chr7_+_302918 0.100 ENST00000599994.1
AC187652.1
Protein LOC100996433
chr20_+_60698180 0.100 ENST00000361670.3
LSM14B
LSM14B, SCD6 homolog B (S. cerevisiae)
chr1_-_6052463 0.099 ENST00000378156.4
NPHP4
nephronophthisis 4
chr1_+_38273818 0.099 ENST00000373042.4
C1orf122
chromosome 1 open reading frame 122
chr16_+_67840668 0.099 ENST00000415766.3
TSNAXIP1
translin-associated factor X interacting protein 1
chr17_-_4871085 0.099 ENST00000575142.1
ENST00000206020.3
SPAG7

sperm associated antigen 7

chr11_-_76091986 0.099 ENST00000260045.3
PRKRIR
protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor)
chr22_+_29702572 0.099 ENST00000407647.2
ENST00000416823.1
ENST00000428622.1
GAS2L1


growth arrest-specific 2 like 1


chr19_-_14316980 0.099 ENST00000361434.3
ENST00000340736.6
LPHN1

latrophilin 1

chr9_+_4490394 0.099 ENST00000262352.3
SLC1A1
solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
chr3_+_184097836 0.099 ENST00000204604.1
ENST00000310236.3
CHRD

chordin

chr11_-_65150103 0.098 ENST00000294187.6
ENST00000398802.1
ENST00000360662.3
ENST00000377152.2
ENST00000530936.1
SLC25A45




solute carrier family 25, member 45




chr7_-_105925558 0.098 ENST00000222553.3
NAMPT
nicotinamide phosphoribosyltransferase
chr14_+_91580708 0.097 ENST00000518868.1
C14orf159
chromosome 14 open reading frame 159
chr6_+_170615819 0.097 ENST00000476287.1
ENST00000252510.9
FAM120B

family with sequence similarity 120B

chr1_-_205782304 0.096 ENST00000367137.3
SLC41A1
solute carrier family 41 (magnesium transporter), member 1
chr1_+_52521797 0.096 ENST00000313334.8
BTF3L4
basic transcription factor 3-like 4
chr2_+_20646824 0.096 ENST00000272233.4
RHOB
ras homolog family member B
chr14_+_54976546 0.096 ENST00000216420.7
CGRRF1
cell growth regulator with ring finger domain 1
chr7_-_100808843 0.095 ENST00000249330.2
VGF
VGF nerve growth factor inducible
chrX_+_24711997 0.095 ENST00000379068.3
ENST00000379059.3
POLA1

polymerase (DNA directed), alpha 1, catalytic subunit

chr21_+_46020497 0.095 ENST00000380102.2
KRTAP10-7
keratin associated protein 10-7
chr14_+_91580777 0.094 ENST00000525393.2
ENST00000428926.2
ENST00000517362.1
C14orf159


chromosome 14 open reading frame 159


chr1_+_114471809 0.093 ENST00000426820.2
HIPK1
homeodomain interacting protein kinase 1
chr10_+_127408263 0.093 ENST00000337623.3
C10orf137
erythroid differentiation regulatory factor 1
chr10_+_70939983 0.092 ENST00000359655.4
ENST00000422378.1
SUPV3L1

suppressor of var1, 3-like 1 (S. cerevisiae)

chr4_+_492985 0.092 ENST00000296306.7
ENST00000536264.1
ENST00000310340.5
ENST00000453061.2
ENST00000504346.1
ENST00000503111.1
ENST00000383028.4
ENST00000509768.1
PIGG







phosphatidylinositol glycan anchor biosynthesis, class G







chr5_+_121647764 0.092 ENST00000261368.8
ENST00000379533.2
ENST00000379536.2
ENST00000379538.3
SNCAIP



synuclein, alpha interacting protein



chr3_-_112356944 0.091 ENST00000461431.1
CCDC80
coiled-coil domain containing 80
chr19_-_18385246 0.090 ENST00000608950.1
ENST00000600328.3
ENST00000600359.3
ENST00000392413.4
KIAA1683



KIAA1683



chr7_-_100808394 0.090 ENST00000445482.2
VGF
VGF nerve growth factor inducible
chr16_+_89753070 0.089 ENST00000353379.7
ENST00000505473.1
ENST00000564192.1
CDK10


cyclin-dependent kinase 10


chr19_-_12992244 0.088 ENST00000538460.1
DNASE2
deoxyribonuclease II, lysosomal
chr17_-_15902951 0.088 ENST00000472495.1
ZSWIM7
zinc finger, SWIM-type containing 7
chr16_+_30205754 0.087 ENST00000354723.6
ENST00000355544.5
SULT1A3

sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3

chr5_+_121647877 0.087 ENST00000514497.2
ENST00000261367.7
SNCAIP

synuclein, alpha interacting protein

chr17_-_27893990 0.086 ENST00000307201.4
ABHD15
abhydrolase domain containing 15
chr17_-_4463856 0.086 ENST00000574584.1
ENST00000381550.3
ENST00000301395.3
GGT6


gamma-glutamyltransferase 6


chr7_+_99775520 0.085 ENST00000317296.5
ENST00000422690.1
ENST00000439782.1
STAG3


stromal antigen 3


chr3_-_134093395 0.083 ENST00000249883.5
AMOTL2
angiomotin like 2
chr1_+_218519577 0.083 ENST00000366930.4
ENST00000366929.4
TGFB2

transforming growth factor, beta 2

chr7_+_99775366 0.082 ENST00000394018.2
ENST00000416412.1
STAG3

stromal antigen 3

chr14_+_78266436 0.081 ENST00000557501.1
ENST00000341211.5
ADCK1

aarF domain containing kinase 1

chr12_+_31812121 0.080 ENST00000395763.3
METTL20
methyltransferase like 20
chr19_+_46806856 0.080 ENST00000300862.3
HIF3A
hypoxia inducible factor 3, alpha subunit
chrX_-_78622805 0.080 ENST00000373298.2
ITM2A
integral membrane protein 2A

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0002514 B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663)
0.2 0.8 GO:0015692 lead ion transport(GO:0015692)
0.2 0.8 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.1 0.6 GO:0061030 epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.1 0.4 GO:0016260 selenocysteine biosynthetic process(GO:0016260)
0.1 0.4 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.1 0.3 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.1 0.3 GO:0033861 negative regulation of NAD(P)H oxidase activity(GO:0033861)
0.1 0.2 GO:0006669 sphinganine-1-phosphate biosynthetic process(GO:0006669)
0.1 0.2 GO:0021919 BMP signaling pathway involved in spinal cord dorsal/ventral patterning(GO:0021919)
0.1 0.3 GO:1904844 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.1 1.6 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1 0.3 GO:0060447 bud outgrowth involved in lung branching(GO:0060447)
0.1 0.3 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.1 0.2 GO:0008050 female courtship behavior(GO:0008050) positive regulation of female receptivity(GO:0045925)
0.0 0.2 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
0.0 0.0 GO:0072038 mesenchymal stem cell maintenance involved in nephron morphogenesis(GO:0072038)
0.0 0.1 GO:0003274 endocardial cushion fusion(GO:0003274)
0.0 0.1 GO:0017186 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186)
0.0 0.9 GO:0038092 nodal signaling pathway(GO:0038092)
0.0 0.1 GO:0045082 positive regulation of interleukin-10 biosynthetic process(GO:0045082)
0.0 0.3 GO:0015870 acetylcholine transport(GO:0015870)
0.0 0.2 GO:0046101 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.0 0.1 GO:0043686 co-translational protein modification(GO:0043686)
0.0 0.1 GO:0015993 L-ascorbic acid transport(GO:0015882) molecular hydrogen transport(GO:0015993) transepithelial L-ascorbic acid transport(GO:0070904)
0.0 0.1 GO:0071106 coenzyme A transport(GO:0015880) coenzyme A transmembrane transport(GO:0035349) adenosine 3',5'-bisphosphate transmembrane transport(GO:0071106) AMP transport(GO:0080121)
0.0 0.1 GO:1902595 regulation of DNA replication origin binding(GO:1902595)
0.0 0.1 GO:0010157 response to chlorate(GO:0010157)
0.0 0.2 GO:0010216 maintenance of DNA methylation(GO:0010216) regulation of centromeric sister chromatid cohesion(GO:0070602)
0.0 0.1 GO:0032474 otolith morphogenesis(GO:0032474)
0.0 0.1 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.0 0.0 GO:1902512 positive regulation of apoptotic DNA fragmentation(GO:1902512)
0.0 0.6 GO:0008272 sulfate transport(GO:0008272)
0.0 0.4 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0 0.7 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.0 0.4 GO:0060453 regulation of gastric acid secretion(GO:0060453)
0.0 0.1 GO:0071344 diphosphate metabolic process(GO:0071344)
0.0 0.3 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.1 GO:0060214 endocardium formation(GO:0060214)
0.0 0.5 GO:0060044 negative regulation of cardiac muscle cell proliferation(GO:0060044)
0.0 0.1 GO:0060994 regulation of transcription from RNA polymerase II promoter involved in kidney development(GO:0060994)
0.0 0.6 GO:0010248 establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
0.0 0.1 GO:0006272 leading strand elongation(GO:0006272)
0.0 0.1 GO:0045924 regulation of female receptivity(GO:0045924)
0.0 0.1 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
0.0 0.2 GO:2000035 regulation of stem cell division(GO:2000035)
0.0 0.1 GO:0000957 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.0 0.1 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.1 GO:1902998 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.0 0.2 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 0.3 GO:0003084 positive regulation of systemic arterial blood pressure(GO:0003084)
0.0 0.2 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.0 0.2 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.0 0.1 GO:0048496 maintenance of organ identity(GO:0048496)
0.0 0.1 GO:0051066 dihydrobiopterin metabolic process(GO:0051066)
0.0 0.0 GO:0038109 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109)
0.0 0.2 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 0.0 GO:0060434 bronchus morphogenesis(GO:0060434)
0.0 0.1 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.0 0.1 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
0.0 0.1 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.0 0.1 GO:0071557 negative regulation of chromatin silencing at rDNA(GO:0061188) histone H3-K27 demethylation(GO:0071557)
0.0 0.1 GO:0009212 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
0.0 0.2 GO:0072718 response to cisplatin(GO:0072718)
0.0 0.1 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.0 0.0 GO:0060931 sinoatrial node cell development(GO:0060931)
0.0 0.1 GO:0002317 plasma cell differentiation(GO:0002317)
0.0 0.1 GO:0060235 lens induction in camera-type eye(GO:0060235)
0.0 0.1 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.0 0.6 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.1 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.0 0.8 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.0 0.1 GO:0061743 motor learning(GO:0061743)
0.0 0.1 GO:0000066 mitochondrial ornithine transport(GO:0000066)
0.0 0.1 GO:0009447 putrescine catabolic process(GO:0009447)
0.0 0.2 GO:0060174 limb bud formation(GO:0060174)
0.0 0.0 GO:0021718 superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.0 0.2 GO:0003356 regulation of cilium beat frequency(GO:0003356)
0.0 0.1 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.0 0.2 GO:0035413 positive regulation of catenin import into nucleus(GO:0035413)
0.0 0.0 GO:0010847 regulation of chromatin assembly(GO:0010847) negative regulation of protein import into nucleus, translocation(GO:0033159) protein auto-ADP-ribosylation(GO:0070213)
0.0 0.3 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.0 0.1 GO:0061055 myotome development(GO:0061055)
0.0 0.1 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.0 GO:0072299 adrenal cortex development(GO:0035801) adrenal cortex formation(GO:0035802) negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302)
0.0 0.9 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 0.1 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.0 0.1 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.1 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.0 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0070826 paraferritin complex(GO:0070826)
0.1 0.6 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.1 0.3 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.1 0.3 GO:0097196 Shu complex(GO:0097196)
0.1 0.3 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0 0.2 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.0 0.1 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.0 0.2 GO:1903440 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.0 0.3 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.1 GO:0044294 dendritic growth cone(GO:0044294)
0.0 0.3 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.4 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.2 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.1 GO:0044301 climbing fiber(GO:0044301)
0.0 0.1 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.3 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.1 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.1 GO:0030893 meiotic cohesin complex(GO:0030893)
0.0 0.2 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 1.1 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.1 0.6 GO:0008900 hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.1 0.4 GO:0016781 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.1 0.3 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.1 0.3 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.1 0.3 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.1 0.3 GO:1901375 acetylcholine transmembrane transporter activity(GO:0005277) acetate ester transmembrane transporter activity(GO:1901375)
0.1 0.4 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.1 0.4 GO:0001727 lipid kinase activity(GO:0001727)
0.1 1.7 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.3 GO:0047820 D-glutamate cyclase activity(GO:0047820)
0.1 0.5 GO:0045545 syndecan binding(GO:0045545)
0.0 0.1 GO:0004531 deoxyribonuclease II activity(GO:0004531)
0.0 0.2 GO:0004948 calcitonin receptor activity(GO:0004948) calcitonin receptor binding(GO:0031716)
0.0 0.4 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.1 GO:0004967 glucagon receptor activity(GO:0004967)
0.0 0.5 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.1 GO:0016603 glutaminyl-peptide cyclotransferase activity(GO:0016603)
0.0 0.6 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0 0.1 GO:0070890 L-ascorbate:sodium symporter activity(GO:0008520) sodium-dependent multivitamin transmembrane transporter activity(GO:0008523) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.0 0.1 GO:0015228 coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
0.0 0.1 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.0 0.2 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.1 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.0 0.2 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.4 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.1 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0 0.1 GO:0031751 D4 dopamine receptor binding(GO:0031751)
0.0 0.3 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.0 0.1 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 0.1 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 0.2 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 0.1 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.0 0.4 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.3 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.1 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.0 0.1 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 0.7 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.6 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.3 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.1 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.1 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 0.2 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.5 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.2 GO:0031386 protein tag(GO:0031386)
0.0 0.1 GO:0047685 amine sulfotransferase activity(GO:0047685)
0.0 0.1 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 0.1 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.1 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.4 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 0.1 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.1 GO:0015254 glycerol channel activity(GO:0015254)
0.0 0.0 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.0 0.0 GO:0038181 bile acid receptor activity(GO:0038181)
0.0 0.1 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.0 0.1 GO:0070404 NADH binding(GO:0070404)
0.0 0.1 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0 0.2 GO:0005113 patched binding(GO:0005113)
0.0 0.1 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 PID_NFKAPPAB_ATYPICAL_PATHWAY Atypical NF-kappaB pathway
0.0 1.6 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.9 PID_HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.3 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.0 0.8 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.2 REACTOME_ADENYLATE_CYCLASE_ACTIVATING_PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.4 REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.3 REACTOME_SIGNAL_ATTENUATION Genes involved in Signal attenuation
0.0 0.3 REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.3 REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.2 REACTOME_COMMON_PATHWAY Genes involved in Common Pathway
0.0 0.6 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases