Motif ID: ZKSCAN3

Z-value: 0.324


Transcription factors associated with ZKSCAN3:

Gene SymbolEntrez IDGene Name
ZKSCAN3 ENSG00000189298.9 ZKSCAN3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
ZKSCAN3hg19_v2_chr6_+_28317685_283177610.311.4e-01Click!


Activity profile for motif ZKSCAN3.

activity profile for motif ZKSCAN3


Sorted Z-values histogram for motif ZKSCAN3

Sorted Z-values for motif ZKSCAN3



Network of associatons between targets according to the STRING database.



First level regulatory network of ZKSCAN3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_3598871 1.029 ENST00000603362.1
ENST00000604479.1
 TP73

tumor protein p73

chr15_-_41624685 0.864 ENST00000560640.1
ENST00000220514.3
 OIP5

Opa interacting protein 5

chr15_+_41624892 0.762 ENST00000260359.6
ENST00000450318.1
ENST00000450592.2
ENST00000559596.1
ENST00000414849.2
ENST00000560747.1
ENST00000560177.1
 NUSAP1






nucleolar and spindle associated protein 1






chr9_+_124926856 0.553 ENST00000418632.1
 MORN5
MORN repeat containing 5
chr19_+_39786962 0.469 ENST00000333625.2
 IFNL1
interferon, lambda 1
chr18_-_74728998 0.333 ENST00000359645.3
ENST00000397875.3
ENST00000397869.3
ENST00000578193.1
ENST00000578873.1
ENST00000397866.4
ENST00000528160.1
ENST00000527041.1
ENST00000526111.1
ENST00000397865.5
ENST00000382582.3
 MBP










myelin basic protein










chr19_+_39759154 0.320 ENST00000331982.5
 IFNL2
interferon, lambda 2
chr16_+_2479390 0.284 ENST00000397066.4
 CCNF
cyclin F
chr19_-_39735646 0.259 ENST00000413851.2
 IFNL3
interferon, lambda 3
chr10_+_6779326 0.229 ENST00000417112.1
 RP11-554I8.2
RP11-554I8.2
chr9_+_138235095 0.224 ENST00000320778.2
 C9orf62
chromosome 9 open reading frame 62
chr2_+_191745560 0.213 ENST00000338435.4
 GLS
glutaminase
chr5_+_65018017 0.197 ENST00000380985.5
ENST00000502464.1
 NLN

neurolysin (metallopeptidase M3 family)

chr14_-_106069247 0.174 ENST00000479229.1
 RP11-731F5.1
RP11-731F5.1
chr14_-_80697396 0.138 ENST00000557010.1
 DIO2
deiodinase, iodothyronine, type II
chr7_+_155089486 0.133 ENST00000340368.4
ENST00000344756.4
ENST00000425172.1
ENST00000342407.5
 INSIG1



insulin induced gene 1



chr10_+_21823079 0.127 ENST00000377100.3
ENST00000377072.3
ENST00000446906.2
 MLLT10


myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10


chrX_+_153775821 0.125 ENST00000263518.6
ENST00000470142.1
ENST00000393549.2
ENST00000455588.2
ENST00000369602.3
 IKBKG




inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma




chr12_-_3982511 0.124 ENST00000427057.2
ENST00000228820.4
 PARP11

poly (ADP-ribose) polymerase family, member 11

chr12_-_3982548 0.117 ENST00000397096.2
ENST00000447133.3
ENST00000450737.2
 PARP11


poly (ADP-ribose) polymerase family, member 11


chr22_-_50312052 0.113 ENST00000330817.6
 ALG12
ALG12, alpha-1,6-mannosyltransferase
chr11_-_64013288 0.111 ENST00000542235.1
 PPP1R14B
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr14_-_106926724 0.106 ENST00000434710.1
 IGHV3-43
immunoglobulin heavy variable 3-43
chr22_+_50312316 0.105 ENST00000328268.4
 CRELD2
cysteine-rich with EGF-like domains 2
chr19_-_42348692 0.099 ENST00000330743.3
ENST00000601246.1
 LYPD4

LY6/PLAUR domain containing 4

chr5_-_65017921 0.097 ENST00000381007.4
 SGTB
small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta
chr15_+_74610894 0.097 ENST00000558821.1
ENST00000268082.4
 CCDC33

coiled-coil domain containing 33

chr7_+_155090271 0.096 ENST00000476756.1
 INSIG1
insulin induced gene 1
chr8_+_123793633 0.092 ENST00000314393.4
 ZHX2
zinc fingers and homeoboxes 2
chr10_+_21823243 0.092 ENST00000307729.7
ENST00000377091.2
 MLLT10

myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10

chr19_-_49258606 0.091 ENST00000310160.3
 FUT1
fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
chr11_-_64013663 0.083 ENST00000392210.2
 PPP1R14B
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr22_+_50312274 0.078 ENST00000404488.3
 CRELD2
cysteine-rich with EGF-like domains 2
chr22_+_50312379 0.078 ENST00000407217.3
ENST00000403427.3
 CRELD2

cysteine-rich with EGF-like domains 2

chr6_-_31508304 0.077 ENST00000376177.2
 DDX39B
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B
chr1_-_28415075 0.074 ENST00000373863.3
ENST00000436342.2
ENST00000540618.1
ENST00000545175.1
 EYA3



eyes absent homolog 3 (Drosophila)



chr7_-_155089251 0.064 ENST00000609974.1
 AC144652.1
AC144652.1
chrX_-_153775426 0.059 ENST00000393562.2
 G6PD
glucose-6-phosphate dehydrogenase
chr1_+_93913713 0.051 ENST00000604705.1
ENST00000370253.2
 FNBP1L

formin binding protein 1-like

chr12_+_109535373 0.050 ENST00000242576.2
 UNG
uracil-DNA glycosylase
chr14_+_94492674 0.041 ENST00000203664.5
ENST00000553723.1
 OTUB2

OTU domain, ubiquitin aldehyde binding 2

chrX_-_135338503 0.041 ENST00000370663.5
 MAP7D3
MAP7 domain containing 3
chr12_+_100867694 0.041 ENST00000392986.3
ENST00000549996.1
 NR1H4

nuclear receptor subfamily 1, group H, member 4

chr1_-_115259337 0.033 ENST00000369535.4
 NRAS
neuroblastoma RAS viral (v-ras) oncogene homolog
chr1_+_93913665 0.029 ENST00000271234.7
ENST00000370256.4
ENST00000260506.8
 FNBP1L


formin binding protein 1-like


chr1_-_19811996 0.028 ENST00000264203.3
ENST00000401084.2
 CAPZB

capping protein (actin filament) muscle Z-line, beta

chr3_-_122512619 0.023 ENST00000383659.1
ENST00000306103.2
 HSPBAP1

HSPB (heat shock 27kDa) associated protein 1

chr19_+_32836499 0.022 ENST00000311921.4
ENST00000544431.1
ENST00000355898.5
 ZNF507


zinc finger protein 507


chr5_+_140079919 0.020 ENST00000274712.3
 ZMAT2
zinc finger, matrin-type 2
chrX_+_150863596 0.019 ENST00000448726.1
ENST00000538575.1
 PRRG3

proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane)

chr1_-_28415204 0.019 ENST00000373871.3
 EYA3
eyes absent homolog 3 (Drosophila)
chr16_-_28506840 0.017 ENST00000569430.1
 CLN3
ceroid-lipofuscinosis, neuronal 3
chr1_-_19811962 0.013 ENST00000375142.1
ENST00000264202.6
 CAPZB

capping protein (actin filament) muscle Z-line, beta

chr16_-_745946 0.007 ENST00000562563.1
 FBXL16
F-box and leucine-rich repeat protein 16
chr1_+_226250379 0.007 ENST00000366815.3
ENST00000366814.3
 H3F3A

H3 histone, family 3A

chr12_+_109535923 0.005 ENST00000336865.2
 UNG
uracil-DNA glycosylase
chr5_-_114598548 0.002 ENST00000379615.3
ENST00000419445.1
 PGGT1B

protein geranylgeranyltransferase type I, beta subunit


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.1 0.5 GO:0032696 negative regulation of interleukin-13 production(GO:0032696)
0.1 0.3 GO:1904209 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.0 0.2 GO:1902809 regulation of skeletal muscle fiber differentiation(GO:1902809)
0.0 1.0 GO:0060044 negative regulation of cardiac muscle cell proliferation(GO:0060044)
0.0 0.8 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.1 GO:0006543 glutamine catabolic process(GO:0006543)
0.0 0.9 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.1 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.0 0.3 GO:0010826 negative regulation of centrosome duplication(GO:0010826)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0032002 interleukin-28 receptor complex(GO:0032002)
0.1 0.2 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.3 GO:0033269 internode region of axon(GO:0033269)
0.0 0.9 GO:0010369 chromocenter(GO:0010369)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.1 GO:0004359 glutaminase activity(GO:0004359)
0.0 0.1 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.3 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere