Motif ID: ZNF35

Z-value: 0.296


Transcription factors associated with ZNF35:

Gene SymbolEntrez IDGene Name
ZNF35 ENSG00000169981.6 ZNF35

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
ZNF35hg19_v2_chr3_+_44690211_446902670.386.8e-02Click!


Activity profile for motif ZNF35.

activity profile for motif ZNF35


Sorted Z-values histogram for motif ZNF35

Sorted Z-values for motif ZNF35



Network of associatons between targets according to the STRING database.



First level regulatory network of ZNF35

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr13_-_36429763 1.019 ENST00000379893.1
 DCLK1
doublecortin-like kinase 1
chr3_-_148939835 0.743 ENST00000264613.6
 CP
ceruloplasmin (ferroxidase)
chr6_+_32812568 0.704 ENST00000414474.1
 PSMB9
proteasome (prosome, macropain) subunit, beta type, 9
chr14_+_76776957 0.519 ENST00000512784.1
 ESRRB
estrogen-related receptor beta
chrX_+_9431324 0.460 ENST00000407597.2
ENST00000424279.1
ENST00000536365.1
ENST00000441088.1
ENST00000380961.1
ENST00000415293.1
 TBL1X





transducin (beta)-like 1X-linked





chr17_-_63557759 0.336 ENST00000307078.5
 AXIN2
axin 2
chr1_+_61869748 0.259 ENST00000357977.5
 NFIA
nuclear factor I/A
chr14_-_31889782 0.250 ENST00000543095.2
 HEATR5A
HEAT repeat containing 5A
chr7_+_80231466 0.236 ENST00000309881.7
ENST00000534394.1
 CD36

CD36 molecule (thrombospondin receptor)

chr18_+_74240610 0.202 ENST00000578092.1
ENST00000578613.1
ENST00000583578.1
 LINC00908


long intergenic non-protein coding RNA 908


chr12_+_51318513 0.188 ENST00000332160.4
 METTL7A
methyltransferase like 7A
chr5_+_139027877 0.167 ENST00000302517.3
 CXXC5
CXXC finger protein 5
chr5_+_139028510 0.166 ENST00000502336.1
ENST00000520967.1
ENST00000511048.1
 CXXC5


CXXC finger protein 5


chr3_+_69985734 0.164 ENST00000314557.6
ENST00000394351.3
 MITF

microphthalmia-associated transcription factor

chr18_+_39535152 0.163 ENST00000262039.4
ENST00000398870.3
ENST00000586545.1
 PIK3C3


phosphatidylinositol 3-kinase, catalytic subunit type 3


chr9_+_42671887 0.145 ENST00000456520.1
ENST00000377391.3
 CBWD7

COBW domain containing 7

chr17_-_39324424 0.131 ENST00000391356.2
 KRTAP4-3
keratin associated protein 4-3
chr13_-_41240717 0.128 ENST00000379561.5
 FOXO1
forkhead box O1
chr4_+_129730947 0.125 ENST00000452328.2
ENST00000504089.1
 PHF17

jade family PHD finger 1

chr15_+_96876340 0.117 ENST00000453270.2
 NR2F2
nuclear receptor subfamily 2, group F, member 2
chr1_+_220701456 0.115 ENST00000366918.4
ENST00000402574.1
 MARK1

MAP/microtubule affinity-regulating kinase 1

chr17_-_63557309 0.105 ENST00000580513.1
 AXIN2
axin 2
chr9_+_130853715 0.104 ENST00000373066.5
ENST00000432073.2
 SLC25A25

solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25

chr12_+_54891495 0.090 ENST00000293373.6
 NCKAP1L
NCK-associated protein 1-like
chr4_+_78804393 0.077 ENST00000502384.1
 MRPL1
mitochondrial ribosomal protein L1
chr21_+_35552978 0.076 ENST00000428914.2
ENST00000609062.1
ENST00000609947.1
 LINC00310


long intergenic non-protein coding RNA 310


chrX_-_138724677 0.073 ENST00000370573.4
ENST00000338585.6
ENST00000370576.4
 MCF2


MCF.2 cell line derived transforming sequence


chr20_+_56964169 0.073 ENST00000475243.1
 VAPB
VAMP (vesicle-associated membrane protein)-associated protein B and C
chr7_+_27282319 0.069 ENST00000222761.3
 EVX1
even-skipped homeobox 1
chr7_+_123488124 0.067 ENST00000476325.1
 HYAL4
hyaluronoglucosaminidase 4
chr8_+_85095769 0.067 ENST00000518566.1
 RALYL
RALY RNA binding protein-like
chrM_+_4431 0.058 ENST00000361453.3
 MT-ND2
mitochondrially encoded NADH dehydrogenase 2
chr10_-_4285923 0.057 ENST00000418372.1
ENST00000608792.1
 LINC00702

long intergenic non-protein coding RNA 702

chr3_+_69985792 0.054 ENST00000531774.1
 MITF
microphthalmia-associated transcription factor
chr2_-_191878162 0.054 ENST00000540176.1
 STAT1
signal transducer and activator of transcription 1, 91kDa
chr3_-_58523010 0.052 ENST00000459701.2
ENST00000302819.5
 ACOX2

acyl-CoA oxidase 2, branched chain

chr2_+_177015122 0.050 ENST00000468418.3
 HOXD3
homeobox D3
chr17_+_41561317 0.048 ENST00000540306.1
ENST00000262415.3
ENST00000605777.1
 DHX8


DEAH (Asp-Glu-Ala-His) box polypeptide 8


chr1_+_214161272 0.044 ENST00000498508.2
ENST00000366958.4
 PROX1

prospero homeobox 1

chr17_-_42295870 0.041 ENST00000526094.1
ENST00000529383.1
ENST00000530828.1
 UBTF


upstream binding transcription factor, RNA polymerase I


chr12_+_25205666 0.039 ENST00000547044.1
 LRMP
lymphoid-restricted membrane protein
chr1_-_12677714 0.027 ENST00000376223.2
 DHRS3
dehydrogenase/reductase (SDR family) member 3
chr4_+_88754069 0.024 ENST00000395102.4
ENST00000497649.2
 MEPE

matrix extracellular phosphoglycoprotein

chr4_+_88754113 0.022 ENST00000560249.1
ENST00000540395.1
ENST00000511670.1
ENST00000361056.3
 MEPE



matrix extracellular phosphoglycoprotein



chr3_+_141105705 0.021 ENST00000513258.1
 ZBTB38
zinc finger and BTB domain containing 38
chr19_-_12833164 0.020 ENST00000356861.5
 TNPO2
transportin 2
chr12_+_25205446 0.016 ENST00000557489.1
ENST00000354454.3
ENST00000536173.1
 LRMP


lymphoid-restricted membrane protein


chr1_-_161008697 0.015 ENST00000318289.10
ENST00000368023.3
ENST00000368024.1
ENST00000423014.2
 TSTD1



thiosulfate sulfurtransferase (rhodanese)-like domain containing 1



chr17_-_58042075 0.013 ENST00000305783.8
ENST00000589113.1
ENST00000442346.2
 RNFT1


ring finger protein, transmembrane 1


chr10_-_52645416 0.010 ENST00000374001.2
ENST00000373997.3
ENST00000373995.3
ENST00000282641.2
ENST00000395495.1
ENST00000414883.1
 A1CF





APOBEC1 complementation factor





chr10_-_52645379 0.009 ENST00000395489.2
 A1CF
APOBEC1 complementation factor
chr8_-_145754428 0.008 ENST00000527462.1
ENST00000313465.5
ENST00000524821.1
 C8orf82


chromosome 8 open reading frame 82


chr13_-_47471155 0.007 ENST00000543956.1
ENST00000542664.1
 HTR2A

5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled

chr8_-_116680833 0.006 ENST00000220888.5
 TRPS1
trichorhinophalangeal syndrome I
chr6_-_135271219 0.004 ENST00000367847.2
ENST00000367845.2
 ALDH8A1

aldehyde dehydrogenase 8 family, member A1


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.1 0.4 GO:0061181 regulation of chondrocyte development(GO:0061181)
0.0 0.2 GO:2000334 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.0 0.1 GO:0009956 radial pattern formation(GO:0009956)
0.0 0.1 GO:1902617 response to fluoride(GO:1902617)
0.0 0.7 GO:0006825 copper ion transport(GO:0006825)
0.0 1.0 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 0.2 GO:0030242 pexophagy(GO:0030242)
0.0 0.1 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.0 0.1 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.0 0.0 GO:0060849 regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
0.0 0.1 GO:0046725 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308)
0.0 0.1 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:1990111 spermatoproteasome complex(GO:1990111)
0.1 0.2 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.0 0.5 GO:0032039 integrator complex(GO:0032039)
0.0 0.4 GO:0030877 beta-catenin destruction complex(GO:0030877)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.2 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.0 0.1 GO:0033149 FFAT motif binding(GO:0033149)
0.0 0.7 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.4 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.5 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.1 GO:0016402 pristanoyl-CoA oxidase activity(GO:0016402)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 PID_BETA_CATENIN_DEG_PATHWAY Degradation of beta catenin

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 REACTOME_METAL_ION_SLC_TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.5 REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.2 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_LATE_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane