Motif ID: ZNF350

Z-value: 0.526


Transcription factors associated with ZNF350:

Gene SymbolEntrez IDGene Name
ZNF350 ENSG00000256683.2 ZNF350

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
ZNF350hg19_v2_chr19_-_52489923_524901130.433.7e-02Click!


Activity profile for motif ZNF350.

activity profile for motif ZNF350


Sorted Z-values histogram for motif ZNF350

Sorted Z-values for motif ZNF350



Network of associatons between targets according to the STRING database.



First level regulatory network of ZNF350

PNG image of the network

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Top targets:


Showing 1 to 20 of 108 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_+_132286754 2.348 ENST00000434330.1
 CCDC74A
coiled-coil domain containing 74A
chr2_+_132287237 1.949 ENST00000467992.2
 CCDC74A
coiled-coil domain containing 74A
chr4_+_75858290 1.681 ENST00000513238.1
 PARM1
prostate androgen-regulated mucin-like protein 1
chr1_-_46089718 1.525 ENST00000421127.2
ENST00000343901.2
ENST00000528266.1
 CCDC17


coiled-coil domain containing 17


chr17_+_68071389 1.524 ENST00000283936.1
ENST00000392671.1
 KCNJ16

potassium inwardly-rectifying channel, subfamily J, member 16

chr4_+_75858318 1.517 ENST00000307428.7
 PARM1
prostate androgen-regulated mucin-like protein 1
chr17_+_68071458 1.509 ENST00000589377.1
 KCNJ16
potassium inwardly-rectifying channel, subfamily J, member 16
chr3_+_100328433 1.422 ENST00000273352.3
 GPR128
G protein-coupled receptor 128
chr1_-_46089639 1.147 ENST00000445048.2
 CCDC17
coiled-coil domain containing 17
chr16_+_69600209 1.103 ENST00000566899.1
 NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr1_-_98510843 1.043 ENST00000413670.2
ENST00000538428.1
 MIR137HG

MIR137 host gene (non-protein coding)

chr5_+_42423872 0.987 ENST00000230882.4
ENST00000357703.3
 GHR

growth hormone receptor

chr17_+_68165657 0.977 ENST00000243457.3
 KCNJ2
potassium inwardly-rectifying channel, subfamily J, member 2
chr11_-_63381925 0.969 ENST00000415826.1
 PLA2G16
phospholipase A2, group XVI
chr16_+_69600058 0.849 ENST00000393742.2
 NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr20_+_62367989 0.846 ENST00000309546.3
 LIME1
Lck interacting transmembrane adaptor 1
chr2_+_233497931 0.813 ENST00000264059.3
 EFHD1
EF-hand domain family, member D1
chr11_-_45687128 0.570 ENST00000308064.2
 CHST1
carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
chr2_-_157198860 0.559 ENST00000409572.1
 NR4A2
nuclear receptor subfamily 4, group A, member 2
chr12_+_50451331 0.524 ENST00000228468.4
 ASIC1
acid-sensing (proton-gated) ion channel 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 33 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 3.2 GO:0051973 positive regulation of telomerase activity(GO:0051973)
0.1 3.0 GO:0010107 potassium ion import(GO:0010107)
0.0 2.5 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.1 1.4 GO:0046485 ether lipid metabolic process(GO:0046485)
0.3 1.0 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.2 1.0 GO:0000255 allantoin metabolic process(GO:0000255)
0.1 1.0 GO:0050915 sensory perception of sour taste(GO:0050915)
0.0 0.8 GO:0032988 ribonucleoprotein complex disassembly(GO:0032988)
0.0 0.7 GO:0032897 negative regulation of viral transcription(GO:0032897)
0.2 0.6 GO:0021986 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.0 0.6 GO:0006012 galactose metabolic process(GO:0006012)
0.0 0.5 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.0 0.4 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.4 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.3 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.1 0.2 GO:0051097 negative regulation of helicase activity(GO:0051097)
0.0 0.2 GO:0010986 positive regulation of lipoprotein particle clearance(GO:0010986)
0.0 0.2 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.0 0.2 GO:0007386 compartment pattern specification(GO:0007386)
0.0 0.2 GO:0008090 retrograde axonal transport(GO:0008090)

Gene overrepresentation in cellular_component category:

Showing 1 to 12 of 12 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 4.0 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 3.5 GO:0005770 late endosome(GO:0005770)
0.0 1.4 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.3 1.0 GO:0070195 growth hormone receptor complex(GO:0070195)
0.2 0.8 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.1 0.2 GO:0031673 H zone(GO:0031673)
0.0 0.2 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.2 GO:0090543 Flemming body(GO:0090543)
0.0 0.1 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 0.1 GO:0097454 Schwann cell microvillus(GO:0097454)
0.0 0.1 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.1 GO:0070765 gamma-secretase complex(GO:0070765)

Gene overrepresentation in molecular_function category:

Showing 1 to 19 of 19 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 4.0 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.3 1.4 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.2 1.0 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.0 1.0 GO:0070064 proline-rich region binding(GO:0070064)
0.1 0.7 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
0.1 0.6 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 0.6 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.2 0.5 GO:0004947 bradykinin receptor activity(GO:0004947)
0.1 0.5 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.4 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.3 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.1 0.2 GO:0090541 MIT domain binding(GO:0090541)
0.1 0.2 GO:0043398 HLH domain binding(GO:0043398)
0.1 0.2 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.2 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.2 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.2 GO:0008035 high-density lipoprotein particle binding(GO:0008035)
0.0 0.2 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.1 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)

Gene overrepresentation in C2:CP category:

Showing 1 to 4 of 4 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 3.5 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 2.0 ST_WNT_CA2_CYCLIC_GMP_PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 1.0 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network
0.0 0.7 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 8 of 8 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 3.9 REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1 1.4 REACTOME_ACYL_CHAIN_REMODELLING_OF_PS Genes involved in Acyl chain remodelling of PS
0.0 1.0 REACTOME_PROLACTIN_RECEPTOR_SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.6 REACTOME_KERATAN_SULFATE_BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 0.4 REACTOME_REVERSIBLE_HYDRATION_OF_CARBON_DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.3 REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.2 REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.2 REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI Genes involved in Pre-NOTCH Processing in Golgi