Motif ID: ZNF384

Z-value: 1.622


Transcription factors associated with ZNF384:

Gene SymbolEntrez IDGene Name
ZNF384 ENSG00000126746.13 ZNF384

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
ZNF384hg19_v2_chr12_-_6798616_67986840.472.2e-02Click!


Activity profile for motif ZNF384.

activity profile for motif ZNF384


Sorted Z-values histogram for motif ZNF384

Sorted Z-values for motif ZNF384



Network of associatons between targets according to the STRING database.



First level regulatory network of ZNF384

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_-_197676740 4.551 ENST00000452735.1
ENST00000453254.1
ENST00000455191.1
IQCG


IQ motif containing G


chr6_+_116937636 4.485 ENST00000368581.4
ENST00000229554.5
ENST00000368580.4
RSPH4A


radial spoke head 4 homolog A (Chlamydomonas)


chr1_+_38022572 4.480 ENST00000541606.1
DNALI1
dynein, axonemal, light intermediate chain 1
chr3_+_100354442 4.325 ENST00000475887.1
GPR128
G protein-coupled receptor 128
chr12_-_58329819 3.875 ENST00000551421.1
RP11-620J15.3
RP11-620J15.3
chr1_-_109655377 3.732 ENST00000369948.3
C1orf194
chromosome 1 open reading frame 194
chr16_-_28621353 3.716 ENST00000567512.1
SULT1A1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr3_+_63638339 3.659 ENST00000343837.3
ENST00000469440.1
SNTN

sentan, cilia apical structure protein

chr16_+_80574854 3.608 ENST00000305904.6
ENST00000568035.1
DYNLRB2

dynein, light chain, roadblock-type 2

chr1_-_109655355 3.601 ENST00000369945.3
C1orf194
chromosome 1 open reading frame 194
chrY_+_2709527 3.534 ENST00000250784.8
RPS4Y1
ribosomal protein S4, Y-linked 1
chr1_-_159869912 3.425 ENST00000368099.4
CCDC19
coiled-coil domain containing 19
chr16_+_84209539 3.371 ENST00000569735.1
DNAAF1
dynein, axonemal, assembly factor 1
chr1_+_38022513 3.072 ENST00000296218.7
DNALI1
dynein, axonemal, light intermediate chain 1
chr1_-_161337662 3.043 ENST00000367974.1
C1orf192
chromosome 1 open reading frame 192
chr21_-_43735628 3.015 ENST00000291525.10
ENST00000518498.1
TFF3

trefoil factor 3 (intestinal)

chr19_+_55888186 3.009 ENST00000291934.3
TMEM190
transmembrane protein 190
chrX_+_106449862 2.967 ENST00000372453.3
ENST00000535523.1
PIH1D3

PIH1 domain containing 3

chr5_-_35938674 2.878 ENST00000397366.1
ENST00000513623.1
ENST00000514524.1
ENST00000397367.2
CAPSL



calcyphosine-like



chr10_-_75118471 2.813 ENST00000340329.3
TTC18
tetratricopeptide repeat domain 18

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 537 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 19.9 GO:0035082 axoneme assembly(GO:0035082)
0.8 8.4 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.1 7.4 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.2 7.1 GO:0051923 sulfation(GO:0051923)
0.2 6.1 GO:0003341 cilium movement(GO:0003341)
0.2 5.3 GO:0031055 chromatin remodeling at centromere(GO:0031055) CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
1.7 5.1 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.5 4.9 GO:0007288 sperm axoneme assembly(GO:0007288)
1.3 3.8 GO:0006174 dADP phosphorylation(GO:0006174) dGDP phosphorylation(GO:0006186) AMP phosphorylation(GO:0006756) CDP phosphorylation(GO:0061508) dAMP phosphorylation(GO:0061565) CMP phosphorylation(GO:0061566) dCMP phosphorylation(GO:0061567) GDP phosphorylation(GO:0061568) UDP phosphorylation(GO:0061569) dCDP phosphorylation(GO:0061570) TDP phosphorylation(GO:0061571)
0.0 3.7 GO:0000209 protein polyubiquitination(GO:0000209)
0.1 3.5 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.4 3.3 GO:1990504 dense core granule exocytosis(GO:1990504)
1.0 3.0 GO:0003147 neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713)
0.5 2.7 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.2 2.7 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.1 2.6 GO:0006999 nuclear pore organization(GO:0006999)
0.8 2.5 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.5 2.5 GO:0019303 D-ribose catabolic process(GO:0019303)
0.1 2.5 GO:0072189 ureter development(GO:0072189)
0.1 2.3 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 216 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 23.2 GO:0097014 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0 7.9 GO:0005929 cilium(GO:0005929)
0.1 7.4 GO:0005814 centriole(GO:0005814)
0.0 7.1 GO:0000151 ubiquitin ligase complex(GO:0000151)
2.3 6.8 GO:0001534 radial spoke(GO:0001534)
0.6 6.8 GO:0036157 outer dynein arm(GO:0036157)
0.8 5.9 GO:0002177 manchette(GO:0002177)
0.3 5.0 GO:0036038 MKS complex(GO:0036038)
0.2 4.2 GO:0042613 MHC class II protein complex(GO:0042613)
0.3 4.0 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.2 3.8 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.1 3.3 GO:0030992 intraciliary transport particle B(GO:0030992)
0.6 3.0 GO:0002079 inner acrosomal membrane(GO:0002079)
0.1 2.4 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 2.3 GO:0031901 early endosome membrane(GO:0031901)
0.1 2.0 GO:0005721 pericentric heterochromatin(GO:0005721)
0.2 1.9 GO:0036128 CatSper complex(GO:0036128)
0.2 1.9 GO:0097255 R2TP complex(GO:0097255)
0.1 1.9 GO:0097433 dense body(GO:0097433)
0.1 1.9 GO:0034451 centriolar satellite(GO:0034451)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 340 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 13.0 GO:0045504 dynein heavy chain binding(GO:0045504)
0.1 6.7 GO:0030544 Hsp70 protein binding(GO:0030544)
1.3 5.1 GO:0004031 aldehyde oxidase activity(GO:0004031)
0.6 4.1 GO:0050294 flavonol 3-sulfotransferase activity(GO:0047894) steroid sulfotransferase activity(GO:0050294)
0.1 4.1 GO:0070840 dynein complex binding(GO:0070840)
0.3 4.0 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1 3.9 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.2 3.7 GO:0070330 aromatase activity(GO:0070330)
0.3 3.5 GO:0050145 nucleoside phosphate kinase activity(GO:0050145)
0.1 3.2 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 3.2 GO:0004386 helicase activity(GO:0004386)
0.2 3.0 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.1 2.9 GO:0008009 chemokine activity(GO:0008009)
0.7 2.8 GO:0061714 folic acid receptor activity(GO:0061714)
0.5 2.5 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.3 2.5 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 2.5 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 2.5 GO:0043621 protein self-association(GO:0043621)
0.0 2.3 GO:0004004 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)
0.1 2.2 GO:0019200 carbohydrate kinase activity(GO:0019200)

Gene overrepresentation in C2:CP category:

Showing 1 to 20 of 41 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 4.0 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.0 3.7 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.2 2.9 PID_ALK2_PATHWAY ALK2 signaling events
0.0 1.8 PID_HIF1A_PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 1.8 PID_E2F_PATHWAY E2F transcription factor network
0.0 1.7 PID_PLK1_PATHWAY PLK1 signaling events
0.0 1.6 PID_BARD1_PATHWAY BARD1 signaling events
0.1 1.5 PID_THROMBIN_PAR4_PATHWAY PAR4-mediated thrombin signaling events
0.0 1.5 PID_BMP_PATHWAY BMP receptor signaling
0.0 1.5 PID_MYC_REPRESS_PATHWAY Validated targets of C-MYC transcriptional repression
0.0 1.4 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4
0.0 1.1 PID_RAS_PATHWAY Regulation of Ras family activation
0.0 1.1 PID_RHOA_REG_PATHWAY Regulation of RhoA activity
0.0 1.0 PID_MYC_PATHWAY C-MYC pathway
0.0 1.0 PID_TRAIL_PATHWAY TRAIL signaling pathway
0.0 1.0 PID_CMYB_PATHWAY C-MYB transcription factor network
0.0 0.9 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.0 0.8 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.6 PID_ATF2_PATHWAY ATF-2 transcription factor network
0.0 0.6 PID_RAC1_PATHWAY RAC1 signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 77 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 6.3 REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.4 5.4 REACTOME_ETHANOL_OXIDATION Genes involved in Ethanol oxidation
0.1 3.5 REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.1 3.1 REACTOME_NEP_NS2_INTERACTS_WITH_THE_CELLULAR_EXPORT_MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.1 2.8 REACTOME_EXTENSION_OF_TELOMERES Genes involved in Extension of Telomeres
0.1 2.8 REACTOME_IRON_UPTAKE_AND_TRANSPORT Genes involved in Iron uptake and transport
0.0 2.8 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 2.4 REACTOME_GLUTATHIONE_CONJUGATION Genes involved in Glutathione conjugation
0.0 2.4 REACTOME_AUTODEGRADATION_OF_CDH1_BY_CDH1_APC_C Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C
0.2 2.0 REACTOME_DIGESTION_OF_DIETARY_CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.1 2.0 REACTOME_ACTIVATION_OF_GENES_BY_ATF4 Genes involved in Activation of Genes by ATF4
0.1 1.8 REACTOME_TRANSLOCATION_OF_ZAP_70_TO_IMMUNOLOGICAL_SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1 1.7 REACTOME_REGULATION_OF_COMPLEMENT_CASCADE Genes involved in Regulation of Complement cascade
0.0 1.6 REACTOME_OXYGEN_DEPENDENT_PROLINE_HYDROXYLATION_OF_HYPOXIA_INDUCIBLE_FACTOR_ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.1 1.5 REACTOME_IL_7_SIGNALING Genes involved in Interleukin-7 signaling
0.1 1.5 REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 1.5 REACTOME_G1_S_SPECIFIC_TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 1.4 REACTOME_SHC1_EVENTS_IN_ERBB4_SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.1 1.3 REACTOME_REGULATION_OF_THE_FANCONI_ANEMIA_PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 1.3 REACTOME_PHOSPHORYLATION_OF_THE_APC_C Genes involved in Phosphorylation of the APC/C