Motif ID: ZNF691

Z-value: 0.692


Transcription factors associated with ZNF691:

Gene SymbolEntrez IDGene Name
ZNF691 ENSG00000164011.13 ZNF691

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
ZNF691hg19_v2_chr1_+_43312258_43312310-0.368.7e-02Click!


Activity profile for motif ZNF691.

activity profile for motif ZNF691


Sorted Z-values histogram for motif ZNF691

Sorted Z-values for motif ZNF691



Network of associatons between targets according to the STRING database.



First level regulatory network of ZNF691

PNG image of the network

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Top targets:


Showing 1 to 20 of 153 entries
PromoterScoreRefseqGene SymbolGene Name
chr19_-_51472222 3.706 ENST00000376851.3
 KLK6
kallikrein-related peptidase 6
chr19_-_51472031 3.575 ENST00000391808.1
 KLK6
kallikrein-related peptidase 6
chr7_+_134576317 1.093 ENST00000424922.1
ENST00000495522.1
 CALD1

caldesmon 1

chr14_+_55033815 1.081 ENST00000554335.1
 SAMD4A
sterile alpha motif domain containing 4A
chr8_+_27168988 1.074 ENST00000397501.1
ENST00000338238.4
ENST00000544172.1
 PTK2B


protein tyrosine kinase 2 beta


chr6_+_151186554 0.921 ENST00000367321.3
ENST00000367307.4
 MTHFD1L

methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like

chr6_-_144329531 0.840 ENST00000429150.1
ENST00000392309.1
ENST00000416623.1
ENST00000392307.1
 PLAGL1



pleiomorphic adenoma gene-like 1



chr1_-_147232669 0.823 ENST00000369237.1
 GJA5
gap junction protein, alpha 5, 40kDa
chr14_+_55034330 0.817 ENST00000251091.5
 SAMD4A
sterile alpha motif domain containing 4A
chr11_-_5323226 0.781 ENST00000380224.1
 OR51B4
olfactory receptor, family 51, subfamily B, member 4
chr7_+_134576151 0.764 ENST00000393118.2
 CALD1
caldesmon 1
chr11_+_5410607 0.701 ENST00000328611.3
 OR51M1
olfactory receptor, family 51, subfamily M, member 1
chr1_+_28199047 0.691 ENST00000373925.1
ENST00000328928.7
ENST00000373927.3
ENST00000427466.1
ENST00000442118.1
ENST00000373921.3
 THEMIS2





thymocyte selection associated family member 2





chr7_-_143059780 0.680 ENST00000409578.1
ENST00000409346.1
 FAM131B

family with sequence similarity 131, member B

chr2_+_238475217 0.635 ENST00000165524.1
 PRLH
prolactin releasing hormone
chr1_+_11994715 0.621 ENST00000449038.1
ENST00000376369.3
ENST00000429000.2
ENST00000196061.4
 PLOD1



procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1



chr9_+_139553306 0.621 ENST00000371699.1
 EGFL7
EGF-like-domain, multiple 7
chr12_-_51717875 0.602 ENST00000604560.1
 BIN2
bridging integrator 2
chr15_-_83018198 0.581 ENST00000557886.1
 RP13-996F3.4
golgin A6 family-like 19
chr12_-_51717948 0.567 ENST00000267012.4
 BIN2
bridging integrator 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 42 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 7.3 GO:0016540 protein autoprocessing(GO:0016540)
0.1 2.1 GO:0097320 membrane tubulation(GO:0097320)
0.0 1.9 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 1.6 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.3 1.1 GO:0010752 regulation of cGMP-mediated signaling(GO:0010752) regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
0.2 0.9 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.3 0.8 GO:0003193 pulmonary valve formation(GO:0003193) regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652) foramen ovale closure(GO:0035922) regulation of bundle of His cell action potential(GO:0098905)
0.2 0.7 GO:0001188 RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
0.2 0.6 GO:0002023 reduction of food intake in response to dietary excess(GO:0002023)
0.2 0.6 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.0 0.6 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.2 0.5 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.1 0.4 GO:0032185 septin cytoskeleton organization(GO:0032185)
0.1 0.4 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.1 0.4 GO:0039663 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.0 0.4 GO:0043320 natural killer cell degranulation(GO:0043320)
0.0 0.4 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.4 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 0.4 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.1 0.3 GO:0035552 oxidative single-stranded DNA demethylation(GO:0035552)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 20 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.1 GO:0001891 phagocytic cup(GO:0001891)
0.1 1.9 GO:0030478 actin cap(GO:0030478)
0.0 1.9 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.1 1.1 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.8 GO:0005922 connexon complex(GO:0005922)
0.0 0.7 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.6 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.4 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.4 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.4 GO:0031105 septin complex(GO:0031105)
0.0 0.4 GO:0032982 myosin filament(GO:0032982)
0.1 0.3 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.1 0.3 GO:0071797 LUBAC complex(GO:0071797)
0.1 0.3 GO:0071817 MMXD complex(GO:0071817)
0.0 0.3 GO:0005638 lamin filament(GO:0005638)
0.0 0.3 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.3 GO:0033010 paranodal junction(GO:0033010)
0.0 0.2 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.2 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.1 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 33 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 7.1 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 1.9 GO:0005523 tropomyosin binding(GO:0005523)
0.0 1.9 GO:0030371 translation repressor activity(GO:0030371)
0.0 1.6 GO:0004984 olfactory receptor activity(GO:0004984)
0.4 1.1 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.2 0.9 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.2 0.8 GO:0086020 gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling(GO:0086020)
0.0 0.7 GO:0001054 RNA polymerase I activity(GO:0001054)
0.2 0.6 GO:0033823 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
0.0 0.6 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.2 0.5 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.0 0.5 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.5 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.0 0.4 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.4 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.4 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.4 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.4 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0 0.4 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 0.4 GO:0004602 glutathione peroxidase activity(GO:0004602)

Gene overrepresentation in C2:CP category:

Showing 1 to 2 of 2 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 8.4 PID_ALPHA_SYNUCLEIN_PATHWAY Alpha-synuclein signaling
0.0 0.4 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 9 of 9 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.9 REACTOME_SMOOTH_MUSCLE_CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 1.1 REACTOME_SIGNAL_REGULATORY_PROTEIN_SIRP_FAMILY_INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 1.1 REACTOME_OLFACTORY_SIGNALING_PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.8 REACTOME_GAP_JUNCTION_ASSEMBLY Genes involved in Gap junction assembly
0.1 0.4 REACTOME_BINDING_AND_ENTRY_OF_HIV_VIRION Genes involved in Binding and entry of HIV virion
0.0 0.4 REACTOME_DOWNREGULATION_OF_ERBB2_ERBB3_SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.2 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.2 REACTOME_ADENYLATE_CYCLASE_ACTIVATING_PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.2 REACTOME_IKK_COMPLEX_RECRUITMENT_MEDIATED_BY_RIP1 Genes involved in IKK complex recruitment mediated by RIP1