Motif ID: ZNF784
Z-value: 0.925
Transcription factors associated with ZNF784:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| ZNF784 | ENSG00000179922.5 | ZNF784 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| ZNF784 | hg19_v2_chr19_-_56135928_56135967 | -0.60 | 2.0e-03 | Click! |
Top targets:
Showing 1 to 20 of 200 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 124 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 7.8 | GO:0031581 | hemidesmosome assembly(GO:0031581) |
| 0.5 | 5.8 | GO:0060753 | regulation of mast cell chemotaxis(GO:0060753) |
| 0.0 | 5.7 | GO:0016197 | endosomal transport(GO:0016197) |
| 0.6 | 3.5 | GO:0007079 | mitotic chromosome movement towards spindle pole(GO:0007079) |
| 0.0 | 3.1 | GO:0018149 | peptide cross-linking(GO:0018149) |
| 0.7 | 2.9 | GO:0051754 | meiotic sister chromatid cohesion, centromeric(GO:0051754) |
| 0.2 | 2.9 | GO:1902172 | keratinocyte apoptotic process(GO:0097283) regulation of keratinocyte apoptotic process(GO:1902172) |
| 0.1 | 2.9 | GO:0035235 | ionotropic glutamate receptor signaling pathway(GO:0035235) |
| 0.0 | 2.9 | GO:0070268 | cornification(GO:0070268) |
| 0.6 | 2.8 | GO:0061143 | alveolar primary septum development(GO:0061143) |
| 0.1 | 2.5 | GO:0045741 | positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) |
| 0.1 | 2.5 | GO:0035020 | regulation of Rac protein signal transduction(GO:0035020) |
| 0.2 | 2.4 | GO:0010991 | negative regulation of SMAD protein complex assembly(GO:0010991) |
| 0.1 | 2.2 | GO:0090179 | planar cell polarity pathway involved in neural tube closure(GO:0090179) |
| 0.7 | 2.1 | GO:0033242 | regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283) |
| 0.7 | 2.0 | GO:0090271 | positive regulation of fibroblast growth factor production(GO:0090271) |
| 0.6 | 1.9 | GO:2001037 | tongue muscle cell differentiation(GO:0035981) positive regulation of skeletal muscle fiber differentiation(GO:1902811) regulation of tongue muscle cell differentiation(GO:2001035) positive regulation of tongue muscle cell differentiation(GO:2001037) |
| 0.4 | 1.9 | GO:1903285 | negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470) |
| 0.3 | 1.9 | GO:0045218 | zonula adherens maintenance(GO:0045218) |
| 0.0 | 1.7 | GO:0000188 | inactivation of MAPK activity(GO:0000188) |
Gene overrepresentation in cellular_component category:
Showing 1 to 20 of 57 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 5.6 | GO:0030670 | phagocytic vesicle membrane(GO:0030670) |
| 0.2 | 5.5 | GO:0030056 | hemidesmosome(GO:0030056) |
| 0.2 | 3.6 | GO:0000940 | condensed chromosome outer kinetochore(GO:0000940) |
| 0.2 | 3.5 | GO:0031616 | spindle pole centrosome(GO:0031616) |
| 0.1 | 3.1 | GO:0001533 | cornified envelope(GO:0001533) |
| 0.0 | 3.0 | GO:0012507 | ER to Golgi transport vesicle membrane(GO:0012507) |
| 0.6 | 2.9 | GO:0098843 | postsynaptic endocytic zone(GO:0098843) |
| 0.1 | 2.5 | GO:0034451 | centriolar satellite(GO:0034451) |
| 0.1 | 2.4 | GO:0097228 | sperm principal piece(GO:0097228) |
| 0.1 | 2.3 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
| 0.0 | 2.2 | GO:0031901 | early endosome membrane(GO:0031901) |
| 0.3 | 2.0 | GO:0005610 | laminin-5 complex(GO:0005610) |
| 0.2 | 1.9 | GO:0005915 | zonula adherens(GO:0005915) |
| 0.0 | 1.8 | GO:0005901 | caveola(GO:0005901) |
| 0.1 | 1.6 | GO:0035371 | microtubule plus-end(GO:0035371) |
| 0.0 | 1.6 | GO:0097014 | axoneme(GO:0005930) ciliary plasm(GO:0097014) |
| 0.4 | 1.4 | GO:0071001 | U4/U6 snRNP(GO:0071001) |
| 0.2 | 1.3 | GO:0031313 | extrinsic component of endosome membrane(GO:0031313) |
| 0.1 | 1.3 | GO:0005583 | fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643) |
| 0.2 | 1.1 | GO:0032437 | cuticular plate(GO:0032437) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 88 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 6.1 | GO:0019887 | protein kinase regulator activity(GO:0019887) |
| 0.2 | 5.6 | GO:0001871 | pattern binding(GO:0001871) polysaccharide binding(GO:0030247) |
| 0.2 | 3.9 | GO:0008499 | UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499) |
| 0.3 | 3.7 | GO:0038132 | neuregulin binding(GO:0038132) |
| 0.1 | 3.6 | GO:0050699 | WW domain binding(GO:0050699) |
| 0.2 | 2.9 | GO:0004971 | AMPA glutamate receptor activity(GO:0004971) |
| 0.0 | 2.9 | GO:0004869 | cysteine-type endopeptidase inhibitor activity(GO:0004869) |
| 0.1 | 2.8 | GO:0051183 | vitamin transporter activity(GO:0051183) |
| 0.0 | 2.8 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
| 0.0 | 2.6 | GO:0031490 | chromatin DNA binding(GO:0031490) |
| 0.1 | 2.4 | GO:0030506 | ankyrin binding(GO:0030506) |
| 0.7 | 2.1 | GO:0036487 | nitric-oxide synthase inhibitor activity(GO:0036487) |
| 0.1 | 2.1 | GO:0000146 | microfilament motor activity(GO:0000146) |
| 0.4 | 1.9 | GO:0060961 | phospholipase D inhibitor activity(GO:0060961) |
| 0.4 | 1.9 | GO:0008401 | retinoic acid 4-hydroxylase activity(GO:0008401) |
| 0.1 | 1.9 | GO:0008569 | ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569) |
| 0.4 | 1.8 | GO:0004666 | prostaglandin-endoperoxide synthase activity(GO:0004666) |
| 0.0 | 1.6 | GO:0005154 | epidermal growth factor receptor binding(GO:0005154) |
| 0.2 | 1.4 | GO:0030621 | U4 snRNA binding(GO:0030621) |
| 0.1 | 1.3 | GO:0016206 | catechol O-methyltransferase activity(GO:0016206) |
Gene overrepresentation in C2:CP category:
Showing 1 to 20 of 23 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 6.7 | PID_INTEGRIN4_PATHWAY | Alpha6 beta4 integrin-ligand interactions |
| 0.1 | 5.8 | PID_IL8_CXCR2_PATHWAY | IL8- and CXCR2-mediated signaling events |
| 0.0 | 5.6 | NABA_ECM_GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.1 | 3.5 | PID_AURORA_A_PATHWAY | Aurora A signaling |
| 0.1 | 2.9 | PID_NCADHERIN_PATHWAY | N-cadherin signaling events |
| 0.1 | 2.4 | PID_ERBB_NETWORK_PATHWAY | ErbB receptor signaling network |
| 0.0 | 2.4 | NABA_PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.1 | 2.0 | PID_S1P_S1P1_PATHWAY | S1P1 pathway |
| 0.0 | 2.0 | PID_TGFBR_PATHWAY | TGF-beta receptor signaling |
| 0.0 | 1.9 | PID_ALPHA_SYNUCLEIN_PATHWAY | Alpha-synuclein signaling |
| 0.0 | 1.9 | PID_ECADHERIN_STABILIZATION_PATHWAY | Stabilization and expansion of the E-cadherin adherens junction |
| 0.0 | 1.7 | PID_EPHRINB_REV_PATHWAY | Ephrin B reverse signaling |
| 0.0 | 1.7 | PID_NETRIN_PATHWAY | Netrin-mediated signaling events |
| 0.0 | 1.1 | PID_ATM_PATHWAY | ATM pathway |
| 0.0 | 0.8 | PID_P38_ALPHA_BETA_PATHWAY | Regulation of p38-alpha and p38-beta |
| 0.0 | 0.7 | PID_AURORA_B_PATHWAY | Aurora B signaling |
| 0.0 | 0.5 | NABA_BASEMENT_MEMBRANES | Genes encoding structural components of basement membranes |
| 0.0 | 0.5 | PID_IL27_PATHWAY | IL27-mediated signaling events |
| 0.0 | 0.4 | SA_B_CELL_RECEPTOR_COMPLEXES | Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases. |
| 0.0 | 0.3 | PID_ARF6_DOWNSTREAM_PATHWAY | Arf6 downstream pathway |
Gene overrepresentation in C2:CP:REACTOME category:
Showing 1 to 20 of 36 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 8.3 | REACTOME_CELL_JUNCTION_ORGANIZATION | Genes involved in Cell junction organization |
| 0.1 | 5.6 | REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE | Genes involved in Sema4D induced cell migration and growth-cone collapse |
| 0.0 | 3.7 | REACTOME_PHASE1_FUNCTIONALIZATION_OF_COMPOUNDS | Genes involved in Phase 1 - Functionalization of compounds |
| 0.1 | 3.6 | REACTOME_INHIBITION_OF_THE_PROTEOLYTIC_ACTIVITY_OF_APC_C_REQUIRED_FOR_THE_ONSET_OF_ANAPHASE_BY_MITOTIC_SPINDLE_CHECKPOINT_COMPONENTS | Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components |
| 0.1 | 2.9 | REACTOME_UNBLOCKING_OF_NMDA_RECEPTOR_GLUTAMATE_BINDING_AND_ACTIVATION | Genes involved in Unblocking of NMDA receptor, glutamate binding and activation |
| 0.1 | 2.2 | REACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING | Genes involved in Downregulation of TGF-beta receptor signaling |
| 0.1 | 2.1 | REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS | Genes involved in Association of TriC/CCT with target proteins during biosynthesis |
| 0.0 | 1.9 | REACTOME_AMYLOIDS | Genes involved in Amyloids |
| 0.1 | 1.6 | REACTOME_GLYCOPROTEIN_HORMONES | Genes involved in Glycoprotein hormones |
| 0.1 | 1.6 | REACTOME_KERATAN_SULFATE_DEGRADATION | Genes involved in Keratan sulfate degradation |
| 0.0 | 1.6 | REACTOME_PHASE_II_CONJUGATION | Genes involved in Phase II conjugation |
| 0.0 | 1.5 | REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION | Genes involved in NOTCH1 Intracellular Domain Regulates Transcription |
| 0.0 | 1.2 | REACTOME_NEPHRIN_INTERACTIONS | Genes involved in Nephrin interactions |
| 0.1 | 1.1 | REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT | Genes involved in G2/M DNA damage checkpoint |
| 0.0 | 1.0 | REACTOME_STRIATED_MUSCLE_CONTRACTION | Genes involved in Striated Muscle Contraction |
| 0.0 | 0.9 | REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN | Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin |
| 0.0 | 0.9 | REACTOME_NCAM1_INTERACTIONS | Genes involved in NCAM1 interactions |
| 0.0 | 0.7 | REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION | Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion |
| 0.0 | 0.7 | REACTOME_CS_DS_DEGRADATION | Genes involved in CS/DS degradation |
| 0.0 | 0.7 | REACTOME_PEROXISOMAL_LIPID_METABOLISM | Genes involved in Peroxisomal lipid metabolism |
