Motif ID: ZSCAN4

Z-value: 0.598


Transcription factors associated with ZSCAN4:

Gene SymbolEntrez IDGene Name
ZSCAN4 ENSG00000180532.6 ZSCAN4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
ZSCAN4hg19_v2_chr19_+_58180303_581803030.048.7e-01Click!


Activity profile for motif ZSCAN4.

activity profile for motif ZSCAN4


Sorted Z-values histogram for motif ZSCAN4

Sorted Z-values for motif ZSCAN4



Network of associatons between targets according to the STRING database.



First level regulatory network of ZSCAN4

PNG image of the network

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Top targets:


Showing 1 to 20 of 184 entries
PromoterScoreRefseqGene SymbolGene Name
chr8_-_23712312 0.730 ENST00000290271.2
 STC1
stanniocalcin 1
chr20_+_23168759 0.568 ENST00000411595.1
 RP4-737E23.2
RP4-737E23.2
chr4_+_74718906 0.559 ENST00000226524.3
 PF4V1
platelet factor 4 variant 1
chr12_-_57634475 0.526 ENST00000393825.1
 NDUFA4L2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
chr12_-_10022735 0.497 ENST00000228438.2
 CLEC2B
C-type lectin domain family 2, member B
chr12_-_96390063 0.476 ENST00000541929.1
 HAL
histidine ammonia-lyase
chr1_-_228603694 0.460 ENST00000366697.2
 TRIM17
tripartite motif containing 17
chr17_-_34207295 0.392 ENST00000463941.1
ENST00000293272.3
 CCL5

chemokine (C-C motif) ligand 5

chr3_-_58572760 0.383 ENST00000447756.2
 FAM107A
family with sequence similarity 107, member A
chr7_-_84569561 0.376 ENST00000439105.1
 AC074183.4
AC074183.4
chr5_-_82969405 0.376 ENST00000510978.1
 HAPLN1
hyaluronan and proteoglycan link protein 1
chr15_-_74374891 0.361 ENST00000290438.3
 GOLGA6A
golgin A6 family, member A
chr15_+_75550940 0.358 ENST00000300576.5
 GOLGA6C
golgin A6 family, member C
chr9_+_128509624 0.355 ENST00000342287.5
ENST00000373487.4
 PBX3

pre-B-cell leukemia homeobox 3

chr5_+_31193847 0.353 ENST00000514738.1
ENST00000265071.2
 CDH6

cadherin 6, type 2, K-cadherin (fetal kidney)

chr14_-_55658252 0.347 ENST00000395425.2
 DLGAP5
discs, large (Drosophila) homolog-associated protein 5
chr2_-_101034070 0.345 ENST00000264249.3
 CHST10
carbohydrate sulfotransferase 10
chr3_-_52569023 0.336 ENST00000307076.4
 NT5DC2
5'-nucleotidase domain containing 2
chr3_+_98482175 0.335 ENST00000485391.1
ENST00000492254.1
 ST3GAL6

ST3 beta-galactoside alpha-2,3-sialyltransferase 6

chr19_+_17516624 0.311 ENST00000596322.1
ENST00000600008.1
ENST00000601885.1
 CTD-2521M24.9


CTD-2521M24.9



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 40 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 0.7 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.1 0.6 GO:0019556 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.0 0.6 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.0 0.5 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.1 0.4 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.1 0.4 GO:0007386 compartment pattern specification(GO:0007386)
0.0 0.4 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.4 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.1 0.3 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
0.0 0.3 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.3 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.3 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1 0.2 GO:1901253 negative regulation of dendritic cell cytokine production(GO:0002731) negative regulation of intracellular transport of viral material(GO:1901253)
0.1 0.2 GO:0033123 positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
0.0 0.2 GO:0036378 alkaloid catabolic process(GO:0009822) calcitriol biosynthetic process from calciol(GO:0036378)
0.0 0.2 GO:0060979 vasculogenesis involved in coronary vascular morphogenesis(GO:0060979)
0.0 0.2 GO:0019075 virus maturation(GO:0019075)
0.0 0.2 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 0.2 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.2 GO:0090043 regulation of tubulin deacetylation(GO:0090043)

Gene overrepresentation in cellular_component category:

Showing 1 to 8 of 8 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.7 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 0.4 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.4 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.3 GO:0031262 Ndc80 complex(GO:0031262)
0.0 0.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.2 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.2 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.1 GO:0031251 PAN complex(GO:0031251)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 29 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 0.6 GO:0016841 ammonia-lyase activity(GO:0016841)
0.0 0.6 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 0.5 GO:0030197 extracellular matrix constituent, lubricant activity(GO:0030197)
0.0 0.5 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.4 GO:0005502 11-cis retinal binding(GO:0005502)
0.1 0.4 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.0 0.4 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.3 GO:0052798 beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798)
0.1 0.3 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.0 0.3 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.3 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 0.2 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.2 GO:0004967 glucagon receptor activity(GO:0004967)
0.0 0.2 GO:0070643 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.0 0.2 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.2 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.2 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.2 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.1 GO:0008746 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)

Gene overrepresentation in C2:CP category:

Showing 1 to 2 of 2 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.7 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.3 PID_CONE_PATHWAY Visual signal transduction: Cones

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 8 of 8 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.6 REACTOME_COMMON_PATHWAY Genes involved in Common Pathway
0.0 0.5 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.4 REACTOME_OPSINS Genes involved in Opsins
0.0 0.4 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.3 REACTOME_ROLE_OF_SECOND_MESSENGERS_IN_NETRIN1_SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.3 REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.3 REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.2 REACTOME_XENOBIOTICS Genes involved in Xenobiotics