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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for AGCAGCG

Z-value: 0.69

Motif logo

miRNA associated with seed AGCAGCG

NamemiRBASE accession
MIMAT0002874

Activity profile of AGCAGCG motif

Sorted Z-values of AGCAGCG motif

Network of associatons between targets according to the STRING database.

First level regulatory network of AGCAGCG

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr2_-_72147819 3.29 ENST00000001146.7
ENST00000546307.5
ENST00000474509.1
cytochrome P450 family 26 subfamily B member 1
chr12_+_4273751 3.24 ENST00000675880.1
ENST00000261254.8
cyclin D2
chr3_-_13880059 2.06 ENST00000285018.5
Wnt family member 7A
chr15_+_69414304 1.95 ENST00000352331.8
ENST00000679126.1
ENST00000647715.1
ENST00000559279.6
kinesin family member 23
chr11_+_125626229 1.93 ENST00000532449.6
ENST00000534070.5
checkpoint kinase 1
chr17_+_59155726 1.90 ENST00000578777.5
ENST00000577457.1
ENST00000582995.5
ENST00000262293.9
ENST00000614081.1
proline rich 11
chr8_+_25459190 1.75 ENST00000380665.3
ENST00000330560.8
cell division cycle associated 2
chr8_+_28701487 1.58 ENST00000220562.9
exostosin like glycosyltransferase 3
chr11_-_119729158 1.47 ENST00000264025.8
nectin cell adhesion molecule 1
chr7_-_99144053 1.36 ENST00000361125.1
ENST00000361368.7
SMAD specific E3 ubiquitin protein ligase 1
chr7_+_36389852 1.24 ENST00000265748.7
anillin actin binding protein
chr1_-_243850070 1.21 ENST00000366539.6
ENST00000672578.1
AKT serine/threonine kinase 3
chr2_+_200811882 1.19 ENST00000409600.6
basic leucine zipper and W2 domains 1
chr19_-_50511146 1.16 ENST00000594350.1
ENST00000601423.5
Josephin domain containing 2
chr11_-_65900413 1.15 ENST00000448083.6
ENST00000531493.5
ENST00000532401.1
FOS like 1, AP-1 transcription factor subunit
chr3_+_150408314 1.11 ENST00000361875.7
TSC22 domain family member 2
chr12_-_7936177 1.09 ENST00000544291.1
ENST00000075120.12
solute carrier family 2 member 3
chr15_-_52529050 1.05 ENST00000399231.7
myosin VA
chr15_+_66386902 1.01 ENST00000307102.10
mitogen-activated protein kinase kinase 1
chr6_+_20401864 1.00 ENST00000346618.8
ENST00000613242.4
E2F transcription factor 3
chr12_-_107761113 0.91 ENST00000228437.10
PR/SET domain 4
chr19_-_50637939 0.89 ENST00000338916.8
synaptotagmin 3
chr9_-_27529705 0.89 ENST00000262244.6
MOB kinase activator 3B
chr3_-_48188356 0.88 ENST00000351231.7
ENST00000437972.1
ENST00000302506.8
cell division cycle 25A
chr15_+_38252792 0.87 ENST00000299084.9
sprouty related EVH1 domain containing 1
chr2_+_28392802 0.84 ENST00000379619.5
ENST00000264716.9
FOS like 2, AP-1 transcription factor subunit
chr17_+_32486975 0.81 ENST00000313401.4
cyclin dependent kinase 5 regulatory subunit 1
chr12_-_7872843 0.78 ENST00000340749.9
ENST00000535295.5
ENST00000539234.5
solute carrier family 2 member 14
chr1_+_65147514 0.77 ENST00000545314.5
adenylate kinase 4
chr9_+_35749274 0.75 ENST00000378078.5
RGP1 homolog, RAB6A GEF complex partner 1
chr14_+_24398986 0.75 ENST00000382554.4
NYN domain and retroviral integrase containing
chr1_-_119648165 0.74 ENST00000421812.3
zinc finger protein 697
chr2_+_207711631 0.70 ENST00000295414.8
ENST00000420822.1
ENST00000339882.9
cyclin Y like 1
chr14_+_30559142 0.69 ENST00000550944.5
ENST00000438909.6
ENST00000206595.11
ENST00000553504.5
G2/M-phase specific E3 ubiquitin protein ligase
chrX_+_53082358 0.67 ENST00000375442.8
ENST00000579390.1
TSPY like 2
chr22_-_41621014 0.66 ENST00000263256.7
desumoylating isopeptidase 1
chr5_+_157743703 0.65 ENST00000286307.6
LSM11, U7 small nuclear RNA associated
chr9_-_92670124 0.64 ENST00000287996.8
inositol-pentakisphosphate 2-kinase
chr2_-_46462 0.63 ENST00000327669.5
family with sequence similarity 110 member C
chr3_-_123884290 0.63 ENST00000346322.9
ENST00000360772.7
ENST00000360304.8
myosin light chain kinase
chr1_+_77779618 0.63 ENST00000370791.7
ENST00000443751.3
ENST00000645756.1
ENST00000643390.1
ENST00000642959.1
mitoguardin 1
chr8_+_94641145 0.61 ENST00000433389.8
ENST00000358397.9
epithelial splicing regulatory protein 1
chr1_+_109548567 0.61 ENST00000369851.7
G protein subunit alpha i3
chr4_+_127782270 0.61 ENST00000508549.5
ENST00000296464.9
heat shock protein family A (Hsp70) member 4 like
chr11_+_77589911 0.58 ENST00000313578.4
aquaporin 11
chr10_-_118754956 0.56 ENST00000369151.8
CDK2 associated cullin domain 1
chr8_-_91040814 0.54 ENST00000520014.1
ENST00000285419.8
phosphatidylinositol-4,5-bisphosphate 4-phosphatase 2
chr6_+_15246054 0.53 ENST00000341776.7
jumonji and AT-rich interaction domain containing 2
chr3_+_196867856 0.53 ENST00000445299.6
ENST00000323460.10
ENST00000419026.5
SUMO specific peptidase 5
chr9_+_116153783 0.52 ENST00000328252.4
pappalysin 1
chr16_-_88941198 0.51 ENST00000327483.9
ENST00000564416.1
CBFA2/RUNX1 partner transcriptional co-repressor 3
chr19_-_39833615 0.51 ENST00000593685.5
ENST00000600611.5
dual specificity tyrosine phosphorylation regulated kinase 1B
chr2_-_36966503 0.51 ENST00000263918.9
striatin
chr17_-_5584448 0.50 ENST00000269280.8
ENST00000571451.6
ENST00000572272.6
ENST00000613500.4
ENST00000619223.4
ENST00000617618.4
ENST00000345221.7
ENST00000262467.10
NLR family pyrin domain containing 1
chr14_-_105021043 0.50 ENST00000392590.3
ENST00000336219.4
cell division cycle associated 4
chr7_+_4682252 0.50 ENST00000328914.5
forkhead box K1
chr4_-_41748713 0.49 ENST00000226382.4
paired like homeobox 2B
chr16_-_48610150 0.46 ENST00000262384.4
NEDD4 binding protein 1
chr19_-_17688326 0.45 ENST00000552293.5
ENST00000551649.5
ENST00000519716.7
ENST00000550896.1
unc-13 homolog A
chr15_+_58771280 0.44 ENST00000559228.6
ENST00000450403.3
MINDY lysine 48 deubiquitinase 2
chr2_+_203706614 0.43 ENST00000324106.9
CD28 molecule
chr18_+_57352541 0.43 ENST00000324000.4
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
chr14_+_52730154 0.41 ENST00000354586.5
ENST00000442123.6
serine/threonine/tyrosine interacting protein
chr3_-_179071742 0.41 ENST00000311417.7
ENST00000652290.1
zinc finger matrin-type 3
chr9_-_35732122 0.40 ENST00000314888.10
talin 1
chr4_+_122826679 0.40 ENST00000264498.8
fibroblast growth factor 2
chr1_+_180230257 0.39 ENST00000263726.4
LIM homeobox 4
chr5_-_16465757 0.37 ENST00000308683.3
zinc finger protein 622
chr2_+_112275588 0.37 ENST00000409871.6
ENST00000343936.4
zinc finger CCCH-type containing 6
chr2_-_171160833 0.37 ENST00000360843.7
ENST00000431350.7
tousled like kinase 1
chr3_+_189171948 0.37 ENST00000345063.8
tumor protein p63 regulated 1
chr10_+_101354083 0.37 ENST00000408038.6
ENST00000370187.8
beta-transducin repeat containing E3 ubiquitin protein ligase
chr2_-_219543793 0.36 ENST00000243776.11
chondroitin polymerizing factor
chr1_+_2228310 0.35 ENST00000378536.5
SKI proto-oncogene
chr2_-_121285194 0.35 ENST00000263707.6
transcription factor CP2 like 1
chr4_-_76023489 0.34 ENST00000306602.3
C-X-C motif chemokine ligand 10
chr6_+_47477731 0.34 ENST00000359314.5
CD2 associated protein
chrX_+_129540236 0.34 ENST00000371113.9
ENST00000357121.5
OCRL inositol polyphosphate-5-phosphatase
chr7_+_72879349 0.33 ENST00000395270.5
POM121 transmembrane nucleoporin
chr5_+_96662214 0.31 ENST00000395812.6
calpastatin
chr3_+_122184233 0.30 ENST00000638421.1
ENST00000498619.4
calcium sensing receptor
chr12_+_57550027 0.29 ENST00000674619.1
ENST00000676359.1
ENST00000286452.5
ENST00000455537.7
ENST00000676457.1
kinesin family member 5A
chr16_-_23149378 0.28 ENST00000219689.12
ubiquitin specific peptidase 31
chr3_+_10816201 0.28 ENST00000454147.1
ENST00000254488.7
solute carrier family 6 member 11
chr7_+_90403386 0.28 ENST00000287916.8
ENST00000394604.5
ENST00000496677.6
ENST00000394605.2
ENST00000480135.1
claudin 12
novel transcript
chr1_+_184386978 0.28 ENST00000235307.7
chromosome 1 open reading frame 21
chr6_+_127118657 0.26 ENST00000356698.9
R-spondin 3
chr4_+_25234003 0.26 ENST00000264864.8
phosphatidylinositol 4-kinase type 2 beta
chr12_-_109573482 0.25 ENST00000540016.5
ENST00000545712.7
metabolism of cobalamin associated B
chr6_+_41072939 0.25 ENST00000341376.11
ENST00000353205.5
nuclear transcription factor Y subunit alpha
chr3_-_120450981 0.23 ENST00000424703.6
ENST00000469005.1
ENST00000295633.8
follistatin like 1
chr10_+_93893931 0.21 ENST00000371408.7
ENST00000427197.2
solute carrier family 35 member G1
chr18_-_63319987 0.20 ENST00000398117.1
BCL2 apoptosis regulator
chr7_+_139231225 0.20 ENST00000473989.8
ubinuclein 2
chrX_+_118974608 0.19 ENST00000304778.11
ENST00000371628.8
LON peptidase N-terminal domain and ring finger 3
chr1_+_38991239 0.18 ENST00000432648.8
ENST00000446189.6
ENST00000372984.8
akirin 1
chr6_-_96837460 0.17 ENST00000229955.4
G protein-coupled receptor 63
chr10_+_110871903 0.17 ENST00000280154.12
programmed cell death 4
chr5_+_73498408 0.16 ENST00000335895.12
ENST00000678135.1
ENST00000380591.7
ENST00000677654.1
ENST00000507081.6
basic transcription factor 3
chr2_+_61017562 0.16 ENST00000401576.1
ENST00000295030.6
ENST00000414712.2
peroxisomal biogenesis factor 13
chr17_-_64662290 0.16 ENST00000262435.14
SMAD specific E3 ubiquitin protein ligase 2
chr22_+_45163910 0.16 ENST00000347635.9
ENST00000407019.6
ENST00000424634.5
ENST00000417702.5
ENST00000430547.5
nucleoporin 50
chr1_+_201829132 0.15 ENST00000361565.9
importin 9
chr5_+_131264043 0.14 ENST00000505065.2
ENST00000503291.5
ENST00000360515.7
CDC42 small effector 2
chr1_-_47997348 0.14 ENST00000606738.3
TraB domain containing 2B
chr6_+_43076262 0.13 ENST00000476760.1
ENST00000230419.9
ENST00000471863.5
ENST00000345201.6
ENST00000349241.6
ENST00000352931.6
protein tyrosine kinase 7 (inactive)
chr10_-_117375407 0.13 ENST00000334464.7
PDZ domain containing 8
chrX_+_135344784 0.12 ENST00000370761.7
ENST00000339249.5
zinc finger protein 449
chr5_+_154712824 0.12 ENST00000336314.9
La ribonucleoprotein 1, translational regulator
chr4_-_98929092 0.11 ENST00000280892.10
ENST00000511644.5
ENST00000504432.5
ENST00000450253.7
ENST00000505992.1
eukaryotic translation initiation factor 4E
chr17_+_29593118 0.11 ENST00000394859.8
ankyrin repeat domain 13B
chr4_+_165873231 0.11 ENST00000061240.7
tolloid like 1
chr17_+_79778135 0.11 ENST00000310942.9
ENST00000269399.5
chromobox 2
chr13_-_46387447 0.10 ENST00000676051.1
ENST00000378787.7
ENST00000378781.7
ENST00000378797.6
rubicon like autophagy enhancer
chr3_-_129688691 0.10 ENST00000432054.6
transmembrane and coiled-coil domain family 1
chr16_-_46973634 0.10 ENST00000317089.10
DnaJ heat shock protein family (Hsp40) member A2
chr17_+_4997901 0.10 ENST00000320785.10
ENST00000574165.1
kinesin family member 1C
chr1_+_35931076 0.09 ENST00000397828.3
ENST00000373191.9
argonaute RISC catalytic component 3
chr5_+_79612410 0.09 ENST00000423041.6
ENST00000504233.5
ENST00000453514.6
ENST00000428308.6
terminal nucleotidyltransferase 2
chr1_-_52366124 0.09 ENST00000371586.6
ENST00000284376.8
coiled-coil and C2 domain containing 1B
chr2_+_167868948 0.08 ENST00000392690.3
beta-1,3-galactosyltransferase 1
chr5_+_72816643 0.08 ENST00000337273.10
ENST00000523768.5
transportin 1
chr15_-_52569197 0.08 ENST00000563277.5
ENST00000566423.5
cAMP regulated phosphoprotein 19
chr7_-_99408548 0.07 ENST00000626285.1
ENST00000350498.8
PDGFA associated protein 1
chr3_+_49554436 0.07 ENST00000296452.5
bassoon presynaptic cytomatrix protein
chr11_+_117144277 0.07 ENST00000419197.6
ENST00000527958.6
ENST00000304808.10
ENST00000529887.6
ENST00000530272.1
platelet activating factor acetylhydrolase 1b catalytic subunit 2
chr17_-_1456149 0.07 ENST00000574295.1
ENST00000398970.5
ENST00000300574.3
CRK proto-oncogene, adaptor protein
chr2_+_203014842 0.06 ENST00000683969.1
ENST00000449802.5
neurobeachin like 1
chr5_+_151771884 0.05 ENST00000627077.2
ENST00000678976.1
ENST00000677408.1
ENST00000678070.1
ENST00000678964.1
ENST00000678925.1
ENST00000394123.7
ENST00000522761.6
ENST00000676827.1
G3BP stress granule assembly factor 1
chr16_+_69187125 0.05 ENST00000336278.8
syntrophin beta 2
chr4_+_93828746 0.05 ENST00000306011.6
atonal bHLH transcription factor 1
chr7_+_30284574 0.05 ENST00000323037.5
zinc and ring finger 2
chr2_-_219060914 0.05 ENST00000295731.7
Indian hedgehog signaling molecule
chr20_-_41300066 0.04 ENST00000436099.6
ENST00000309060.7
ENST00000373261.5
ENST00000436440.6
ENST00000560364.5
ENST00000560361.5
zinc fingers and homeoboxes 3
chr15_+_49423233 0.04 ENST00000560270.1
ENST00000267843.9
ENST00000560979.1
fibroblast growth factor 7
chr1_+_203795614 0.04 ENST00000367210.3
ENST00000432282.5
ENST00000453771.5
ENST00000367214.5
ENST00000639812.1
ENST00000367212.7
ENST00000332127.8
ENST00000550078.2
zinc finger CCCH-type containing 11A
zinc finger BED-type containing 6
chr2_+_231037500 0.04 ENST00000373640.5
chromosome 2 open reading frame 72
chr5_-_133612524 0.02 ENST00000265342.12
follistatin like 4
chr7_-_99466148 0.02 ENST00000394186.3
ENST00000359832.8
ENST00000449683.5
ENST00000292475.8
ENST00000488775.5
ENST00000523680.1
ENST00000430982.1
ENST00000413834.5
ATP synthase membrane subunit f
pentatricopeptide repeat domain 1
ATP5MF-PTCD1 readthrough
chr9_-_128771909 0.02 ENST00000291900.7
ENST00000414921.5
zyg-11 related cell cycle regulator
chr12_+_54497712 0.02 ENST00000293373.11
NCK associated protein 1 like
chr12_-_56221909 0.01 ENST00000394013.6
ENST00000345093.9
ENST00000551711.5
ENST00000552656.5
ring finger protein 41
chr1_+_15526813 0.01 ENST00000375838.5
ENST00000616884.4
ENST00000375849.5
ENST00000375847.8
DnaJ heat shock protein family (Hsp40) member C16
chr6_-_44297672 0.01 ENST00000371505.5
t-complex-associated-testis-expressed 1
chr3_+_52455589 0.01 ENST00000345716.9
ENST00000488380.5
ENST00000420808.2
nischarin
chr1_+_26826682 0.00 ENST00000374142.9
zinc finger DHHC-type palmitoyltransferase 18
chr22_+_39502237 0.00 ENST00000325301.7
mitochondrial elongation factor 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.3 GO:0016103 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653) regulation of skeletal muscle fiber differentiation(GO:1902809)
0.5 2.0 GO:0044837 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.5 1.9 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.4 1.2 GO:1904172 regulation of bleb assembly(GO:1904170) positive regulation of bleb assembly(GO:1904172)
0.3 2.1 GO:0031133 regulation of axon diameter(GO:0031133) oviduct development(GO:0060066)
0.3 1.1 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.3 0.8 GO:0021718 superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.2 1.0 GO:0051643 endoplasmic reticulum localization(GO:0051643)
0.2 1.1 GO:0007296 vitellogenesis(GO:0007296)
0.2 1.5 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.2 0.5 GO:0003358 noradrenergic neuron development(GO:0003358)
0.1 0.9 GO:0060979 vasculogenesis involved in coronary vascular morphogenesis(GO:0060979)
0.1 1.0 GO:0090170 regulation of Golgi inheritance(GO:0090170)
0.1 0.4 GO:0021526 medial motor column neuron differentiation(GO:0021526)
0.1 1.0 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.1 3.2 GO:0071481 cellular response to X-ray(GO:0071481)
0.1 1.5 GO:0002934 desmosome organization(GO:0002934)
0.1 0.6 GO:0048388 endosomal lumen acidification(GO:0048388)
0.1 0.3 GO:0098971 anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971)
0.1 0.6 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1 0.4 GO:0031064 negative regulation of histone deacetylation(GO:0031064)
0.1 0.9 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.1 0.4 GO:0045204 MAPK export from nucleus(GO:0045204)
0.1 0.6 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.1 1.2 GO:0045793 positive regulation of cell size(GO:0045793)
0.1 0.5 GO:0016926 protein desumoylation(GO:0016926)
0.1 0.3 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.1 0.4 GO:2000546 positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
0.1 0.3 GO:0032911 negative regulation of transforming growth factor beta1 production(GO:0032911)
0.1 0.7 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.1 0.2 GO:1904761 negative regulation of myofibroblast differentiation(GO:1904761)
0.1 0.2 GO:0060151 peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152)
0.1 0.2 GO:0043375 negative regulation of cellular pH reduction(GO:0032848) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671)
0.0 0.7 GO:0015074 DNA integration(GO:0015074)
0.0 0.3 GO:0007028 cytoplasm organization(GO:0007028)
0.0 0.1 GO:1904806 regulation of protein oxidation(GO:1904806) positive regulation of protein oxidation(GO:1904808)
0.0 0.4 GO:0099525 presynaptic dense core granule exocytosis(GO:0099525)
0.0 0.1 GO:1901355 response to rapamycin(GO:1901355)
0.0 0.8 GO:0003334 keratinocyte development(GO:0003334)
0.0 1.6 GO:0015012 heparan sulfate proteoglycan biosynthetic process(GO:0015012)
0.0 0.5 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.0 0.6 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.5 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.0 0.3 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.0 0.4 GO:0002863 positive regulation of inflammatory response to antigenic stimulus(GO:0002863)
0.0 0.4 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.4 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.5 GO:0032354 response to follicle-stimulating hormone(GO:0032354)
0.0 0.9 GO:1902751 positive regulation of cell cycle G2/M phase transition(GO:1902751)
0.0 0.8 GO:1904659 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.0 0.4 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 1.8 GO:0035306 positive regulation of dephosphorylation(GO:0035306) positive regulation of protein dephosphorylation(GO:0035307)
0.0 0.2 GO:1990034 calcium ion export from cell(GO:1990034)
0.0 0.9 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.0 0.3 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.0 0.5 GO:0032495 response to muramyl dipeptide(GO:0032495)
0.0 0.2 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.6 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.0 GO:0042668 auditory receptor cell fate determination(GO:0042668)
0.0 0.3 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.0 GO:0016539 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
0.0 0.3 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.0 0.4 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.0 0.6 GO:0046039 negative regulation of adenylate cyclase activity(GO:0007194) GTP metabolic process(GO:0046039)
0.0 0.1 GO:0090625 mRNA cleavage involved in gene silencing by siRNA(GO:0090625)
0.0 0.1 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0 0.5 GO:0071431 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.0 0.0 GO:0060437 lung growth(GO:0060437) regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.2 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.3 2.0 GO:0097149 centralspindlin complex(GO:0097149)
0.2 1.5 GO:0032584 growth cone membrane(GO:0032584)
0.2 1.2 GO:0005826 actomyosin contractile ring(GO:0005826)
0.2 0.8 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.1 0.5 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.1 1.0 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 0.6 GO:0005683 U7 snRNP(GO:0005683)
0.1 0.4 GO:0044305 calyx of Held(GO:0044305)
0.0 0.7 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.6 GO:0042588 zymogen granule(GO:0042588)
0.0 0.2 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.5 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.3 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.0 2.0 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.0 0.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.4 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.1 GO:0031931 TORC1 complex(GO:0031931)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.3 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.5 1.9 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.3 1.6 GO:0001888 glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0001888)
0.3 1.1 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.3 0.8 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.2 0.9 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.2 0.6 GO:0071209 U7 snRNA binding(GO:0071209)
0.2 0.8 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.1 0.5 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.1 0.9 GO:1990226 histone methyltransferase binding(GO:1990226)
0.1 1.4 GO:0046790 virion binding(GO:0046790)
0.1 0.4 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.1 0.4 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.1 0.4 GO:0016807 cysteine-type carboxypeptidase activity(GO:0016807) cysteine-type exopeptidase activity(GO:0070004)
0.1 0.6 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 0.3 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.1 0.8 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.1 1.2 GO:0070411 I-SMAD binding(GO:0070411)
0.1 0.4 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 0.7 GO:0000182 rDNA binding(GO:0000182)
0.0 0.6 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.3 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.3 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 0.3 GO:0043813 phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813)
0.0 0.4 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.3 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 1.0 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 1.0 GO:0000146 microfilament motor activity(GO:0000146)
0.0 0.5 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.3 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.4 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.5 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0 0.1 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.0 0.2 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.6 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.1 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.0 1.5 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.4 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.5 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.7 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.3 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.9 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.8 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 2.2 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.1 2.1 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 2.9 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 2.3 PID AURORA B PATHWAY Aurora B signaling
0.0 2.0 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.6 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.5 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.9 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.5 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 1.1 PID BMP PATHWAY BMP receptor signaling
0.0 0.3 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.5 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.5 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 1.0 PID RB 1PATHWAY Regulation of retinoblastoma protein

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.1 1.9 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.1 1.2 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 0.9 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.1 1.4 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 2.2 REACTOME KINESINS Genes involved in Kinesins
0.1 0.7 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.1 3.2 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 1.1 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 3.3 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.6 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 1.0 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 2.7 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.8 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.6 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 0.6 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.7 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.4 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 0.5 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.2 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.4 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.4 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.3 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.6 REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.0 0.3 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.6 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.5 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity